Integration of autopatching with automated pipette and cell detection in vitro.

abstract：:When a thin plastic test strip of various hardness is placed between the upper and lower teeth during rhythmical jaw movements induced by electrical stimulation of the cortical masticatory area (CMA) in anesthetized rabbits, electromyographic (EMG) activity of the masseter muscle is facilitated in a hardness-dependent...

journal_title：Journal of neurophysiology

authors： Komuro A,Morimoto T,Iwata K,Inoue T,Masuda Y,Kato T,Hidaka O

更新日期：2001-12-01 00:00:00

abstract：:We cloned 10 full-length variants of PIIH, the gene for I(h) from the spiny lobster, Panulirus interruptus, using reverse transcription-PCR (RT-PCR) and rapid amplification of cDNA ends (RACE). This gene shows a significant amount of alternative splicing in the S3-S4 and S4-S5 linkers, in the P-loop and the entire S6 ...

journal_title：Journal of neurophysiology

authors： Ouyang Q,Goeritz M,Harris-Warrick RM

更新日期：2007-06-01 00:00:00

abstract：:Evidence for a persistent Na+ current (I(NaP)) in the apical dendrite of neocortical neurons was sought with the use of fluorescence imaging to measure changes in intradendritic Na+ concentration. Neurons in neocortical brain slices were filled iontophoretically through an intracellular recording microelectrode with t...

journal_title：Journal of neurophysiology

authors： Mittmann T,Linton SM,Schwindt P,Crill W

更新日期：1997-08-01 00:00:00

abstract：:Since sensory systems operate with a finite quantity of processing resources, an animal would benefit from prioritizing processing of sensory stimuli within a time window that is expected to provide key information. This behavioral manifestation of such prioritization is known as attention. Here, we investigate attent...

journal_title：Journal of neurophysiology

authors： Lee CCY,Clifford CWG,Arabzadeh E

更新日期：2019-03-01 00:00:00

abstract：:Serotonergic fibers broadly innervate the thalamus and may influence the sleep wake cycle, attention, and other processes through modulation of neurons in this structure. However, the actions of serotonin in the dorsal thalamus have been investigated in detail only in the dorsal lateral geniculate nucleus. In the pres...

journal_title：Journal of neurophysiology

authors： Monckton JE,McCormick DA

更新日期：2002-04-01 00:00:00

abstract：:1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

journal_title：Journal of neurophysiology

authors： Andreasen M,Hablitz JJ

更新日期：1993-06-01 00:00:00

abstract：:1. In taste neurophysiology, from Pfaffmann's (49, 50) pioneering work until the present, the possibility of types of neurons corresponding in some sense with the "primary" taste qualities of Henning (33) has been entertained: recently types of gustatory neurons in peripheral nerves have been established according to ...

journal_title：Journal of neurophysiology

authors： Woolston DC,Erickson RP

更新日期：1979-09-01 00:00:00

abstract：:Formation of local excitatory circuits may contribute to epileptogenesis. We tested the hypothesis that epileptogenesis is associated with increased recurrent excitation in the hippocampal CA1 area of rats with kainate-induced epilepsy. Whole cell recordings were obtained during focal flash photolysis of caged glutama...

journal_title：Journal of neurophysiology

authors： Shao LR,Dudek FE

更新日期：2004-09-01 00:00:00

abstract：:Tinnitus is a phantom auditory perception without an external sound source and is one of the most common public health concerns that impair the quality of life of many individuals. However, its neural mechanisms remain unclear. We herein examined population-level frequency tuning in the auditory cortex of unilateral t...

journal_title：Journal of neurophysiology

authors： Sekiya K,Takahashi M,Murakami S,Kakigi R,Okamoto H

更新日期：2017-03-01 00:00:00

abstract：:Contact-evoked changes in EMG activity during human grasp. 2215 Cutaneous receptors in the digits discharge bursts of activity on contact with an object during human grasp. In this study, we investigated the contribution of this sensory activity to the responses of muscles involved in the task. Twelve subjects perform...

journal_title：Journal of neurophysiology

authors： Collins DF,Knight B,Prochazka A

更新日期：1999-05-01 00:00:00

abstract：:In neuroendocrine cells, hormone release often requires a collective burst of action potentials synchronized by gap junctions. This is the case for the electrically coupled bag cell neurons in the reproductive system of the marine snail, Aplysia californica. These neuroendocrine cells are found in two clusters, and fi...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Colmers PL,Hodgson HM,Magoski NS

更新日期：2014-12-01 00:00:00

abstract：:1. Baclofen increases transient light responses of amacrine and ganglion cells despite acting as a classical inhibitory transmitter to both hyperpolarize and shunt these cells. 2. This effect seems to occur at the level of the inner retina and appears not to be due to an additional input from bipolar cells. 3. In some...

journal_title：Journal of neurophysiology

authors： Bai SH,Slaughter MM

更新日期：1989-02-01 00:00:00

abstract：:Recent advances in recording and computing hardware have enabled laboratories to record the electrical activity of multiple brain regions simultaneously. Lagging behind these technical advances, however, are the methods needed to rapidly produce microdrives and head-caps that can flexibly accommodate different recordi...

journal_title：Journal of neurophysiology

authors： Headley DB,DeLucca MV,Haufler D,Paré D

更新日期：2015-04-01 00:00:00

abstract：:1. The first experiment of this study determined the effects of low-frequency stimulation of the monkey superior colliculus on spontaneous saccades in the dark. Stimulation trains, subthreshold for eliciting short-latency fixed-vector saccades, were highly effective at biasing the metrics (direction and amplitude) of ...

journal_title：Journal of neurophysiology

authors： Glimcher PW,Sparks DL

更新日期：1993-03-01 00:00:00

abstract：:Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, is caused by loss of the fragile X mental retardation protein (FMRP). FMRP is a negative regulator of local mRNA translation downstream of group 1 metabotropic glutamate receptor (Gp1 mGluR) activation. In the absence of FMRP there is...

journal_title：Journal of neurophysiology

authors： Auerbach BD,Bear MF

更新日期：2010-08-01 00:00:00

abstract：:The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...

journal_title：Journal of neurophysiology

authors： Kuroki S,Watanabe J,Nishida S

更新日期：2016-03-01 00:00:00

abstract：:Stroke survivors' difficulty in releasing grasped objects may be attributable not only to impaired finger extension but also to delays in terminating activity in the gripping flexor muscles. This study was undertaken 1) to quantify the time needed to initiate and terminate grip muscular activity following stroke and 2...

journal_title：Journal of neurophysiology

authors： Seo NJ,Rymer WZ,Kamper DG

更新日期：2009-06-01 00:00:00

abstract：:One of the critical factors in determining network behavior of neurons is the influence of local circuit connections among interneurons. The short-term synaptic plasticity and the subtype of presynaptic calcium channels used at local circuit connections of inhibitory interneurons in CA1 were investigated using dual wh...

journal_title：Journal of neurophysiology

authors： Ali AB

更新日期：2011-03-01 00:00:00

abstract：:Eigenmannia, a genus of weakly electric fish, exhibits a specialized behavior known as the jamming avoidance response (JAR). The JAR results in a categorical difference between Eigenmannia that are in groups of conspecifics and those that are alone. Fish in groups exhibit the JAR behavior and thereby experience ongoin...

journal_title：Journal of neurophysiology

authors： Ramcharitar JU,Tan EW,Fortune ES

更新日期：2006-11-01 00:00:00

abstract：:1. The hyperpolarization that follows tetanic stimulation was recorded intra-axonally from the internodal region of intramuscular myelinated motor axons. 2. The peak amplitude of the posttetanic hyperpolarization (PTH) that followed stimulation at 20-100 Hz for < or = 35 s increased with increasing train duration, rea...

journal_title：Journal of neurophysiology

authors： Morita K,David G,Barrett JN,Barrett EF

更新日期：1993-11-01 00:00:00

abstract：:The human ventral visual pathway is implicated in higher order form processing, but the organizational principles within this region are not yet well understood. Recently, Lafer-Sousa, Conway, and Kanwisher (J Neurosci 36: 1682-1697, 2016) used functional magnetic resonance imaging to demonstrate that functional respo...

journal_title：Journal of neurophysiology

authors： Goddard E

更新日期：2017-03-01 00:00:00

abstract：:Spinal neurons undergo large cyclic membrane potential oscillations during fictive locomotion in lamprey. It was investigated whether these oscillations were due only to synaptically driven excitatory and inhibitory potentials or if voltage-dependent inward conductances also contribute to the depolarizing phase by usi...

journal_title：Journal of neurophysiology

authors： Hu GY,Biró Z,Hill RH,Grillner S

更新日期：2002-06-01 00:00:00

abstract：:Intracellular recordings were performed in Cs-loaded sympathetic preganglionic neurons (SPNs) of the intermediolateral nucleus, identified by antidromic stimulation, in the slice of the T2 or T3 segment of the cat spinal cord. Loading the neurons with Cs resulted in broadening of the action potential, depression of th...

journal_title：Journal of neurophysiology

authors： Yoshimura M,Polosa C,Nishi S

更新日期：1987-05-01 00:00:00

abstract：:Gamma-aminobutyric acid type A (GABAA) receptors expressed within the medial preoptic area (mPOA) are known to play a critical role in regulating sexual and neuroendocrine functions. In the rat brain, high levels of expression of the gamma1 subunit mRNA of the GABAA receptor are restricted to a limited number of regio...

journal_title：Journal of neurophysiology

authors： Nett ST,Jorge-Rivera JC,Myers M,Clark AS,Henderson LP

更新日期：1999-01-01 00:00:00

abstract：:Beta-band oscillations are a dominant feature in the sensorimotor system, which includes movement-related beta desynchronization (MRBD) during the preparation and execution phases of movement and postmovement beta synchronization (PMBS) on movement cessation. Many studies have linked this rhythm to motor functions. Ho...

journal_title：Journal of neurophysiology

authors： Zhang X,Li H,Xie T,Liu Y,Chen J,Long J

更新日期：2020-08-01 00:00:00

abstract：:Augmenting (or incremental) responses are progressively growing potentials elicited by 5- to 15-Hz stimulation within the thalamus, cerebral cortex, or by setting into action reciprocal thalamocortical neuronal loops. These responses are associated with short-term plasticity processes in thalamic and cortical neurons....

journal_title：Journal of neurophysiology

authors： Timofeev I,Steriade M

更新日期：1998-05-01 00:00:00

abstract：:Microelectrode studies in monkeys performing short-term memory tasks show the sustained elevated discharge of cortical neurons during the retention of recalled sensory information. Cortical cells that are part of memory networks are assumed to receive numerous inputs of excitatory as well as inhibitory nature and loca...

journal_title：Journal of neurophysiology

authors： Bodner M,Zhou YD,Fuster JM

更新日期：1997-04-01 00:00:00

abstract：:In the present study, we sought to unravel how exploratory movements affect length perception of rods that are held in and wielded by hand. We manipulated the mechanical rod properties--mass (m), first moment of mass distribution (M), major principal moment of inertia (I(1))--individually, allowing us to assess the re...

journal_title：Journal of neurophysiology

authors： Debats NB,van de Langenberg RW,Kingma I,Smeets JB,Beek PJ

更新日期：2010-11-01 00:00:00

abstract：:Action potential firing rates are generally limited by the refractory period, which depends on the recovery from inactivation of voltage-gated Na channels. In cerebellar Purkinje neurons, the kinetics of Na channels appear specialized for rapid firing. Upon depolarization, an endogenous open-channel blocker rapidly te...

journal_title：Journal of neurophysiology

authors： Afshari FS,Ptak K,Khaliq ZM,Grieco TM,Slater NT,McCrimmon DR,Raman IM

更新日期：2004-11-01 00:00:00

abstract：:Primates have a remarkable ability to perceive, recognize, and discriminate among the plethora of people, places, and things that they see, and neural selectivity in the primate inferotemporal (IT) cortex is thought to underlie this ability. Here we investigated the relationship between neural response and perception ...

journal_title：Journal of neurophysiology

authors： Allred S,Liu Y,Jagadeesh B

更新日期：2005-12-01 00:00:00