Neuronal activity in macaque supplementary eye field during planning of saccades in response to pattern and spatial cues.

abstract：:Performance in behavioral tasks is influenced by temporal expectations shaped by the temporal structure of the task. Such implicit temporal preparation is reflected in slow brain potentials and electroencephalographic oscillations and is attributed to interval timing mechanisms that probably depend on intact basal gan...

journal_title：Journal of neurophysiology

authors： Praamstra P,Pope P

更新日期：2007-11-01 00:00:00

abstract：:Persistent spiking in response to a discrete stimulus is considered to reflect the active maintenance of a memory for that stimulus until a behavioral response is made. This response pattern has been reported in learning paradigms that impose a temporal gap between stimulus presentation and behavioral response, includ...

journal_title：Journal of neurophysiology

authors： Siegel JJ

更新日期：2014-11-01 00:00:00

abstract：:Complex movements are generally thought to consist of a series of simpler elements. If this is so, how does the sensorimotor system assemble the pieces? This study recorded and evaluated sequences of arm movements to various targets placed in three-dimensional (3D) space. Subjects performed sequences consisting of sin...

journal_title：Journal of neurophysiology

authors： Klein Breteler MD,Hondzinski JM,Flanders M

更新日期：2003-06-01 00:00:00

abstract：:The mechanical state encoded by slowly adapting type 1 mechanoreceptors (SAI) during indentation was examined using an isolated preparation in a rat model. Skin and its intact innervation were harvested from the medial thigh of the rat hindlimb and placed in a dish, with the corium side down, containing synthetic inte...

journal_title：Journal of neurophysiology

authors： Ge W,Khalsa PS

更新日期：2002-04-01 00:00:00

abstract：:Neurons in both the lateral intraparietal area (LIP) of the monkey parietal cortex and the intermediate layers of the superior colliculus (SC) are activated well in advance of the initiation of saccadic eye movements. To determine whether there is a progression in the covert processing for saccades from area LIP to SC...

journal_title：Journal of neurophysiology

authors： Paré M,Wurtz RH

更新日期：2001-06-01 00:00:00

abstract：:The cannabinoid receptor CB1 is found in abundance in brain neurons, whereas CB2 is essentially expressed outside the brain. In the neocortex, CB1 is observed predominantly on large cholecystokinin (CCK)-expressing interneurons. However, physiological evidence suggests that functional CB1 are present on other neocorti...

journal_title：Journal of neurophysiology

authors： Hill EL,Gallopin T,Férézou I,Cauli B,Rossier J,Schweitzer P,Lambolez B

更新日期：2007-04-01 00:00:00

abstract：:Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K+ current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K+ ions were investigated in vitro with the whole cell patch-cla...

journal_title：Journal of neurophysiology

authors： Pelz C,Jander J,Rosenboom H,Hammer M,Menzel R

更新日期：1999-04-01 00:00:00

abstract：:Our mental representation of object categories is hierarchically organized, and our rapid and seemingly effortless categorization ability is crucial for our daily behavior. Here, we examine responses of a large number (>600) of neurons in monkey inferior temporal (IT) cortex with a large number (>1,000) of natural and...

journal_title：Journal of neurophysiology

authors： Kiani R,Esteky H,Mirpour K,Tanaka K

更新日期：2007-06-01 00:00:00

abstract：:An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded...

journal_title：Journal of neurophysiology

authors： Compte A,Constantinidis C,Tegner J,Raghavachari S,Chafee MV,Goldman-Rakic PS,Wang XJ

更新日期：2003-11-01 00:00:00

abstract：:1. Single-unit electrical activity has been recorded from 34 dorsal horn neurons in the sacral segments (S1-2) of the spinal cord in halothane-anesthetized rats. All of the neurons had cutaneous receptive fields (RFs) on the rat's tail. The neurons were classified according to their responses to both innocuous and nox...

journal_title：Journal of neurophysiology

authors： Laird JM,Cervero F

更新日期：1990-05-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparations provide an unparalleled opportunity to observe and control neural circuits. To investigate how neural circuits produce behavior, these m...

journal_title：Journal of neurophysiology

authors： Sanders JI,Kepecs A

更新日期：2012-12-01 00:00:00

abstract：:1. The first experiment of this study determined the effects of low-frequency stimulation of the monkey superior colliculus on spontaneous saccades in the dark. Stimulation trains, subthreshold for eliciting short-latency fixed-vector saccades, were highly effective at biasing the metrics (direction and amplitude) of ...

journal_title：Journal of neurophysiology

authors： Glimcher PW,Sparks DL

更新日期：1993-03-01 00:00:00

abstract：:We assessed synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) properties during synaptogenesis to describe the development of individual glutamatergic synapses on rat hippocampal CA1 principal neurons. Pharmacologically isolated AMPAR-mediated glutamatergic synaptic currents [evoked by stimul...

journal_title：Journal of neurophysiology

authors： Stubblefield EA,Benke TA

更新日期：2010-10-01 00:00:00

abstract：:The caudal primate prefrontal cortex (PFC) is involved in target selection and visually guided saccades through both covert attention and overt orienting eye movements. Unilateral damage to the caudal PFC often leads to decreased awareness of a contralesional target alone, referred to as "neglect," or when it is prese...

journal_title：Journal of neurophysiology

authors： Adam R,Johnston K,Everling S

更新日期：2019-08-01 00:00:00

abstract：:1. The aim of this study was to characterize the signals transmitted by neurons of the medial vestibular nucleus (MVN) to the middle zone of the flocculus in alert cats. 2. Bipolar stimulating electrodes were implanted into the middle zone of each flocculus, because this zone is known to be involved in the control of ...

journal_title：Journal of neurophysiology

authors： Cheron G,Escudero M,Godaux E

更新日期：1996-09-01 00:00:00

abstract：:Limb movement-related neurons in the cerebellar nuclei (CN) typically produce bursts of discharge in association with movement. Consequently, given the inhibitory nature of the Purkinje cell (PC) projection to CN, it is puzzling that only a minority of movement-related PCs pause; the majority burst. Some of the moveme...

journal_title：Journal of neurophysiology

authors： Holdefer RN,Houk JC,Miller LE

更新日期：2005-01-01 00:00:00

abstract：:In humans, functional magnetic resonance imaging (fMRI) activity in the anterior cingulate cortex (ACC) and the nucleus accumbens (NAc) appears to reflect affective and motivational aspects of pain. The responses of this reward-aversion circuit to relief of pain, however, have not been investigated in detail. Moreover...

journal_title：Journal of neurophysiology

authors： Becerra L,Navratilova E,Porreca F,Borsook D

更新日期：2013-09-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:Previous studies have shown that a subset of neurons in the rat anterodorsal thalamus discharge as a function of the animal's head direction (HD) in the horizontal plane, independent of the animal's location and behavior. These cells have consistent firing properties across a wide range of conditions and cell discharg...

journal_title：Journal of neurophysiology

authors： Taube JS

更新日期：2010-09-01 00:00:00

abstract：:Primary auditory cortex (A1) neurons are believed not to carry much information about tonal offsets because A1 neurons in barbiturate-anesthetized animals are usually described as having only onset responses. We investigated tonal offset responses in comparison with onset responses in the caudal part of A1 of awake ca...

journal_title：Journal of neurophysiology

authors： Qin L,Chimoto S,Sakai M,Wang J,Sato Y

更新日期：2007-05-01 00:00:00

abstract：:1. Responses of complex cells in cat striate cortex were studied with flashed light slit stimuli. The responses to slits flashed in different positions in the receptive field were assessed quantitatively before and after periods of prolonged stimulation of one small region of the receptive field. This type of prolonge...

journal_title：Journal of neurophysiology

authors： Marlin S,Douglas R,Cynader M

更新日期：1993-06-01 00:00:00

abstract：:Trimming all whiskers except two on one side of an adult rat's face results in cortical plasticity in which the spared whiskers, D2 and one D-row surround whisker (either D1 or D3), evoked responses containing more spikes than the response evoked by the cut whisker (called whisker pairing plasticity). Previously we ha...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Egli M,Stonecypher M,Wiley RG,Ebner FF

更新日期：2000-10-01 00:00:00

abstract：:Spontaneous calcium oscillations in mushroom bodies of late stage pupal and adult Drosophila brains have been implicated in memory consolidation during olfactory associative learning. This study explores the cellular mechanisms regulating calcium dynamics in Kenyon cells, principal neurons in mushroom bodies. Fura-2 i...

journal_title：Journal of neurophysiology

authors： Jiang SA,Campusano JM,Su H,O'Dowd DK

更新日期：2005-07-01 00:00:00

abstract：:The effect of stimulation of the laterodorsal tegmental nucleus (LDT) on the activity of single neurons in the dorsal lateral geniculate nucleus was studied in rats anesthetized with urethan. The LDT is the largest aggregation of cholinergic neurons in the brain stem that project to the thalamus, and in the rat is suf...

journal_title：Journal of neurophysiology

authors： Kayama Y,Takagi M,Ogawa T

更新日期：1986-11-01 00:00:00

abstract：:1. Spontaneous saccades, vestibuloocular responses (VOR), and optokinetic nystagmus were recorded in three squirrel monkeys before and after chemical or electrolytic lesion of the posterior commissure (PC). 2. PC lesions produced abnormal vertical eye movements, in particular, 1) Postsaccadic drifts, and 2) VOR gain r...

journal_title：Journal of neurophysiology

authors： Partsalis AM,Highstein SM,Moschovakis AK

更新日期：1994-06-01 00:00:00

abstract：:Reaching to grasp is of fundamental importance to primate motor behavior and requires coordinating hand preshaping with limb transport and grasping. We aimed to clarify the role of cerebellar output via the magnocellular red nucleus (RNm) to the control of reaching to grasp. Rubrospinal fibers originating from RNm con...

journal_title：Journal of neurophysiology

authors： van Kan PL,McCurdy ML

更新日期：2001-04-01 00:00:00

abstract：:1. A variety of pharmacological tests indicate that the neuromuscular junction between the salivary burster neuron (SB) and the salivary duct muscle (SD) in the terrestrial mollusk Limax maximus is cholinergic. These include the effects of curare, atropine, and hexamethonium. 2. Exogenously applied choline can act bot...

journal_title：Journal of neurophysiology

authors： Barry SR,Gelperin A

更新日期：1982-08-01 00:00:00

abstract：:The basal ganglia participate in motor functions and are implicated in the pathophysiology of movement disorders. It has been shown in primates that the activity of many neurons in one of the basal ganglia output nuclei, the internal segment of the globus pallidus, changes with active or passive movements. The involve...

journal_title：Journal of neurophysiology

authors： Wichmann T,Kliem MA

更新日期：2004-02-01 00:00:00

abstract：:1. The synaptic inputs to sustained OFF-center ganglion cells of the mudpuppy retina were studied using a superfused retina-eye-cup preparation. Intra- and extracellular electrophysiological recording techniques were carried out during bath application of 2-amino-4-phosphonobutyrate (APB), a glutamate analog that sele...

journal_title：Journal of neurophysiology

authors： Arkin MS,Miller RF

更新日期：1988-09-01 00:00:00