Movement-related discharge in the cerebellar nuclei persists after local injections of GABA(A) antagonists.

abstract：:In this tribute to Reggie Edgerton, I briefly review the spinal mechanisms that coordinate locomotion and the interaction between the different sensory mechanisms that help coordinate the locomotor movements and the central locomotor network. The step cycle has four distinct parts, the support phase, the lift off, the...

journal_title：Journal of neurophysiology

authors： Grillner S

更新日期：2020-12-23 00:00:00

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:1. Bicuculline-induced epileptiform bursts in slices of neocortical tissue resected from children (3 mo to 14 yr) undergoing neurosurgical treatment for intractable epilepsy were studied with conventional intracellular recording techniques. The purposes of this study were to characterize the bursts evoked in immature ...

journal_title：Journal of neurophysiology

authors： Kim YI,Peacock WJ,Dudek FE

更新日期：1993-11-01 00:00:00

abstract：:An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded...

journal_title：Journal of neurophysiology

authors： Compte A,Constantinidis C,Tegner J,Raghavachari S,Chafee MV,Goldman-Rakic PS,Wang XJ

更新日期：2003-11-01 00:00:00

abstract：:Twenty-four slowly adapting type 1 (SA1) and 26 rapidly adapting (RA) cutaneous mechanoreceptive afferents in the rhesus monkey were studied with an array of independently controlled, punctate probes that covered an entire fingerpad. Each afferent had a receptive field (RF) on a single fingerpad and was studied at 73 ...

journal_title：Journal of neurophysiology

authors： Vega-Bermudez F,Johnson KO

更新日期：1999-06-01 00:00:00

abstract：:Humans maneuver easily over uneven terrain. To maintain smooth and efficient gait the motor system needs to adapt the locomotor output to the walking environment. In the present study we investigate the role of sensory feedback in adjusting the soleus muscle activity during overground walking in 19 healthy volunteers....

journal_title：Journal of neurophysiology

authors： Af Klint R,Nielsen JB,Sinkjaer T,Grey MJ

更新日期：2009-04-01 00:00:00

abstract：:The whole cell patch-clamp technique in combination with the slice preparation was used to investigate the electrophysiological properties of pigeon semicircular canal sensory and supporting cells. These properties were also characterized in regenerating neuroepithelia of pigeons preinjected with streptomycin to kill ...

journal_title：Journal of neurophysiology

authors： Masetto S,Correia MJ

更新日期：1997-10-01 00:00:00

abstract：:There are at least two respiration-related rhythm generators in the medulla: the pre-Bötzinger complex, which produces inspiratory (Insp) neuron bursts, and the parafacial respiratory group (pFRG), which produces predominantly preinspiratory (Pre-I) neuron bursts. The pFRG Pre-I neuron activity has not been correlated...

journal_title：Journal of neurophysiology

authors： Onimaru H,Kumagawa Y,Homma I

更新日期：2006-07-01 00:00:00

abstract：:It has recently become clear that microglia, the immune cells of the central nervous system, are far more active in the healthy brain than previously thought. Microglia facilitate many stages of brain development by shaping neuronal connectivity via synaptic elimination. Dysfunction of these same processes likely unde...

journal_title：Journal of neurophysiology

authors： Whitelaw BS

更新日期：2018-01-01 00:00:00

abstract：:Multisite optical recording has revealed that the neural excitation wave induced by a sensory stimulation begins at a focus and propagates in the cortex. This wave is considered to be important for computation in the sensory cortex, particularly the integration of sensory information; however, the nature of this wave ...

journal_title：Journal of neurophysiology

authors： Hama N,Kawai M,Ito SI,Hirota A

更新日期：2018-05-01 00:00:00

abstract：:Effects of spaceflight on Rhesus quadrupedal locomotion after return to 1G. Locomotor performance, activation patterns of the soleus (Sol), medial gastrocnemius (MG), vastus lateralis (VL), and tibialis anterior (TA) and MG tendon force during quadrupedal stepping were studied in adult Rhesus before and after 14 days ...

journal_title：Journal of neurophysiology

authors： Recktenwald MR,Hodgson JA,Roy RR,Riazanski S,McCall GE,Kozlovskaya I,Washburn DA,Fanton JW,Edgerton VR

更新日期：1999-05-01 00:00:00

abstract：:1. Red rod photoreceptors in the toad retina, which are known to be physiologically coupled, were examined for interreceptor contacts. 2. A dense network of large gap junctions was found between the inner segments of red rods, this being the only specialized site of contact that was observed between rods. Each red rod...

journal_title：Journal of neurophysiology

authors： Gold GH,Dowling JE

更新日期：1979-01-01 00:00:00

abstract：:The oculomotor system is well understood compared with other motor systems; however, we do not yet know the spatial details of sensory to motor transformations. This study addresses this issue by quantifying the spatial relationships between visual and motor responses in the superior colliculus (SC), a midbrain struct...

journal_title：Journal of neurophysiology

authors： Marino RA,Rodgers CK,Levy R,Munoz DP

更新日期：2008-11-01 00:00:00

abstract：:1. Monkeys were trained to react to an arm perturbation according to an instruction delivered prior to the perturbation. There were two possible instructions (push or pull), and monkeys learned to respond accordingly regardless of the direction (push or pull) of the triggering perturbation. 2. Pyramidal tract neurons ...

journal_title：Journal of neurophysiology

authors： Evarts EV,Tanji J

更新日期：1976-09-01 00:00:00

abstract：:Field potential recording was used to investigate properties of synaptic transmission and long-term potentiation (LTP) at Schaffer collateral-CA1 synapses in both hippocampal slices of mutant mice in which the alpha-subunit of the olfactory cyclic nucleotide-gated channel (alpha3/OCNC)1 was rendered null and also in s...

journal_title：Journal of neurophysiology

authors： Parent A,Schrader K,Munger SD,Reed RR,Linden DJ,Ronnett GV

更新日期：1998-06-01 00:00:00

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:The brain stem nucleus locus coeruleus (LC) is thought to modulate cortical excitability by norepinephrine (NE) release in LC forebrain targets. The effects of LC burst discharge, typically evoked by a strong excitatory input, on cortical ongoing activity are poorly understood. To address this question, we combined di...

journal_title：Journal of neurophysiology

authors： Marzo A,Totah NK,Neves RM,Logothetis NK,Eschenko O

更新日期：2014-06-15 00:00:00

abstract：:Circulating glucose levels significantly affect vagal neural activity, which is important in the regulation of pancreatic functions. Little is known about the mechanisms involved. This study investigates the neural pathways responsible for hypoglycemia-induced vagal efferent signaling to the pancreas and identifies th...

journal_title：Journal of neurophysiology

authors： Wu X,Gao J,Yan J,Owyang C,Li Y

更新日期：2004-04-01 00:00:00

abstract：:1. Many cells in the superior temporal sulcus (STS) of the monkey that represent the foveal region of the visual field discharge during pursuit eye movements. Damage to these areas produces a deficit in the maintenance of pursuit eye movements when the target towards the side of the brain with the lesion. In the prese...

journal_title：Journal of neurophysiology

authors： Komatsu H,Wurtz RH

更新日期：1989-07-01 00:00:00

abstract：:The contribution of ascending afferents to the control of speech movement was evaluated by applying unanticipated loads to the lower lip during the generation of combined upper lip-lower lip speech gestures. To eliminate potential contamination due to anticipation or adaptation, loads were applied randomly on only 10-...

journal_title：Journal of neurophysiology

authors： Abbs JH,Gracco VL

更新日期：1984-04-01 00:00:00

abstract：:Hilar mossy cells represent a unique population of local circuit neurons in the hippocampus and dentate gyrus. Here we use electrophysiological techniques in acute preparations of hippocampal slices to demonstrate that depolarization of a single hilar mossy cell can produce robust inhibition of local GABAergic afferen...

journal_title：Journal of neurophysiology

authors： Hofmann ME,Nahir B,Frazier CJ

更新日期：2006-11-01 00:00:00

abstract：:Red and green cones of two turtle species (Pseudemys scripta elegans and Chelydra serpentina) retina have been stained with Golgi procedures and examined by light microscopy of whole-mount tissue and by electron microscopy of serial thin sections. By light microscopy, red and green single cones appear indistinguishabl...

journal_title：Journal of neurophysiology

authors： Kolb H,Jones J

更新日期：1985-08-01 00:00:00

abstract：:1. The initial objective of this study was to determine whether respiratory-related neural assemblies exist in the brain stem midline. A second goal was to seek evidence for concurrent relationships among the neurons that could generate the detected synchrony. 2. Experiments were conducted on anesthetized, paralyzed, ...

journal_title：Journal of neurophysiology

authors： Lindsey BG,Hernandez YM,Morris KF,Shannon R,Gerstein GL

更新日期：1992-04-01 00:00:00

abstract：:1. The question of whether active uptake limits the duration of action of the inhibitory transmitter glycine has been addressed in vivo at inhibitory synapses on the goldfish Mauthner (M) cell. The kinetics of inhibitory postsynaptic potentials and inhibitory postsynaptic currents (IPSCs) evoked antidromically and by ...

journal_title：Journal of neurophysiology

authors： Titmus MJ,Korn H,Faber DS

更新日期：1996-04-01 00:00:00

abstract：:It is now well recognized that muscle activity can be induced even in the paralyzed lower limb muscles of persons with spinal cord injury (SCI) by imposing locomotion-like movements on both of their legs. Although the significant role of the afferent input related to hip joint movement and body load has been emphasize...

journal_title：Journal of neurophysiology

authors： Kawashima N,Nozaki D,Abe MO,Akai M,Nakazawa K

更新日期：2005-02-01 00:00:00

abstract：:The earliest neural response to a mechanical perturbation, the short-latency stretch response (R1: 20-45 ms), is known to exhibit "automatic gain-scaling" whereby its magnitude is proportional to preperturbation muscle activity. Because gain-scaling likely reflects an intrinsic property of the motoneuron pool (via the...

journal_title：Journal of neurophysiology

authors： Pruszynski JA,Kurtzer I,Lillicrap TP,Scott SH

更新日期：2009-08-01 00:00:00

abstract：:Evidence for a persistent Na+ current (I(NaP)) in the apical dendrite of neocortical neurons was sought with the use of fluorescence imaging to measure changes in intradendritic Na+ concentration. Neurons in neocortical brain slices were filled iontophoretically through an intracellular recording microelectrode with t...

journal_title：Journal of neurophysiology

authors： Mittmann T,Linton SM,Schwindt P,Crill W

更新日期：1997-08-01 00:00:00

abstract：:Similar to most visual animals, crabs perform proper avoidance responses to objects directly approaching them. The monostratified lobula giant neurons of type 1 (MLG1) of crabs constitute an ensemble of 14-16 bilateral pairs of motion-detecting neurons projecting from the lobula (third optic neuropile) to the midbrain...

journal_title：Journal of neurophysiology

authors： Oliva D,Tomsic D

更新日期：2014-09-15 00:00:00

abstract：:1. Noxious stimuli have been shown to produce a diffuse inhibition of nociresponsive neurons in the spinal and trigeminal dorsal horns. The present study sought to extend these electrophysiological studies of diffuse noxious inhibitory controls (DNIC) by determining the effect of a spatially remote noxious stimulus on...

journal_title：Journal of neurophysiology

authors： Morgan MM,Heinricher MM,Fields HL

更新日期：1994-09-01 00:00:00

abstract：:Although previous research with human and nonhuman primates has examined the neural correlates of performance monitoring, discrepancies in methodology have limited our ability to make cross-species generalizations. One major obstacle arises from the use of different behavioral responses and tasks across different prim...

journal_title：Journal of neurophysiology

authors： Reinhart RM,Carlisle NB,Kang MS,Woodman GF

更新日期：2012-05-01 00:00:00