Vestibular implants studied in animal models: clinical and scientific implications.

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:1. We define an extrinsic frame of reference to represent the location of a point in extrapersonal space relative to a human subject's shoulder, and we define an intrinsic frame of reference to represent the orientation of the arm and forearm. 2. We examined the relations between coordinates in the extrinsic and intri...

journal_title：Journal of neurophysiology

authors： Soechting JF,Flanders M

更新日期：1989-08-01 00:00:00

abstract：:During early development neuronal networks express slow oscillating synchronized activity. The activity can be driven by several, not necessarily mutually exclusive, mechanisms. Each mechanism might have distinctive consequences for the phenomenology, formation, or sustainment of the early activity pattern. Here we st...

journal_title：Journal of neurophysiology

authors： Baltz T,Herzog A,Voigt T

更新日期：2011-09-01 00:00:00

abstract：:Subacute and chronic changes in tonic GABAergic inhibition occur in human and experimental epilepsy. Less is known about how tonic inhibition is modulated over shorter time frames (seconds). We measured endogenous tonic GABA currents from cultured rat hippocampal neurons to evaluate how they are affected by 1) transie...

journal_title：Journal of neurophysiology

authors： Ransom CB,Tao W,Wu Y,Spain WJ,Richerson GB

更新日期：2013-02-01 00:00:00

abstract：:We are studying the functional "logic" of neuromodulatory actions in a simple central pattern generator (CPG)-effector system, the heart of the blue crab Callinectes sapidus. The rhythmic contractions of this heart are neurogenic, driven by rhythmic motor patterns generated by the cardiac ganglion (CG). Here we used a...

journal_title：Journal of neurophysiology

authors： Fort TJ,Brezina V,Miller MW

更新日期：2007-11-01 00:00:00

abstract：:Ion channel modulation by the peptide myomodulin (MM) has been demonstrated in a wide variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. This neural and muscular modulation has been shown to be important for shaping and modifying behavior. In this paper, we report that MM modulates several distinct ...

journal_title：Journal of neurophysiology

authors： Wang Y,Strong JA,Sahley CL

更新日期：1999-07-01 00:00:00

abstract：:1. Several heart interneurons (HN cells) of the leech nerve cord have impulse-initiation sites in every segmental ganglion through which their single axons pass. All these initiation sites are capable of producing rhythmic impulse bursts. However, under normal conditions a dominant primary initiation site in the gangl...

journal_title：Journal of neurophysiology

authors： Calabrese RL

更新日期：1980-11-01 00:00:00

abstract：:An important new study by Kvarta, Bradbrook, Dantrassy, Bailey, and Thompson (J Neurophysiol 114: 1713-1724, 2015) examined the effects of persistent stress and excessive glucocorticoid levels on hippocampal function and emotional behavior in rodents. The authors specifically implicate the temporoammonic pathway as be...

journal_title：Journal of neurophysiology

authors： McGinn MA,Pahng AR

更新日期：2017-02-01 00:00:00

abstract：:Reports of cholecystokinin (CCK) binding and expression of CCK receptors in neonatal rodent spinal cord suggest that CCK may influence neuronal excitability. In patch-clamp recordings from 19/21 ventral horn motoneurons in neonatal (PN 5-12 days) rat spinal cord slices, we noted a slowly rising and prolonged membrane ...

journal_title：Journal of neurophysiology

authors： Oz M,Yang KH,Shippenberg TS,Renaud LP,O'Donovan MJ

更新日期：2007-09-01 00:00:00

abstract：:1. Whole-cell recordings were performed on acutely isolated pyramidal neurons from rat sensorimotor cortex 2 to 21 days postnatal to study the expression of a tetrodotoxin (TTX) sensitive, voltage dependent, persistent Na+ current (INaP) during different stages of postnatal development. 2. INaP was activated positive ...

journal_title：Journal of neurophysiology

authors： Alzheimer C,Schwindt PC,Crill WE

更新日期：1993-01-01 00:00:00

abstract：:To perform goal-oriented hand movement, humans combine multiple sensory signals (e.g., vision and proprioception) that can be encoded in various reference frames (body centered and/or exo-centered). In a previous study (Tagliabue M, McIntyre J. PLoS One 8: e68438, 2013), we showed that, when aligning a hand to a remem...

journal_title：Journal of neurophysiology

authors： Arnoux L,Fromentin S,Farotto D,Beraneck M,McIntyre J,Tagliabue M

更新日期：2017-09-01 00:00:00

abstract：:One of the critical factors in determining network behavior of neurons is the influence of local circuit connections among interneurons. The short-term synaptic plasticity and the subtype of presynaptic calcium channels used at local circuit connections of inhibitory interneurons in CA1 were investigated using dual wh...

journal_title：Journal of neurophysiology

authors： Ali AB

更新日期：2011-03-01 00:00:00

abstract：:Capacitance measurements allow direct studies of exocytosis and endocytosis in single synaptic terminals isolated from bipolar neurons of goldfish retina. Extending the technique to intact bipolar cells, with their more complex morphology, requires information about the cells' electrotonic architecture. To this end, w...

journal_title：Journal of neurophysiology

authors： Mennerick S,Zenisek D,Matthews G

更新日期：1997-07-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:An increase in L-arginine hemolymph concentration acts as a postingestion signal inhibiting Aplysia feeding. At physiological concentrations (a 10-μM increase over background), the inhibitory effect of L-arginine is too weak to block feeding in hungry animals. However, a 10-μM increase in L-arginine concentration acts...

journal_title：Journal of neurophysiology

authors： Miller N,Saada R,Markovich S,Hurwitz I,Susswein AJ

更新日期：2011-04-01 00:00:00

abstract：:1. In a search for correlated fast rhythms in recurrent laryngeal (RL) expiratory (E) activities, we performed spectral and coherence analysis on bilateral RL nerve discharges in 54 midcollicular decerebrate, paralyzed cats. 2. Inspiratory (I) RL activities showed in almost all cases high-frequency oscillations (HFO, ...

journal_title：Journal of neurophysiology

authors： Huang WX,Christakos CN,Cohen MI,He Q

更新日期：1993-11-01 00:00:00

abstract：:The creation of several prestin knockout and knockin mouse lines has demonstrated the importance of the intrinsic outer hair cell membrane protein prestin to mammalian hearing. However, the structure of prestin remains largely unknown, with even its major features in dispute. Several studies have suggested that presti...

journal_title：Journal of neurophysiology

authors： Currall B,Rossino D,Jensen-Smith H,Hallworth R

更新日期：2011-11-01 00:00:00

abstract：:1. The responses of a total of 70 single neurons were recorded from the parabrachial nuclei (PBN) in awake rats. In 59 neurons, sapid stimuli (0.5 ml) elicited significant taste responses. Of these 59 neurons, 10 also had significant responses to water. The mean spontaneous rate of the taste neurons was 13.4 +/- 6.9 (...

journal_title：Journal of neurophysiology

authors： Nishijo H,Norgren R

更新日期：1990-04-01 00:00:00

abstract：:The capabilities of any sensory system are ultimately constrained by the properties of the sensory neurons: the ability to detect and represent stimuli is limited by noise due to spontaneous activity, and optimal decoding in downstream circuitry must be matched to the nature of the encoding performed at the input. Her...

journal_title：Journal of neurophysiology

authors： Arnson HA,Holy TE

更新日期：2011-07-01 00:00:00

abstract：:This study examined whether neuronal activity in the dorsal premotor cortex (PMd) covaries with image motion or actual movement of the arm while planning a target-capturing task when the motor task is guided by an image of the moving arm. For this purpose, we trained a monkey to capture a target on a video screen with...

journal_title：Journal of neurophysiology

authors： Ochiai T,Mushiake H,Tanji J

更新日期：2002-10-01 00:00:00

abstract：:We recorded local field potentials (LFPs) and single-unit activity simultaneously in the macaque primary visual cortex (V1) and studied their responses to drifting sinusoidal gratings that were chosen to be "optimal" for the single units. Over all stimulus conditions, the LFP spectra have much greater power in the low...

journal_title：Journal of neurophysiology

authors： Henrie JA,Shapley R

更新日期：2005-07-01 00:00:00

abstract：:With each eye movement, stationary objects in the world change position on the retina, yet we perceive the world as stable. Spatial updating, or remapping, is one neural mechanism by which the brain compensates for shifts in the retinal image caused by voluntary eye movements. Remapping of a visual representation is b...

journal_title：Journal of neurophysiology

authors： Merriam EP,Genovese CR,Colby CL

更新日期：2007-02-01 00:00:00

abstract：:Hierarchical models of auditory processing often posit that optimal stimuli, i.e., those eliciting a maximal neural response, will increase in bandwidth and decrease in modulation rate as one ascends the auditory neuraxis. Here, we tested how bandwidth and modulation rate interact at several loci along the human centr...

journal_title：Journal of neurophysiology

authors： Overath T,Zhang Y,Sanes DH,Poeppel D

更新日期：2012-04-01 00:00:00

abstract：:1. Although it is generally agreed that Ca2+ couples depolarization to the release of neurotransmitters, hypertonic saline and ethanol (ETOH) evoke neurosecretion independent of extracellular Ca2+. One possible explanation is that these agents release Ca2+ from an intracellular store that then stimulates Ca(2+)-depend...

journal_title：Journal of neurophysiology

authors： Brosius DC,Hackett JT,Tuttle JB

更新日期：1992-10-01 00:00:00

abstract：:Previous studies have shown that regional slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep is modulated by prior experience and learning. Although this effect has been convincingly demonstrated for the sensorimotor domain, attempts to extend these findings to the visual system have provided mixed re...

journal_title：Journal of neurophysiology

authors： Bernardi G,Betta M,Cataldi J,Leo A,Haba-Rubio J,Heinzer R,Cirelli C,Tononi G,Pietrini P,Ricciardi E,Siclari F

更新日期：2019-06-01 00:00:00

abstract：:The rate and the total amount of Ca2+ elevation in the presynaptic terminals of bullfrog sympathetic ganglia depend on the firing frequency of the terminals. Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, was used for testing whether mitochondrial Ca2+ uptake is one of the mechanisms that ...

journal_title：Journal of neurophysiology

authors： Peng YY

更新日期：1998-07-01 00:00:00

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:Many have recently questioned whether all levels of actions understanding, from lower kinematic levels to the higher goal or intention levels of action understanding, are processed in the action observation network (a network of neurons that are active during action execution and observation). A recent study by Wurm a...

journal_title：Journal of neurophysiology

authors： Marneweck M,Vallence AM

更新日期：2016-03-01 00:00:00

abstract：:The respective roles of ventral and dorsal cortical processing streams are still under discussion in both vision and audition. We characterized neural responses in the caudal auditory belt cortex, an early dorsal stream region of the macaque. We found fast neural responses with elevated temporal precision as well as n...

journal_title：Journal of neurophysiology

authors： Kusmierek P,Rauschecker JP

更新日期：2014-04-01 00:00:00

abstract：:We studied the eye movements evoked by applying small amounts of current (2-50 microA) within the oculomotor vermis of two monkeys. We first compared the eye movements evoked by microstimulation applied either during maintained pursuit or during fixation. Smooth, pursuitlike changes in eye velocity caused by the micro...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ,Miles FA

更新日期：1998-10-01 00:00:00