Coincidence detection in pyramidal neurons is tuned by their dendritic branching pattern.

abstract：:Long-term depression (LTD) was induced in neocortical layer 5 pyramidal connections by pairing presynaptic firing with subthreshold postsynaptic depolarization (dLTD) or via a spike-timing protocol (tLTD). Like tLTD, dLTD reduced short-term depression and increased the coefficient of variation consistent with a presyn...

journal_title：Journal of neurophysiology

authors： Sjöström PJ,Turrigiano GG,Nelson SB

更新日期：2004-12-01 00:00:00

abstract：:The Wilson-Cowan population model of neural activity has greatly influenced our understanding of the mechanisms for the generation of brain rhythms and the emergence of structured brain activity. As well as the many insights that have been obtained from its mathematical analysis, it is now widely used in the computati...

journal_title：Journal of neurophysiology

authors： Byrne Á,O'Dea RD,Forrester M,Ross J,Coombes S

更新日期：2020-02-01 00:00:00

abstract：:Amino acid and bile salt odorants are detected by zebrafish with relatively independent odorant receptors, but the transduction cascade(s) subsequently activated by these odorants remains unknown. Electro-olfactogram recording methods were used to determine the effects of two drugs, reported to affect phospholipase C ...

journal_title：Journal of neurophysiology

authors： Ma L,Michel WC

更新日期：1998-03-01 00:00:00

abstract：:Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

journal_title：Journal of neurophysiology

authors： Bergey GK,Bigalke H,Nelson PG

更新日期：1987-01-01 00:00:00

abstract：:Two-Photon Processor (TPP) is a versatile, ready-to-use, and freely available software package in MATLAB to process data from in vivo two-photon calcium imaging. TPP includes routines to search for cell bodies in full-frame (Search for Neural Cells Accelerated; SeNeCA) and line-scan acquisition, routines for calcium s...

journal_title：Journal of neurophysiology

authors： Tomek J,Novak O,Syka J

更新日期：2013-07-01 00:00:00

abstract：:Ifenprodil is a selective blocker of NMDA receptors that are heterodimers composed of GluN1/GluN2B subunits. This pharmacological profile has been extensively used to test the role of GluN2B-containing NMDA receptors in learning and memory formation. However, ifenprodil has also been reported to have actions at a numb...

journal_title：Journal of neurophysiology

authors： Delaney AJ,Power JM,Sah P

更新日期：2012-03-01 00:00:00

abstract：:An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded...

journal_title：Journal of neurophysiology

authors： Compte A,Constantinidis C,Tegner J,Raghavachari S,Chafee MV,Goldman-Rakic PS,Wang XJ

更新日期：2003-11-01 00:00:00

abstract：:Many rapidly firing neurons, including those in the medial nucleus of the trapezoid body (MNTB) in the auditory brain stem, express "high threshold" voltage-gated Kv3.1 potassium channels that activate only at positive potentials and are required for stimuli to generate rapid trains of actions potentials. We now descr...

journal_title：Journal of neurophysiology

authors： Brown MR,El-Hassar L,Zhang Y,Alvaro G,Large CH,Kaczmarek LK

更新日期：2016-07-01 00:00:00

abstract：:1. Inhibitors of extracellular carbonic anhydrase (CAo) offer much promise as diagnostic tools in the study of the synaptic basis of activity-induced alkaline transients in the brain. However, most of the present information related to the effects of CAo blockers in nervous tissue comes from experiments that involve s...

journal_title：Journal of neurophysiology

authors： Voipio J,Paalasmaa P,Taira T,Kaila K

更新日期：1995-08-01 00:00:00

abstract：:Fine flexible wire microelectrodes chronically implanted in the fifth lumbar ventral root (L5 VR) of 17 cats rendered stable records of the natural discharge patterns of 164 individual axons during locomotion on a treadmill. Fifty-one out of 164 axons were identified as motoneurons projecting to the anterior thigh mus...

journal_title：Journal of neurophysiology

authors： Hoffer JA,Loeb GE,Marks WB,O'Donovan MJ,Pratt CA,Sugano N

更新日期：1987-02-01 00:00:00

abstract：:Current-clamp recordings were made from the deep cerebellar nuclei (DCN) of 12- to 15-day-old rats to understand the factors that mediate intrinsic spontaneous firing patterns. All of the cells recorded were spontaneously active with spiking patterns ranging continuously from regular spiking to spontaneous bursting wi...

journal_title：Journal of neurophysiology

authors： Aizenman CD,Linden DJ

更新日期：1999-10-01 00:00:00

abstract：:Many neurons within prefrontal cortex exhibit a tonic discharge between visual stimulation and motor response. This delay activity may contribute to movement, memory, and vision. We studied delay activity sent from the frontal eye field (FEF) in prefrontal cortex to the superior colliculus (SC). We evaluated whether t...

journal_title：Journal of neurophysiology

authors： Sommer MA,Wurtz RH

更新日期：2001-04-01 00:00:00

abstract：:Responses have been recorded from primary endings of muscle spindles in the cat soleus muscle. Changes in spindle responsiveness were measured following a period of conditioning that consisted of a series of rapid stretches or of tetanic ventral root stimulation. In the testing procedure the response of a single spind...

journal_title：Journal of neurophysiology

authors： Gregory JE,Morgan DL,Proske U

更新日期：1986-08-01 00:00:00

abstract：:Locusts have two large collision-detecting neurons, the descending contralateral movement detectors (DCMDs) that signal object approach and trigger evasive glides during flight. We sought to investigate whether vision for action, when the locust is in an aroused state rather than a passive viewer, significantly alters...

journal_title：Journal of neurophysiology

authors： Rind FC,Santer RD,Wright GA

更新日期：2008-08-01 00:00:00

abstract：:Fast oscillatory activity (more than approximately 200 Hz) has been attracting increasing attention regarding its possible role in both normal brain function and epileptogenesis. Yet, its underlying cellular mechanism remains poorly understood. Our prior investigation of the phenomenon in rat somatosensory cortex indi...

journal_title：Journal of neurophysiology

authors： Jones MS,Barth DS

更新日期：2002-08-01 00:00:00

abstract：:1. The transmission in the spinal monosynaptic pathway was studied during repetitive stimulation of a motor nerve by 10 stimuli at 2, 5, or 10 Hz in spinal cats. Initially, the amplitudes of the monosynaptic responses rapidly declined, reaching a plateau after a few stimuli. The level of the plateau was inversely rela...

journal_title：Journal of neurophysiology

authors： Capek R,Esplin B

更新日期：1977-01-01 00:00:00

abstract：:The intermediate and deep layers of the monkey superior colliculus (SC) are known to be important for the generation of saccadic eye movements. Recent studies have also provided evidence that the rostral SC might be involved in the control of pursuit eye movements. However, because rostral SC neurons respond to visual...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ

更新日期：2001-11-01 00:00:00

abstract：:Twenty-four slowly adapting type 1 (SA1) and 26 rapidly adapting (RA) cutaneous mechanoreceptive afferents in the rhesus monkey were studied with an array of independently controlled, punctate probes that covered an entire fingerpad. Each afferent had a receptive field (RF) on a single fingerpad and was studied at 73 ...

journal_title：Journal of neurophysiology

authors： Vega-Bermudez F,Johnson KO

更新日期：1999-06-01 00:00:00

abstract：:1. Areas of cerebellar cortex related to saccadic eye movements were ablated in three Macaca mulatta monkeys trained to fixate visual targets. There followed a postoperative dysmetria of saccadic eye movements which appeared to be the result of an impairment specifically within the saccadic system. 2. Convergent evide...

journal_title：Journal of neurophysiology

authors： Ritchie L

更新日期：1976-11-01 00:00:00

abstract：:These experiments were designed to test the hypothesis that climbing fiber inputs evoked by a peripheral stimulus increase the responsiveness of Purkinje cells to mossy fiber inputs. This hypothesis was based on a previous series of observations demonstrating that spontaneous climbing fiber inputs are associated with ...

journal_title：Journal of neurophysiology

authors： Ebner TJ,Yu QX,Bloedel JR

更新日期：1983-07-01 00:00:00

abstract：:Stretch reflexes contribute to arm impedance and longer-latency stretch reflexes exhibit increased sensitivity during interactions with compliant or unstable environments. This increased sensitivity is consistent with a regulation of arm impedance to compensate for decreased stability of the environment, but the speci...

journal_title：Journal of neurophysiology

authors： Krutky MA,Ravichandran VJ,Trumbower RD,Perreault EJ

更新日期：2010-01-01 00:00:00

abstract：:Monocular deprivation (MD) during the critical period for the development of visual cortex causes a loss of binocular response of neurons and a shift to the open eye, a normal ocular dominance (OD) shift. However, when MD is combined with chronic inactivation of the visual cortex by muscimol, the OD distribution of th...

journal_title：Journal of neurophysiology

authors： Shimegi S,Fischer QS,Yang Y,Sato H,Daw NW

更新日期：2003-12-01 00:00:00

abstract：:The CNS controls reproduction through pulsatile secretion of gonadotropin-releasing hormone (GnRH). Episodic increases in the firing rate of unidentified hypothalamic neurons have been associated with downstream markers of GnRH secretion. Whether this episodic electrical activity is intrinsic to GnRH neurons, intrinsi...

journal_title：Journal of neurophysiology

authors： Nunemaker CS,DeFazio RA,Geusz ME,Herzog ED,Pitts GR,Moenter SM

更新日期：2001-07-01 00:00:00

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:Action observation activates brain regions involved in sensory-motor control. Recent research has shown that action observation can also facilitate motor learning; observing a tutor undergoing motor learning results in functional plasticity within the motor system and gains in subsequent motor performance. However, th...

journal_title：Journal of neurophysiology

authors： McGregor HR,Cashaback JGA,Gribble PL

更新日期：2018-12-01 00:00:00

abstract：:Arrays of closely spaced quartz-insulated, platinum-tungsten microelectrodes are widely used to obtain acute recordings from chronically prepared subjects. These electrodes have excellent recording characteristics and can be fabricated to a wide variety of tip specifications. Typically, in such experiments, electrodes...

journal_title：Journal of neurophysiology

authors： Swadlow HA,Bereshpolova Y,Bezdudnaya T,Cano M,Stoelzel CR

更新日期：2005-05-01 00:00:00

abstract：:1. Whole-cell patch-clamp recordings of excitatory postsynaptic currents (EPSCs) were made from guinea pig hippocampal CA1 pyramidal cells. The sensitivity of paired pulse facilitation (PPF) and EPSC variance to changes in synaptic transmission was investigated and the results were compared with the changes in these p...

journal_title：Journal of neurophysiology

authors： Manabe T,Wyllie DJ,Perkel DJ,Nicoll RA

更新日期：1993-10-01 00:00:00

abstract：:Cold-sensitive and nociceptive neural pathways interact to shape the quality and intensity of thermal and pain perception. Yet the central processing of cold thermosensation in the human brain has not been extensively studied. Here, we used magnetoencephalography and EEG in healthy volunteers to investigate the time c...

journal_title：Journal of neurophysiology

authors： Fardo F,Vinding MC,Allen M,Jensen TS,Finnerup NB

更新日期：2017-05-01 00:00:00

abstract：:Rhythm generation by the gastric motor network in the stomatogastric ganglion (STG) of the lobster Homarus gammarus is controlled by modulatory projection neurons from rostral commissural ganglia (CoGs); blocking action potential conduction in these inputs to the STG of a stomatogastric nervous system in vitro rapidly...

journal_title：Journal of neurophysiology

authors： Faumont S,Simmers J,Meyrand P

更新日期：1998-11-01 00:00:00

abstract：:Recent studies have shown that the initial responses evoked by a stimulus in neurons of primary visual cortex are dominated by low spatial frequency information in the image, whereas finer spatial scales dominate later in the response. Such phenomena could arise from the dynamics of receptive field (RF) size at early ...

journal_title：Journal of neurophysiology

authors： Malone BJ,Kumar VR,Ringach DL

更新日期：2007-01-01 00:00:00