A rose by any other name: would it smell as sweet?

abstract：:1. Responses to pure tones were recorded from single neurons in the anteroventral cochlear nucleus (AVCN) in kittens ranging in age from 4 to 45 days. Different response properties mature at different times after birth. 2. The shapes of response areas of AVCN neurons after the 1st postnatal week resemble those recorde...

journal_title：Journal of neurophysiology

authors： Brugge JF,Javel E,Kitzes LM

更新日期：1978-11-01 00:00:00

abstract：:In humans with temporal lobe epilepsy and kainate-treated rats, the mossy fibers of the dentate granule cells send collateral axons into the inner molecular layer. Prior investigations on kainate-treated rats demonstrated that abnormal hilar-evoked events can occasionally be observed in slices with mossy fiber sprouti...

journal_title：Journal of neurophysiology

authors： Patrylo PR,Dudek FE

更新日期：1998-01-01 00:00:00

abstract：:The neuromodulator acetylcholine (ACh) shapes neocortical function during sensory perception, motor control, arousal, attention, learning, and memory. Here we investigate the mechanisms by which ACh affects neocortical pyramidal neurons in adult mice. Stimulation of cholinergic axons activated muscarinic and nicotinic...

journal_title：Journal of neurophysiology

authors： Hedrick T,Waters J

更新日期：2015-04-01 00:00:00

abstract：:We hypothesized that epilepsy affects the activity of the autonomic nervous system even in the absence of seizures, which should manifest as differences in heart rate variability (HRV) and cardiac cycle. To test this hypothesis, we investigated ECG traces of 91 children and adolescents with generalized epilepsy and 25...

journal_title：Journal of neurophysiology

authors： Sivakumar SS,Namath AG,Tuxhorn IE,Lewis SJ,Galán RF

更新日期：2016-04-01 00:00:00

abstract：:1. The graded, synaptic potentials of first-order visual interneurons (lamina monopolar cells) were examined with intracellular recordings. The spatiotemporal properties were characterized with drifting sine wave gratings and annuli. 2. Annulus-elicited inhibition is maximal for annulus-test pulse intervals of approxi...

journal_title：Journal of neurophysiology

authors： Glantz RM,Bartels A

更新日期：1994-06-01 00:00:00

abstract：:Information about the position of an object that is held in both hands, such as a golf club or a tennis racquet, is transmitted to the human central nervous system from peripheral sensors in both left and right arms. How does the brain combine these two sources of information? Using a robot to move participant's passi...

journal_title：Journal of neurophysiology

authors： Wong JD,Wilson ET,Kistemaker DA,Gribble PL

更新日期：2014-03-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:The contributions of the hyperpolarization-activated current, I(h), to generation of rhythmic activities are well described for various central neurons, particularly in thalamocortical circuits. In the present study, we investigated effects of a general anesthetic, propofol, on native I(h) in neurons of thalamus and c...

journal_title：Journal of neurophysiology

authors： Chen X,Shu S,Bayliss DA

更新日期：2005-12-01 00:00:00

abstract：:The horizontal cell is a second-order retinal neuron that is depolarized in the dark and responds to light with graded potential changes. In such a nonspiking neuron, not only the voltage-gated ionic conductances but also Ca(2+) regulation mechanisms, e.g., the Na(+)/Ca(2+) exchange and the Ca(2+) pump, are considered...

journal_title：Journal of neurophysiology

authors： Hayashida Y,Yagi T

更新日期：2002-01-01 00:00:00

abstract：:Somatic sensory neurons of the dorsal root ganglia are necessary for a large part of our mechanosensory experience. However, we only have a good knowledge of the molecules required for mechanotransduction in simple invertebrates such as the nematode Caenorhabiditis elegans. In C. elegans, a number of so-called mec gen...

journal_title：Journal of neurophysiology

authors： Martinez-Salgado C,Benckendorff AG,Chiang LY,Wang R,Milenkovic N,Wetzel C,Hu J,Stucky CL,Parra MG,Mohandas N,Lewin GR

更新日期：2007-12-01 00:00:00

abstract：:Squirrel monkeys were trained using newly developed visual-vestibular mismatch paradigms to test the asymmetrical simultaneous induction of vertical vestibuloocular reflex (VOR) gain changes in opposite directions (high and low) either in the upward and downward directions or in response to high- and low-frequency sti...

journal_title：Journal of neurophysiology

authors： Hirata Y,Lockard JM,Highstein SM

更新日期：2002-12-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:The increasing use of transgenic mice for the study of pain mechanisms necessitates comprehensive understanding of the murine somatosensory system. Using an in vivo mouse preparation, we studied response properties of tibial nerve afferent fibers innervating glabrous skin. Recordings were obtained from 225 fibers iden...

journal_title：Journal of neurophysiology

authors： Cain DM,Khasabov SG,Simone DA

更新日期：2001-04-01 00:00:00

abstract：:During object manipulation, grip force is coordinated with load force, which is primarily determined by object kinematics. Proximal arm kinematics may affect grip force control, as proximal segment motion could affect control of distal hand muscles via biomechanical and/or neural pathways. The aim of this study was to...

journal_title：Journal of neurophysiology

authors： Vermillion BC,Lum PS,Lee SW

更新日期：2015-10-01 00:00:00

abstract：:The plant-derived insecticides have introduced a new concept in insecticide research. In response to insect attacks, some plants can release volatile sulfur compounds such as dimethyl disulfide (DMDS) in the atmosphere, which are lethal for the generalist insects. We demonstrate that DMDS induced an uncommon complex n...

journal_title：Journal of neurophysiology

authors： Dugravot S,Grolleau F,Macherel D,Rochetaing A,Hue B,Stankiewicz M,Huignard J,Lapied B

更新日期：2003-07-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by profound deficits in memory and cognitive function. Neuropathological hallmarks of the disease include a loss of basal forebrain cholinergic neurons and the deposition of beta-amyloid peptide (Abeta) in neuritic plaques. At a cellul...

journal_title：Journal of neurophysiology

authors： Fu W,Jhamandas JH

更新日期：2003-11-01 00:00:00

abstract：:In the absence of any obvious input, sensory neurons and interneurons can display resting or spontaneous activity. This is often regarded as noise and removed through trial averaging, although it may reflect history-dependent modulation of tuning or fidelity and, thus, be of functional relevance to downstream interneu...

journal_title：Journal of neurophysiology

authors： Lepreux G,Haupt SS,Dürr V

更新日期：2019-12-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrat...

journal_title：Journal of neurophysiology

authors： Defazio T,Hablitz JJ

更新日期：1998-10-01 00:00:00

abstract：:Motor behavior often occurs in environments with multiple goal options that can vary during the ongoing action. We explored this situation by requiring subjects to select between different target options during an ongoing reach. During split trials the original target was replaced with a left and a right flanking targ...

journal_title：Journal of neurophysiology

authors： Kurtzer IL,Muraoka T,Singh T,Prasad M,Chauhan R,Adhami E

更新日期：2020-10-01 00:00:00

abstract：:Dual whole-cell patch clamp recordings from the soma and dendrites of CA1 pyramidal neurons located in hippocampal slices of adult rats were used to examine the potential mechanisms of phase precession. To mimic phasic synaptic input, 5-Hz sine wave current injections were simultaneously delivered both to the soma and...

journal_title：Journal of neurophysiology

authors： Magee JC

更新日期：2001-07-01 00:00:00

abstract：:The effects of deep brain stimulation (DBS) on balance in people with Parkinson's disease (PD) are not well established. This study examined whether DBS randomized to the subthalamic nucleus (STN; n = 11) or globus pallidus interna (GPi; n = 10) improved compensatory stepping to recover balance after a perturbation. T...

journal_title：Journal of neurophysiology

authors： St George RJ,Carlson-Kuhta P,King LA,Burchiel KJ,Horak FB

更新日期：2015-09-01 00:00:00

abstract：:Our objective was to assess the mechanical changes associated with spasticity in elbow muscles of chronic hemiparetic stroke survivors and to compare these changes with those recorded in the ankle muscles of a similar cohort. We first characterized elbow dynamic stiffness by applying pseudorandom binary positional per...

journal_title：Journal of neurophysiology

authors： Mirbagheri MM,Settle K,Harvey R,Rymer WZ

更新日期：2007-08-01 00:00:00

abstract：:Whole cell patch-clamp recordings revealed a subpopulation (16%, n = 18/112) of rat median preoptic nucleus (MnPO) neurons responded to bath-applied angiotensin II (Ang II; 100 nM to 5 microM; 30-90 s) with a prolonged TTX-resistant membrane depolarization and rhythmic bursting activity. At rest, cells characteristica...

journal_title：Journal of neurophysiology

authors： Spanswick D,Renaud LP

更新日期：2005-04-01 00:00:00

abstract：:Although previous research with human and nonhuman primates has examined the neural correlates of performance monitoring, discrepancies in methodology have limited our ability to make cross-species generalizations. One major obstacle arises from the use of different behavioral responses and tasks across different prim...

journal_title：Journal of neurophysiology

authors： Reinhart RM,Carlisle NB,Kang MS,Woodman GF

更新日期：2012-05-01 00:00:00

abstract：:Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

journal_title：Journal of neurophysiology

authors： Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

更新日期：2015-03-01 00:00:00

abstract：:The intrinsic properties of tonically firing neurons in the cochlear nucleus contribute to representing average sound intensity by favoring synaptic integration across auditory nerve inputs, reducing phase locking to fine temporal acoustic structure and enhancing envelope locking. To determine whether tonically firing...

journal_title：Journal of neurophysiology

authors： Kreeger LJ,Arshed A,MacLeod KM

更新日期：2012-11-01 00:00:00

abstract：:In this article, we review a recent paper by Stevenson et al. (J Neurosci 34: 691-697, 2014). This paper illustrates the need to present different forms of stimuli in order to characterize the perceptual abilities of people with autism spectrum disorder (ASD). Furthermore, we will discuss their behavioral results and ...

journal_title：Journal of neurophysiology

authors： Chan JS,Naumer MJ

更新日期：2014-12-01 00:00:00

abstract：:Human functional magnetic resonance imaging (fMRI) studies, as well as lesion, drug, and single-cell recording studies in animals, suggest that the striatum plays a key role in associating sensory events with rewarding actions, both by facilitating reward processing and prediction (i.e., reinforcement learning) and by...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Seger CA

更新日期：2013-10-01 00:00:00