Pathophysiology of affective disorders: functional interaction of stress hormones and hippocampal excitation.

abstract：:Targeting the melanin-concentrating hormone (MCH) system has been suggested as a potential treatment for obesity, anxiety disorders, as well as addiction. Despite the therapeutic potential of MCH agonists and antagonists, the endogenous factors regulating MCH activity, in particular those implicated in anxiety and rew...

journal_title：Journal of neurophysiology

authors： Parsons MP,Hirasawa M

更新日期：2011-03-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:Unitary discharge patterns (peristimulus time histograms or PSTH) and synaptic events were studies with intracellular recording techniques in 164 cat cochlear nucleus cells to steady-frequency tone bursts 250 ms in duration. There were four response types defined on the basis of the shape of the discharge patterns to ...

journal_title：Journal of neurophysiology

authors： Britt R,Starr A

更新日期：1976-01-01 00:00:00

abstract：:Spatiotemporal convergence and two-dimensional (2-D) neural tuning have been proposed as a major neural mechanism in the signal processing of linear acceleration. To examine this hypothesis, we studied the firing properties of primary otolith afferents and central otolith neurons that respond exclusively to horizontal...

journal_title：Journal of neurophysiology

authors： Angelaki DE,Dickman JD

更新日期：2000-10-01 00:00:00

abstract：:1. Ionic conductances controlled by type A and type B cholecystokinin (CCK) receptors were studied in neurons of the rat nucleus tractus solitarius (NTS) and dorsal motor nucleus of the vagus (DMNV), using intracellular and whole-cell patch clamp recordings in current or voltage clamp configuration during bath applica...

journal_title：Journal of neurophysiology

authors： Branchereau P,Champagnat J,Denavit-Saubié M

更新日期：1993-12-01 00:00:00

abstract：:1. The alignment of the pupillary axes and of the visual axes has been measured in 23 normally reared cats ranging in age from 14 days to adulthood. 2. In agreement with a previous report, we find that pupillary divergence, as measured from photographs, tends to decrease during the first 2 mo of life. 3. The angle bet...

journal_title：Journal of neurophysiology

authors： Olson CR,Freeman RD

更新日期：1978-07-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:Distinguishing which of the many proposed neural mechanisms of spatial attention actually underlies behavioral improvements in visually guided tasks has been difficult. One attractive hypothesis is that attention allows downstream neural circuits to selectively integrate responses from the most informative sensory neu...

journal_title：Journal of neurophysiology

authors： Masse NY,Herrington TM,Cook EP

更新日期：2012-09-01 00:00:00

abstract：:We simultaneously compared the sensitivity of single primary afferent neurons supplying the glabrous skin of the hand and the psychophysical amplitude discrimination thresholds in human subjects for a set of vibrotactile stimuli delivered to the receptive field. All recorded afferents had a dynamic range narrower than...

journal_title：Journal of neurophysiology

authors： Arabzadeh E,Clifford CW,Harris JA,Mahns DA,Macefield VG,Birznieks I

更新日期：2014-11-15 00:00:00

abstract：:This study considers the possibility of using coherence analysis for detection and measurement of synchrony (correlations) in large neural populations, applied to activities that are relatively easy to record in parallel. Mathematical analysis and computer simulations are used to examine the behavior of the coherence ...

journal_title：Journal of neurophysiology

authors： Christakos CN

更新日期：1997-12-01 00:00:00

abstract：:A quantitative analysis of activity-related calcium dynamics was performed in motoneurons of the nucleus hypoglossus in the brain stem slice preparation from mouse by simultaneous patch-clamp and microfluorometric calcium measurements. Motoneurons were analyzed under in vitro conditions that kept them in a functionall...

journal_title：Journal of neurophysiology

authors： Lips MB,Keller BU

更新日期：1999-12-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:Two-Photon Processor (TPP) is a versatile, ready-to-use, and freely available software package in MATLAB to process data from in vivo two-photon calcium imaging. TPP includes routines to search for cell bodies in full-frame (Search for Neural Cells Accelerated; SeNeCA) and line-scan acquisition, routines for calcium s...

journal_title：Journal of neurophysiology

authors： Tomek J,Novak O,Syka J

更新日期：2013-07-01 00:00:00

abstract：:Hypercapnia-induced arousal from sleep is an important protective mechanism pertinent to a number of diseases. Most notably among these are the sudden infant death syndrome, obstructive sleep apnea and sudden unexpected death in epilepsy. Serotonin (5-HT) plays a significant role in hypercapnia-induced arousal. The me...

journal_title：Journal of neurophysiology

authors： Buchanan GF,Smith HR,MacAskill A,Richerson GB

更新日期：2015-07-01 00:00:00

abstract：:High-frequency stimulation (HFS) is used to treat a variety of neurological diseases, yet its underlying therapeutic action is not fully elucidated. Previously, we reported that HFS-induced elevation in [K(+)](e) or bath perfusion of raised K(e)(+) depressed rat entopeduncular nucleus (EP) neuronal activity via an enh...

journal_title：Journal of neurophysiology

authors： Shin DS,Carlen PL

更新日期：2008-05-01 00:00:00

abstract：:Neurons in the silkmoth antennal lobe (AL) are well characterized in terms of their morphology and odor-evoked firing activity. However, their intrinsic electrical properties including voltage-gated ionic currents and synaptic connectivity remain unclear. To address this, whole cell current- and voltage-clamp recordin...

journal_title：Journal of neurophysiology

authors： Tabuchi M,Dong L,Inoue S,Namiki S,Sakurai T,Nakatani K,Kanzaki R

更新日期：2015-11-01 00:00:00

abstract：:Previous studies have described maturational changes in GABAergic inhibitory synaptic transmission in the rodent somatosensory cortex during the early postnatal period. To determine whether alterations in the functional properties of synaptically localized GABA(A) receptors (GABA(A)Rs) contribute to development of inh...

journal_title：Journal of neurophysiology

authors： Dunning DD,Hoover CL,Soltesz I,Smith MA,O'Dowd DK

更新日期：1999-12-01 00:00:00

abstract：:1. The role of the structures of the outer ear in producing monaural and binaural spectral cues to sound location was examined acoustically in the ferret. A probe microphone was introduced across the wall of the external auditory canal and its responses to digitally constructed wideband signals were recorded for a lar...

journal_title：Journal of neurophysiology

authors： Carlile S,King AJ

更新日期：1994-02-01 00:00:00

abstract：:Many critically ill patients in intensive care units suffer from an infection-induced whole body inflammatory state known as sepsis, which causes severe weakness in patients who survive. The mechanisms by which sepsis triggers intensive care unit-acquired weakness (ICUAW) remain unclear. Currently, research into ICUAW...

journal_title：Journal of neurophysiology

authors： Nardelli P,Khan J,Powers R,Cope TC,Rich MM

更新日期：2013-04-01 00:00:00

abstract：:Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Tobler PN,Taira M,Iijima T,Tsutsui K

更新日期：2009-06-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:1. Several heart interneurons (HN cells) of the leech nerve cord have impulse-initiation sites in every segmental ganglion through which their single axons pass. All these initiation sites are capable of producing rhythmic impulse bursts. However, under normal conditions a dominant primary initiation site in the gangl...

journal_title：Journal of neurophysiology

authors： Calabrese RL

更新日期：1980-11-01 00:00:00

abstract：:Two forms of undulatory locomotion in the lamprey (a lower vertebrate) have been described earlier: fast forward swimming (FFS) used for long distance migrations and slow backward swimming (SBS) used for escape from adverse tactile stimuli. In the present study, we describe another form of escape behavior: slow forwar...

journal_title：Journal of neurophysiology

authors： Islam SS,Zelenin PV

更新日期：2008-01-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:When an object is lifted vertically, the normal force increases and decreases in tandem with tangential (load) force to safely avoid slips. For horizontal object transport, horizontal forces at the contact surfaces can be decomposed into manipulation forces (producing acceleration/deceleration) and grasping forces. Al...

journal_title：Journal of neurophysiology

authors： Winges SA,Soechting JF,Flanders M

更新日期：2007-08-01 00:00:00

abstract：:The dorsal premotor area (PMd) of monkeys has been implicated in processes relating to movement preparation and movement selection. In the present study, we sought to determine whether PMd neurons that are activated during a delayed reaching task have directional responses that reflect either the target (i.e., the goa...

journal_title：Journal of neurophysiology

authors： Shen L,Alexander GE

更新日期：1997-03-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:We studied the effect of eye position on visual and pursuit-related activity in neurons in the superior temporal sulcus of the macaque monkey. Altogether, 109 neurons from the middle temporal area (area MT) and the medial superior temporal area (area MST) were tested for influence of eye position on their stimulus-dri...

journal_title：Journal of neurophysiology

authors： Bremmer F,Ilg UJ,Thiele A,Distler C,Hoffmann KP

更新日期：1997-02-01 00:00:00

abstract：:1. The spatial and temporal response characteristics of direction-selective neurons in the nucleus of the optic tract and dorsal terminal nucleus of the accessory optic system (NOT-DTN) of the wallaby were established using moving sinusoidal gratings. This is the first comprehensive investigation of the spatiotemporal...

journal_title：Journal of neurophysiology

authors： Ibbotson MR,Mark RF,Maddess TL

更新日期：1994-12-01 00:00:00