Genetic variants of the NMDA receptor influence cortical excitability and plasticity in humans.

abstract：:To examine the mechanisms underlying milk-ejection bursts of oxytocin (OT) neurons during suckling, both in vivo and in vitro studies were performed on supraoptic OT neurons from lactating rats. The bursts were first recorded extracellularly in anesthetized rats. Burst-related electrical parameters were essentially th...

journal_title：Journal of neurophysiology

authors： Wang YF,Hatton GI

更新日期：2004-05-01 00:00:00

abstract：:Neurons in both the lateral intraparietal area (LIP) of the monkey parietal cortex and the intermediate layers of the superior colliculus (SC) are activated well in advance of the initiation of saccadic eye movements. To determine whether there is a progression in the covert processing for saccades from area LIP to SC...

journal_title：Journal of neurophysiology

authors： Paré M,Wurtz RH

更新日期：2001-06-01 00:00:00

abstract：:A seizure-paralysis repertoire characteristic of Drosophila "bang-sensitive" mutants can be evoked electroconvulsively in tethered flies, in which behavioral episodes are associated with synchronized spike discharges in different body parts. Flight muscle DLMs (dorsal longitudinal muscles) display a stereotypic sequen...

journal_title：Journal of neurophysiology

authors： Lee J,Wu CF

更新日期：2006-11-01 00:00:00

abstract：:We used the framework of the uncontrolled manifold (UCM) hypothesis to explore changes in the structure of variability in multifinger force-production tasks when a secondary task was introduced. Healthy young subjects produced several levels of the total force by pressing with the four fingers of the hand on force sen...

journal_title：Journal of neurophysiology

authors： Zhang W,Scholz JP,Zatsiorsky VM,Latash ML

更新日期：2008-02-01 00:00:00

abstract：:The R6/2 mouse is the most frequently used model for experimental and preclinical drug trials in Huntington's disease (HD). When the R6/2 mouse was first developed, it carried exon 1 of the huntingtin gene with ~150 cytosine-adenine-guanine (CAG) repeats. The model presented with a rapid and aggressive phenotype that ...

journal_title：Journal of neurophysiology

authors： Cummings DM,Alaghband Y,Hickey MA,Joshi PR,Hong SC,Zhu C,Ando TK,André VM,Cepeda C,Watson JB,Levine MS

更新日期：2012-01-01 00:00:00

abstract：:Efficient sensory coding implies that populations of neurons should represent information-rich aspects of a signal with little redundancy. Recent studies have shown that neural heterogeneity in higher brain areas enhances the efficiency of encoding by reducing redundancy across the population. Here, we study how neura...

journal_title：Journal of neurophysiology

authors： Marsat G,Maler L

更新日期：2010-11-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:The reward value of a stimulus can be learned through two distinct mechanisms: reinforcement learning through repeated stimulus-reward pairings and abstract inference based on knowledge of the task at hand. The reinforcement mechanism is often identified with midbrain dopamine neurons. Here we show that a neural pathw...

journal_title：Journal of neurophysiology

authors： Bromberg-Martin ES,Matsumoto M,Hong S,Hikosaka O

更新日期：2010-08-01 00:00:00

abstract：:Altered activity of the entopeduncular nucleus, the rodent homologue of the globus pallidus internal segment in primates, is thought to mediate behavioral consequences of midbrain dopamine depletion in rodents. Few studies, however, have examined dopaminergic modulation of spiking activity in this nucleus. This study ...

journal_title：Journal of neurophysiology

authors： Ruskin DN,Bergstrom DA,Walters JR

更新日期：2002-07-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:Two of the biggest health problems facing us today are addiction to nicotine and the increased prevalence of obesity. Interestingly, nicotine attenuates obesity, but the underlying mechanism is not clear. Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomel...

journal_title：Journal of neurophysiology

authors： Huang H,Xu Y,van den Pol AN

更新日期：2011-09-01 00:00:00

abstract：:Formation of local excitatory circuits may contribute to epileptogenesis. We tested the hypothesis that epileptogenesis is associated with increased recurrent excitation in the hippocampal CA1 area of rats with kainate-induced epilepsy. Whole cell recordings were obtained during focal flash photolysis of caged glutama...

journal_title：Journal of neurophysiology

authors： Shao LR,Dudek FE

更新日期：2004-09-01 00:00:00

abstract：:Lower limb paralysis from spinal cord injury (SCI) or neurological disease carries a poor prognosis for recovery and remains a large societal burden. Neurophysiological and neuroprosthetic research have the potential to improve quality of life for these patients; however, the lack of an ethical and sustainable nonhuma...

journal_title：Journal of neurophysiology

authors： Krucoff MO,Zhuang K,MacLeod D,Yin A,Byun YW,Manson RJ,Turner DA,Oliveira L,Lebedev MA

更新日期：2017-09-01 00:00:00

abstract：:1. Pharmacologic agents known to modulate long-term potentiation (LTP) at the mossy fiber-to-CA3 pyramidal neuron synapse were tested for their effects on the activity of single voltage-gated calcium channels in adult CA3 pyramidal neurons. 2. Single-channel current recordings of three types of voltage-gated calcium c...

journal_title：Journal of neurophysiology

authors： Fisher R,Johnston D

更新日期：1990-10-01 00:00:00

abstract：:Locusts have two large collision-detecting neurons, the descending contralateral movement detectors (DCMDs) that signal object approach and trigger evasive glides during flight. We sought to investigate whether vision for action, when the locust is in an aroused state rather than a passive viewer, significantly alters...

journal_title：Journal of neurophysiology

authors： Rind FC,Santer RD,Wright GA

更新日期：2008-08-01 00:00:00

abstract：:The responses of many neurons in primary visual cortex are modulated by stimuli outside the classical receptive field in ways that may contribute to integrative processes like scene segmentation. To explore this issue, single-unit neuronal responses were recorded in monkey cortical areas V1 and V2 to visual stimuli co...

journal_title：Journal of neurophysiology

authors： Marcus DS,Van Essen DC

更新日期：2002-11-01 00:00:00

abstract：:Adult rats were submitted to a complete spinal cord transection at T9 level to address peripheral and spinal reflex changes in the caudal lumbar segments. Compound muscle and nerve action potentials decreased in amplitude and increased their duration between 14 and 30 days but recovered to near to normal values therea...

journal_title：Journal of neurophysiology

authors： Valero-Cabré A,Forés J,Navarro X

更新日期：2004-06-01 00:00:00

abstract：:Membrane-permeable arachidonic acid (AA) is liberated in a Ca2+-dependent way inside cells. By using whole cell patch clamp we show that intracellular AA (1 pM) selectively reduces IA in rat hippocampal neurons, whereas extracellular application requires a 10(6)-fold concentration. The nonmetabolized AA analogue ETYA ...

journal_title：Journal of neurophysiology

authors： Bittner K,Müller W

更新日期：1999-07-01 00:00:00

abstract：:Feedback control of our limbs must account for the unexpected offset of mechanical perturbations. Here we examine the evoked activity of elbow flexor and extensor muscles to torque pulses lasting 22-152 ms and how torque offset impacts activity in the long-latency (45-100 ms) and voluntary epochs (120-180 ms). For eac...

journal_title：Journal of neurophysiology

authors： Kurtzer I,Pruszynski JA,Scott SH

更新日期：2010-06-01 00:00:00

abstract：:Recent studies have shown that sympathetic nervous system (SNS) activity can be heavily impacted not only by basic threats to survival but also by threats to social bonds. In this study we explored the behavioral and physiological consequences of social exclusion/inclusion in patients with psoriasis, a disease frequen...

journal_title：Journal of neurophysiology

authors： Ponsi G,Monachesi B,Panasiti V,Aglioti SM,Panasiti MS

更新日期：2019-01-01 00:00:00

abstract：:If a laterally displacing prism is placed in front of one eye of a person or monkey with the other eye occluded, they initially will point to one side of a target that is located directly in front of them. Normally, people and monkeys adapt easily to the displaced vision and correct their aim after a few trials. If th...

journal_title：Journal of neurophysiology

authors： Baizer JS,Kralj-Hans I,Glickstein M

更新日期：1999-04-01 00:00:00

abstract：:Many have recently questioned whether all levels of actions understanding, from lower kinematic levels to the higher goal or intention levels of action understanding, are processed in the action observation network (a network of neurons that are active during action execution and observation). A recent study by Wurm a...

journal_title：Journal of neurophysiology

authors： Marneweck M,Vallence AM

更新日期：2016-03-01 00:00:00

abstract：:Previous studies have rarely tested whether the activity of high-frequency discharge (HFD) neurons of the basal ganglia (BG) is modulated by expectation, delivery, and omission of aversive events. Therefore the full value domain encoded by the BG network is still unknown. We studied the activity of HFD neurons of the ...

journal_title：Journal of neurophysiology

authors： Joshua M,Adler A,Rosin B,Vaadia E,Bergman H

更新日期：2009-02-01 00:00:00

abstract：:The ability of a spatial population of cutaneous, Adelta, and C mechano-nociceptors to encode the location and intensity of a noxious, cutaneous indentation was examined using an isolated preparation in a rat model. Skin and its intact innervation were harvested from the medial thigh of the rat hindlimb and placed in ...

journal_title：Journal of neurophysiology

authors： Khalsa PS,Zhang C,Qin YX

更新日期：2000-05-01 00:00:00

abstract：:Contrasting theories of visual attention have emphasized selection by spatial location, individual features, and whole objects. We used functional magnetic resonance imaging to ask whether and how attention to one feature of an object spreads to other features of the same object. Subjects viewed two spatially superimp...

journal_title：Journal of neurophysiology

authors： Ernst ZR,Boynton GM,Jazayeri M

更新日期：2013-11-01 00:00:00

abstract：:Dorsal root afferent depolarization and antidromic firing were studied in isolated spinal cords of neonatal rats. Spontaneous firing accompanied by occasional bursts could be recorded from most dorsal roots in the majority of the cords. The afferent bursts were enhanced after elevation of the extracellular potassium c...

journal_title：Journal of neurophysiology

authors： Kremer E,Lev-Tov A

更新日期：1998-05-01 00:00:00

abstract：:Exposure to odorants results in a rapid (<10 s) reduction in odor-evoked activity in the rat piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To further understand this form of cortical plasticity, a detailed analysis of its odor specificity was performed. Habituation of o...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-01-01 00:00:00

abstract：:Acetic acid applied to the hind limb of a frog evokes nocifensive behaviors, including a vigorous wiping of the exposed skin, referred to as the wiping response. The aim of this study was to examine the responses of cutaneous primary afferent fibers in frogs to acetic acid (pH 2.84-1.42) applied topically to the skin....

journal_title：Journal of neurophysiology

authors： Hamamoto DT,Simone DA

更新日期：2003-08-01 00:00:00

abstract：:Paw-shake responses (PSRs) were evoked by wrapping masking tape around the hind-paw in nine cats spinalized at the T12 level either at 2 or 12 wk of age or as young adults (10-12 mo). Electromyographic responses of ankle extensors (LG and SOL) and one ankle flexor (TA) were recorded through the 6th mo after cord trans...

journal_title：Journal of neurophysiology

authors： Sabin C,Smith JL

更新日期：1984-04-01 00:00:00

abstract：:1. The capacity for judging the location of an object relative to the body (egocentric localization) was assessed in cats by measuring the landing position attained when the cat jumped toward a platform viewed from a known distance. 2. Normal cats and kittens land at center of the platform when using one eye or both. ...

journal_title：Journal of neurophysiology

authors： Olson CR

更新日期：1980-03-01 00:00:00