Operant conditioning of the motor-evoked potential and locomotion in people with and without chronic incomplete spinal cord injury.

abstract：:Animals are adapted to respond quickly to threats in their environment. In many invertebrate and some vertebrate species, the evolutionary pressures have resulted in rapidly conducting giant axons, which allow short response times. Although neural circuits mediating escape behavior are identified in several species, l...

journal_title：Journal of neurophysiology

authors： Mullins OJ,Hackett JT,Friesen WO

更新日期：2011-01-01 00:00:00

abstract：:1. Both stretch and release of the ventral superficial muscles (VSM) in the abdomen of the hermit crab, Pagurus pollicarus, activate the VSM motoneurons in the intact animal and in the isolated abdomen. 2. This reflex was studied by recording intracellularly from muscle fibers innervated by single motoneurons during s...

journal_title：Journal of neurophysiology

authors： Chapple WD

更新日期：1993-06-01 00:00:00

abstract：:Patch clamp is the main technique for measuring electrical properties of individual cells. Since its discovery in 1976 by Neher and Sakmann, patch clamp has been instrumental in broadening our understanding of the fundamental properties of ion channels and synapses in neurons. The conventional patch-clamp method requi...

journal_title：Journal of neurophysiology

authors： Wu 吴秋雨 Q,Kolb I,Callahan BM,Su Z,Stoy W,Kodandaramaiah SB,Neve R,Zeng H,Boyden ES,Forest CR,Chubykin AA

更新日期：2016-10-01 00:00:00

abstract：:Neurons display a variety of complex dendritic morphologies even within the same class. We examined the relationship between dendritic arborization and the coupling between somatic and dendritic action potential (AP) initiation sites in layer 5 (L5) neocortical pyramidal neurons. Coupling was defined as the relative r...

journal_title：Journal of neurophysiology

authors： Schaefer AT,Larkum ME,Sakmann B,Roth A

更新日期：2003-06-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:1. The responses of a total of 70 single neurons were recorded from the parabrachial nuclei (PBN) in awake rats. In 59 neurons, sapid stimuli (0.5 ml) elicited significant taste responses. Of these 59 neurons, 10 also had significant responses to water. The mean spontaneous rate of the taste neurons was 13.4 +/- 6.9 (...

journal_title：Journal of neurophysiology

authors： Nishijo H,Norgren R

更新日期：1990-04-01 00:00:00

abstract：:Electrophysiological analysis has revealed much about the broad coding and neural ensemble dynamics that characterize gustatory cortical (GC) taste processing in awake rats and about how these dynamics relate to behavior. With regard to mice, however, data concerning cortical taste coding have largely been restricted ...

journal_title：Journal of neurophysiology

authors： Levitan D,Lin JY,Wachutka J,Mukherjee N,Nelson SB,Katz DB

更新日期：2019-10-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:Corneal-responsive neurons were recorded extracellularly in two regions of the spinal trigeminal nucleus, subnucleus interpolaris/caudalis (Vi/Vc) and subnucleus caudalis/upper cervical cord (Vc/C1) transition regions, from methohexital-anesthetized male rats. Thirty-nine Vi/Vc and 26 Vc/C1 neurons that responded to m...

journal_title：Journal of neurophysiology

authors： Hirata H,Hu JW,Bereiter DA

更新日期：1999-11-01 00:00:00

abstract：:1. Neuronal activity was recorded from the premotor cortex (PM) of Japanese monkeys while they performed hand movements with different amplitudes and directions. On each behavioral trial, two instructions were given sequentially: 1) an amplitude instruction (large or small) and 2) a direction instruction (flexion or e...

journal_title：Journal of neurophysiology

authors： Kurata K

更新日期：1993-01-01 00:00:00

abstract：:The vestibuloocular reflex (VOR) needs to modulate its gain depending on target distance to prevent retinal slip during head movements. We investigated gain modulation (context compensation) for binocular gaze stabilization in human subjects during voluntary yaw and pitch head rotations. Movements of each eye were rec...

journal_title：Journal of neurophysiology

authors： Medendorp WP,Van Gisbergen JA,Van Pelt S,Gielen CC

更新日期：2000-12-01 00:00:00

abstract：:The same set of stimuli and analytic methods that was used to study the dynamics of horizontal cells () was applied to a study of the response dynamics and signal processing in amacrine cells in the retina of the kissing gourami, Helostoma rudolfi. The retina contains two major classes of amacrine cells that could be ...

journal_title：Journal of neurophysiology

authors： Sakai HM,Machuca H,Naka KI

更新日期：1997-10-01 00:00:00

abstract：:1. In the intact pond snail Planorbis corneus, a rapid tilt in any plane evoked a defense reaction consisting of a fast movement of the shell towards the head, shortening of the foot, inhibition of locomotion and of rhythmical feeding movements. This reaction was similar to the first phase of the general defense react...

journal_title：Journal of neurophysiology

authors： Arshavsky YI,Deliagina TG,Okshtein IL,Orlovsky GN,Panchin YV,Popova LB

更新日期：1994-03-01 00:00:00

abstract：:Behavioral performance in detection and discrimination tasks is likely to be limited by the quality and nature of the signals carried by populations of neurons in early sensory cortical areas. Here we used voltage-sensitive dye imaging (VSDI) to directly measure neural population responses in the primary visual cortex...

journal_title：Journal of neurophysiology

authors： Chen Y,Geisler WS,Seidemann E

更新日期：2008-03-01 00:00:00

abstract：:Through their actions in the nucleus accumbens (NAc), kappa opioid (KOP) receptors and their endogenous ligand, dynorphin, modify behaviors associated with the administration of drugs of abuse and are regulated by exposure to such drugs. Despite their demonstrated behavioral significance, the synaptic actions of KOP r...

journal_title：Journal of neurophysiology

authors： Hjelmstad GO,Fields HL

更新日期：2003-05-01 00:00:00

abstract：:1. The physiological and pharmacological properties of excitatory amino acid (EAA)-induced responses were investigated in acutely isolated spiral ganglion cells of guinea pig by a conventional patch-clamp technique combined with a rapid drug application (Y-tube) method. 2. L-glutamate (Glu) and its agonists, quisquala...

journal_title：Journal of neurophysiology

authors： Nakagawa T,Komune S,Uemura T,Akaike N

更新日期：1991-03-01 00:00:00

abstract：:We investigated the precision of spike timing in a model of gap junction-coupled oscillatory neurons. The model incorporated the known physiology, morphology, and connectivity of the weakly electric fish's high-frequency and extremely precise pacemaker nucleus (Pn). Two neuron classes, pacemaker and relay cells, were ...

journal_title：Journal of neurophysiology

authors： Moortgat KT,Bullock TH,Sejnowski TJ

更新日期：2000-02-01 00:00:00

abstract：:1. The responses of onset units in the cochlear nucleus of the anesthetized guinea pig have been measured to single tones, two-tone complexes, and broadband noise (BBN; 20-kHz bandwidth). The onset units were subdivided into three groups, onset-I (OnI), onset-L (OnL), and onset-C (OnC), on the basis of a decision tree...

journal_title：Journal of neurophysiology

authors： Winter IM,Palmer AR

更新日期：1995-01-01 00:00:00

abstract：:This study investigated the influence of different modalities of target information (visual, kinesthetic) on the accuracy, kinematics, and interjoint coordination of pointing movements to remembered targets. The targets were presented by a robot arm in five locations in three-dimensional (3D) space, either as a point ...

journal_title：Journal of neurophysiology

authors： Adamovich SV,Berkinblit MB,Fookson O,Poizner H

更新日期：1998-06-01 00:00:00

abstract：:The experiments described in this report were designed to determine the contribution of vestibulospinal neurons (VSNs) in Deiters' nucleus and of reticulospinal neurons (RSNs) in the medullary reticular formation to the modifications of the walking pattern that are associated with locomotion on an inclined plane. Neur...

journal_title：Journal of neurophysiology

authors： Matsuyama K,Drew T

更新日期：2000-11-01 00:00:00

abstract：:This study investigated the organization of the dorsal lateral geniculate nucleus (LGN) of the tree shrew (Tupaia glis) using both microelectrode recording and anatomical techniques. The tree shrew LGN contains approximately 100,000 cells, of which 20% are in layers 2 and 6. These two layers receive input from the ips...

journal_title：Journal of neurophysiology

authors： Conway JL,Schiller PH

更新日期：1983-12-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:Human functional magnetic resonance imaging (fMRI) studies, as well as lesion, drug, and single-cell recording studies in animals, suggest that the striatum plays a key role in associating sensory events with rewarding actions, both by facilitating reward processing and prediction (i.e., reinforcement learning) and by...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Seger CA

更新日期：2013-10-01 00:00:00

abstract：:The whole cell patch-clamp technique in combination with the slice preparation was used to investigate the electrophysiological properties of pigeon semicircular canal sensory and supporting cells. These properties were also characterized in regenerating neuroepithelia of pigeons preinjected with streptomycin to kill ...

journal_title：Journal of neurophysiology

authors： Masetto S,Correia MJ

更新日期：1997-10-01 00:00:00

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, is caused by loss of the fragile X mental retardation protein (FMRP). FMRP is a negative regulator of local mRNA translation downstream of group 1 metabotropic glutamate receptor (Gp1 mGluR) activation. In the absence of FMRP there is...

journal_title：Journal of neurophysiology

authors： Auerbach BD,Bear MF

更新日期：2010-08-01 00:00:00

abstract：:Animal studies have suggested that tissue injury-related increased levels of glutamate may be involved in peripheral nociceptive mechanisms in deep craniofacial tissues. Indeed, injection of glutamate (0.1-1 M, 10 microl) into the temporomandibular region evokes reflex jaw muscle responses through activation of periph...

journal_title：Journal of neurophysiology

authors： Cairns BE,Hu JW,Arendt-Nielsen L,Sessle BJ,Svensson P

更新日期：2001-08-01 00:00:00

abstract：:Humans adopt very different head movement strategies for different gaze behaviors, for example, when playing sports versus watching sports on television. Such strategy switching appears to depend on both context and expectation of future gaze positions. Here, we explored the neural mechanisms for such behaviors by tra...

journal_title：Journal of neurophysiology

authors： Monteon JA,Avillac M,Yan X,Wang H,Crawford JD

更新日期：2012-11-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the ef...

journal_title：Journal of neurophysiology

authors： Jang HJ,Cho KH,Park SW,Kim MJ,Yoon SH,Rhie DJ

更新日期：2012-01-01 00:00:00

abstract：:1. Effects of substance P (SP) and other tachykinins on membrane currents were investigated using whole cell voltage clamp in cultured sensory neurons isolated from rat dorsal root ganglia. 2. SP (100 nM) evoked an inward current in two-thirds of the cells at negative potentials. In most of the cells that generated th...

journal_title：Journal of neurophysiology

authors： Inoue K,Nakazawa K,Inoue K,Fujimori K

更新日期：1995-02-01 00:00:00