Abstract:
:Saccade adaptation is a mechanism that adjusts saccade landing positions if they systematically fail to reach their intended target. In the laboratory, saccades can be shortened or lengthened if the saccade target is displaced during execution of the saccade. In this study, saccades were performed from different positions to an adapted saccade target to dissociate adaptation to a spatiotopic position in external space from a combined retinotopic and spatiotopic coding. The presentation duration of the saccade target before saccade execution was systematically varied, during adaptation and during test trials, with a delayed saccade paradigm. Spatiotopic shifts in landing positions depended on a certain preview duration of the target before saccade execution. When saccades were performed immediately to a suddenly appearing target, no spatiotopic adaptation was observed. These results suggest that a spatiotopic representation of the visual target signal builds up as a function of the duration the saccade target is visible before saccade execution. Different coordinate frames might also explain the separate adaptability of reactive and voluntary saccades. Spatiotopic effects were found only in outward adaptation but not in inward adaptation, which is consistent with the idea that outward adaptation takes place at the level of the visual target representation, whereas inward adaptation is achieved at a purely motor level.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Zimmermann Edoi
10.1152/jn.00743.2012subject
Has Abstractpub_date
2013-04-01 00:00:00pages
1815-23issue
7eissn
0022-3077issn
1522-1598pii
jn.00743.2012journal_volume
109pub_type
杂志文章abstract::Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.90909.2008
更新日期:2009-06-01 00:00:00
abstract::Complex movements are generally thought to consist of a series of simpler elements. If this is so, how does the sensorimotor system assemble the pieces? This study recorded and evaluated sequences of arm movements to various targets placed in three-dimensional (3D) space. Subjects performed sequences consisting of sin...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01062.2002
更新日期:2003-06-01 00:00:00
abstract::Eigenmannia, a genus of weakly electric fish, exhibits a specialized behavior known as the jamming avoidance response (JAR). The JAR results in a categorical difference between Eigenmannia that are in groups of conspecifics and those that are alone. Fish in groups exhibit the JAR behavior and thereby experience ongoin...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00311.2006
更新日期:2006-11-01 00:00:00
abstract::Reaching to grasp is of fundamental importance to primate motor behavior and requires coordinating hand preshaping with limb transport and grasping. We aimed to clarify the role of cerebellar output via the magnocellular red nucleus (RNm) to the control of reaching to grasp. Rubrospinal fibers originating from RNm con...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.4.1461
更新日期:2001-04-01 00:00:00
abstract::Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K+ current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K+ ions were investigated in vitro with the whole cell patch-cla...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.81.4.1749
更新日期:1999-04-01 00:00:00
abstract::In many regions of the vertebrate brain, microcircuits generate local recurrent activity that aids in the processing and encoding of incoming afferent inputs. Local recurrent activity can amplify, filter, and temporally and spatially parse out incoming input. Determining how these microcircuits function is of great in...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01046.2015
更新日期:2016-03-01 00:00:00
abstract::The spinal cord has been well established as the site of generation of the locomotor rhythm in vertebrates, but studies have suggested that the caudal hindbrain in larval fish and amphibians can also generate locomotor rhythms. Here, we investigated whether the caudal hindbrain of the adult lamprey ( Petromyzon marinu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00851.2017
更新日期:2018-05-01 00:00:00
abstract::The role of dorsal root reflexes (DRRs) in acute cutaneous neurogenic inflammation induced by intradermal injection of capsaicin (CAP) was examined in anesthetized rats. Changes in cutaneous blood flow (flare) on the plantar surface of the foot were measured using a laser Doppler flowmeter, and neurogenic edema was ex...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.82.5.2602
更新日期:1999-11-01 00:00:00
abstract::1. Intracellular recordings near the output terminals of an identified interneuron (the descending contralateral movement detector, DCMD) in the locust revealed the occurrence of depolarizing synaptic potentials. These presynaptic depolarizing potentials were evoked by spikes in both DCMDs, by auditory stimuli, and by...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1981.45.3.501
更新日期:1981-03-01 00:00:00
abstract::1. Horizontal cells were enzymatically and mechanically dissociated from the white perch (Roccus americana) retina and voltage clamped using patch electrodes. Steady-state current-voltage (I-V) relationships of solitary horizontal cells were determined by changing the membrane potential in a rampwise fashion. 2. The I...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1988.60.4.1322
更新日期:1988-10-01 00:00:00
abstract::Certain hand-held tools alter the mapping between hand motion and motion of the tool end point that must be controlled in order to perform a task. For example, when using a pool cue, the motion of the cue tip is reversed relative to the hand. Previous studies have shown that the time required to initiate a reaching mo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00157.2012
更新日期:2012-10-01 00:00:00
abstract::Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1984.51.1.1
更新日期:1984-01-01 00:00:00
abstract::The dorsal premotor area (PMd) of monkeys has been implicated in processes relating to movement preparation and movement selection. In the present study, we sought to determine whether PMd neurons that are activated during a delayed reaching task have directional responses that reflect either the target (i.e., the goa...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.77.3.1195
更新日期:1997-03-01 00:00:00
abstract::The giant barnacle, Balanus nubilus, has three simple eyes, two lateral and one median. We have studied the convergence of the receptors of these ocelli by recording from the second-order cell (I-cell) and from the receptors' terminals. The I-cell's responses to illumination of the median and lateral eyes are similar ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1986.55.5.882
更新日期:1986-05-01 00:00:00
abstract::The last few years have seen an increase in the variety of in vivo experiments used for studying cerebellar physiological mechanisms. A combination of ketamine and xylazine has become a particularly popular form of anesthesia. However, because nonanesthetized control conditions are lacking in these experiments, so far...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00057.2007
更新日期:2007-09-01 00:00:00
abstract::The effects of neuronal density on morphological and functional attributes of the evolving networks were studied in cultured dissociated hippocampal neurons. Plating at different densities affected connectivity among the neurons, such that sparse networks exhibited stronger synaptic connections between pairs of record...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00914.2009
更新日期:2010-08-01 00:00:00
abstract::Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep because loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wake- and sleep-regulatory nuclei to control behavioral states. Using survival analysis of wa...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01243.2007
更新日期:2008-06-01 00:00:00
abstract::Caenorhabditis elegans responds to chemical cues using a small number of chemosensory neurons that detect a large variety of molecules in its environment. During chemotaxis, C. elegans biases its migration in spatial chemical gradients by lengthening (/shortening) periods of forward movement when it happens to be movi...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00053.2008
更新日期:2008-05-01 00:00:00
abstract::Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00549.2012
更新日期:2013-01-01 00:00:00
abstract::We have previously demonstrated that neurons R3-14 of the Aplysia abdominal ganglia specifically express a gene encoding a 108-amino acid neuropeptide precursor. This precursor is postranslationally processed by cleavage of a signal sequence and two internal dibasic residues resulting in three peptides. The peptide pr...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1987.57.4.1201
更新日期:1987-04-01 00:00:00
abstract::Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the ef...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00535.2011
更新日期:2012-01-01 00:00:00
abstract::Long-term synaptic depression (LTD) of cerebellar parallel fiber-Purkinje cell synapses is a form of use-dependent synaptic plasticity that may be studied in cell culture. One form of LTD is induced postsynaptically through an mGlu1/Ca influx/protein kinase Cα (PKCα) cascade, and its initial expression requires phosph...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00824.2011
更新日期:2012-01-01 00:00:00
abstract::We used the framework of the uncontrolled manifold (UCM) hypothesis to explore changes in the structure of variability in multifinger force-production tasks when a secondary task was introduced. Healthy young subjects produced several levels of the total force by pressing with the four fingers of the hand on force sen...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01029.2007
更新日期:2008-02-01 00:00:00
abstract::The horizontal angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration rotations was studied in four squirrel monkeys after unilateral labyrinthectomy. Spontaneous nystagmus was measured at the beginning and end of each testing session. During the period that animals were kept in darkness (4 d...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2000.83.5.2482
更新日期:2000-05-01 00:00:00
abstract::The development of modern neuroscience tools is critical for deciphering brain circuit organization and function. An important aspect for technical development is to enhance each technique's advantages and compensate for limitations. We developed a high-precision and fast functional mapping technique in brain slices t...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00992.2009
更新日期:2010-04-01 00:00:00
abstract::Action-potential propagation into the axon terminals of olfactory receptor cells was measured with the use of voltage-sensitive dye imaging in the isolated spiny lobster brain. Conditioning shocks to the olfactory nerve, known to cause long-lasting suppression of olfactory lobe neurons, allowed the selective imaging o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.80.2.1011
更新日期:1998-08-01 00:00:00
abstract::We have investigated potential mechanisms by which exercise can promote changes in neuronal plasticity via modulation of neurotrophins. Rodents were exposed to voluntary wheel running for 3 or 7 days, and their lumbar spinal cord and soleus muscle were assessed for changes in brain-derived neurotrophic factor (BDNF), ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00152.2002
更新日期:2002-11-01 00:00:00
abstract::Rats can readily be trained to jump a gap of around 16 cm in the dark and a considerably larger gap in the light for a food reward. In the light, they use vision to estimate the distance to be jumped. In the dark, they use their vibrissae at the farthest distances. Bilateral whisker shaving or barrel field lesions red...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2000.84.4.1781
更新日期:2000-10-01 00:00:00
abstract::1. Both stretch and release of the ventral superficial muscles (VSM) in the abdomen of the hermit crab, Pagurus pollicarus, activate the VSM motoneurons in the intact animal and in the isolated abdomen. 2. This reflex was studied by recording intracellularly from muscle fibers innervated by single motoneurons during s...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.6.1904
更新日期:1993-06-01 00:00:00
abstract::Dopamine (DA) neurons and GABA neurons of the substantia nigra (SN) promote distinct functions in the control of movement and have different firing properties and action potential (AP) waveforms. APs recorded from DA and GABA neurons differed in amplitude, maximal rate of rise, and duration. In addition, the threshold...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00513.2009
更新日期:2010-06-01 00:00:00