Pathophysiology of affective disorders: functional interaction of stress hormones and hippocampal excitation.

abstract：:In adults, locomotor movements are accommodated to various support surface conditions by means of specific anticipatory locomotor adjustments and changes in the intersegmental coordination. Here we studied the kinematic strategies of toddlers at the onset of independent walking when negotiating various support surface...

journal_title：Journal of neurophysiology

authors： Dominici N,Ivanenko YP,Cappellini G,Zampagni ML,Lacquaniti F

更新日期：2010-03-01 00:00:00

abstract：:1. Recent immunocytochemical and receptor binding data have demonstrated a transient somatotopic patterning of serotonin (5-HT)-immunoreactive fibers in the primary somatosensory cortex of developing rats and a transient expression of 5-HT1B receptors on thalamocortical axons from the ventral posteromedial thalamic nu...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Bennett-Clarke CA,Shi MY,Mooney RD

更新日期：1994-11-01 00:00:00

abstract：:Bis(7)-tacrine is a potent acetylcholinesterase inhibitor in which two tacrine molecules are linked by a heptylene chain. We tested the effects of bis(7)-tacrine on the spontaneous synaptic activity. Miniature endplate potentials (MEPPs) were recorded extracellularly on slices of electric organ of Torpedo marmorata. B...

journal_title：Journal of neurophysiology

authors： Ros E,Aleu J,Gomez de Aranda I,Cantí C,Pang YP,Marsal J,Solsona C

更新日期：2001-07-01 00:00:00

abstract：:Adaptation to novel dynamics requires learning a motor memory, or a new pattern of predictive feedforward motor commands. Recently, we demonstrated the upregulation of rapid visuomotor feedback gains early in curl force field learning, which decrease once a predictive motor memory is learned. However, even after learn...

journal_title：Journal of neurophysiology

authors： Franklin S,Wolpert DM,Franklin DW

更新日期：2017-11-01 00:00:00

abstract：:In this study we attempted to identify the principles that govern the changes in neural control that occur during repeated performance of a multiarticular coordination task. Eight participants produced isometric flexion/extension and pronation/supination torques at the radiohumeral joint, either in isolation (e.g., fl...

journal_title：Journal of neurophysiology

authors： Shemmell J,Forner M,Tresilian JR,Riek S,Barry BK,Carson RG

更新日期：2005-11-01 00:00:00

abstract：:1. Horizontal cells were enzymatically and mechanically dissociated from the white perch (Roccus americana) retina and voltage clamped using patch electrodes. Steady-state current-voltage (I-V) relationships of solitary horizontal cells were determined by changing the membrane potential in a rampwise fashion. 2. The I...

journal_title：Journal of neurophysiology

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1988-10-01 00:00:00

abstract：:Most of what we know about the neural control of gaze comes from experiments in head-fixed animals, but several "head-free" studies have suggested that fixing the head dramatically alters the apparent gaze command. We directly investigated this issue by quantitatively comparing head-fixed and head-free gaze trajectori...

journal_title：Journal of neurophysiology

authors： Martinez-Trujillo JC,Klier EM,Wang H,Crawford JD

更新日期：2003-10-01 00:00:00

abstract：:Foot drop is very common among people with chronic incomplete spinal cord injury (SCI) and likely stems from SCI that disturbs the corticospinal activation of the ankle dorsiflexor tibialis anterior (TA). Thus, if one can recover or increase the corticospinal excitability reduced by SCI, motor function recovery may be...

journal_title：Journal of neurophysiology

authors： Thompson AK,Fiorenza G,Smyth L,Favale B,Brangaccio J,Sniffen J

更新日期：2019-03-01 00:00:00

abstract：:A seizure-paralysis repertoire characteristic of Drosophila "bang-sensitive" mutants can be evoked electroconvulsively in tethered flies, in which behavioral episodes are associated with synchronized spike discharges in different body parts. Flight muscle DLMs (dorsal longitudinal muscles) display a stereotypic sequen...

journal_title：Journal of neurophysiology

authors： Lee J,Wu CF

更新日期：2006-11-01 00:00:00

abstract：:1. The present study was designed to determine the effects of microstimulation of the medullary reticular formation (MRF) on the locomotor activity of the cat in the absence of phasic afferent feedback from the limbs. To this end, both short (33 ms) and long (200 ms) trains of stimuli (trains of 0.2-ms pulses at 330 H...

journal_title：Journal of neurophysiology

authors： Perreault MC,Rossignol S,Drew T

更新日期：1994-01-01 00:00:00

abstract：:Studying adaptation to Coriolis perturbations of arm movements has advanced our understanding of motor control and learning. We have now applied this paradigm to two-dimensional postural sway. We measured how subjects (n = 8) standing at the center of a fully enclosed rotating room who made voluntary anterior-posterio...

journal_title：Journal of neurophysiology

authors： Bakshi A,DiZio P,Lackner JR

更新日期：2019-06-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:Long-term potentiation (LTP) in rat spinal dorsal horn neurons was induced by electrical high-frequency stimulation (HFS) of afferent C fibers. LTP is generally assumed to be a key mechanism of spinal sensitization. To determine the contribution of skin and muscle afferents to LTP induction, the sural nerve (SU, pure ...

journal_title：Journal of neurophysiology

authors： Zhang J,Hoheisel U,Klein T,Magerl W,Mense S,Treede RD

更新日期：2016-02-01 00:00:00

abstract：:Action potential firing rates are generally limited by the refractory period, which depends on the recovery from inactivation of voltage-gated Na channels. In cerebellar Purkinje neurons, the kinetics of Na channels appear specialized for rapid firing. Upon depolarization, an endogenous open-channel blocker rapidly te...

journal_title：Journal of neurophysiology

authors： Afshari FS,Ptak K,Khaliq ZM,Grieco TM,Slater NT,McCrimmon DR,Raman IM

更新日期：2004-11-01 00:00:00

abstract：:Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence of contextual details. There are indications that recollection, familiarity, and novelty involve different medial temporal lobe ...

journal_title：Journal of neurophysiology

authors： Daselaar SM,Fleck MS,Cabeza R

更新日期：2006-10-01 00:00:00

abstract：:Bladder and erectile dysfunction are common urologic complications of diabetes and are associated with reduced parasympathetic autonomic control. To determine whether disruption of ganglionic neurotransmission contributes to the loss of function, we investigated synaptic transmission at parasympathetic, major pelvic g...

journal_title：Journal of neurophysiology

authors： Tompkins JD,Vizzard MA,Parsons RL

更新日期：2013-02-01 00:00:00

abstract：:The marine mollusk Clione limacina, when swimming, can stabilize different body orientations in the gravitational field. The stabilization is based on the reflexes initiated by activation of the statocyst receptor cells and mediated by the cerebro-pedal interneurons that produce excitation of the motoneurons of the ef...

journal_title：Journal of neurophysiology

authors： Deliagina TG,Orlovsky GN,Selverston AI,Arshavsky YI

更新日期：2000-01-01 00:00:00

abstract：:1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...

journal_title：Journal of neurophysiology

authors： Sakai HM,Naka K

更新日期：1987-12-01 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:1. In alpha-chloralose-anesthetized cats the region surrounding the ventral posterolateral nucleus (VPL) of the thalamus was investigated to locate foci with input from the urinary bladder stimulated by application of intravesical pressure. The locations of the recording sites were verified in Nissl-stained histologic...

journal_title：Journal of neurophysiology

authors： Brüggemann J,Vahle-Hinz C,Kniffki KD

更新日期：1993-08-01 00:00:00

abstract：:N-methyl-d-aspartate (NMDA) receptors play crucial roles in glutamate-mediated synaptic transmission and plasticity and are involved in a variety of brain functions. Specific single nucleotide polymorphisms (SNPs) in the genes encoding NMDA receptor subunits have been associated with some neuropsychiatric disorders in...

journal_title：Journal of neurophysiology

authors： Mori F,Ribolsi M,Kusayanagi H,Siracusano A,Mantovani V,Marasco E,Bernardi G,Centonze D

更新日期：2011-10-01 00:00:00

abstract：:This study examined whether neuronal activity in the dorsal premotor cortex (PMd) covaries with image motion or actual movement of the arm while planning a target-capturing task when the motor task is guided by an image of the moving arm. For this purpose, we trained a monkey to capture a target on a video screen with...

journal_title：Journal of neurophysiology

authors： Ochiai T,Mushiake H,Tanji J

更新日期：2002-10-01 00:00:00

abstract：:Intracellular recording from lumbar motoneurons and extracellular recording from ventral roots of the neonatal rat isolated spinal cord were used to study the mechanisms responsible for the excitation mediated by NK3 tachykinin receptors. The selective NK3 agonists senktide or [MePhe7]neurokinin B induced a slow depol...

journal_title：Journal of neurophysiology

authors： Marchetti C,Nistri A

更新日期：2001-12-01 00:00:00

abstract：:While the cochlear implant has successfully restored hearing to many deaf patients, it cannot benefit those without a functional auditory nerve or an implantable cochlea. As an alternative, the auditory midbrain implant (AMI) has been developed and implanted into deaf patients. Consisting of a single-shank array, the ...

journal_title：Journal of neurophysiology

authors： Straka MM,Schendel D,Lim HH

更新日期：2013-08-01 00:00:00

abstract：:Extracellular discharges from single neurons in the internal segment of the globus pallidus (GPi) were recorded and analyzed for rate changes associated with visually guided forearm rotations to four different targets. We sought to examine how GPi neurons contribute to movement preparation and execution. Unit discharg...

journal_title：Journal of neurophysiology

authors： Gdowski MJ,Miller LE,Parrish T,Nenonene EK,Houk JC

更新日期：2001-02-01 00:00:00

abstract：:Substance P (SP) hyperpolarizes approximately 80% of ferret vagal sensory neurons (nodose ganglion neurons) via NK-1 receptor-mediated activation of a potassium current (IK). A depolarizing current activated by membrane hyperpolarization could minimize the SP-induced hyperpolarization. Such a current exists in 65% of ...

journal_title：Journal of neurophysiology

authors： Jafri MS,Weinreich D

更新日期：1998-02-01 00:00:00

abstract：:Stretch reflexes contribute to arm impedance and longer-latency stretch reflexes exhibit increased sensitivity during interactions with compliant or unstable environments. This increased sensitivity is consistent with a regulation of arm impedance to compensate for decreased stability of the environment, but the speci...

journal_title：Journal of neurophysiology

authors： Krutky MA,Ravichandran VJ,Trumbower RD,Perreault EJ

更新日期：2010-01-01 00:00:00

abstract：:The anterior branch of N. VIII was sectioned in adult frogs. Two months later the brain was isolated to record in vitro responses in the vestibular nuclei and from the abducens nerves following electric stimulation of the anterior branch of N. VIII or of the posterior canal nerve. Extra- and intracellularly recorded r...

journal_title：Journal of neurophysiology

authors： Goto F,Straka H,Dieringer N

更新日期：2000-07-01 00:00:00

abstract：:Cutaneous reflexes evoked in the muscles of the arms with electrical stimulation of nerves of the foot ("interlimb reflexes") are observed during walking. These reflexes have been suggested to coordinate the actions of the legs and arms when walking is disturbed. Recently, we showed that cutaneous reflexes evoked in t...

journal_title：Journal of neurophysiology

authors： Haridas C,Zehr EP,Misiaszek JE

更新日期：2006-12-01 00:00:00

abstract：:The role of voltage-dependent calcium channels (VDCCs) in the nicotinic acetylcholine receptor (nAChR)-mediated enhancement of spontaneous GABAergic inhibitory postsynaptic currents (IPSCs) was investigated in chick brain slices. Whole cell recordings of neurons in the lateral spiriform (SpL) and ventral lateral genic...

journal_title：Journal of neurophysiology

authors： Tredway TL,Guo JZ,Chiappinelli VA

更新日期：1999-02-01 00:00:00