Response properties of neurons in primary somatosensory cortex of owl monkeys reflect widespread spatiotemporal integration.

abstract：:1. Although it is generally agreed that Ca2+ couples depolarization to the release of neurotransmitters, hypertonic saline and ethanol (ETOH) evoke neurosecretion independent of extracellular Ca2+. One possible explanation is that these agents release Ca2+ from an intracellular store that then stimulates Ca(2+)-depend...

journal_title：Journal of neurophysiology

authors： Brosius DC,Hackett JT,Tuttle JB

更新日期：1992-10-01 00:00:00

abstract：:If a laterally displacing prism is placed in front of one eye of a person or monkey with the other eye occluded, they initially will point to one side of a target that is located directly in front of them. Normally, people and monkeys adapt easily to the displaced vision and correct their aim after a few trials. If th...

journal_title：Journal of neurophysiology

authors： Baizer JS,Kralj-Hans I,Glickstein M

更新日期：1999-04-01 00:00:00

abstract：:Nitric oxide (NO) has been recognized as an atypical neuronal messenger affecting synaptic transmission, but its cellular source has remained unresolved as the neuronal NO synthase isoform (nNOS) in brain areas such as the neocortex is expressed only by a small subset of inhibitory neurons. The involvement of the glia...

journal_title：Journal of neurophysiology

authors： Buskila Y,Amitai Y

更新日期：2010-03-01 00:00:00

abstract：:An initial overload of intracellular Ca2+ plays a critical role in the delayed death of hippocampal CA1 neurons that die a few days after transient ischemia. Without direct evidence, the prevailing hypothesis has been that Ca2+ overload may recur until cell death. Here, we report the first measurements of intracellula...

journal_title：Journal of neurophysiology

authors： Connor JA,Razani-Boroujerdi S,Greenwood AC,Cormier RJ,Petrozzino JJ,Lin RC

更新日期：1999-01-01 00:00:00

abstract：:Monocular deprivation (MD) during the critical period for the development of visual cortex causes a loss of binocular response of neurons and a shift to the open eye, a normal ocular dominance (OD) shift. However, when MD is combined with chronic inactivation of the visual cortex by muscimol, the OD distribution of th...

journal_title：Journal of neurophysiology

authors： Shimegi S,Fischer QS,Yang Y,Sato H,Daw NW

更新日期：2003-12-01 00:00:00

abstract：:1. Here we study the variability in extracellular records of action potentials. Our work is motivated, in part, by the need to construct effective algorithms to classify single-unit waveforms from multiunit recordings. 2. We used microwire electrode pairs (stereotrodes) to record from primary somatosensory cortex of a...

journal_title：Journal of neurophysiology

authors： Fee MS,Mitra PP,Kleinfeld D

更新日期：1996-12-01 00:00:00

abstract：:Although species-specific differences in ion channel properties are well-documented, little has been known about the properties of the human Nav1.8 channel, an important contributor to pain signaling. Here we show, using techniques that include voltage clamp, current clamp, and dynamic clamp in dorsal root ganglion (D...

journal_title：Journal of neurophysiology

authors： Han C,Estacion M,Huang J,Vasylyev D,Zhao P,Dib-Hajj SD,Waxman SG

更新日期：2015-05-01 00:00:00

abstract：:We have used a computer-based mathematical model of alpha-motoneurons and of group Ia synaptic input to them, based on anatomical and electrophysiological data from the cat spinal cord, in order to examine the effects of variations in neuron size and input resistance and of conductance magnitude and duration on the ge...

journal_title：Journal of neurophysiology

authors： Lev-Tov A,Miller JP,Burke RE,Rall W

更新日期：1983-08-01 00:00:00

abstract：:An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded...

journal_title：Journal of neurophysiology

authors： Compte A,Constantinidis C,Tegner J,Raghavachari S,Chafee MV,Goldman-Rakic PS,Wang XJ

更新日期：2003-11-01 00:00:00

abstract：:Because smooth-pursuit eye movements (SPEM) can be executed only in the presence of a moving target, it has been difficult to attribute the neuronal activity observed during the execution of these eye movements to either sensory processing or to motor preparation or execution. Previously, we showed that rhesus monkeys...

journal_title：Journal of neurophysiology

authors： Ilg UJ,Thier P

更新日期：2003-09-01 00:00:00

abstract：:In a recent study, Wang et al. (J Neurophysiol 113: 1989-2001, 2015) used a precision grip force control task to unveil the contribution of feedforward and feedback mechanisms to sensorimotor dysfunction in autism spectrum disorder (ASD). Impairment of both motor control mechanisms was observed, along with significant...

journal_title：Journal of neurophysiology

authors： Parma V,de Marchena AB

更新日期：2016-03-01 00:00:00

abstract：:In the present study, we sought to unravel how exploratory movements affect length perception of rods that are held in and wielded by hand. We manipulated the mechanical rod properties--mass (m), first moment of mass distribution (M), major principal moment of inertia (I(1))--individually, allowing us to assess the re...

journal_title：Journal of neurophysiology

authors： Debats NB,van de Langenberg RW,Kingma I,Smeets JB,Beek PJ

更新日期：2010-11-01 00:00:00

abstract：:The forebrain plays an important role in many aspects of sound localization behavior. Yet, the forebrain pathway that processes auditory spatial information is not known for any species. Using standard anatomic labeling techniques, we used a "top-down" approach to trace the flow of auditory spatial information from an...

journal_title：Journal of neurophysiology

authors： Cohen YE,Miller GL,Knudsen EI

更新日期：1998-02-01 00:00:00

abstract：:The generation of a behaviorally relevant cue to the speed of objects around us is critical to our ability to navigate safely within our environment. However, our perception of speed is often distorted by prevailing conditions. For instance, as luminance is reduced, our perception of the speed of fast-moving patterns ...

journal_title：Journal of neurophysiology

authors： Hammett ST,Smith AT,Wall MB,Larsson J

更新日期：2013-08-01 00:00:00

abstract：:Spinothalamic (ST) neurons in the C8-T5 segments of the spinal cord were examined for responses to electrical stimulation of the left thoracic vagus nerve (LTV). Seventy-one ST neurons were studied in 39 anesthetized monkeys (Macaca fascicularis). Each neuron could be excited by manipulation of its somatic field and b...

journal_title：Journal of neurophysiology

authors： Ammons WS,Blair RW,Foreman RD

更新日期：1983-10-01 00:00:00

abstract：:Transection of a peripheral nerve results in withdrawal of synapses from motoneurons. Some of the withdrawn synapses are restored spontaneously, but those containing the vesicular glutamate transporter 1 (VGLUT1), and arising mainly from primary afferent neurons, are withdrawn permanently. If animals are exercised imm...

journal_title：Journal of neurophysiology

authors： Brandt J,Evans JT,Mildenhall T,Mulligan A,Konieczny A,Rose SJ,English AW

更新日期：2015-04-01 00:00:00

abstract：:Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep because loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wake- and sleep-regulatory nuclei to control behavioral states. Using survival analysis of wa...

journal_title：Journal of neurophysiology

authors： Diniz Behn CG,Kopell N,Brown EN,Mochizuki T,Scammell TE

更新日期：2008-06-01 00:00:00

abstract：:Despite the importance of the thumb to hand function, little is known about the origins of thumb impairment poststroke. Accordingly, the primary purpose of this study was to assess whether thumb flexors have heightened stretch reflexes (SRs) following stroke-induced hand impairment. The secondary purpose was to compar...

journal_title：Journal of neurophysiology

authors： Towles JD,Kamper DG,Rymer WZ

更新日期：2010-10-01 00:00:00

abstract：:The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...

journal_title：Journal of neurophysiology

authors： Cao J,Dorris DM,Meitzen J

更新日期：2018-10-01 00:00:00

abstract：:In adult songbirds, auditory neurons in the primary auditory forebrain region of field L and a secondary auditory forebrain region of caudal mesopallium (CM) are highly responsive to natural sounds, such as conspecific song. Because these nuclei are involved in sensory representations of songs, we investigated how the...

journal_title：Journal of neurophysiology

authors： Amin N,Doupe A,Theunissen FE

更新日期：2007-05-01 00:00:00

abstract：:1. A novel approach for analyzing transients in passive structures called "the method of moments" is introduced. It provides, as a special case, an analytic method for calculating the time delay and speed of propagation of electrical signals in any passive dendritic tree without the need for numerical simulations. 2. ...

journal_title：Journal of neurophysiology

authors： Agmon-Snir H,Segev I

更新日期：1993-11-01 00:00:00

abstract：:The recurrent mossy fiber pathway of the dentate gyrus expands dramatically in many persons with temporal lobe epilepsy. The new connections among granule cells provide a novel mechanism of synchronization that could enhance the participation of these cells in seizures. Despite the presence of robust recurrent mossy f...

journal_title：Journal of neurophysiology

authors： Hardison JL,Okazaki MM,Nadler JV

更新日期：2000-11-01 00:00:00

abstract：:1. Neurons in the ventral intraparietal area (VIP) are known to respond to translating random dot patterns. Such responses can be explained on the basis of the input of the middle temporal area (MT) to this area. Anatomic evidence has shown that VIP receives input from the dorsal part of the medial superior temporal a...

journal_title：Journal of neurophysiology

authors： Schaafsma SJ,Duysens J

更新日期：1996-12-01 00:00:00

abstract：:Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains. J. Neurophysiol. 80: 3345-3351, 1998. A model of two lateral geniculate nucleus (LGN) cells, which interact only through slow (tens of seconds) covariations in their resting membrane potentials, is...

journal_title：Journal of neurophysiology

authors： Brody CD

更新日期：1998-12-01 00:00:00

abstract：:Previous research has described kinetic characteristics of treadmill steps in very stable steppers, in cross-sectional designs. In this study we examined, longitudinally, muscle activation patterns during treadmill stepping, without practice, in 12 healthy infants at 1, 6, and 12 mo of age. We assessed lateral gastroc...

journal_title：Journal of neurophysiology

authors： Teulier C,Sansom JK,Muraszko K,Ulrich BD

更新日期：2012-08-01 00:00:00

abstract：:Action-potential propagation into the axon terminals of olfactory receptor cells was measured with the use of voltage-sensitive dye imaging in the isolated spiny lobster brain. Conditioning shocks to the olfactory nerve, known to cause long-lasting suppression of olfactory lobe neurons, allowed the selective imaging o...

journal_title：Journal of neurophysiology

authors： Wachowiak M,Cohen LB

更新日期：1998-08-01 00:00:00

abstract：:To trigger action potentials in neurons, most investigators use electrical or chemical stimulation. Here we describe an optical stimulation method based on semi-synthetic light-activated ion channels. These SPARK (synthetic photoisomerizable azobenzene-regulated K(+)) channels consist of a synthetic azobenzene-contain...

journal_title：Journal of neurophysiology

authors： Chambers JJ,Banghart MR,Trauner D,Kramer RH

更新日期：2006-11-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM)...

journal_title：Journal of neurophysiology

authors： Bikson M,Baraban SC,Durand DM

更新日期：2002-01-01 00:00:00