Synaptic transmission and hippocampal long-term potentiation in olfactory cyclic nucleotide-gated channel type 1 null mouse.

abstract：:The purpose of this study was to examine changes in motor unit activity in the biceps brachii muscle after an initial (Bout 1) and repeated (Bout 2) session of eccentric exercise separated by 1 wk. Eight subjects (aged 22 ± 2 yr) participated in experimental assessments of neuromuscular function obtained before, immed...

journal_title：Journal of neurophysiology

authors： Dartnall TJ,Nordstrom MA,Semmler JG

更新日期：2011-03-01 00:00:00

abstract：:Tetanus neurotoxin (TeNT) cleaves synaptobrevin, a protein involved in synaptic vesicle docking and fusion, thereby preventing neurotransmitter release and causing a functional deafferentation. We injected TeNT into the lateral rectus muscle of adult cats at 0.5 or 5 ng/kg (low and high dose, respectively). In the per...

journal_title：Journal of neurophysiology

authors： Gonzalez-Forero D,de la Cruz RR,Delgado-Garcia JM,Alvarez FJ,Pastor AM

更新日期：2003-04-01 00:00:00

abstract：:Ankle inversions have been studied extensively during standing conditions. However, inversion traumas occur during more dynamic conditions, like walking. Therefore in this study sudden ankle inversions were elicited in 12 healthy subjects who stepped on a trap door while walking on a treadmill. First, 10 control trial...

journal_title：Journal of neurophysiology

authors： Nieuwenhuijzen PH,Duysens J

更新日期：2007-10-01 00:00:00

abstract：:Tissue injury in early life can produce distinctive effects on pain processing, but little is known about the underlying neural mechanisms. Neonatal inflammation modulates excitatory synapses in spinal nociceptive circuits, but it is unclear whether this results directly from altered afferent input. Here we investigat...

journal_title：Journal of neurophysiology

authors： Li J,Walker SM,Fitzgerald M,Baccei ML

更新日期：2009-10-01 00:00:00

abstract：:Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are responsible for the functional hyperpolarization-activated current (I(h)) in dorsal root ganglion (DRG) neurons, playing an important role in pain processing. We found that the known analgesic loperamide inhibited I(h) channels in rat DRG neurons. ...

journal_title：Journal of neurophysiology

authors： Vasilyev DV,Shan Q,Lee Y,Mayer SC,Bowlby MR,Strassle BW,Kaftan EJ,Rogers KE,Dunlop J

更新日期：2007-05-01 00:00:00

abstract：:Whole cell patch-clamp recordings were used to investigate the contribution of transient, low-threshold calcium currents (I(T)) to firing properties of hamster spinal dorsal horn neurons. I(T) was widely, though not uniformly, expressed by cells in Rexed's laminae I-IV and correlated with the pattern of action potenti...

journal_title：Journal of neurophysiology

authors： Ku WH,Schneider SP

更新日期：2011-11-01 00:00:00

abstract：:Detection and discrimination of odors generally, if not always, occurs against an odorous background. On any given inhalation, olfactory receptor neurons will be activated by features of both the target odorant and features of background stimuli. To identify a target odorant against a background therefore, the olfacto...

journal_title：Journal of neurophysiology

authors： Kadohisa M,Wilson DA

更新日期：2006-03-01 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:1. In alpha-chloralose-anesthetized cats the region surrounding the ventral posterolateral nucleus (VPL) of the thalamus was investigated to locate foci with input from the urinary bladder stimulated by application of intravesical pressure. The locations of the recording sites were verified in Nissl-stained histologic...

journal_title：Journal of neurophysiology

authors： Brüggemann J,Vahle-Hinz C,Kniffki KD

更新日期：1993-08-01 00:00:00

abstract：:Rats typically employ 4- to 12-Hz "whisking" movements of their vibrissae during tactile exploration. The intentional sampling of signals in this frequency range suggests that neural processing of tactile information may be differentially engaged in this bandwidth. We examined action potential responses in rat primary...

journal_title：Journal of neurophysiology

authors： Garabedian CE,Jones SR,Merzenich MM,Dale A,Moore CI

更新日期：2003-09-01 00:00:00

abstract：:The aim of this study is to assess brain activity measured during continuous performance of design tracing tasks. Three issues were addressed: identification of brain areas involved in performing maze and square tracing tasks, investigation of differences and similarities in these areas related to dominant and nondomi...

journal_title：Journal of neurophysiology

authors： van Mier H,Tempel LW,Perlmutter JS,Raichle ME,Petersen SE

更新日期：1998-10-01 00:00:00

abstract：:It is shown that the primate primary taste cortex represents not only taste but also information about many nontaste properties of oral stimuli. Of 1,122 macaque anterior insular/frontal opercular neurons recorded, 62 (5.5%) responded to oral stimuli. Of the orally responsive neurons, some (53%) represented the viscos...

journal_title：Journal of neurophysiology

authors： Verhagen JV,Kadohisa M,Rolls ET

更新日期：2004-09-01 00:00:00

abstract：:Our group set out to develop a sensitive technique, capable of detecting output changes from the posterior fossa following a motor acquisition task. Transcranial magnetic stimulation (TMS) was applied over the right cerebellar cortex 5 ms in advance of test stimuli over the left cerebral motor cortex (M1), suppressing...

journal_title：Journal of neurophysiology

authors： Baarbé J,Yielder P,Daligadu J,Behbahani H,Haavik H,Murphy B

更新日期：2014-02-01 00:00:00

abstract：:We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

journal_title：Journal of neurophysiology

authors： Hinder MR,Milner TE

更新日期：2007-11-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:Neural implants with large numbers of electrodes have become an important tool for examining brain functions. However, these devices typically displace a large intracranial volume compared with the neurons they record. This large size limits the density of implants, provokes tissue reactions that degrade chronic perfo...

journal_title：Journal of neurophysiology

authors： Egert D,Pettibone JR,Lemke S,Patel PR,Caldwell CM,Cai D,Ganguly K,Chestek CA,Berke JD

更新日期：2020-12-01 00:00:00

abstract：:Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimula...

journal_title：Journal of neurophysiology

authors： Lewis RF

更新日期：2016-12-01 00:00:00

abstract：:We measured synaptic responses to complex stimulus trains in the calyx of Held and used the data to test how well several vesicle-release models could capture the observed dynamics. We tested stimulation protocols consisting of Poisson-distributed activity with periodically changing mean frequencies, trains with const...

journal_title：Journal of neurophysiology

authors： Hermann J,Grothe B,Klug A

更新日期：2009-01-01 00:00:00

abstract：:1. Depolarization-induced elevations of intracellular calcium concentration ([Ca2+]i) were examined in slice-cultured hippocampal pyramidal and nonpyramidal cells of the CA3 region by combined intracellular and multisite fura-2 recording techniques. 2. In pyramidal cells, spiking activity induced by depolarizing curre...

journal_title：Journal of neurophysiology

authors： Knöpfel T,Gähwiler BH

更新日期：1992-09-01 00:00:00

abstract：:We examined the characteristics of heterosynaptic long-term depression (LTD) and depotentiation of previously established long-term potentiation (LTP) in the medial and lateral entorhinal afferents to the dentate gyrus in the awake rat. Rats were prepared for chronic recording of dentate gyrus evoked potentials to act...

journal_title：Journal of neurophysiology

authors： Doyère V,Srebro B,Laroche S

更新日期：1997-02-01 00:00:00

abstract：:Across the entire human body, postural tone might play its most critical role in the body's axis because the axis joins the four limbs and head into a single functioning unit during complex motor tasks as well as in static postures. Although postural tone is commonly viewed as low-level, tonic motor activity, we hypot...

journal_title：Journal of neurophysiology

authors： Gurfinkel V,Cacciatore TW,Cordo P,Horak F,Nutt J,Skoss R

更新日期：2006-11-01 00:00:00

abstract：:Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used as a measure of neuronal activity, despite an incomplete understanding of the hemodynamic and neural bases for BOLD signals. Recent work by Lee and colleagues investigated whether activating genetically specified neuro...

journal_title：Journal of neurophysiology

authors： Palmer HS

更新日期：2010-10-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:1. The responses of single neurons in the primary somatosensory cortex of the cat to brief air-pulse stimuli were quantitatively examined. These controlled natural stimuli activated almost exclusively rapidly adapting hair units which, on systematic movement of the stimulus through the receptive field, gave unit-respo...

journal_title：Journal of neurophysiology

authors： Laskin SE,Spencer WA

更新日期：1979-07-01 00:00:00

abstract：:Mesencephalic trigeminal (M-V) neurons are primary somatosensory neurons with somata located within the CNS, instead of in peripheral sensory ganglia. In amphibians, these unipolar cells are found within the optic tectum and have a single axon that runs along the mandibular branch of the trigeminal nerve. The axon has...

journal_title：Journal of neurophysiology

authors： Pratt KG,Aizenman CD

更新日期：2009-07-01 00:00:00

abstract：:1. A network of four pairs of interneurons, HN(1)-HN(4), times the heartbeat of the medicinal leech. The following model accounts for the stable phase relationships in the network and the network's response to perturbation, entrainment, and stimulation. 2. There are two centers of oscillation, one the HN(3) pair in th...

journal_title：Journal of neurophysiology

authors： Peterson EL

更新日期：1983-03-01 00:00:00

abstract：:With experience, an object can become behaviorally relevant and thereby quickly attract our interest when presented in a visual scene. A likely site of these learning effects is anterior inferior temporal (aIT) cortex, where neurons are thought to participate in the filtering of irrelevant information out of complex v...

journal_title：Journal of neurophysiology

authors： Jagadeesh B,Chelazzi L,Mishkin M,Desimone R

更新日期：2001-07-01 00:00:00

abstract：:The inferior olive is the sole source of the climbing fiber system, one of the two major afferent systems of the cerebellum; however, its exact role remains unknown. A longstanding hypothesis is that the inferior olive with its unique intrinsic rhythmic firing properties mediates motor timing. However, direct evidence...

journal_title：Journal of neurophysiology

authors： Liu T,Xu D,Ashe J,Bushara K

更新日期：2008-09-01 00:00:00

abstract：:1. The actions of hydrogen sulfide (HS-) on membrane and synaptic properties of dorsal raphe (DR) serotonergic cells were studied in the in vitro brain stem slice preparation, using intracellular sharp microelectrode and whole-cell recording techniques. 2. Sulfide produced two reversible, concentration-dependent effec...

journal_title：Journal of neurophysiology

authors： Kombian SB,Reiffenstein RJ,Colmers WF

更新日期：1993-07-01 00:00:00

abstract：:1. Mechanoreceptor neurons in spider (Cupiennlus salei) slit sense organ were examined by intracellular current- and voltageclarry recordings. Steps and pseudorandomly modulated displacement stimuli were delivered to the mechanosensitive cuticular slits. The resulting responses were used to determine the response dyna...

journal_title：Journal of neurophysiology

authors： Juusola M,French AS

更新日期：1995-12-01 00:00:00