Early postnatal plasticity in neocortex of Fmr1 knockout mice.

abstract：:Fast inhibitory synaptic transmission in the brain relies on ionotropic GABA(A) receptors (GABA(A)R). Eighteen genes code for GABA(A)R subunits, but little is known about the epsilon subunit. Our aim was to identify the synaptic transmission properties displayed by native receptors incorporating epsilon. Immunogold lo...

journal_title：Journal of neurophysiology

authors： Belujon P,Baufreton J,Grandoso L,Boué-Grabot E,Batten TF,Ugedo L,Garret M,Taupignon AI

更新日期：2009-10-01 00:00:00

abstract：:The voltage-gated K(+) channel Kv1.3 has been reported to regulate transmitter release in select central and peripheral neurons. In this study, we evaluated its role at the synapse between visceral sensory afferents and secondary neurons in the nucleus of the solitary tract (NTS). We identified mRNA and protein for Kv...

journal_title：Journal of neurophysiology

authors： Ramirez-Navarro A,Glazebrook PA,Kane-Sutton M,Padro C,Kline DD,Kunze DL

更新日期：2011-06-01 00:00:00

abstract：:Experience-dependent modification in the electrical properties of central neurons is a form of intrinsic plasticity that occurs during development and has been observed following behavioral learning. We report a novel form of intrinsic plasticity in hippocampal CA1 pyramidal neurons mediated by the KV7/KCNQ and CaV1/L...

journal_title：Journal of neurophysiology

authors： Wu WW,Chan CS,Surmeier DJ,Disterhoft JF

更新日期：2008-10-01 00:00:00

abstract：:In songbirds, the basal ganglia outflow nucleus LMAN is a cortical analog that is required for several forms of song plasticity and learning. Moreover, in adults, inactivating LMAN can reverse the initial expression of learning driven via aversive reinforcement. In the present study, we investigated how LMAN contribut...

journal_title：Journal of neurophysiology

authors： Warren TL,Tumer EC,Charlesworth JD,Brainard MS

更新日期：2011-10-01 00:00:00

abstract：:1. The functional organization of interneurons in spinal laminae III-V was studied in an isolated preparation of hamster dorsal horn with sensory innervation from an excised skin patch. Morphological details of 40 neurons were visualized by intracellular injection of horseradish peroxidase. Active and passive membrane...

journal_title：Journal of neurophysiology

authors： Schneider SP

更新日期：1992-11-01 00:00:00

abstract：:Overestimation of roll tilt in hypergravity ("G-excess" illusion) has been demonstrated, but corresponding sustained hypogravic conditions are impossible to create in ground laboratories. In this article we describe the first systematic experimental evidence that in a hypogravity analog, humans underestimate roll tilt...

journal_title：Journal of neurophysiology

authors： Galvan-Garza RC,Clark TK,Sherwood D,Diaz-Artiles A,Rosenberg M,Natapoff A,Karmali F,Oman CM,Young LR

更新日期：2018-12-01 00:00:00

abstract：:Dopamine neurons of the ventral tegmental area (VTA) signal the occurrence of a reward-predicting conditioned stimulus (CS) with a subsecond duration increase in post-CS firing rate. Important theories about reward-prediction error and reward expectancy have been informed by the substantial number of studies that have...

journal_title：Journal of neurophysiology

authors： Totah NK,Kim Y,Moghaddam B

更新日期：2013-07-01 00:00:00

abstract：:The execution of action sequences is the basis of most behavior. However, little is known about the neural foundation of visuomotor sequence execution in birds, although pigeons are a classic model animal to study sequence learning and production. Recently, we identified two structures in the pigeon brain, the nidopal...

journal_title：Journal of neurophysiology

authors： Helduser S,Cheng S,Güntürkün O

更新日期：2013-02-01 00:00:00

abstract：:Our group set out to develop a sensitive technique, capable of detecting output changes from the posterior fossa following a motor acquisition task. Transcranial magnetic stimulation (TMS) was applied over the right cerebellar cortex 5 ms in advance of test stimuli over the left cerebral motor cortex (M1), suppressing...

journal_title：Journal of neurophysiology

authors： Baarbé J,Yielder P,Daligadu J,Behbahani H,Haavik H,Murphy B

更新日期：2014-02-01 00:00:00

abstract：:This second paper of the series deals with another issue regarding sensorimotor representations in the CNS that has received much attention, namely the relative weighting of kinematic and kinetic representations. The question we address here is the contribution of muscle tension afferent information in dorsal spinocer...

journal_title：Journal of neurophysiology

authors： Bosco G,Poppele RE

更新日期：2000-05-01 00:00:00

abstract：:To probe the mechanism of visual suppression, we have raised macaques with strabismus by disinserting the medial rectus muscle in each eye at 1 mo of age. Typically, this operation produces a comitant, alternating exotropia with normal acuity in each eye. Here we describe an unusual occurrence: the development of seve...

journal_title：Journal of neurophysiology

authors： Adams DL,Economides JR,Horton JC

更新日期：2015-05-01 00:00:00

abstract：:Endocannabinoids released from the postsynaptic neuronal membrane can activate presynaptic CB1 receptors and inhibit neurotransmitter release. In hippocampal slices, depolarization of the CA1 pyramidal neurons elicits an endocannabinoid-mediated inhibition of gamma-aminobutyric acid release known as depolarization-ind...

journal_title：Journal of neurophysiology

authors： Sheinin A,Talani G,Davis MI,Lovinger DM

更新日期：2008-08-01 00:00:00

abstract：:Monocular deprivation (MD) during the critical period for the development of visual cortex causes a loss of binocular response of neurons and a shift to the open eye, a normal ocular dominance (OD) shift. However, when MD is combined with chronic inactivation of the visual cortex by muscimol, the OD distribution of th...

journal_title：Journal of neurophysiology

authors： Shimegi S,Fischer QS,Yang Y,Sato H,Daw NW

更新日期：2003-12-01 00:00:00

abstract：:We recently reported evidence indicating that selective attention is deployed to a target location in a multi-object display, when the target event (a change of one of the objects) is preceded by subliminal flicker in the gamma range. However, concerns have been raised regarding the stimuli used in this study and the ...

journal_title：Journal of neurophysiology

authors： Cheadle SW,Parton A,Müller HJ,Usher M

更新日期：2011-02-01 00:00:00

abstract：:Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

journal_title：Journal of neurophysiology

authors： Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

更新日期：2015-03-01 00:00:00

abstract：:Recent work in the anterior piriform cortex (aPCX) has demonstrated that cortical odor receptive fields are highly dynamic, showing rapid changes of both firing rate and temporal patterning within relatively few inhalations of an odor, despite relatively maintained, patterned input from olfactory bulb mitral/tufted ce...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-12-01 00:00:00

abstract：:Trimming all but two whiskers in adult rats produces a predictable change in cortical cell-evoked responses characterized by increased responsiveness to the two intact whiskers and decreased responsiveness to the trimmed whiskers. This type of synaptic plasticity in rat somatic sensory cortex, called "whisker pairing ...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Lu SM,Wiley RG,Ebner FF

更新日期：1998-06-01 00:00:00

abstract：:In the cochlear nucleus (CN) of awake mustached bats, single- and two-tone stimuli were used to examine how responses in major CN subdivisions contribute to spectrotemporal integrative features in the inferior colliculus (IC). Across CN subdivisions, the proportional representation of frequencies differed. A striking ...

journal_title：Journal of neurophysiology

authors： Marsh RA,Nataraj K,Gans D,Portfors CV,Wenstrup JJ

更新日期：2006-01-01 00:00:00

abstract：:The caudal primate prefrontal cortex (PFC) is involved in target selection and visually guided saccades through both covert attention and overt orienting eye movements. Unilateral damage to the caudal PFC often leads to decreased awareness of a contralesional target alone, referred to as "neglect," or when it is prese...

journal_title：Journal of neurophysiology

authors： Adam R,Johnston K,Everling S

更新日期：2019-08-01 00:00:00

abstract：:The dorsal nucleus of the lateral lemniscus (DNLL) receives afferent inputs from many brain stem nuclei and, in turn, is a major source of inhibitory inputs to the inferior colliculus (IC). The goal of this study was to characterize the monaural and binaural response properties of neurons in the DNLL of unanesthetized...

journal_title：Journal of neurophysiology

authors： Davis KA,Lomakin O,Pesavento MJ

更新日期：2007-09-01 00:00:00

abstract：:The group I metabotropic glutamate receptor (mGluR) subtype, mGluR1, is highly expressed on the apical dendrites of olfactory bulb mitral cells and thus may be activated by glutamate released from olfactory nerve (ON) terminals. Previous studies have shown that mGluR1 agonists directly excite mitral cells. In the pres...

journal_title：Journal of neurophysiology

authors： Ennis M,Zhu M,Heinbockel T,Hayar A

更新日期：2006-04-01 00:00:00

abstract：:A key element of walking is the coordinated interplay of multiple limbs to achieve a stable locomotor pattern that is adapted to the environment. We investigated intersegmental coordination of walking in the stick insect, Carausius morosus by examining the influence a single stepping leg has on the motoneural activity...

journal_title：Journal of neurophysiology

authors： Borgmann A,Scharstein H,Büschges A

更新日期：2007-09-01 00:00:00

abstract：:Recent work has implicated low-frequency (<20 Hz) neuronal phase information as important for both auditory (<10 Hz) and speech [theta (∼4-8 Hz)] perception. Activity on the timescale of theta corresponds linguistically to the average length of a syllable, suggesting that information within this range has consequences...

journal_title：Journal of neurophysiology

authors： Cogan GB,Poeppel D

更新日期：2011-08-01 00:00:00

abstract：:Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

journal_title：Journal of neurophysiology

authors： Gardner D,Ruff RL,White RL

更新日期：1984-01-01 00:00:00

abstract：:Generalization is a fundamental aspect of behavior, allowing for the transfer of knowledge from one context to another. The details of this transfer are thought to reveal how the brain represents what it learns. Generalization has been a central focus in studies of sensorimotor adaptation, and its pattern has been wel...

journal_title：Journal of neurophysiology

authors： McDougle SD,Bond KM,Taylor JA

更新日期：2017-07-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:The spinal network coordinating locomotion is comprised of a core of glutamate and glycine interneurons. This network is modulated by several transmitter systems including spinal GABA interneurons. The purpose of this study is to explore the contribution of GABAergic neurons to the regulation of locomotor burst freque...

journal_title：Journal of neurophysiology

authors： Schmitt DE,Hill RH,Grillner S

更新日期：2004-10-01 00:00:00

abstract：:Cats were reared in total darkness from birth until 4-5 mo of age (DR cats, n = 7) or with very brief visual experience (1 or 2 days) during an otherwise similar period of dark rearing [DR(1) cats, n = 3; DR(2) cats, n = 7]. Single-cell recordings were made in area 17 of visual cortex at the end of this rearing period...

journal_title：Journal of neurophysiology

authors： Mower GD,Christen WG

更新日期：1985-02-01 00:00:00

abstract：:Responses to rapid application of glutamic acid (Glu) and gamma-aminobutyric acid (GABA), 0.01-3 mM, were recorded by whole-cell patch clamp of cultured crab (Cardisoma carnifex) X-organ neurons. Responses peaked within 200 ms. Both Glu and GABA currents had reversal potentials that followed the Nernst Cl(-) potential...

journal_title：Journal of neurophysiology

authors： Duan S,Cooke IM

更新日期：2000-01-01 00:00:00

abstract：:1. Neurons (n = 142) were recorded with extracellular micropipettes in the parabrachial (PB) area, in the anesthetized rat, some of them being antidromically driven from the centralis nucleus of the amygdala (Ce). The spontaneous activity of these neurons was low, (10th percentile < median frequency < 90th percentile;...

journal_title：Journal of neurophysiology

authors： Bernard JF,Huang GF,Besson JM

更新日期：1994-05-01 00:00:00