Role of chloride-homeostasis in the inhibitory control of neuronal network oscillators.

abstract：:1. The kinetic properties of embryonic Xenopus spinal cord neuron N-methyl-D-aspartate (NMDA)-activated receptors (NMDAR) were examined at the single-channel level. These receptors have a main conductance state of 50 pS and make occasional sojourns to a subconductance level of approximately 40 pS. The open channel lif...

journal_title：Journal of neurophysiology

authors： Zhang Y,Auerbach A

更新日期：1995-07-01 00:00:00

abstract：:Evaluation of confidence about one's knowledge is key to the brain's ability to monitor cognition. To investigate the neural mechanism of confidence assessment, we examined a biologically realistic spiking network model and found that it reproduced salient behavioral observations and single-neuron activity data from a...

journal_title：Journal of neurophysiology

authors： Wei Z,Wang XJ

更新日期：2015-07-01 00:00:00

abstract：:Exposure to odorants results in a rapid (<10 s) reduction in odor-evoked activity in the rat piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To further understand this form of cortical plasticity, a detailed analysis of its odor specificity was performed. Habituation of o...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-01-01 00:00:00

abstract：:The macaque middle temporal area (MT) is exquisitely sensitive to visual motion and there is a large amount of evidence that neural activity in MT is tightly correlated with the perception of motion. The mechanisms by which MT neurons achieve their directional selectivity, however, have received considerably less atte...

journal_title：Journal of neurophysiology

authors： Krekelberg B,Albright TD

更新日期：2005-05-01 00:00:00

abstract：:We studied two human subjects with total deafferentation of one upper limb secondary to traumatic multiple cervical root avulsions. Both subjects developed a phantom limb and underwent elective amputation of the paralyzed, deafferentated limb. Psychophysical study revealed in each subject an area of skin in the pector...

journal_title：Journal of neurophysiology

authors： Kew JJ,Halligan PW,Marshall JC,Passingham RE,Rothwell JC,Ridding MC,Marsden CD,Brooks DJ

更新日期：1997-05-01 00:00:00

abstract：:Swallow-evoked potentials in the preganglionic vagal fibers were studied using the single-fiber recording technique in anesthetized opossums. Swallows were evoked by tactile pharyngeal stimulation or electrical stimulation of the cut central end of the superior laryngeal nerve (SLN). Swallowing activity was recorded b...

journal_title：Journal of neurophysiology

authors： Gidda JS,Goyal RK

更新日期：1984-12-01 00:00:00

abstract：:Electrical transmission is a dynamically regulated form of communication and key to synchronizing neuronal activity. The bag cell neurons of Aplysia are a group of electrically coupled neuroendocrine cells that initiate ovulation by secreting egg-laying hormone during a prolonged period of synchronous firing called th...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Standage D,Groten CJ,Blohm G,Magoski NS

更新日期：2015-02-01 00:00:00

abstract：:A plaid pattern is formed when two sinusoidal gratings of different orientations are added together. Previous work has shown that V1 neurons selectively encode the direction and orientation of the component gratings in a moving plaid but not the direction of the plaid itself (Movshon et al. 1985). We recorded the resp...

journal_title：Journal of neurophysiology

authors： Tinsley CJ,Webb BS,Barraclough NE,Vincent CJ,Parker A,Derrington AM

更新日期：2003-08-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperatu...

journal_title：Journal of neurophysiology

authors： Smotherman MS,Narins PM

更新日期：1998-01-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

journal_title：Journal of neurophysiology

authors： Bergey GK,Bigalke H,Nelson PG

更新日期：1987-01-01 00:00:00

abstract：:1. The response to an optimally oriented stimulus of both simple and complex cells in the cat's striate visual cortex (area 17) can be suppressed by the superposition of an orthogonally oriented drifting grating. This effect is referred to as cross-orientation suppression. We have examined the spatial organization and...

journal_title：Journal of neurophysiology

authors： DeAngelis GC,Robson JG,Ohzawa I,Freeman RD

更新日期：1992-07-01 00:00:00

abstract：:The responses of many neurons in primary visual cortex are modulated by stimuli outside the classical receptive field in ways that may contribute to integrative processes like scene segmentation. To explore this issue, single-unit neuronal responses were recorded in monkey cortical areas V1 and V2 to visual stimuli co...

journal_title：Journal of neurophysiology

authors： Marcus DS,Van Essen DC

更新日期：2002-11-01 00:00:00

abstract：:The aim of this study was to determine whether neuronal activity in the macaque supplementary eye field (SEF) is influenced by the rule used for saccadic target selection. Two monkeys were trained to perform a variant of the memory-guided saccade task in which any of four visible dots (rightward, upward, leftward, and...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN,Ventura V,Carta R,Kass RE

更新日期：2000-09-01 00:00:00

abstract：:The responses of cortical neurons to repeated presentation of a stimulus are highly variable, yet correlated. These "noise correlations" reflect a low-dimensional structure of population dynamics. Here, we examine noise correlations in 22,705 pairs of neurons in primary visual cortex (V1) of anesthetized cats, during ...

journal_title：Journal of neurophysiology

authors： Schulz DP,Sahani M,Carandini M

更新日期：2015-08-01 00:00:00

abstract：:The recurrent mossy fiber pathway of the dentate gyrus expands dramatically in the epileptic brain and serves as a mechanism for synchronization of granule cell epileptiform activity. It has been suggested that this pathway also promotes epileptiform activity by inhibiting GABA(A) receptor function through release of ...

journal_title：Journal of neurophysiology

authors： Molnár P,Nadler JV

更新日期：2001-05-01 00:00:00

abstract：:The distribution of functional neurotransmitter receptors is an important determinant of neuronal information processing. To map the location of functional glutamate and GABA receptors on individual hippocampal neurons, we photolyzed "caged" glutamate and GABA while measuring the electrical currents resulting from act...

journal_title：Journal of neurophysiology

authors： Pettit DL,Augustine GJ

更新日期：2000-07-01 00:00:00

abstract：:In this study we present further evidence supporting the reciprocal nature of output effects on forearm flexor and extensor muscles from single corticomotoneuronal (CM) cells. Spike-triggered averaging of rectified EMG activity was used to test the output effects of 105 motor cortex cells in two rhesus monkeys (Macaca...

journal_title：Journal of neurophysiology

authors： Kasser RJ,Cheney PD

更新日期：1985-04-01 00:00:00

abstract：:Our group set out to develop a sensitive technique, capable of detecting output changes from the posterior fossa following a motor acquisition task. Transcranial magnetic stimulation (TMS) was applied over the right cerebellar cortex 5 ms in advance of test stimuli over the left cerebral motor cortex (M1), suppressing...

journal_title：Journal of neurophysiology

authors： Baarbé J,Yielder P,Daligadu J,Behbahani H,Haavik H,Murphy B

更新日期：2014-02-01 00:00:00

abstract：:The structural elements of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) signaling pathway have been described in the vestibular peripheral system. However, the functions of NO in the vestibular endorgans are still not clear. We evaluated the action of NO on the Ca(2+) currents in hair cells isolated from ...

journal_title：Journal of neurophysiology

authors： Almanza A,Navarrete F,Vega R,Soto E

更新日期：2007-02-01 00:00:00

abstract：:1. The lateral geniculate nucleus is the primary thalamic relay through which retinal signals pass en route to cortex. This relay is gated and can be suppressed by activity among local inhibitory neurons that use gamma-aminobutyric acid (GABA) as a neurotransmitter. In the cat, a major source of this GABAergic inhibit...

journal_title：Journal of neurophysiology

authors： Uhlrich DJ,Cucchiaro JB,Humphrey AL,Sherman SM

更新日期：1991-06-01 00:00:00

abstract：:We have previously demonstrated that neurons R3-14 of the Aplysia abdominal ganglia specifically express a gene encoding a 108-amino acid neuropeptide precursor. This precursor is postranslationally processed by cleavage of a signal sequence and two internal dibasic residues resulting in three peptides. The peptide pr...

journal_title：Journal of neurophysiology

authors： Campanelli JT,Scheller RH

更新日期：1987-04-01 00:00:00

abstract：:A preparation is described in which the thoracic ganglia of the crayfish are isolated together with the thoracocoxal muscle receptor organ (TCMRO) of the fourth leg. This preparation allows intracellular analysis of both centrally generated and reflex activity in leg motor neurons (MNs). The isolated thoracic ganglia ...

journal_title：Journal of neurophysiology

authors： Sillar KT,Skorupski P

更新日期：1986-04-01 00:00:00

abstract：:Neurons of the avian nucleus laminaris (NL) compute the interaural time difference (ITD) by detecting coincident arrivals of binaural signals with submillisecond accuracy. The cellular mechanisms for this temporal precision have long been studied theoretically and experimentally. The myelinated axon initial segment in...

journal_title：Journal of neurophysiology

authors： Ashida G,Abe K,Funabiki K,Konishi M

更新日期：2007-03-01 00:00:00

abstract：:The countermanding saccade task has been used in many studies to investigate the neural mechanisms that underlie the decision to execute or restrain rapid eye movements. In this task, the presentation of a saccade target is sometimes followed by the appearance of a stop cue that indicates that the subject should cance...

journal_title：Journal of neurophysiology

authors： Walton MM,Gandhi NJ

更新日期：2006-10-01 00:00:00

abstract：:In songbirds, the basal ganglia outflow nucleus LMAN is a cortical analog that is required for several forms of song plasticity and learning. Moreover, in adults, inactivating LMAN can reverse the initial expression of learning driven via aversive reinforcement. In the present study, we investigated how LMAN contribut...

journal_title：Journal of neurophysiology

authors： Warren TL,Tumer EC,Charlesworth JD,Brainard MS

更新日期：2011-10-01 00:00:00

abstract：:1. The modulation of reflex responses in up to 10 simultaneously recorded hindlimb muscles was studied in unrestrained cats walking on a treadmill. Single electrical shocks of various strengths were applied to different skin areas of teh hindlimb at different times of the step cycle while the resulting EMG responses w...

journal_title：Journal of neurophysiology

authors： Duysens J,Loeb GE

更新日期：1980-11-01 00:00:00

abstract：:The role of GAT-3 transporters in regulating GABA(A) receptor-mediated inhibition was examined in the rat neocortex using an in vitro slice preparation. Pharmacologically isolated GABA(A) receptor-mediated responses were recorded from layer V neocortical pyramidal cells, and the effects of SNAP-5114, a GAT-3 GABA tran...

journal_title：Journal of neurophysiology

authors： Kinney GA

更新日期：2005-12-01 00:00:00

abstract：:Lower limb paralysis from spinal cord injury (SCI) or neurological disease carries a poor prognosis for recovery and remains a large societal burden. Neurophysiological and neuroprosthetic research have the potential to improve quality of life for these patients; however, the lack of an ethical and sustainable nonhuma...

journal_title：Journal of neurophysiology

authors： Krucoff MO,Zhuang K,MacLeod D,Yin A,Byun YW,Manson RJ,Turner DA,Oliveira L,Lebedev MA

更新日期：2017-09-01 00:00:00