CB1 modulation of temporally distinct synaptic facilitation among local circuit interneurons mediated by N-type calcium channels in CA1.

abstract：:Magnocellular red nucleus (RNm) is involved in controlling goal-directed limb movements such as reaching to grasp. We tested two hypotheses related to RNm's role in controlling reach-to-grasp movements. One hypothesis is that forelimb RNm neurons are grasp specific, and the other is that they specify the timing of met...

journal_title：Journal of neurophysiology

authors： Van Kan PL,McCurdy ML

更新日期：2002-03-01 00:00:00

abstract：:Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

journal_title：Journal of neurophysiology

authors： Gardner D,Ruff RL,White RL

更新日期：1984-01-01 00:00:00

abstract：:1. Properties of nucleus incertus (NIC) neurons projecting to the cerebellar flocculus were studied in alert cats by using chronic unit and eye movement recording and antidromic activation. Projection of these neurons onto the flocculus was verified with retrograde transport of horseradish peroxidase after injections ...

journal_title：Journal of neurophysiology

authors： Cheron G,Saussez S,Gerrits N,Godaux E

更新日期：1995-09-01 00:00:00

abstract：:Neurons in area MT, a motion-sensitive area of extrastriate cortex, respond to a step of target velocity with a transient-sustained firing pattern. The transition from a high initial firing rate to a lower sustained rate occurs over a time course of 20-80 ms and is considered a form of short-term adaptation. The prese...

journal_title：Journal of neurophysiology

authors： Priebe NJ,Churchland MM,Lisberger SG

更新日期：2002-07-01 00:00:00

abstract：:Primate head-free saccade generator implements a desired (post-VOR) eye position command by anticipating intended head motion. J. Neurophysiol. 78: 2811-2816, 1997. When we glance between objects, the brain ultimately controls gaze direction in space. However, it is currently unclear how this is allocated into separat...

journal_title：Journal of neurophysiology

authors： Crawford JD,Guitton D

更新日期：1997-11-01 00:00:00

abstract：:1. The horizontal eye movements induced by acceleration along the interaural axis were recorded from five monkeys (Macaca mulatta) by the use of the electromagnetic search-coil technique. Animals sat on a sled that was moved briefly in darkness along a linear track (bell-shaped acceleration profile: peak, 400 mm/s2; d...

journal_title：Journal of neurophysiology

authors： Schwarz U,Miles FA

更新日期：1991-09-01 00:00:00

abstract：:Few studies have analyzed activity-induced changes in EMG activity in individual human motor units. We studied the changes in human thenar motor unit EMG that accompany the potentiation of twitch force and fatigue of tetanic force. Single motor unit EMG and force were recorded in healthy subjects in response to select...

journal_title：Journal of neurophysiology

authors： Thomas CK,Johansson RS,Bigland-Ritchie B

更新日期：2006-03-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca(2+) and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have...

journal_title：Journal of neurophysiology

authors： Kleiman RJ,Tian N,Krizaj D,Hwang TN,Copenhagen DR,Reichardt LF

更新日期：2000-07-01 00:00:00

abstract：:In this study we analyzed transient voltage-activated K+ currents (IA) of projection neurons and local interneurons in the antennal lobe of the cockroach Periplaneta americana The antennal lobe is the first synaptic processing station for olfactory information in insects. Local interneurons are crucial for computing o...

journal_title：Journal of neurophysiology

authors： Paeger L,Bardos V,Kloppenburg P

更新日期：2017-05-01 00:00:00

abstract：:1. The effect of serotonin (5-HT) and forskolin on an inwardly rectifying K+ conductance (IKR) was studied using voltage-clamp techniques in several identified Aplysia neurons isolated and maintained in primary cell culture. 2. Inward rectification was observed in the current-voltage relationship of the identified neu...

journal_title：Journal of neurophysiology

authors： Lotshaw DP,Levitan IB

更新日期：1987-11-01 00:00:00

abstract：:Hyperphagia is common in diabetes and may worsen hyperglycemia and diabetic complications. The responsible mechanisms are not well understood. The hypothalamus is a key center for the control of appetite and energy homeostasis. The ventromedial nucleus (VMH) and arcuate nucleus (ARC) are two critical nuclei involved i...

journal_title：Journal of neurophysiology

authors： Li JY,Wu X,Lee A,Zhou SY,Owyang C

更新日期：2019-03-01 00:00:00

abstract：:Saccade adaptation is a mechanism that adjusts saccade landing positions if they systematically fail to reach their intended target. In the laboratory, saccades can be shortened or lengthened if the saccade target is displaced during execution of the saccade. In this study, saccades were performed from different posit...

journal_title：Journal of neurophysiology

authors： Zimmermann E

更新日期：2013-04-01 00:00:00

abstract：:Endocannabinoids are lipid derivatives that mediate paracrine and juxtacrine signaling between cells. In the hippocampal CA1 region, a retrograde endocannabinoid signal suppresses GABA release by acting on presynaptic cannabinoid receptor-1 (CB1) and can be functionally manifested as depolarization-induced suppression...

journal_title：Journal of neurophysiology

authors： Zhu PJ,Lovinger DM

更新日期：2010-02-01 00:00:00

abstract：:1. Mechanisms of depolarizing synaptic inhibition were investigated at the crayfish giant motor synapse with the use of two-electrode current- and voltage-clamp techniques. Depolarizing inhibitory postsynaptic potentials (d-IPSPs) of between 5 and 15 mV in amplitude are produced there in the motor giant motoneuron (Mo...

journal_title：Journal of neurophysiology

authors： Edwards DH

更新日期：1990-08-01 00:00:00

abstract：:Microelectrode studies in monkeys performing short-term memory tasks show the sustained elevated discharge of cortical neurons during the retention of recalled sensory information. Cortical cells that are part of memory networks are assumed to receive numerous inputs of excitatory as well as inhibitory nature and loca...

journal_title：Journal of neurophysiology

authors： Bodner M,Zhou YD,Fuster JM

更新日期：1997-04-01 00:00:00

abstract：:Neurons display a variety of complex dendritic morphologies even within the same class. We examined the relationship between dendritic arborization and the coupling between somatic and dendritic action potential (AP) initiation sites in layer 5 (L5) neocortical pyramidal neurons. Coupling was defined as the relative r...

journal_title：Journal of neurophysiology

authors： Schaefer AT,Larkum ME,Sakmann B,Roth A

更新日期：2003-06-01 00:00:00

abstract：:The medullary ventral respiratory column (VRC) of neurons is essential for respiratory motor pattern generation; however, the functional connections among these cells are not well understood. A rostral extension of the VRC, including the retrotrapezoid nucleus/parafacial region (RTN-pF), contains neurons responsive to...

journal_title：Journal of neurophysiology

authors： Ott MM,Nuding SC,Segers LS,Lindsey BG,Morris KF

更新日期：2011-06-01 00:00:00

abstract：:1. In vagotomized, paralyzed, decerebrate cats, simultaneous recordings were taken from one or more sympathetic nerves [cervical sympathetic (CS), inferior cardiac (IC), splanchnic (SP)] and from medullary neurons in vasomotor-related regions. Coherence analyses were used to ascertain the presence of sympathetic rhyth...

journal_title：Journal of neurophysiology

authors： Cohen MI,Yu Q,Huang WX

更新日期：1995-07-01 00:00:00

abstract：:Numerous developmental changes in the nervous system occur during the first several weeks of the rodent lifespan. Therefore, many characteristics of neuronal function described at the cellular level from in vitro slice experiments conducted during this early time period may not generalize to adult ages. We investigate...

journal_title：Journal of neurophysiology

authors： Paul K,Cox CL

更新日期：2013-03-01 00:00:00

abstract：:Many neurophysiological experiments involving monkeys require that the head be stabilized while the animal performs a task. Often a post is attached to the skull to accomplish this goal, using a headcap formed from dental acrylic. We describe a new headpost, developed by refinement of several prototypes, and supply an...

journal_title：Journal of neurophysiology

authors： Adams DL,Economides JR,Jocson CM,Horton JC

更新日期：2007-08-01 00:00:00

abstract：:Human functional magnetic resonance imaging (fMRI) studies, as well as lesion, drug, and single-cell recording studies in animals, suggest that the striatum plays a key role in associating sensory events with rewarding actions, both by facilitating reward processing and prediction (i.e., reinforcement learning) and by...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Seger CA

更新日期：2013-10-01 00:00:00

abstract：:Visual tracking of moving objects requires prediction to compensate for visual delays and minimize mismatches between eye and target position and velocity. In everyday life, objects often disappear behind an occluder, and prediction is required to align eye and target at reappearance. Earlier studies investigating eye...

journal_title：Journal of neurophysiology

authors： Orban de Xivry JJ,Bennett SJ,Lefèvre P,Barnes GR

更新日期：2006-01-01 00:00:00

abstract：:1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

journal_title：Journal of neurophysiology

authors： Chamberlain SC,Barlow RB Jr

更新日期：1982-08-01 00:00:00

abstract：:1. Neuronal responses to cutaneous and noncutaneous stimulation were examined in the hindlimb representation of the precentral motor cortex (MI) and the first somatosensory cortex (SI) of unanesthetized monkeys. 2. MI can be divided into two distinct parts of the basis of its afferent input. The rostral part receives ...

journal_title：Journal of neurophysiology

authors： Tanji J,Wise SP

更新日期：1981-03-01 00:00:00

abstract：:Cognitive and motor deficits associated with language and speech are seen in humans harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are thought to reside in structural abnormalities distributed across systems important for language and motor learning including the cerebral cortex, basal...

journal_title：Journal of neurophysiology

authors： Miller JE,Spiteri E,Condro MC,Dosumu-Johnson RT,Geschwind DH,White SA

更新日期：2008-10-01 00:00:00

abstract：:1. The synaptic pathways underlying tectal influence over pinna movements were studied using an acute electrophysiological approach. Under pentobarbital anesthesia, postsynaptic potentials were recorded intracellularly in antidromically identified, cat facial motoneurons following electrical stimulation of the superio...

journal_title：Journal of neurophysiology

authors： Vidal PP,May PJ,Baker R

更新日期：1988-08-01 00:00:00

abstract：:Fragile X syndrome is produced by a defect in a single X-linked gene, called Fmr1, and is characterized by abnormal dendritic spine morphologies with spines that are longer and thinner in neocortex than those from age-matched controls. Studies using Fmr1 knockout mice indicate that spine abnormalities are especially p...

journal_title：Journal of neurophysiology

authors： Desai NS,Casimiro TM,Gruber SM,Vanderklish PW

更新日期：2006-10-01 00:00:00

abstract：:1. Passive hyperpolarizing potentials (PHPs) have been recorded intracellularly from goldfish medullary neurons in the vicinity of the Mauthner cell (M-cell). They are evoked when this cell is activated antidromically by stimulation of the spinal cord, and orthodromically via the ipsilateral eighth nerve; when appropr...

journal_title：Journal of neurophysiology

authors： Korn H,Faber DS

更新日期：1975-03-01 00:00:00

abstract：:Filamentous actin (F-actin) was measured in cultured rat cerebellum granule neurons with the use of fluorescently labeled phallotoxin as a site-specific probe for F-actin, and fluorescence microscopy. The averaged apparent intensity of soma-associated F-actin-derived fluorescence (F(app)) was measured from fixed cells...

journal_title：Journal of neurophysiology

authors： Shorte SL

更新日期：1997-08-01 00:00:00

abstract：:Glutamate, the neurotransmitter, enhances rapid-eye-movement (REM) sleep when microinjected into the brain stem pedunculopontine tegmentum (PPT) of the cat and rat. Glutamate and its various receptors are normally present in the PPT cholinergic cell compartment. The aim of this study was to identify which specific rec...

journal_title：Journal of neurophysiology

authors： Datta S

更新日期：2002-04-01 00:00:00