A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis.

abstract：:In mesial temporal lobe (MTL) epilepsy, which typically involves the hippocampus (HPC), epileptiform events are enhanced during slow wave sleep (SWS). It remains unclear how and why the electroencephalographic (EEG) states that constitute SWS might predispose the HPC to this type of pathological activity. Recently our...

journal_title：Journal of neurophysiology

authors： Nazer F,Dickson CT

更新日期：2009-09-01 00:00:00

abstract：:Recording simultaneous activity of a large number of neurons in distributed neuronal networks is crucial to understand higher order brain functions. We demonstrate the in vivo performance of a recently developed electrophysiological recording system comprising a two-dimensional, multi-shank, high-density silicon probe...

journal_title：Journal of neurophysiology

authors： Fiáth R,Beregszászi P,Horváth D,Wittner L,Aarts AA,Ruther P,Neves HP,Bokor H,Acsády L,Ulbert I

更新日期：2016-11-01 00:00:00

abstract：:Swimming behavior in the marine mollusc Tritonia diomedea is episodic, consisting of a series of alternating dorsal and ventral flexions initiated by a brief sensory stimulus. The swim motor pattern is generated by a network formed of four groups of premotor interneurons: cerebral cell 2 (C2), dorsal swim interneurons...

journal_title：Journal of neurophysiology

authors： Getting PA,Dekin MS

更新日期：1985-02-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:1. Serotonergic modulation of a hyperpolarization-activated inward current, Ih, and a calcium-dependent outward current, Io(Ca), was examined in the dorsal gastric (DG) motor neuron, with the use of intracellular recording techniques in an isolated preparation of the crab stomatogastric ganglion (STG). 2. Hyperpolariz...

journal_title：Journal of neurophysiology

authors： Kiehn O,Harris-Warrick RM

更新日期：1992-08-01 00:00:00

abstract：:In big brown bats, tone-specific plastic changes [best frequency (BF) shifts] of cortical and collicular neurons can be evoked by auditory fear conditioning, repetitive acoustic stimuli or cortical electric stimulation. It has been shown that acetylcholine (ACh) plays an important role in evoking large long-term corti...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N,Gao E

更新日期：2005-08-01 00:00:00

abstract：:In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

journal_title：Journal of neurophysiology

authors： Greenberg I,Manor Y

更新日期：2005-02-01 00:00:00

abstract：:We examined whether presenting an odor with a positive, neutral, or negative name would influence how people perceive it. In experiment 1, 40 participants rated 15 odors for their pleasantness, intensity, and arousal. In experiment 2, 30 participants passively smelled 10 odors while their skin conductance (SC), heart ...

journal_title：Journal of neurophysiology

authors： Djordjevic J,Lundstrom JN,Clément F,Boyle JA,Pouliot S,Jones-Gotman M

更新日期：2008-01-01 00:00:00

abstract：:Rats can readily be trained to jump a gap of around 16 cm in the dark and a considerably larger gap in the light for a food reward. In the light, they use vision to estimate the distance to be jumped. In the dark, they use their vibrissae at the farthest distances. Bilateral whisker shaving or barrel field lesions red...

journal_title：Journal of neurophysiology

authors： Jenkinson EW,Glickstein M

更新日期：2000-10-01 00:00:00

abstract：:It is well established that locomotor patterns result from the interaction between central pattern generating networks in the nervous system, local feedback from sensory neurons about movements and forces generated in the locomotor organs, and coordinating signals from neighboring segments or appendages. This review a...

journal_title：Journal of neurophysiology

authors： Büschges A

更新日期：2005-03-01 00:00:00

abstract：:Receptive fields of neurons in somatosensory area 3b of monkeys are typically described as restricted to part of a single digit or palm pad. However, such neurons are likely involved in integrating stimulus information from across the hand. To evaluate this possibility, we recorded from area 3b neurons in anesthetized...

journal_title：Journal of neurophysiology

authors： Reed JL,Qi HX,Zhou Z,Bernard MR,Burish MJ,Bonds AB,Kaas JH

更新日期：2010-04-01 00:00:00

abstract：:The nucleus gracilis (NG) receives an abundance of visceral input from various abdominal organs and is proposed to play an important role in visceral pain processing. The purpose of this study was to investigate the necessity of the NG for colorectal input into the ventral posterolateral (VPL) nucleus of the thalamus....

journal_title：Journal of neurophysiology

authors： Al-Chaer ED,Westlund KN,Willis WD

更新日期：1997-07-01 00:00:00

abstract：:Following stepping in-place on the surface of a rotating circular treadmill, a subject attempting to step in-place or walk in a straight line across the floor without vision will rotate relative to space. This adaptation, termed podokinetic after-rotation (PKAR), transfers to backward walking following forward walking...

journal_title：Journal of neurophysiology

authors： Earhart GM,Melvill Jones G,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2002-02-01 00:00:00

abstract：:Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperatu...

journal_title：Journal of neurophysiology

authors： Smotherman MS,Narins PM

更新日期：1998-01-01 00:00:00

abstract：:1. Rat dorsal root ganglion (DRG) cell bodies were screened according to action potential (AP) duration, capsaicin sensitivity, expression of IH, IA, and N-, L-, and T-type Ca2+ channel currents. AP duration was measured at half of total amplitude at a membrane potential of -60 mV. Sensitivity to capsaicin was defined...

journal_title：Journal of neurophysiology

authors： Cardenas CG,Del Mar LP,Scroggs RS

更新日期：1995-11-01 00:00:00

abstract：:Self-motion generates patterns of optic flow on the retina. Neurons in the dorsal part of the medial superior temporal area (MSTd) are selective for these optic flow patterns. It has been shown that neurons in this area that are selective for expanding optic flow fields are involved in heading judgments. We wondered h...

journal_title：Journal of neurophysiology

authors： Xu H,Wallisch P,Bradley DC

更新日期：2014-06-01 00:00:00

abstract：:Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

journal_title：Journal of neurophysiology

authors： Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

更新日期：2015-03-01 00:00:00

abstract：:Across the entire human body, postural tone might play its most critical role in the body's axis because the axis joins the four limbs and head into a single functioning unit during complex motor tasks as well as in static postures. Although postural tone is commonly viewed as low-level, tonic motor activity, we hypot...

journal_title：Journal of neurophysiology

authors： Gurfinkel V,Cacciatore TW,Cordo P,Horak F,Nutt J,Skoss R

更新日期：2006-11-01 00:00:00

abstract：:Cognitive and motor deficits associated with language and speech are seen in humans harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are thought to reside in structural abnormalities distributed across systems important for language and motor learning including the cerebral cortex, basal...

journal_title：Journal of neurophysiology

authors： Miller JE,Spiteri E,Condro MC,Dosumu-Johnson RT,Geschwind DH,White SA

更新日期：2008-10-01 00:00:00

abstract：:It has been suggested that the motor system may circumvent the difficulty of controlling many degrees of freedom in the musculoskeletal apparatus by generating motor outputs through a combination of discrete muscle synergies. How a discretely organized motor system compensates for diverse perturbations has remained el...

journal_title：Journal of neurophysiology

authors： Cheung VC,d'Avella A,Bizzi E

更新日期：2009-03-01 00:00:00

abstract：:1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...

journal_title：Journal of neurophysiology

authors： Golomb D,Wang XJ,Rinzel J

更新日期：1996-02-01 00:00:00

abstract：:Previous studies have shown that regional slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep is modulated by prior experience and learning. Although this effect has been convincingly demonstrated for the sensorimotor domain, attempts to extend these findings to the visual system have provided mixed re...

journal_title：Journal of neurophysiology

authors： Bernardi G,Betta M,Cataldi J,Leo A,Haba-Rubio J,Heinzer R,Cirelli C,Tononi G,Pietrini P,Ricciardi E,Siclari F

更新日期：2019-06-01 00:00:00

abstract：:Control of the spatial orientation of the hand is an important component of reaching and grasping movements. We studied the contribution of vision and proprioception to the perception and control of hand orientation in orientation-matching and letter-posting tasks. In the orientation-matching task, subjects aligned a ...

journal_title：Journal of neurophysiology

authors： Gosselin-Kessiby N,Messier J,Kalaska JF

更新日期：2008-04-01 00:00:00

abstract：:Serotonin [5-hydroxytryptamine (5-HT)] is a conspicuous neuromodulator of sensory-motor networks that affects a variety of neurons at different levels of the network hierarchy. Because of its many possible targets, it has been difficult to obtain a comprehensive picture of how 5-HT achieves its final modulatory output...

journal_title：Journal of neurophysiology

authors： Calviño MA,Iscla IR,Szczupak L

更新日期：2005-05-01 00:00:00

abstract：:1. Receptive fields (RFs) of neurons in the primary somatosensory (SI) cortex were defined before, during, and after electrical stimulation of myelinated fibers in the dorsal cutaneous branch of the ulnar nerve in adult pentobarbital sodium-anesthetized cats. 2. This stimulation resulted in an approximately threefold ...

journal_title：Journal of neurophysiology

authors： Recanzone GH,Allard TT,Jenkins WM,Merzenich MM

更新日期：1990-05-01 00:00:00

abstract：:Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

journal_title：Journal of neurophysiology

authors： Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

更新日期：2019-05-01 00:00:00

abstract：:The CNS controls reproduction through pulsatile secretion of gonadotropin-releasing hormone (GnRH). Episodic increases in the firing rate of unidentified hypothalamic neurons have been associated with downstream markers of GnRH secretion. Whether this episodic electrical activity is intrinsic to GnRH neurons, intrinsi...

journal_title：Journal of neurophysiology

authors： Nunemaker CS,DeFazio RA,Geusz ME,Herzog ED,Pitts GR,Moenter SM

更新日期：2001-07-01 00:00:00

abstract：:A quantitative analysis of activity-related calcium dynamics was performed in motoneurons of the nucleus hypoglossus in the brain stem slice preparation from mouse by simultaneous patch-clamp and microfluorometric calcium measurements. Motoneurons were analyzed under in vitro conditions that kept them in a functionall...

journal_title：Journal of neurophysiology

authors： Lips MB,Keller BU

更新日期：1999-12-01 00:00:00

abstract：:The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...

journal_title：Journal of neurophysiology

authors： Ollerenshaw DR,Bari BA,Millard DC,Orr LE,Wang Q,Stanley GB

更新日期：2012-07-01 00:00:00

abstract：:1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...

journal_title：Journal of neurophysiology

authors： Behrends JC,ten Bruggencate G

更新日期：1993-02-01 00:00:00