Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ.

abstract：:We investigated whether the proprioceptive eye position signal after the execution of a saccadic eye movement is used to estimate the accuracy of the movement. If so, saccadic adaptation, the mechanism that maintains saccade accuracy, could use this signal in a similar way as it uses visual feedback after the saccade....

journal_title：Journal of neurophysiology

authors： Gremmler S,Lappe M

更新日期：2019-11-01 00:00:00

abstract：:Understanding how whisker-based tactile information is represented in the nervous system requires quantification of sensory input and observation of neural activity during whisking and whisker touch. Chronic electrophysiological methods have long been available to study neural responses in awake and behaving animals; ...

journal_title：Journal of neurophysiology

authors： Voigts J,Sakmann B,Celikel T

更新日期：2008-07-01 00:00:00

abstract：:Echolocating bats use echoes of their sonar emissions to determine the position and distance of objects or prey. Target distance is represented as a map of echo delay in the auditory cortex (AC) of bats. During a bat's flight through a natural complex environment, echo streams are reflected from multiple objects along...

journal_title：Journal of neurophysiology

authors： Greiter W,Firzlaff U

更新日期：2017-06-01 00:00:00

abstract：:Single-channel recording techniques were used to characterize mechanosensitive channels in identified (1.1'-dioctadecyl-3,3,3', 3'-tetramethylindocarbocyanine methanesulfonate labeled) colon sensory neurons dissociated from adult S1 dorsal root ganglia. Channels were found in 30% (7/23) of patches in a cell-attached c...

journal_title：Journal of neurophysiology

authors： Su X,Wachtel RE,Gebhart GF

更新日期：2000-08-01 00:00:00

abstract：:Speech stimuli give rise to neural activity in the listener that can be observed as waveforms using magnetoencephalography. Although waveforms vary greatly from trial to trial due to activity unrelated to the stimulus, it has been demonstrated that spoken sentences can be discriminated based on theta-band (3-7 Hz) pha...

journal_title：Journal of neurophysiology

authors： Howard MF,Poeppel D

更新日期：2010-11-01 00:00:00

abstract：:We recorded local field potentials (LFPs) and single-unit activity simultaneously in the macaque primary visual cortex (V1) and studied their responses to drifting sinusoidal gratings that were chosen to be "optimal" for the single units. Over all stimulus conditions, the LFP spectra have much greater power in the low...

journal_title：Journal of neurophysiology

authors： Henrie JA,Shapley R

更新日期：2005-07-01 00:00:00

abstract：:In quadrupeds, the dorsal-side-up body orientation during standing is maintained due to a postural system that is driven by feedback signals coming mainly from limb mechanoreceptors. In caudally decerebrated (postmammillary) rabbits, the efficacy of this system is considerably reduced. In this paper, we report that th...

journal_title：Journal of neurophysiology

authors： Zelenin PV,Hsu LJ,Orlovsky GN,Deliagina TG

更新日期：2012-06-01 00:00:00

abstract：:1. The onset of visual activity in the superficial layers of the cat superior colliculus begins abruptly at about 6 days postnatal (DPN), just before natural eye opening. Despite the presence of many inactive sites at this time, the systematic nature of the superior colliculus visuotopy is already evident. The number ...

journal_title：Journal of neurophysiology

authors： Kao CQ,McHaffie JG,Meredith MA,Stein BE

更新日期：1994-07-01 00:00:00

abstract：:The increasing use of transgenic mice for the study of pain mechanisms necessitates comprehensive understanding of the murine somatosensory system. Using an in vivo mouse preparation, we studied response properties of tibial nerve afferent fibers innervating glabrous skin. Recordings were obtained from 225 fibers iden...

journal_title：Journal of neurophysiology

authors： Cain DM,Khasabov SG,Simone DA

更新日期：2001-04-01 00:00:00

abstract：:Thalamic relay neurons express high levels of T-type Ca(2+) channels, which support the generation of robust burst discharges. This intrinsically mediated form of phasic spike firing is thought to be critical in the generation of slow (3-4 Hz) synchronous oscillatory activity of absence epilepsy. Recordings made from ...

journal_title：Journal of neurophysiology

authors： Porcello DM,Smith SD,Huguenard JR

更新日期：2003-01-01 00:00:00

abstract：:We studied gamma-aminobutyric acid (GABA)-mediated currents in short-term cultured dorsal unpaired median (DUM) neurons of cockroach Periplaneta americana using the whole cell patch-clamp technique in symmetrical chloride solutions. All DUM neurons voltage-clamped at -50 mV displayed inward currents (I(GABA)) when 10(...

journal_title：Journal of neurophysiology

authors： Alix P,Grolleau F,Hue B

更新日期：2002-06-01 00:00:00

abstract：:Trimming all whiskers except two on one side of an adult rat's face results in cortical plasticity in which the spared whiskers, D2 and one D-row surround whisker (either D1 or D3), evoked responses containing more spikes than the response evoked by the cut whisker (called whisker pairing plasticity). Previously we ha...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Egli M,Stonecypher M,Wiley RG,Ebner FF

更新日期：2000-10-01 00:00:00

abstract：:Dopamine neurons in freely moving rats often fire behaviorally relevant high-frequency bursts, but depolarization block limits the maximum steady firing rate of dopamine neurons in vitro to ∼10 Hz. Using a reduced model that faithfully reproduces the sodium current measured in these neurons, we show that adding an add...

journal_title：Journal of neurophysiology

authors： Qian K,Yu N,Tucker KR,Levitan ES,Canavier CC

更新日期：2014-12-01 00:00:00

abstract：:This study considers the possibility of using coherence analysis for detection and measurement of synchrony (correlations) in large neural populations, applied to activities that are relatively easy to record in parallel. Mathematical analysis and computer simulations are used to examine the behavior of the coherence ...

journal_title：Journal of neurophysiology

authors： Christakos CN

更新日期：1997-12-01 00:00:00

abstract：:Stretch reflexes contribute to arm impedance and longer-latency stretch reflexes exhibit increased sensitivity during interactions with compliant or unstable environments. This increased sensitivity is consistent with a regulation of arm impedance to compensate for decreased stability of the environment, but the speci...

journal_title：Journal of neurophysiology

authors： Krutky MA,Ravichandran VJ,Trumbower RD,Perreault EJ

更新日期：2010-01-01 00:00:00

abstract：:Motoneurons receive synaptic inputs from tens of thousands of connections that cause membrane potential to fluctuate continuously (synaptic noise), which introduces variability in discharge times of action potentials. We hypothesized that the influence of synaptic noise on force steadiness during voluntary contraction...

journal_title：Journal of neurophysiology

authors： Dideriksen JL,Negro F,Enoka RM,Farina D

更新日期：2012-06-01 00:00:00

abstract：:1. We recorded from 257 neurons in the banks of the posterior third of the principal sulcus of two rhesus monkeys trained to look at a fixation point and make saccades to stimuli in the visual periphery. Sixty-six percent (220/257) discharged or were suppressed in association with one or more aspects of the tasks we u...

journal_title：Journal of neurophysiology

authors： Boch RA,Goldberg ME

更新日期：1989-05-01 00:00:00

abstract：:The brain stem nucleus locus coeruleus (LC) is thought to modulate cortical excitability by norepinephrine (NE) release in LC forebrain targets. The effects of LC burst discharge, typically evoked by a strong excitatory input, on cortical ongoing activity are poorly understood. To address this question, we combined di...

journal_title：Journal of neurophysiology

authors： Marzo A,Totah NK,Neves RM,Logothetis NK,Eschenko O

更新日期：2014-06-15 00:00:00

abstract：:Microstimulation within the motor regions of the spinal cord is often assumed to activate motoneurons and propriospinal neurons close to the electrode tip. However, previous work has shown that intraspinal microstimulation (ISMS) in the gray matter activates sensory afferent axons as well as alpha-motoneurons (MNs). H...

journal_title：Journal of neurophysiology

authors： Gaunt RA,Prochazka A,Mushahwar VK,Guevremont L,Ellaway PH

更新日期：2006-12-01 00:00:00

abstract：:In the region of the ventral respiratory group in brain stem slices from neonatal rats, intracellular pH (pHi) and membrane currents (I(m)) or potentials were measured in neurons dialyzed with the pH-sensitive dye 2',7'-bis-carboxyethyl-5(6)-carboxyfluorescein. Currents and increases in membrane conductance (g(m)) dur...

journal_title：Journal of neurophysiology

authors： Lückermann M,Trapp S,Ballanyi K

更新日期：1997-04-01 00:00:00

abstract：:In the main olfactory bulb, several populations of granule cells (GCs) can be distinguished based on the soma location either superficially, interspersed with mitral cells within the mitral cell layer (MCL), or deeper, within the GC layer (GCL). Little is known about the physiological properties of superficial GCs (sG...

journal_title：Journal of neurophysiology

authors： Heinbockel T,Hamilton KA,Ennis M

更新日期：2007-04-01 00:00:00

abstract：:The essential role of calcium in the induction of long-term potentiation (LTP) has been well established. In particular, calcium influx via the N-methyl-D-aspartate (NMDA) receptor (NMDAR) is important for LTP induction in many pathways. However, the specific roles of other calcium sources in hippocampal LTP are less ...

journal_title：Journal of neurophysiology

authors： Raymond CR,Redman SJ

更新日期：2002-07-01 00:00:00

abstract：:Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational model of a ventral striatal MSN, we simulated whole cell D1- and D2-receptor-mediated modulation of both intrinsic (sodium, calcium, and potassium...

journal_title：Journal of neurophysiology

authors： Moyer JT,Wolf JA,Finkel LH

更新日期：2007-12-01 00:00:00

abstract：:When a monkey attends to, remembers, and looks toward targets, the activity of some neurons in the lateral intraparietal area (LIP) changes. We recorded from isolated neurons during both a spatial and a shape match-to-sample task to examine and characterize voluntary active processes in LIP. Many LIP neurons show spat...

journal_title：Journal of neurophysiology

authors： Sereno AB,Amador SC

更新日期：2006-02-01 00:00:00

abstract：:Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their ...

journal_title：Journal of neurophysiology

authors： Sturm JJ,Weisz CJ

更新日期：2015-11-01 00:00:00

abstract：:Intracellular recording from lumbar motoneurons and extracellular recording from ventral roots of the neonatal rat isolated spinal cord were used to study the mechanisms responsible for the excitation mediated by NK3 tachykinin receptors. The selective NK3 agonists senktide or [MePhe7]neurokinin B induced a slow depol...

journal_title：Journal of neurophysiology

authors： Marchetti C,Nistri A

更新日期：2001-12-01 00:00:00

abstract：:The vestibuloocular reflex (VOR) needs to modulate its gain depending on target distance to prevent retinal slip during head movements. We investigated gain modulation (context compensation) for binocular gaze stabilization in human subjects during voluntary yaw and pitch head rotations. Movements of each eye were rec...

journal_title：Journal of neurophysiology

authors： Medendorp WP,Van Gisbergen JA,Van Pelt S,Gielen CC

更新日期：2000-12-01 00:00:00

abstract：:The function of the ventral nucleus of the lateral lemniscus (VNLL), a secondary processing site within the auditory brain stem, is unclear. It is known to be a major source of inhibition to the inferior colliculus (IC). It is also thought to play a role in coding the temporal aspects of sound, such as onsets and the ...

journal_title：Journal of neurophysiology

authors： Nayagam DA,Clarey JC,Paolini AG

更新日期：2005-08-01 00:00:00

abstract：:In acute experiments performed in decerebrated and spinalized (T13) cats, an intraspinal injection of clonidine, a noradrenergic agonist, restricted to mid-lumbar segments L3-L4, can induce hindlimb locomotion, whereas yohimbine, a noradrenergic antagonist, can block spinal locomotion, and a second spinal lesion at L4...

journal_title：Journal of neurophysiology

authors： Langlet C,Leblond H,Rossignol S

更新日期：2005-05-01 00:00:00

abstract：:Children do not typically appear to move with the same skill and dexterity as adults, although they can still improve their motor performance in specific tasks with practice. One possible explanation is that their motor performance is limited by an inherently higher level of movement variability, but that their motor ...

journal_title：Journal of neurophysiology

authors： Takahashi CD,Nemet D,Rose-Gottron CM,Larson JK,Cooper DM,Reinkensmeyer DJ

更新日期：2003-08-01 00:00:00