Gaze behavior when reaching to remembered targets.

Abstract:

:People naturally direct their gaze to visible hand movement goals. Doing so improves reach accuracy through use of signals related to gaze position and visual feedback of the hand. Here, we studied where people naturally look when acting on remembered target locations. Four targets were presented on a screen, in peripheral vision, while participants fixed a central cross (encoding phase). Four seconds later, participants used a pen to mark the remembered locations while free to look wherever they wished (recall phase). Visual references, including the screen and the cross, were present throughout. During recall, participants neither looked at the marked locations nor prevented eye movements. Instead, gaze behavior was erratic and was comprised of gaze shifts loosely coupled in time and space with hand movements. To examine whether eye and hand movements during encoding affected gaze behavior during recall, in additional encoding conditions, participants marked the visible targets with either free gaze or with central cross fixation or just looked at the targets. All encoding conditions yielded similar erratic gaze behavior during recall. Furthermore, encoding mode did not influence recall performance, suggesting that participants, during recall, did not exploit sensorimotor memories related to hand and gaze movements during encoding. Finally, we recorded a similar lose coupling between hand and eye movements during an object manipulation task performed in darkness after participants had viewed the task environment. We conclude that acting on remembered versus visible targets can engage fundamentally different control strategies, with gaze largely decoupled from movement goals during memory-guided actions.

journal_name

J Neurophysiol

authors

Flanagan JR,Terao Y,Johansson RS

doi

10.1152/jn.90518.2008

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

1533-43

issue

3

eissn

0022-3077

issn

1522-1598

pii

90518.2008

journal_volume

100

pub_type

杂志文章
  • Kv1 potassium channel complexes in vivo require Kvbeta2 subunits in dorsal spinal neurons.

    abstract::Whereas Kvbeta2 subunits modulate potassium current properties carried by Kv1 channel complexes in heterologous systems, little is known about the contributions of Kvbeta2 subunits to native potassium channel function. Using antisense approaches and in situ recordings from Xenopus embryo spinal cord neurons, we tested...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90667.2008

    authors: Pineda RH,Knoeckel CS,Taylor AD,Estrada-Bernal A,Ribera AB

    更新日期:2008-10-01 00:00:00

  • Local anesthetics block transient outward potassium currents in rat neocortical neurons.

    abstract::1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.6.1966

    authors: Andreasen M,Hablitz JJ

    更新日期:1993-06-01 00:00:00

  • Thermoregulatory vasomotor tone of the rat tail and paws in thermoneutral conditions and its impact on a behavioral model of acute pain.

    abstract::The tail and paws in rodents are heat exchangers involved in the maintenance of core body temperature (T(core)). They are also the most widely used target organs to study acute or chronic "models" of pain. We describe the fluctuations of vasomotor tone in the tail and paws in conditions of thermal neutrality and the c...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00721.2013

    authors: El Bitar N,Pollin B,Karroum E,Pincedé I,Mouraux A,Le Bars D

    更新日期:2014-11-01 00:00:00

  • Plateau pattern of afferent discharge rate from frog muscle spindles.

    abstract::1. A characteristic plateau pattern was observed in the rate of afferent discharges during ramp-and-hold stretch of spindles isolated from semitendinosus muscles of frogs. The plateau pattern was more frequent in summer frogs (84%) than winter frogs (11%). 2. The plateau pattern consisted of a discharge rate around 12...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.275

    authors: Sokabe M,Nunogaki K,Naruse K,Soga H,Fujitsuka N,Yoshimura A,Ito F

    更新日期:1993-07-01 00:00:00

  • Is the olfactory bulb computationally similar to the retina?

    abstract::The computational role of the olfactory bulb remains a mystery after 60 yr of physiological research. Recently, Fantana and colleagues proposed a new model of bulb function based on sparse inhibitory connections between glomeruli, the functional units of the bulb, rather than the existing lateral inhibition model. I p...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.91146.2008

    authors: Ghatpande AS

    更新日期:2009-01-01 00:00:00

  • Calcium spike-mediated digital signaling increases glutamate output at the visual threshold of retinal bipolar cells.

    abstract::Most retinal bipolar cells (BCs) transmit visual input from photoreceptors to ganglion cells using graded potentials, but some also generate calcium or sodium spikes. Sodium spikes are thought to increase temporal precision of light-evoked BC signaling; however, the role of calcium spikes in BCs is not fully understoo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00378.2014

    authors: Lipin MY,Vigh J

    更新日期:2015-01-15 00:00:00

  • Vestibular nuclei and cerebellum put visual gravitational motion in context.

    abstract::Animal survival in the forest, and human success on the sports field, often depend on the ability to seize a target on the fly. All bodies fall at the same rate in the gravitational field, but the corresponding retinal motion varies with apparent viewing distance. How then does the brain predict time-to-collision unde...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00889.2007

    authors: Miller WL,Maffei V,Bosco G,Iosa M,Zago M,Macaluso E,Lacquaniti F

    更新日期:2008-04-01 00:00:00

  • Coexpression of multiple metabotropic glutamate receptors in axon terminals of single suprachiasmatic nucleus neurons.

    abstract::Glutamate is the primary excitatory transmitter in axons innervating the hypothalamic suprachiasmatic nucleus (SCN) and is responsible for light-induced phase shifts of circadian rhythms generated by the SCN. By using self-innervating single neuron cultures and patch-clamp electrophysiology, we studied metabotropic gl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.80.4.1932

    authors: Chen G,van den Pol AN

    更新日期:1998-10-01 00:00:00

  • Branching points of primary afferent fibers are vital for the modulation of fiber excitability by epidural DC polarization and by GABA in the rat spinal cord.

    abstract::The aim of the study was to examine whether the sustained increases in the excitability of afferent fibers traversing the dorsal columns evoked by their polarization depend on the branching points of these fibers. To this end, the effects of epidural polarization were compared in four spinal regions in deeply anesthet...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00161.2020

    authors: Li Y,Hari K,Lucas-Osma AM,Fenrich KK,Bennett DJ,Hammar I,Jankowska E

    更新日期:2020-07-01 00:00:00

  • Progression in neuronal processing for saccadic eye movements from parietal cortex area lip to superior colliculus.

    abstract::Neurons in both the lateral intraparietal area (LIP) of the monkey parietal cortex and the intermediate layers of the superior colliculus (SC) are activated well in advance of the initiation of saccadic eye movements. To determine whether there is a progression in the covert processing for saccades from area LIP to SC...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.85.6.2545

    authors: Paré M,Wurtz RH

    更新日期:2001-06-01 00:00:00

  • Encoding of movement dynamics by Purkinje cell simple spike activity during fast arm movements under resistive and assistive force fields.

    abstract::It is controversial whether simple-spike activity of cerebellar Purkinje cells during arm movements encodes movement kinematics like velocity or dynamics like muscle activities. To examine this issue, we trained monkeys to flex or extend the elbow by 45 degrees in 400 ms under resistive and assistive force fields but ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00206.2006

    authors: Yamamoto K,Kawato M,Kotosaka S,Kitazawa S

    更新日期:2007-02-01 00:00:00

  • Cone inputs in macaque primary visual cortex.

    abstract::To understand the role of primary visual cortex (V1) in color vision, we measured directly the input from the 3 cone types in macaque V1 neurons. Cells were classified as luminance-preferring, color-luminance, or color-preferring from the ratio of the peak amplitudes of spatial frequency responses to red/green equilum...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01043.2003

    authors: Johnson EN,Hawken MJ,Shapley R

    更新日期:2004-06-01 00:00:00

  • Choline acts as agonist and blocker for Aplysia cholinergic synapses.

    abstract::Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1984.51.1.1

    authors: Gardner D,Ruff RL,White RL

    更新日期:1984-01-01 00:00:00

  • Local-distributed integration by a novel neuron ensures rapid initiation of animal locomotion.

    abstract::Animals are adapted to respond quickly to threats in their environment. In many invertebrate and some vertebrate species, the evolutionary pressures have resulted in rapidly conducting giant axons, which allow short response times. Although neural circuits mediating escape behavior are identified in several species, l...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00507.2010

    authors: Mullins OJ,Hackett JT,Friesen WO

    更新日期:2011-01-01 00:00:00

  • Large-scale identification of proteins involved in the development of a sexually dimorphic behavior.

    abstract::Sexually dimorphic behaviors develop under the influence of sex steroids, which induce reversible changes in the underlying neural network of the brain. However, little is known about the proteins that mediate these activational effects of sex steroids. Here, we used a proteomics approach for large-scale identificatio...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00750.2013

    authors: Zupanc GK,Ilies I,Sîrbulescu RF,Zupanc MM

    更新日期:2014-04-01 00:00:00

  • Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses.

    abstract::Activation of metabotropic glutamate receptors (mGluRs), which are coupled to G proteins, has important roles in certain forms of synaptic plasticity including corticostriatal long-term depression (LTD). In the present study, extracellular field potential and whole cell voltage-clamp recording techniques were used to ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.86.5.2405

    authors: Sung KW,Choi S,Lovinger DM

    更新日期:2001-11-01 00:00:00

  • Enhanced Ih depresses rat entopeduncular nucleus neuronal activity from high-frequency stimulation or raised Ke+.

    abstract::High-frequency stimulation (HFS) is used to treat a variety of neurological diseases, yet its underlying therapeutic action is not fully elucidated. Previously, we reported that HFS-induced elevation in [K(+)](e) or bath perfusion of raised K(e)(+) depressed rat entopeduncular nucleus (EP) neuronal activity via an enh...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01065.2007

    authors: Shin DS,Carlen PL

    更新日期:2008-05-01 00:00:00

  • Synaptic depression in conjunction with A-current channels promote phase constancy in a rhythmic network.

    abstract::In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00640.2004

    authors: Greenberg I,Manor Y

    更新日期:2005-02-01 00:00:00

  • Motor imagery in multiple sclerosis: exploring applications in therapeutic treatment.

    abstract::Motor imagery (MI) is a promising rehabilitation technique that has received significant interest for use in persons with multiple sclerosis (MS). Through alterations in neural networks, MI has the potential to improve measures of walking speed, walking distance, and fatigue in people with MS. Further research is requ...

    journal_title:Journal of neurophysiology

    pub_type: 评论,杂志文章

    doi:10.1152/jn.00291.2018

    authors: Hanson M,Concialdi M

    更新日期:2019-02-01 00:00:00

  • Differential processing of the direction and focus of expansion of optic flow stimuli in areas MST and V3A of the human visual cortex.

    abstract::Human neuropsychological and neuroimaging studies have raised the possibility that different attributes of optic flow stimuli, namely radial direction and the position of the focus of expansion (FOE), are processed within separate cortical areas. In the human brain, visual areas V5/MT+ and V3A have been proposed as in...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00031.2017

    authors: Strong SL,Silson EH,Gouws AD,Morland AB,McKeefry DJ

    更新日期:2017-06-01 00:00:00

  • Single-unit stability using chronically implanted multielectrode arrays.

    abstract::The use of chronic intracortical multielectrode arrays has become increasingly prevalent in neurophysiological experiments. However, it is not obvious whether neuronal signals obtained over multiple recording sessions come from the same or different neurons. Here, we develop a criterion to assess single-unit stability...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90920.2008

    authors: Dickey AS,Suminski A,Amit Y,Hatsopoulos NG

    更新日期:2009-08-01 00:00:00

  • Kinematic strategies in newly walking toddlers stepping over different support surfaces.

    abstract::In adults, locomotor movements are accommodated to various support surface conditions by means of specific anticipatory locomotor adjustments and changes in the intersegmental coordination. Here we studied the kinematic strategies of toddlers at the onset of independent walking when negotiating various support surface...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00945.2009

    authors: Dominici N,Ivanenko YP,Cappellini G,Zampagni ML,Lacquaniti F

    更新日期:2010-03-01 00:00:00

  • Neural processing of stereopsis as a function of viewing distance in primate visual cortical area V1.

    abstract::1. The influence of viewing distance on disparity selectivity was investigated in area V1 of behaving monkeys. While the animals performed a fixation task, cortical cells were recorded extracellularly in the foveal representation of the visual field. Disparity selectivity was assessed by using static random dot stereo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.76.5.2872

    authors: Trotter Y,Celebrini S,Stricanne B,Thorpe S,Imbert M

    更新日期:1996-11-01 00:00:00

  • Plasticity in the mediodorsal thalamo-prefrontal cortical transmission in behaving mice.

    abstract::We studied changes in thalamo-prefrontal cortical transmission in behaving mice following both low-frequency stimulation of the mediodorsal thalamus (MD) and during extinction of a conditioned fear response. Electrical stimulation of the MD induces a field potential in the medial prefrontal cortex (mPFC) characterized...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.5.2827

    authors: Herry C,Vouimba RM,Garcia R

    更新日期:1999-11-01 00:00:00

  • Effects of anoxia on rat midbrain dopamine neurons.

    abstract::1. Dopamine-containing neurons of the rat midbrain were recorded intracellularly in vitro. Anoxia (2-5 min) caused reversible membrane hyperpolarization (4-25 mV), which blocked spontaneous firing of action potentials. Under voltage clamp, anoxia produced an outward current (100-1,000 pA) associated with an increase i...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.71.3.1165

    authors: Mercuri NB,Bonci A,Johnson SW,Stratta F,Calabresi P,Bernardi G

    更新日期:1994-03-01 00:00:00

  • Impulse rates and sensitivity to stretch of soleus muscle spindle afferent fibers during locomotion in premammillary cats.

    abstract::Impulse from soleus muscle afferents were recorded in premammillary cats that were walking on a treadmill. In normal walking the effects of gamma-motoneurons on impulse rates of muscle spindle afferents are confounded by the effects of the large length changes that occur. To isolate the effects of gamma-motoneurons th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1985.53.2.341

    authors: Taylor J,Stein RB,Murphy PR

    更新日期:1985-02-01 00:00:00

  • Large-scale organization of preferred directions in the motor cortex. II. Analysis of local distributions.

    abstract::The spatial arrangement of preferred directions (PDs) in the primary motor cortex has revealed evidence for columnar organization and short-range order. We investigated the large-scale properties of this arrangement. We recorded neural activity at sites on a grid covering a large region of the arm area of the motor co...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00488.2006

    authors: Naselaris T,Merchant H,Amirikian B,Georgopoulos AP

    更新日期:2006-12-01 00:00:00

  • Selectivity of inferior temporal neurons for realistic pictures predicted by algorithms for image database navigation.

    abstract::Primates have a remarkable ability to perceive, recognize, and discriminate among the plethora of people, places, and things that they see, and neural selectivity in the primate inferotemporal (IT) cortex is thought to underlie this ability. Here we investigated the relationship between neural response and perception ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00130.2005

    authors: Allred S,Liu Y,Jagadeesh B

    更新日期:2005-12-01 00:00:00

  • Segmental specialization of calcium-activated potassium conductances in an identified leech neuron.

    abstract::1. Retzius (R) neurons of the fifth and sixth segmental ganglia of the leech, called R(5,6) neurons are specialized to innervate the adjacent reproductive organs and are morphologically and functionally distinct from R neurons of standard ganglia [R(x) cells]. In this study the electrical properties of the R(x) and R(...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.73.3.957

    authors: Merz DC

    更新日期:1995-03-01 00:00:00

  • Proximal arm kinematics affect grip force-load force coordination.

    abstract::During object manipulation, grip force is coordinated with load force, which is primarily determined by object kinematics. Proximal arm kinematics may affect grip force control, as proximal segment motion could affect control of distal hand muscles via biomechanical and/or neural pathways. The aim of this study was to...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00227.2015

    authors: Vermillion BC,Lum PS,Lee SW

    更新日期:2015-10-01 00:00:00