A population of gap junction-coupled neurons drives recurrent network activity in a developing visual circuit.

abstract：:1. Extracellular bath application of the selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor KN-62 to hippocampal slices in vitro blocked the induction of long-term depression (LTD) by low-frequency Schaffer collateral stimulation (1 Hz/15 min) of the same concentration as has been shown previously to pre...

journal_title：Journal of neurophysiology

authors： Stanton PK,Gage AT

更新日期：1996-09-01 00:00:00

abstract：:The electrical activity of 168 individual neurons located in the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis, and ventralis, has been recorded in precollicular decerebrate cats during sinusoidal tilt about the longitudinal axis of the whole...

journal_title：Journal of neurophysiology

authors： Manzoni D,Pompeiano O,Stampacchia G,Srivastava UC

更新日期：1983-11-01 00:00:00

abstract：:The extracellular pH of living tissue in the retina and elsewhere in the brain is lower than the pH of the surrounding milieu. We have shown that the pH gradient between the in vitro retina and the superfusion solution is regulated by a circadian (24-h) clock so that it is smaller in the subjective day than in the sub...

journal_title：Journal of neurophysiology

authors： Dmitriev AV,Mangel SC

更新日期：2004-06-01 00:00:00

abstract：:In free viewing, the eyes return to previously visited locations rather frequently, even though the attentional and memory-related processes controlling eye-movement show a strong antirefixation bias. To overcome this bias, a special refixation triggering mechanism may have to be recruited. We probed the neural eviden...

journal_title：Journal of neurophysiology

authors： Nikolaev AR,Meghanathan RN,van Leeuwen C

更新日期：2018-11-01 00:00:00

abstract：:Senosory neurons manifest pronounced changes in excitability during maturation, but the factors contributing to this ubiquitous developmental phenomenon are not well understood. To assess the contribution of intrinsic membrane properties to such changes in excitability, in the present study whole cell patch-clamp reco...

journal_title：Journal of neurophysiology

authors： Wang GY,Ratto G,Bisti S,Chalupa LM

更新日期：1997-12-01 00:00:00

abstract：:Understanding neural responses with natural stimuli has increasingly become an essential part of characterizing neural coding. Neural responses are commonly characterized by a linear-nonlinear (LN) model, in which the output of a linear filter applied to the stimulus is transformed by a static nonlinearity to determin...

journal_title：Journal of neurophysiology

authors： Sharpee TO,Miller KD,Stryker MP

更新日期：2008-05-01 00:00:00

abstract：:Rhythmic movements of the gastric mill and pyloric regions of the crustacean foregut are controlled by two stomatogastric neuronal networks that have been intensively studied in vitro. By using electromyographic recordings from the European lobster, Homarus gammarus, we have monitored simultaneously the motor activity...

journal_title：Journal of neurophysiology

authors： Clemens S,Combes D,Meyrand P,Simmers J

更新日期：1998-03-01 00:00:00

abstract：:Because vagal and sympathetic inputs activate upper cervical spinal neurons, we hypothesized that stimulation of the esophagus would activate C(1)-C(2) neurons. This study examined responses of C(1)-C(2) spinal neurons to cervical and thoracic esophageal distension (CED, TED) and afferent pathways for CED and TED inpu...

journal_title：Journal of neurophysiology

authors： Qin C,Chandler MJ,Jou CJ,Foreman RD

更新日期：2004-05-01 00:00:00

abstract：:Multimodal sensory integration facilitates the generation of a unified and coherent perception of the environment. It is now well established that unimodal sensory perceptions, such as vision, are improved in multisensory contexts. Whereas multimodal integration is primarily performed by dedicated multisensory brain r...

journal_title：Journal of neurophysiology

authors： McClure JP Jr,Polack PO

更新日期：2019-06-01 00:00:00

abstract：:The contribution of ascending afferents to the control of speech movement was evaluated by applying unanticipated loads to the lower lip during the generation of combined upper lip-lower lip speech gestures. To eliminate potential contamination due to anticipation or adaptation, loads were applied randomly on only 10-...

journal_title：Journal of neurophysiology

authors： Abbs JH,Gracco VL

更新日期：1984-04-01 00:00:00

abstract：:Human subjects chose between two color-coded reach targets using multicolored checkerboard-like decision cues (DCs) that presented variable amounts of conflicting sensory evidence supporting both target choices. Different DCs contained different numbers of small squares of the two target colors. The most ambiguous DCs...

journal_title：Journal of neurophysiology

authors： Coallier É,Kalaska JF

更新日期：2014-12-01 00:00:00

abstract：:1. The dentate gyrus fails to develop epileptiform activity in many experimental models of epilepsy, including the in vitro low-Ca2+ model. Although manipulating the K+ concentration or osmolality of normal low-Ca2+ perfusion mediums can enhance the propensity of the dentate gyrus to develop seizure activity, the spec...

journal_title：Journal of neurophysiology

authors： Richardson TL,O'Reilly CN

更新日期：1995-07-01 00:00:00

abstract：:1. In the intact pond snail Planorbis corneus, a rapid tilt in any plane evoked a defense reaction consisting of a fast movement of the shell towards the head, shortening of the foot, inhibition of locomotion and of rhythmical feeding movements. This reaction was similar to the first phase of the general defense react...

journal_title：Journal of neurophysiology

authors： Arshavsky YI,Deliagina TG,Okshtein IL,Orlovsky GN,Panchin YV,Popova LB

更新日期：1994-03-01 00:00:00

abstract：:The horizontal cell is a second-order retinal neuron that is depolarized in the dark and responds to light with graded potential changes. In such a nonspiking neuron, not only the voltage-gated ionic conductances but also Ca(2+) regulation mechanisms, e.g., the Na(+)/Ca(2+) exchange and the Ca(2+) pump, are considered...

journal_title：Journal of neurophysiology

authors： Hayashida Y,Yagi T

更新日期：2002-01-01 00:00:00

abstract：:Smoothness is a hallmark of healthy movement. Past research indicates that smoothness may be a side product of a control strategy that minimizes error. However, this is not the only reason for smooth movements. Our musculoskeletal system itself contributes to movement smoothness: the mechanical impedance (inertia, dam...

journal_title：Journal of neurophysiology

authors： Salmond LH,Davidson AD,Charles SK

更新日期：2017-03-01 00:00:00

abstract：:This study examined the effect of chronic exposure to ethanol on gamma-aminobutyric acid type-A (GABA(A)) receptor-mediated responses of layer II pyramidal neurons of the piriform cortex. Slices containing the piriform cortex were derived from pair-fed adult rats maintained on ethanol-supplemented or control liquid di...

journal_title：Journal of neurophysiology

authors： Signore AP,Yeh HH

更新日期：2000-07-01 00:00:00

abstract：:1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, par...

journal_title：Journal of neurophysiology

authors： Mackel R,Miyashita E

更新日期：1993-05-01 00:00:00

abstract：:1. We have examined the effects of iontophoresing specific antagonists to excitatory amino acid receptors on the visual responses of cells in lamina A or A1 of the cat's lateral geniculate nucleus (LGN). 2. Cells were classified as On- or Off-center, X or Y, and lagged or nonlagged. The effects of antagonists were stu...

journal_title：Journal of neurophysiology

authors： Kwon YH,Esguerra M,Sur M

更新日期：1991-08-01 00:00:00

abstract：:Two identified locust neurons, the lobula giant movement detector (LGMD) and its postsynaptic partner, the descending contralateral movement detector (DCMD), constitute one motion-sensitive pathway in the visual system that responds preferentially to objects that approach on a direct collision course and are implicate...

journal_title：Journal of neurophysiology

authors： McMillan GA,Gray JR

更新日期：2012-08-01 00:00:00

abstract：:People naturally direct their gaze to visible hand movement goals. Doing so improves reach accuracy through use of signals related to gaze position and visual feedback of the hand. Here, we studied where people naturally look when acting on remembered target locations. Four targets were presented on a screen, in perip...

journal_title：Journal of neurophysiology

authors： Flanagan JR,Terao Y,Johansson RS

更新日期：2008-09-01 00:00:00

abstract：:1. Microelectrodes filled with horseradish peroxidase (HRP) were inserted in the superior colliculus (SC) of alert squirrel monkeys. Spontaneous eye movements were monitored in the dark during recording and intraaxonal injection of fibers carrying presaccadic signals. 2. Analysis of the relationship between neuronal a...

journal_title：Journal of neurophysiology

authors： Moschovakis AK,Karabelas AB,Highstein SM

更新日期：1988-07-01 00:00:00

abstract：:Unitary pallido-nigral synaptic currents were measured using optogenetic stimulation, which activated up to three unitary synaptic inputs to each substantia nigra pars reticulata (SNr) cell. Episodic barrages of synaptic conductances were generated based on in vivo firing patterns of globus pallidus pars externa (GPe)...

journal_title：Journal of neurophysiology

authors： Simmons DV,Higgs MH,Lebby S,Wilson CJ

更新日期：2020-02-01 00:00:00

abstract：:Systemic exposure to N-methyl-d-aspartate (NMDA) receptor antagonists can lead to psychosis and prefrontal cortex (PFC)-dependent behavioral impairments. Agonists of metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate the adverse behavioral effects of NMDA antagonists in humans and laboratory animals, and are be...

journal_title：Journal of neurophysiology

authors： Homayoun H,Jackson ME,Moghaddam B

更新日期：2005-04-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:The aim of this study was to investigate how maximal intermittent contractions for a hand muscle influence cortical and reflex activity, as well as the ability to voluntarily activate, the homologous muscle in the opposite limb. Twelve healthy subjects (age: 24 ± 3 years, all right hand dominant) performed maximal con...

journal_title：Journal of neurophysiology

authors： Kavanagh JJ,Feldman MR,Simmonds MJ

更新日期：2016-11-01 00:00:00

abstract：:Clinical and experimental research has demonstrated that the emotional experience of fear and anxiety impairs postural stability in humans. The current study investigated whether changes in fear and anxiety can also modulate spinal stretch reflexes and the gain of afferent inputs to the primary somatosensory cortex. T...

journal_title：Journal of neurophysiology

authors： Davis JR,Horslen BC,Nishikawa K,Fukushima K,Chua R,Inglis JT,Carpenter MG

更新日期：2011-12-01 00:00:00

abstract：:1. Over two thirds of caudal medullary raphespinal neurons respond to electrical stimulation of the vestibular nerve, and it has been suggested that these neurons may participate in the generation of vestibulospinal and vestibulosympathetic reflexes. The objective of the present study was to determine which vestibular...

journal_title：Journal of neurophysiology

authors： Yates BJ,Goto T,Kerman I,Bolton PS

更新日期：1993-09-01 00:00:00

abstract：:Several studies have demonstrated that motor adaptations to a novel task environment can be transferred between limbs. Such interlimb transfer of motor commands is consistent with the notion of centrally driven strategies that can be generalized across different frames of reference. So far, studies of interlimb transf...

journal_title：Journal of neurophysiology

authors： Houldin A,Chua R,Carpenter MG,Lam T

更新日期：2012-08-01 00:00:00

abstract：:Experiments were performed on human elbow flexor and extensor muscles and jaw-opening and -closing muscles to observe the effect on rhythmic movements of sudden loading. The load was provided by an electromagnetic device, which simulated the appearance of a smoothly increasing spring-like load. The responses to this l...

journal_title：Journal of neurophysiology

authors： Abbink JH,van der Bilt A,Bosman F,van der Glas HW,Erkelens CJ,Klaassen MF

更新日期：1999-09-01 00:00:00

abstract：:The responses of cortical neurons to repeated presentation of a stimulus are highly variable, yet correlated. These "noise correlations" reflect a low-dimensional structure of population dynamics. Here, we examine noise correlations in 22,705 pairs of neurons in primary visual cortex (V1) of anesthetized cats, during ...

journal_title：Journal of neurophysiology

authors： Schulz DP,Sahani M,Carandini M

更新日期：2015-08-01 00:00:00