Signs of functional maturation of peripheral auditory system in discharge patterns of neurons in anteroventral cochlear nucleus of kitten.

abstract：:The inferior colliculus (IC) is highly modulated by descending projections from higher auditory and nonauditory centers. Traditionally, corticofugal fibers were believed to project mainly to the extralemniscal IC regions. However, there is some anatomical evidence suggesting that a substantial number of fibers from th...

journal_title：Journal of neurophysiology

authors： Lim HH,Anderson DJ

更新日期：2007-02-01 00:00:00

abstract：:The role of the nitric oxide (NO)-cGMP signaling cascade in modulation of peripheral nociception is controversial. Although behavioral studies have suggested both pro- and anti-nociceptive effects, little is known about the direct action of this signaling cascade on primary afferent nociceptive neurons that mediate th...

journal_title：Journal of neurophysiology

authors： Levy D,Strassman AM

更新日期：2004-08-01 00:00:00

abstract：:Working memory (WM) performance is impaired by the presence of external interference. Accordingly, more efficient processing of intervening stimuli with practice may lead to enhanced WM performance. To explore the role of practice on the impact that interference has on WM performance, we studied young adults with elec...

journal_title：Journal of neurophysiology

authors： Berry AS,Zanto TP,Rutman AM,Clapp WC,Gazzaley A

更新日期：2009-09-01 00:00:00

abstract：:Although understanding the processing of natural sounds is an important goal in auditory neuroscience, relatively little is known about the neural coding of these sounds. Recently we demonstrated that the spectral temporal receptive field (STRF), a description of the stimulus-response function of auditory neurons, cou...

journal_title：Journal of neurophysiology

authors： Sen K,Theunissen FE,Doupe AJ

更新日期：2001-09-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:Magnocellular red nucleus (RNm) is involved in controlling goal-directed limb movements such as reaching to grasp. We tested two hypotheses related to RNm's role in controlling reach-to-grasp movements. One hypothesis is that forelimb RNm neurons are grasp specific, and the other is that they specify the timing of met...

journal_title：Journal of neurophysiology

authors： Van Kan PL,McCurdy ML

更新日期：2002-03-01 00:00:00

abstract：:In layer 2/3 of neocortex, brief trains of action potentials in pyramidal neurons (PNs) induce the mobilization of endogenous cannabinoids (eCBs), resulting in a depression of GABA release from the terminals of inhibitory interneurons (INs). This depolarization-induced suppression of inhibition (DSI) is mediated by ac...

journal_title：Journal of neurophysiology

authors： Lemtiri-Chlieh F,Levine ES

更新日期：2007-11-01 00:00:00

abstract：:With experience, an object can become behaviorally relevant and thereby quickly attract our interest when presented in a visual scene. A likely site of these learning effects is anterior inferior temporal (aIT) cortex, where neurons are thought to participate in the filtering of irrelevant information out of complex v...

journal_title：Journal of neurophysiology

authors： Jagadeesh B,Chelazzi L,Mishkin M,Desimone R

更新日期：2001-07-01 00:00:00

abstract：:1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, par...

journal_title：Journal of neurophysiology

authors： Mackel R,Miyashita E

更新日期：1993-05-01 00:00:00

abstract：:1. Long-term depression (LTD) is an activity-dependent reduction in the strength of synaptic transmission that can persist for hours. It is a neural model for processes underlying learning and memory, such as extinction and forgetting. LTD of excitatory postsynaptic potentials (EPSPs) in cells of the CA1 region of hip...

journal_title：Journal of neurophysiology

authors： Christofi G,Nowicky AV,Bolsover SR,Bindman LJ

更新日期：1993-01-01 00:00:00

abstract：:High-frequency burstlike electrical conditioning stimulation (HFS) applied to human skin induces an increase in mechanical pinprick sensitivity of the surrounding unconditioned skin (a phenomenon known as secondary hyperalgesia). The present study assessed the effect of frequency of conditioning stimulation on the dev...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Gousset S,Bouvy J,Stouffs A,Lebrun L,van Neerven SGA,Mouraux A

更新日期：2019-09-01 00:00:00

abstract：:The normal development and the capacity to calibrate gaze-stabilizing systems may depend on normal vision during infancy. At the end of 1 yr of dark rearing, cats have gaze-stabilizing deficits similar to that of the newborn human infant including decreased monocular optokinetic nystagmus (OKN) in the nasal to tempora...

journal_title：Journal of neurophysiology

authors： Tusa RJ,Mustari MJ,Burrows AF,Fuchs AF

更新日期：2001-08-01 00:00:00

abstract：:Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrat...

journal_title：Journal of neurophysiology

authors： Defazio T,Hablitz JJ

更新日期：1998-10-01 00:00:00

abstract：:The characteristics of the primary afferent depolarization (PAD) of Ia- and Ib-fibers generated by segmental and descending inputs have been analyzed in the spinal cord of anesthetized cats. The PAD was inferred from the changes produced by conditioning inputs on the intraspinal stimulus current required to produce a ...

journal_title：Journal of neurophysiology

authors： Rudomin P,Solodkin M,Jiménez I

更新日期：1986-10-01 00:00:00

abstract：:Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction du...

journal_title：Journal of neurophysiology

authors： Bilaloglu S,Lu Y,Geller D,Rizzo JR,Aluru V,Gardner EP,Raghavan P

更新日期：2016-03-01 00:00:00

abstract：:1. A method for adapting a standard stereotaxic frame for use with neonatal rats as young as postnatal day 1 (PD 1) was devised, and single-unit extracellular recordings were obtained from neurons in the locus ceruleus (LC) in urethan-anesthetized rats during different stages in development from PD 1 to PD 34. 2. The ...

journal_title：Journal of neurophysiology

authors： Nakamura S,Kimura F,Sakaguchi T

更新日期：1987-09-01 00:00:00

abstract：:The horizontal angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration rotations was studied in four squirrel monkeys after unilateral labyrinthectomy. Spontaneous nystagmus was measured at the beginning and end of each testing session. During the period that animals were kept in darkness (4 d...

journal_title：Journal of neurophysiology

authors： Lasker DM,Hullar TE,Minor LB

更新日期：2000-05-01 00:00:00

abstract：:We investigated a visuomotor mechanism contributing to reach correction: the manual following response (MFR), which is a quick response to background visual motion that frequently occurs as a reafference when the body moves. Although several visual specificities of the MFR have been elucidated, the functional and comp...

journal_title：Journal of neurophysiology

authors： Abekawa N,Gomi H

更新日期：2010-05-01 00:00:00

abstract：:Action potential initiation and conduction along peripheral axons is a dynamic process that displays pronounced activity dependence. In patients with neuropathic pain, differences in the modulation of axonal conduction velocity by activity suggest that this property may provide insight into some of the pathomechanisms...

journal_title：Journal of neurophysiology

authors： Tigerholm J,Petersson ME,Obreja O,Lampert A,Carr R,Schmelz M,Fransén E

更新日期：2014-05-01 00:00:00

abstract：:Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons. Seventy-eight of 82 DRG neurons exposed to 3-s ramps of increasing temperature to 48 degrees C exhibited an i...

journal_title：Journal of neurophysiology

authors： Kuffler DP,Lyfenko A,Vyklický L,Vlachová V

更新日期：2002-10-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:We used positron emission tomography to study motor learning by trial and error. Subjects learned sequences of eight finger movements. Tones generated by a computer told the subjects whether any particular move was correct or incorrect. A control condition was used in which the subjects generated moves, but there was ...

journal_title：Journal of neurophysiology

authors： Jueptner M,Frith CD,Brooks DJ,Frackowiak RS,Passingham RE

更新日期：1997-03-01 00:00:00

abstract：:Rats typically employ 4- to 12-Hz "whisking" movements of their vibrissae during tactile exploration. The intentional sampling of signals in this frequency range suggests that neural processing of tactile information may be differentially engaged in this bandwidth. We examined action potential responses in rat primary...

journal_title：Journal of neurophysiology

authors： Garabedian CE,Jones SR,Merzenich MM,Dale A,Moore CI

更新日期：2003-09-01 00:00:00

abstract：:1. Mouse hippocampal neurons in dissociated culture were grown at low density on previously plated hippocampal glial cell cultures and voltage clamped using the tight seal whole-cell patch-clamp technique. Flow pipes were used to rapidly exchange the extracellular solution, and to apply N-methyl-D-aspartic acid (NMDA)...

journal_title：Journal of neurophysiology

authors： Mayer ML,Westbrook GL,Vyklický L Jr

更新日期：1988-08-01 00:00:00

abstract：:The fastigial oculomotor region is the output by which the medioposterior cerebellum influences the generation of saccades. Recent inactivation studies reported observations suggesting an involvement in their dynamics (velocity and duration). In this work, we tested this hypothesis in the head-restrained monkey with t...

journal_title：Journal of neurophysiology

authors： Quinet J,Goffart L

更新日期：2015-05-01 00:00:00

abstract：:1. "Unmasking" of weak synaptic connections has been suggested as a mechanism for the early changes in cortical topographic maps that follow alterations of sensory activity. For such a mechanism to operate, convergent sensory inputs must already exist in the normal cortex. 2. We tested for topographic and cross-modali...

journal_title：Journal of neurophysiology

authors： Smits E,Gordon DC,Witte S,Rasmusson DD,Zarzecki P

更新日期：1991-09-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:Electrical transmission is a dynamically regulated form of communication and key to synchronizing neuronal activity. The bag cell neurons of Aplysia are a group of electrically coupled neuroendocrine cells that initiate ovulation by secreting egg-laying hormone during a prolonged period of synchronous firing called th...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Standage D,Groten CJ,Blohm G,Magoski NS

更新日期：2015-02-01 00:00:00

abstract：:1. The goal of this study was to compare the relative effectiveness of intrinsic inhibitory synaptic inputs in different layers of the cat motor cortex. Postsynaptic potentials (PSPs) were evoked in neurons located in the superficial (layer II-III) or deep layers (layer V) by local extracellular stimulation in vitro. ...

journal_title：Journal of neurophysiology

authors： van Brederode JF,Spain WJ

更新日期：1995-09-01 00:00:00

abstract：:1. The effects of dopamine on the slow Ca(2+)-dependent K+ current (IAHP; AHP, afterhyperpolarization) and spike frequency adaptation were studied by whole cell voltage-clamp and sharp microelectrode current-clamp recordings in rat CA1 pyramidal neurons in rat hippocampal slices. 2. Dopamine suppressed IAHP in a dose-...

journal_title：Journal of neurophysiology

authors： Pedarzani P,Storm JF

更新日期：1995-12-01 00:00:00