Dopamine regulates distinctively the activity patterns of striatal output neurons in advanced parkinsonian primates.

abstract：:Numerous developmental changes in the nervous system occur during the first several weeks of the rodent lifespan. Therefore, many characteristics of neuronal function described at the cellular level from in vitro slice experiments conducted during this early time period may not generalize to adult ages. We investigate...

journal_title：Journal of neurophysiology

authors： Paul K,Cox CL

更新日期：2013-03-01 00:00:00

abstract：:Cervical dystonia (CD) is a movement disorder that involves involuntary turning and twisting of the neck caused by abnormal muscle contraction. Deep brain stimulation (DBS) in the globus pallidus internus (GPi) is used to treat both CD and the motor symptoms of Parkinson's disease (PD). It has been suggested that the ...

journal_title：Journal of neurophysiology

authors： Tang JK,Moro E,Mahant N,Hutchison WD,Lang AE,Lozano AM,Dostrovsky JO

更新日期：2007-08-01 00:00:00

abstract：:The progenitor cells from the anterior part of the neonatal subventricular zone, the SVZa, are unusual in that, although they undergo division, they have a neuronal phenotype. To characterize the electrophysiological properties of the SVZa precursor cells, recordings were made of potassium and sodium currents from SVZ...

journal_title：Journal of neurophysiology

authors： Stewart RR,Zigova T,Luskin MB

更新日期：1999-01-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:We examined whether presenting an odor with a positive, neutral, or negative name would influence how people perceive it. In experiment 1, 40 participants rated 15 odors for their pleasantness, intensity, and arousal. In experiment 2, 30 participants passively smelled 10 odors while their skin conductance (SC), heart ...

journal_title：Journal of neurophysiology

authors： Djordjevic J,Lundstrom JN,Clément F,Boyle JA,Pouliot S,Jones-Gotman M

更新日期：2008-01-01 00:00:00

abstract：:1. Here we study the variability in extracellular records of action potentials. Our work is motivated, in part, by the need to construct effective algorithms to classify single-unit waveforms from multiunit recordings. 2. We used microwire electrode pairs (stereotrodes) to record from primary somatosensory cortex of a...

journal_title：Journal of neurophysiology

authors： Fee MS,Mitra PP,Kleinfeld D

更新日期：1996-12-01 00:00:00

abstract：:Odor identification (OI) tests are increasingly used clinically as biomarkers for Alzheimer's disease and schizophrenia. The aim of this study was to directly compare the neuronal correlates to identified odors vs. nonidentified odors. Seventeen females with normal olfactory function underwent a functional magnetic re...

journal_title：Journal of neurophysiology

authors： Kjelvik G,Evensmoen HR,Brezova V,Håberg AK

更新日期：2012-07-01 00:00:00

abstract：:Using near-infrared spectroscopy (NIRS) and multichannel probes, we studied hemoglobin (Hb) concentration changes when single-pulse transcranial magnetic stimulation (TMS) was applied over the left hemisphere primary motor cortex (M1). Seventeen measurement probes were centered over left M1. Subjects were studied in b...

journal_title：Journal of neurophysiology

authors： Furubayashi T,Mochizuki H,Terao Y,Arai N,Hanajima R,Hamada M,Matsumoto H,Nakatani-Enomoto S,Okabe S,Yugeta A,Inomata-Terada S,Ugawa Y

更新日期：2013-03-01 00:00:00

abstract：:For human locomotion, varying environments require adjustments of the motor system. We asked whether age affects gait balance recovery adaptation, its retention over months, and the transfer of adaptation to an untrained reactive balance task. Healthy adults (26 young, 27 middle-aged, and 25 older; average ages 24, 52...

journal_title：Journal of neurophysiology

authors： König M,Epro G,Seeley J,Potthast W,Karamanidis K

更新日期：2019-11-01 00:00:00

abstract：:We investigated the postnatal development of axon sensitivity to the withdrawal of oxygen, glucose, or the combined withdrawal of oxygen + glucose in the isolated rat optic nerve (a CNS white matter tract). Removal of either oxygen or glucose for 60 min resulted in irreversible injury in optic nerves from adult rats, ...

journal_title：Journal of neurophysiology

authors： Fern R,Davis P,Waxman SG,Ransom BR

更新日期：1998-01-01 00:00:00

abstract：:Remembered object locations are stored in an eye-fixed reference frame, so that every time the eyes move, spatial representations must be updated for the arm-motor system to reflect the target's new relative position. To date, studies have not investigated how the brain updates these spatial representations during oth...

journal_title：Journal of neurophysiology

authors： Thompson AA,Henriques DY

更新日期：2008-11-01 00:00:00

abstract：:Fear conditioning involves the transmission of sensory stimuli to the amygdala from the thalamus and cortex. These input synapses are prime candidates for sites of plasticity critical to the learning in fear conditioning. Because N-methyl-D-aspartate (NMDA)-dependent mechanisms have been implicated in fear learning, w...

journal_title：Journal of neurophysiology

authors： Weisskopf MG,LeDoux JE

更新日期：1999-02-01 00:00:00

abstract：:Many neurons within prefrontal cortex exhibit a tonic discharge between visual stimulation and motor response. This delay activity may contribute to movement, memory, and vision. We studied delay activity sent from the frontal eye field (FEF) in prefrontal cortex to the superior colliculus (SC). We evaluated whether t...

journal_title：Journal of neurophysiology

authors： Sommer MA,Wurtz RH

更新日期：2001-04-01 00:00:00

abstract：:The McGurk illusion is a prominent example of audiovisual speech perception and the influence that visual stimuli can have on auditory perception. In this illusion, a visual speech stimulus influences the perception of an incongruent auditory stimulus, resulting in a fused novel percept. In this high-density electroen...

journal_title：Journal of neurophysiology

authors： Roa Romero Y,Senkowski D,Keil J

更新日期：2015-04-01 00:00:00

abstract：:1. In a search for correlated fast rhythms in recurrent laryngeal (RL) expiratory (E) activities, we performed spectral and coherence analysis on bilateral RL nerve discharges in 54 midcollicular decerebrate, paralyzed cats. 2. Inspiratory (I) RL activities showed in almost all cases high-frequency oscillations (HFO, ...

journal_title：Journal of neurophysiology

authors： Huang WX,Christakos CN,Cohen MI,He Q

更新日期：1993-11-01 00:00:00

abstract：:Experiments have been carried out on the soleus muscle and its tendon in the anesthetized cat. Measurements of isometric tension and muscle stiffness were made during contraction of whole or part of the muscle in response to stimulation of ventral root filaments. In an attempt to determine the distribution of tension ...

journal_title：Journal of neurophysiology

authors： Proske U,Morgan DL

更新日期：1984-09-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:The human visual system is remarkably sensitive to environmental regularities, which can facilitate behavioral performance when sensory events conform to past experience. The point at which prior knowledge is integrated during visual perception is unclear, particularly for incidentally learned associations. One possib...

journal_title：Journal of neurophysiology

authors： Hall MG,Mattingley JB,Dux PE

更新日期：2018-04-01 00:00:00

abstract：:The intrinsic properties of tonically firing neurons in the cochlear nucleus contribute to representing average sound intensity by favoring synaptic integration across auditory nerve inputs, reducing phase locking to fine temporal acoustic structure and enhancing envelope locking. To determine whether tonically firing...

journal_title：Journal of neurophysiology

authors： Kreeger LJ,Arshed A,MacLeod KM

更新日期：2012-11-01 00:00:00

abstract：:Earlier studies suggest that the inferior temporal (IT) cortex of the monkey plays a key role in color discrimination. Here, we examined the quantitative relationship between color judgment in monkeys and the responses of color-selective neurons in the anterior part of the IT cortex (area TE) by comparing neuronal act...

journal_title：Journal of neurophysiology

authors： Matsumora T,Koida K,Komatsu H

更新日期：2008-12-01 00:00:00

abstract：:Recently developed computational techniques have been used to reduce muscle activation patterns of high complexity to a simple synergy organization and to bring new insights to the long-standing degrees of freedom problem in motor control. We used a nonnegative factorization approach to identify muscle synergies durin...

journal_title：Journal of neurophysiology

authors： Ting LH,Macpherson JM

更新日期：2005-01-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca(2+) and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have...

journal_title：Journal of neurophysiology

authors： Kleiman RJ,Tian N,Krizaj D,Hwang TN,Copenhagen DR,Reichardt LF

更新日期：2000-07-01 00:00:00

abstract：:In addition to its well-known role in the control of saccades, the primate superior colliculus (SC) has been implicated in the processes of target choice for overt orienting movements and for covert spatial attention. We focally inactivated the SC, by muscimol injection, while monkeys selected the target of a smooth p...

journal_title：Journal of neurophysiology

authors： Nummela SU,Krauzlis RJ

更新日期：2010-09-01 00:00:00

abstract：:Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo. J. Neurophysiol. 80: 2860-2869, 1998. The spontaneous activities, evoked synaptic responses, and membrane properties of CA3 pyramidal neurons and dentate granule cells in rat hippocampus were compared...

journal_title：Journal of neurophysiology

authors： Gao TM,Howard EM,Xu ZC

更新日期：1998-12-01 00:00:00

abstract：:It has been suggested that the motor system may circumvent the difficulty of controlling many degrees of freedom in the musculoskeletal apparatus by generating motor outputs through a combination of discrete muscle synergies. How a discretely organized motor system compensates for diverse perturbations has remained el...

journal_title：Journal of neurophysiology

authors： Cheung VC,d'Avella A,Bizzi E

更新日期：2009-03-01 00:00:00

abstract：:Using extra- and intracellular recording techniques, we investigated the epileptiform activity induced by low concentrations (5 and 10 microM) of bath-applied 4-aminopyridine (4-AP) in the CA3 subfield of rat hippocampal slices. We also studied the effects of 4-AP on the excitatory and inhibitory synaptic conductance ...

journal_title：Journal of neurophysiology

authors： Rutecki PA,Lebeda FJ,Johnston D

更新日期：1987-06-01 00:00:00

abstract：:Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this h...

journal_title：Journal of neurophysiology

authors： Kohn A,Metz C,Tommerdahl MA,Whitsel BL

更新日期：2002-12-01 00:00:00

abstract：:We charted postnatal changes in the intrinsic electrophysiological properties and synaptic responses of rat intrinsic cardiac ganglion (ICG) neurons. We developed a whole-mount ganglion preparation of the excised right atrial ganglion plexus. Using intracellular recordings and nerve stimulation we tested the hypothesi...

journal_title：Journal of neurophysiology

authors： Rimmer K,Harper AA

更新日期：2006-06-01 00:00:00

abstract：:Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

journal_title：Journal of neurophysiology

authors： Gardner D,Ruff RL,White RL

更新日期：1984-01-01 00:00:00

abstract：:The horizontal angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration rotations was studied in four squirrel monkeys after unilateral labyrinthectomy. Spontaneous nystagmus was measured at the beginning and end of each testing session. During the period that animals were kept in darkness (4 d...

journal_title：Journal of neurophysiology

authors： Lasker DM,Hullar TE,Minor LB

更新日期：2000-05-01 00:00:00