Genetic modifications of seizure susceptibility and expression by altered excitability in Drosophila Na(+) and K(+) channel mutants.

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, par...

journal_title：Journal of neurophysiology

authors： Mackel R,Miyashita E

更新日期：1993-05-01 00:00:00

abstract：:The synaptic plasticity literature has focused on establishing necessity and sufficiency as two essential and distinct features in causally relating a signaling molecule to plasticity induction, an approach that has been surprisingly lacking in the intrinsic plasticity literature. In this study, we complemented the re...

journal_title：Journal of neurophysiology

authors： Ashhad S,Johnston D,Narayanan R

更新日期：2015-04-01 00:00:00

abstract：:Neocortical circuits exhibit a rich dynamic repertoire, and their ability to achieve entrainment (adjustment of their frequency to match the input frequency) is thought to support many cognitive functions and indicate functional flexibility. Although previous studies have explored the influence of various circuit prop...

journal_title：Journal of neurophysiology

authors： Papasavvas CA,Trevelyan AJ,Kaiser M,Wang Y

更新日期：2020-03-01 00:00:00

abstract：:Ablation and single-unit studies in primates have shown that inferior temporal (IT) cortex is important for pattern discrimination. The first paper in this series suggested that single units in IT cortex of alert monkeys respond to a set of two-dimensional patterns with complex temporal modulation of their spike train...

journal_title：Journal of neurophysiology

authors： Optican LM,Richmond BJ

更新日期：1987-01-01 00:00:00

abstract：:Monitoring representative fractions of neurons from multiple brain circuits in behaving animals is necessary for understanding neuronal computation. Here, we describe a system that allows high-channel-count recordings from a small volume of neuronal tissue using a lightweight signal multiplexing headstage that permits...

journal_title：Journal of neurophysiology

authors： Berényi A,Somogyvári Z,Nagy AJ,Roux L,Long JD,Fujisawa S,Stark E,Leonardo A,Harris TD,Buzsáki G

更新日期：2014-03-01 00:00:00

abstract：:Whole cell voltage-clamp recordings from acutely isolated hippocampal CA1 pyramidal cells from adult guinea pigs were used to evaluate divalent cations as possible blockers of the postexposure current (Ipe). Ipe is a cation current that is triggered by the rise in intracellular Ca2+ concentration that occurs after the...

journal_title：Journal of neurophysiology

authors： Chen QX,Perkins KL,Wong RK

更新日期：1998-02-01 00:00:00

abstract：:Male zebra finches produce a song consisting of a canonical sequence of syllables, learned from a tutor and repeated throughout its adult life. Much of the neural circuitry responsible for this behavior is located in the cortical premotor region HVC (acronym is name). In a recent study from our laboratory, we found th...

journal_title：Journal of neurophysiology

authors： Galvis D,Wu W,Hyson RL,Johnson F,Bertram R

更新日期：2017-08-01 00:00:00

abstract：:The connectivity of large neurons of the nucleus reticularis gigantocellularis (NRGc) in the medullary reticular formation potentially allows both for the integration of stimuli, in several modalities, that would demand immediate action, and for coordinated activation of cortical and motoric activity. We have simultan...

journal_title：Journal of neurophysiology

authors： Martin EM,Pavlides C,Pfaff D

更新日期：2010-05-01 00:00:00

abstract：:This study examined whether neuronal activity in the dorsal premotor cortex (PMd) covaries with image motion or actual movement of the arm while planning a target-capturing task when the motor task is guided by an image of the moving arm. For this purpose, we trained a monkey to capture a target on a video screen with...

journal_title：Journal of neurophysiology

authors： Ochiai T,Mushiake H,Tanji J

更新日期：2002-10-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play an important role in cell survival versus cell death decisions during neuronal development, ischemia, trauma, and epilepsy. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all these conditions. In the developing CN...

journal_title：Journal of neurophysiology

authors： Wang Y,Denisova JV,Kang KS,Fontes JD,Zhu BT,Belousov AB

更新日期：2010-12-01 00:00:00

abstract：:Action potential initiation and conduction along peripheral axons is a dynamic process that displays pronounced activity dependence. In patients with neuropathic pain, differences in the modulation of axonal conduction velocity by activity suggest that this property may provide insight into some of the pathomechanisms...

journal_title：Journal of neurophysiology

authors： Tigerholm J,Petersson ME,Obreja O,Lampert A,Carr R,Schmelz M,Fransén E

更新日期：2014-05-01 00:00:00

abstract：:The hypothesis that gamma-band oscillations are related to the representation of an environmental scene in the cerebral cortex after binding of corresponding perceptual elements is currently under discussion. One question is how the sensory system reacts to a fast change in the scene if perceptual elements are rigidly...

journal_title：Journal of neurophysiology

authors： Ross B,Herdman AT,Pantev C

更新日期：2005-12-01 00:00:00

abstract：:It is well established that orderly patterns of motor neuron activity, muscle recruitment, and limb movement are generated in chicks during motility by embryonic day (E)9, the midpoint in embryonic development. However, our recent work suggests that some attributes of motility, such as the rhythm of repetitive limb mo...

journal_title：Journal of neurophysiology

authors： Bradley NS,Jahng DY

更新日期：2003-09-01 00:00:00

abstract：:A total of 51 dorsal horn units responsive to heat were isolated and their receptive fields characterized (i.e., response properties and adequate stimuli determined) in pentobarbital-anesthetized, paralyzed rats. In 39 of the 51 units, the descending inhibition of heat-evoked activity produced by focal electrical stim...

journal_title：Journal of neurophysiology

authors： Jones SL,Gebhart GF

更新日期：1986-11-01 00:00:00

abstract：:The thalamic reticular nucleus (nRt) provides a major source of inhibition in the thalamo-cortical circuit and is critically involved in the generation of spindle oscillations. Here we describe the properties of thalamic giant depolarizing potentials (tGDPs) that were observed in nRt during early development. tGDPs pe...

journal_title：Journal of neurophysiology

authors： Pangratz-Fuehrer S,Rudolph U,Huguenard JR

更新日期：2007-03-01 00:00:00

abstract：:Mesencephalic trigeminal (M-V) neurons are primary somatosensory neurons with somata located within the CNS, instead of in peripheral sensory ganglia. In amphibians, these unipolar cells are found within the optic tectum and have a single axon that runs along the mandibular branch of the trigeminal nerve. The axon has...

journal_title：Journal of neurophysiology

authors： Pratt KG,Aizenman CD

更新日期：2009-07-01 00:00:00

abstract：:Extracellular acidification induced by retinal horizontal cells has been hypothesized to underlie lateral feedback inhibition onto vertebrate photoreceptors. To test this hypothesis, the H(+)-sensitive fluorophore 5-hexadecanoylaminofluorescein (HAF) was used to measure changes in H(+) from horizontal cells isolated f...

journal_title：Journal of neurophysiology

authors： Jacoby J,Kreitzer MA,Alford S,Malchow RP

更新日期：2014-03-01 00:00:00

abstract：:We analyzed the receptive field information conveyed by interspike intervals (ISIs) in the auditory cortex. In the visual system, different ISIs may both code for different visual features and convey differing amounts of stimulus information. To determine their potential role in auditory signal processing, we obtained...

journal_title：Journal of neurophysiology

authors： Shih JY,Atencio CA,Schreiner CE

更新日期：2011-04-01 00:00:00

abstract：:The discovery that neuroligin is a key protein involved in synapse formation offers the unprecedented opportunity to induce functional synapses between neurons and heterologous cells. We took this opportunity recording for the first-time synaptic currents in human embryonic kidney 293 (HEK293) cells transfected with n...

journal_title：Journal of neurophysiology

authors： Fu Z,Washbourne P,Ortinski P,Vicini S

更新日期：2003-12-01 00:00:00

abstract：:It has been suggested that successively presented sounds that are perceived as separate auditory streams are represented by separate populations of neurons. Mostly, spectral separation in different peripheral filters has been identified as the cue for segregation. However, stream segregation based on temporal cues is ...

journal_title：Journal of neurophysiology

authors： Itatani N,Klump GM

更新日期：2011-01-01 00:00:00

abstract：:1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

journal_title：Journal of neurophysiology

authors： Blum KI,Idiart MA

更新日期：1994-09-01 00:00:00

abstract：:Although frequency-dependent short-term presynaptic plasticity has been of long-standing interest, most studies have emphasized modulation of the synchronous, phasic component of transmitter release, most evident with a single or a few presynaptic stimuli. Asynchronous transmitter release, vesicle fusion not closely t...

journal_title：Journal of neurophysiology

authors： Chang CY,Mennerick S

更新日期：2010-01-01 00:00:00

abstract：:The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exp...

journal_title：Journal of neurophysiology

authors： Xu J,Yu L,Stanford TR,Rowland BA,Stein BE

更新日期：2015-02-01 00:00:00

abstract：:1. The synaptic pathways underlying tectal influence over pinna movements were studied using an acute electrophysiological approach. Under pentobarbital anesthesia, postsynaptic potentials were recorded intracellularly in antidromically identified, cat facial motoneurons following electrical stimulation of the superio...

journal_title：Journal of neurophysiology

authors： Vidal PP,May PJ,Baker R

更新日期：1988-08-01 00:00:00

abstract：:Cutaneous application of painful radiant heat laser pulses evokes potentials (laser-evoked potentials) that can be recorded from scalp or intracranial electrodes. We have now tested the hypothesis that the response of thalamic neurons to a cutaneous laser stimulus occurs at latencies predicted by the conduction delay ...

journal_title：Journal of neurophysiology

authors： Kobayashi K,Winberry J,Liu CC,Treede RD,Lenz FA

更新日期：2009-05-01 00:00:00

abstract：:In sensory systems, the thalamus has historically been considered a relay station. Neural representations of temporal modulations in the auditory system undergo considerable changes as they pass from the inferior colliculus (IC) to the auditory cortex. We sought to determine in awake primates the extent to which audit...

journal_title：Journal of neurophysiology

authors： Bartlett EL,Wang X

更新日期：2007-02-01 00:00:00

abstract：:1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

journal_title：Journal of neurophysiology

authors： McClellan AD

更新日期：1994-08-01 00:00:00

abstract：:The rhythmic delivery of visual stimuli evokes large-scale neuronal entrainment in the form of steady-state oscillatory field potentials. The spatiotemporal properties of stimulus drive appear to constrain the relative degrees of neuronal entrainment. Specific frequency ranges, for example, are uniquely suited for enh...

journal_title：Journal of neurophysiology

authors： Nguyen T,Kuntzelman K,Miskovic V

更新日期：2017-07-01 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) is increasingly used to modify brain activity noninvasively and to study brain-behavior relations. However, results can be variable and the conditions that affect the functional efficacy of TMS remain unclear. Here we show that on-line TMS can either facilitate or suppress perce...

journal_title：Journal of neurophysiology

authors： Silvanto J,Cattaneo Z,Battelli L,Pascual-Leone A

更新日期：2008-05-01 00:00:00