Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses.

abstract：:Respiratory depression is a therapy-limiting side effect of opioid analgesics, yet our understanding of the brain circuits mediating this potentially lethal outcome remains incomplete. Here we studied the contribution of the rostral ventromedial medulla (RVM), a region long implicated in pain modulation and homeostati...

journal_title：Journal of neurophysiology

authors： Phillips RS,Cleary DR,Nalwalk JW,Arttamangkul S,Hough LB,Heinricher MM

更新日期：2012-11-01 00:00:00

abstract：:Reaching to grasp is of fundamental importance to primate motor behavior and requires coordinating hand preshaping with limb transport and grasping. We aimed to clarify the role of cerebellar output via the magnocellular red nucleus (RNm) to the control of reaching to grasp. Rubrospinal fibers originating from RNm con...

journal_title：Journal of neurophysiology

authors： van Kan PL,McCurdy ML

更新日期：2001-04-01 00:00:00

abstract：:1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

journal_title：Journal of neurophysiology

authors： Pflug R,Nelson R,Ahnelt PK

更新日期：1990-08-01 00:00:00

abstract：:Echolocating bats use echoes of their sonar emissions to determine the position and distance of objects or prey. Target distance is represented as a map of echo delay in the auditory cortex (AC) of bats. During a bat's flight through a natural complex environment, echo streams are reflected from multiple objects along...

journal_title：Journal of neurophysiology

authors： Greiter W,Firzlaff U

更新日期：2017-06-01 00:00:00

abstract：:The effect of L-glutamate on muscle fibers of the anterior aorta of the marine gastropod Aplysia are characterized. Iontophoretically applied L-glutamate depolarized anterior aorta muscle fibers in 14% of the applications; no response was detected in the other applications. Responses to iontophoretically applied L-glu...

journal_title：Journal of neurophysiology

authors： Sawada M,Gibson D,McAdoo DJ

更新日期：1984-02-01 00:00:00

abstract：:Hypercapnia-induced arousal from sleep is an important protective mechanism pertinent to a number of diseases. Most notably among these are the sudden infant death syndrome, obstructive sleep apnea and sudden unexpected death in epilepsy. Serotonin (5-HT) plays a significant role in hypercapnia-induced arousal. The me...

journal_title：Journal of neurophysiology

authors： Buchanan GF,Smith HR,MacAskill A,Richerson GB

更新日期：2015-07-01 00:00:00

abstract：:1. Monkeys with large unilateral surgical ablations of striate cortex, sustained either in adulthood or at 5-6 wk of age, were trained on an oculomotor detection and localization task and tested with visual stimuli in the hemifields ipsilateral and contralateral to the lesion 2-5 yr after surgery. 2. Monkeys with lesi...

journal_title：Journal of neurophysiology

authors： Moore T,Rodman HR,Repp AB,Gross CG,Mezrich RS

更新日期：1996-12-01 00:00:00

abstract：:Poststroke pain syndrome (PSPS) is an often intractable disorder characterized by hemiparesis associated with unrelenting chronic pain. Although traditional analgesics have largely failed, integrative approaches targeting affective-cognitive spheres have started to show promise. Recently, we demonstrated that deep bra...

journal_title：Journal of neurophysiology

authors： Gopalakrishnan R,Burgess RC,Malone DA,Lempka SF,Gale JT,Floden DP,Baker KB,Machado AG

更新日期：2018-06-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:1. Transmission at electrical synapses is modulated by a variety of physiological signals, and this modulation is a potentially general mechanism for regulating signal integration in neural circuits and networks. In the outer plexiform layer of the retina, modulation of horizontal-cell electrical coupling by dopamine ...

journal_title：Journal of neurophysiology

authors： McMahon DG,Brown DR

更新日期：1994-11-01 00:00:00

abstract：:1. Taste buds in catfish are found not only within the oropharyngeal cavity, as in mammals, but are also located along the external body surface of the animal from the barbels and lips to the caudal fin. Because these taste buds are innervated by the facial (cranial VII) nerve, the extraoral taste system of catfish is...

journal_title：Journal of neurophysiology

authors： Michel W,Caprio J

更新日期：1991-07-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:1. We studied the frequency responses of neurons in the nucleus ovoidalis (OV), the principal thalamic auditory relay nucleus of the chicken, in the subthreshold range of membrane potentials. The frequency response is the impedance amplitude profile evident in the voltage response to a broadband stimulus. The stimulus...

journal_title：Journal of neurophysiology

authors： Ströhmann B,Schwarz DW,Puil E

更新日期：1994-04-01 00:00:00

abstract：:1. Presynaptic inhibition of synaptic transmission in the hippocampus was investigated by comparing the effects of several agonists on miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs). 2. The Ca2+ ionophore ionomycin increased the frequency of mEPSCs and mIPSCs but did not affect their amp...

journal_title：Journal of neurophysiology

authors： Capogna M,Gähwiler BH,Thompson SM

更新日期：1996-05-01 00:00:00

abstract：:GABAergic interneurons in the hippocampus express high levels of alpha7 nicotinic acetylcholine receptors, but because of the diverse roles played by hippocampal interneurons, the impact of activation of these receptors on hippocampal output neurons (i.e., CA1 pyramidal cells) is unclear. Activation of hippocampal int...

journal_title：Journal of neurophysiology

authors： Buhler AV,Dunwiddie TV

更新日期：2002-01-01 00:00:00

abstract：:The plant-derived insecticides have introduced a new concept in insecticide research. In response to insect attacks, some plants can release volatile sulfur compounds such as dimethyl disulfide (DMDS) in the atmosphere, which are lethal for the generalist insects. We demonstrate that DMDS induced an uncommon complex n...

journal_title：Journal of neurophysiology

authors： Dugravot S,Grolleau F,Macherel D,Rochetaing A,Hue B,Stankiewicz M,Huignard J,Lapied B

更新日期：2003-07-01 00:00:00

abstract：:Visual search is a ubiquitous visual behavior, and efficient search is essential for survival. Different cognitive models have explained the speed and accuracy of search based either on the dynamics of attention or on similarity of item representations. Here, we examined the extent to which performance on a visual sea...

journal_title：Journal of neurophysiology

authors： Cohen MA,Alvarez GA,Nakayama K,Konkle T

更新日期：2017-01-01 00:00:00

abstract：:1. Evoked potentials restricted to the magnocellular portion of the mediodorsal nucleus (MDmc) of the thalamus were recorded after stimulation of the olfactory bulb (OB) and the posterior orbital cortex of the frontal lobe (OFC). Potentials evoked by stimulation of OB were probably trans-synaptically elicited, while p...

journal_title：Journal of neurophysiology

authors： Yarita H,Iino M,Tanabe T,Kogure S,Takagi SF

更新日期：1980-01-01 00:00:00

abstract：:1. Horizontal cells were enzymatically and mechanically dissociated from the white perch (Roccus americana) retina and voltage clamped using patch electrodes. Steady-state current-voltage (I-V) relationships of solitary horizontal cells were determined by changing the membrane potential in a rampwise fashion. 2. The I...

journal_title：Journal of neurophysiology

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1988-10-01 00:00:00

abstract：:1. The vestibuloocular reflex (VOR) undergoes long-term adaptive changes in the presence of persistent retinal image motion during head turns. Previous experiments using natural stimuli have provided evidence that the VOR is subserved by parallel pathways, including some that are modified during learning and some that...

journal_title：Journal of neurophysiology

authors： Broussard DM,Brontë-Stewart HM,Lisberger SG

更新日期：1992-06-01 00:00:00

abstract：:1. Single- and multiunit recordings were obtained from neurons in the auditory cortex of the echolocating bat Myotis lucifugus, while trains of stimuli designed to simulate the bat's frequency-modulated (FM) orientation pulse and its returning echo were delivered. It was found that many neurons in the cortex responded...

journal_title：Journal of neurophysiology

authors： Sullivan WE 3rd

更新日期：1982-10-01 00:00:00

abstract：:Mg2+-extrusion from Mg2+-loaded neurons of the leech, Hirudo medicinalis, is mediated mainly by Na+/Mg2+ antiport. However, in a number of leech neurons, Mg2+ is extruded in the nominal absence of extracellular Na+, indicating the existence of an additional, Na+-independent Mg2+ transport mechanism. This mechanism was...

journal_title：Journal of neurophysiology

authors： Günzel D,Hintz K,Durry S,Schlue WR

更新日期：2005-07-01 00:00:00

abstract：:1. Surgically resected tissue from the tip of the human temporal lobe of seven patients undergoing temporal lobectomy was employed to study functional properties of GABAergic inhibition mediated through activation of GABAA receptors, using patch-clamp recording techniques in acutely isolated neurons and in slices of h...

journal_title：Journal of neurophysiology

authors： Gibbs JW 3rd,Zhang YF,Kao CQ,Holloway KL,Oh KS,Coulter DA

更新日期：1996-04-01 00:00:00

abstract：:Generalizing newly learned movement patterns beyond the training context is challenging for most motor learning situations. Here we tested whether learning of a new physical property of the arm during self-initiated reaching generalizes to new arm configurations. Human participants performed a single-joint elbow reach...

journal_title：Journal of neurophysiology

authors： Maeda RS,Zdybal JM,Gribble PL,Pruszynski JA

更新日期：2020-03-01 00:00:00

abstract：:The medial division of the ventral nucleus of the lateral lemniscus (VNLLm) contains a specialized population of neurons that is sensitive to interaural temporal disparities (ITDs), a potent cue for sound localization along the azimuth. Unlike many ITD-sensitive neurons elsewhere in the auditory system, neurons in the...

journal_title：Journal of neurophysiology

authors： Batra R,Fitzpatrick DC

更新日期：2002-08-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:Behavioral studies have shown that object recognition becomes severely impaired at fast presentation rates, indicating a limitation in temporal processing capacity. Here, we studied whether this behavioral limit in object recognition reflects limitations in the temporal processing capacity of early visual areas tuned ...

journal_title：Journal of neurophysiology

authors： McKeeff TJ,Remus DA,Tong F

更新日期：2007-07-01 00:00:00

abstract：:Tinnitus is a phantom auditory perception without an external sound source and is one of the most common public health concerns that impair the quality of life of many individuals. However, its neural mechanisms remain unclear. We herein examined population-level frequency tuning in the auditory cortex of unilateral t...

journal_title：Journal of neurophysiology

authors： Sekiya K,Takahashi M,Murakami S,Kakigi R,Okamoto H

更新日期：2017-03-01 00:00:00

abstract：:Monoamines are strong modulators and/or activators of spinal locomotor networks. Thus monoaminergic fibers likely contact neurons involved in generating locomotion. The aim of the present study was to investigate the serotonergic innervation of locomotor-activated neurons within the thoraco-lumbar spinal cord followin...

journal_title：Journal of neurophysiology

authors： Noga BR,Johnson DM,Riesgo MI,Pinzon A

更新日期：2009-09-01 00:00:00

abstract：:Compression apparel is popular in both medical and sport performance settings. Perceived benefits are suggested to include changes in sensory feedback transmission caused by activation of mechanoreceptors. However, little is known about effects of compression apparel on sensorimotor control. Our purpose was to mechani...

journal_title：Journal of neurophysiology

authors： Barss TS,Pearcey GEP,Munro B,Bishop JL,Zehr EP

更新日期：2018-07-01 00:00:00