A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.

abstract：:1. To better characterize temporal and spatial mechanisms involved in the coding of prolonged nociceptive stimuli in the spinal cord, the responses of dorsal horn wide dynamic range (WDR) and nociceptive-specific (NS) neurons to prolonged, repetitive noxious heat stimuli (45-49 degrees C) were examined in unanesthetiz...

journal_title：Journal of neurophysiology

authors： Coghill RC,Mayer DJ,Price DD

更新日期：1993-03-01 00:00:00

abstract：:We investigated the topography of human cortical activation during an antisaccade task by focal transcranial magnetic stimulation (TMS). We used a figure-eight shaped coil, with the stimulus intensity set just above the threshold for activation of the hand motor areas but weak enough not to elicit blinks. TMS was deli...

journal_title：Journal of neurophysiology

authors： Terao Y,Fukuda H,Ugawa Y,Hikosaka O,Hanajima R,Furubayashi T,Sakai K,Miyauchi S,Sasaki Y,Kanazawa I

更新日期：1998-08-01 00:00:00

abstract：:1. The role of the structures of the outer ear in producing monaural and binaural spectral cues to sound location was examined acoustically in the ferret. A probe microphone was introduced across the wall of the external auditory canal and its responses to digitally constructed wideband signals were recorded for a lar...

journal_title：Journal of neurophysiology

authors： Carlile S,King AJ

更新日期：1994-02-01 00:00:00

abstract：:The aim of this study was to investigate how maximal intermittent contractions for a hand muscle influence cortical and reflex activity, as well as the ability to voluntarily activate, the homologous muscle in the opposite limb. Twelve healthy subjects (age: 24 ± 3 years, all right hand dominant) performed maximal con...

journal_title：Journal of neurophysiology

authors： Kavanagh JJ,Feldman MR,Simmonds MJ

更新日期：2016-11-01 00:00:00

abstract：:In many rhythmic neuronal networks that operate in a wide range of frequencies, the time of neuronal firing relative to the cycle period (the phase) is invariant. This invariance suggests that when frequency changes, firing time is precisely adjusted either by intrinsic or synaptic mechanisms. We study the maintenance...

journal_title：Journal of neurophysiology

authors： Manor Y,Bose A,Booth V,Nadim F

更新日期：2003-11-01 00:00:00

abstract：:1. In chronically prepared, freely moving rats, electrical stimulation was applied to the angular bundle, and responses were recorded extracellularly at a variety of sites in the ipsilateral hippocampal formation. At each recording site the stimulus-response relationship was tested during four different behavioral sta...

journal_title：Journal of neurophysiology

authors： Winson J,Abzug C

更新日期：1978-05-01 00:00:00

abstract：:The α9-nicotinic acetylcholine receptor (α9-nAChR) subunit is expressed in the vestibular and auditory periphery, and its loss of function could compromise peripheral input from the predominantly cholinergic efferent vestibular system (EVS). A recent study has shown that α9-nAChRs play an important role in short-term ...

journal_title：Journal of neurophysiology

authors： Hübner PP,Khan SI,Migliaccio AA

更新日期：2017-04-01 00:00:00

abstract：:Capacitance measurements allow direct studies of exocytosis and endocytosis in single synaptic terminals isolated from bipolar neurons of goldfish retina. Extending the technique to intact bipolar cells, with their more complex morphology, requires information about the cells' electrotonic architecture. To this end, w...

journal_title：Journal of neurophysiology

authors： Mennerick S,Zenisek D,Matthews G

更新日期：1997-07-01 00:00:00

abstract：:We previously showed that, when observers watch an actor performing a predictable block-stacking task, the coordination between the observer's gaze and the actor's hand is similar to the coordination between the actor's gaze and hand. Both the observer and the actor direct gaze to forthcoming grasp and block landing s...

journal_title：Journal of neurophysiology

authors： Rotman G,Troje NF,Johansson RS,Flanagan JR

更新日期：2006-09-01 00:00:00

abstract：:Single-unit recordings were made from layer II/III anterior piriform cortex (aPCX) neurons in adult Wistar rats to examine odor response patterns to unilaterally and bilaterally delivered stimuli. Isoamyl acetate odor stimulation was presented either unilaterally through tubes inserted into the external nares, or bila...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：1997-07-01 00:00:00

abstract：:Noninvasive alternating current stimulation can induce vision restoration in patients with chronic optic nerve damage and results in electroencephalogram (EEG) aftereffects. To better understand the mechanisms of action, we studied such EEG "aftereffects" of transcorneal alternating current stimulation (tACS) at the c...

journal_title：Journal of neurophysiology

authors： Sergeeva EG,Fedorov AB,Henrich-Noack P,Sabel BA

更新日期：2012-11-01 00:00:00

abstract：:Following stepping in-place on the surface of a rotating circular treadmill, a subject attempting to step in-place or walk in a straight line across the floor without vision will rotate relative to space. This adaptation, termed podokinetic after-rotation (PKAR), transfers to backward walking following forward walking...

journal_title：Journal of neurophysiology

authors： Earhart GM,Melvill Jones G,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2002-02-01 00:00:00

abstract：:Phasic and tonic motor neurons of crustaceans differ strikingly in their junctional synaptic physiology. Tonic neurons generally produce small excitatory postsynaptic potentials (EPSPs) that facilitate strongly as stimulation frequency is increased, and normally show no synaptic depression. In contrast, phasic neurons...

journal_title：Journal of neurophysiology

authors： Nguyen PV,Marin L,Atwood HL

更新日期：1997-07-01 00:00:00

abstract：:Sciatic nerve section (axotomy) increases the excitability of rat dorsal root ganglion (DRG) neurons. The changes in Ca2+ currents, K+ currents, Ca2+ sensitive K+ current, and hyperpolarization-activated cation current (I(H)) that may be associated with this effect were examined by whole cell recording. Axotomy affect...

journal_title：Journal of neurophysiology

authors： Abdulla FA,Smith PA

更新日期：2001-02-01 00:00:00

abstract：:The Wilson-Cowan population model of neural activity has greatly influenced our understanding of the mechanisms for the generation of brain rhythms and the emergence of structured brain activity. As well as the many insights that have been obtained from its mathematical analysis, it is now widely used in the computati...

journal_title：Journal of neurophysiology

authors： Byrne Á,O'Dea RD,Forrester M,Ross J,Coombes S

更新日期：2020-02-01 00:00:00

abstract：:Poststroke pain syndrome (PSPS) is an often intractable disorder characterized by hemiparesis associated with unrelenting chronic pain. Although traditional analgesics have largely failed, integrative approaches targeting affective-cognitive spheres have started to show promise. Recently, we demonstrated that deep bra...

journal_title：Journal of neurophysiology

authors： Gopalakrishnan R,Burgess RC,Malone DA,Lempka SF,Gale JT,Floden DP,Baker KB,Machado AG

更新日期：2018-06-01 00:00:00

abstract：:Rewards in the natural environment are rarely predicted with complete certainty. Uncertainty relating to future rewards has typically been defined as the variance of the potential outcomes. However, the asymmetry of predicted reward distributions, known as skewness, constitutes a distinct but neuroscientifically under...

journal_title：Journal of neurophysiology

authors： Burke CJ,Tobler PN

更新日期：2011-11-01 00:00:00

abstract：:Frequency facilitation is a process whereby neurosecretion increases as a function of stimulation frequency during repetitive synaptic activity. To examine the physiological basis underlying facilitation, we have estimated the frequency dependence of the synaptic parameters n (number of units capable of responding to ...

journal_title：Journal of neurophysiology

authors： Worden MK,Bykhovskaia M,Hackett JT

更新日期：1997-07-01 00:00:00

abstract：:1. Models of the saccadic system propose that there is an integration of the pulse signal, and there is good evidence that the integrator is reset gradually (Nichols and Sparks 1994, 1995). Other studies of the superior collicular contribution to the saccadic system have proposed a sensory, not motor, nature for its s...

journal_title：Journal of neurophysiology

authors： Kustov AA,Robinson DL

更新日期：1995-04-01 00:00:00

abstract：:Both N-methyl-D-aspartate (NMDA) and quisqualate/AMPA-insensitive metabotropic glutamate (mGlu) receptors mediate plasticity induction in neocortex, but their interlaminar distribution in cortical microcircuits is largely unknown. We used (+)(3)H-MK801 and (3)H-glutamate binding plus saturating concentrations of NMDA,...

journal_title：Journal of neurophysiology

authors： Hedberg TG,Sperber EF,Velísková J,Moshé SL

更新日期：2000-10-01 00:00:00

abstract：:Reports of cholecystokinin (CCK) binding and expression of CCK receptors in neonatal rodent spinal cord suggest that CCK may influence neuronal excitability. In patch-clamp recordings from 19/21 ventral horn motoneurons in neonatal (PN 5-12 days) rat spinal cord slices, we noted a slowly rising and prolonged membrane ...

journal_title：Journal of neurophysiology

authors： Oz M,Yang KH,Shippenberg TS,Renaud LP,O'Donovan MJ

更新日期：2007-09-01 00:00:00

abstract：:During priming of pop-out, performance at discriminating a pop-out feature target in visual search is affected by whether the target on the previous trial was defined by the same feature as on the upcoming trial. Recent studies suggest that priming of pop-out relies on attentional processes. With the use of simultaneo...

journal_title：Journal of neurophysiology

authors： Taylor PC,Muggleton NG,Kalla R,Walsh V,Eimer M

更新日期：2011-12-01 00:00:00

abstract：:We have investigated the fundamental properties of central auditory glycinergic synapses in early postnatal development in normal and congenitally deaf (dn/dn) mice. Glycinergic miniature inhibitory postsynaptic currents (mIPSCs) were recorded using patch-clamp methods in neurons from a brain slice preparation of the ...

journal_title：Journal of neurophysiology

authors： Leao RN,Oleskevich S,Sun H,Bautista M,Fyffe RE,Walmsley B

更新日期：2004-02-01 00:00:00

abstract：:Functional magnetic resonance imaging blood-oxygenation-level-dependent (BOLD) signal increases (activations) and BOLD signal decreases ("deactivations") were compared in six healthy volunteers during galvanic vestibular (mastoid) and galvanic cutaneous (neck) stimulation in order to differentiate vestibular from ocul...

journal_title：Journal of neurophysiology

authors： Bense S,Stephan T,Yousry TA,Brandt T,Dieterich M

更新日期：2001-02-01 00:00:00

abstract：:Twenty-four slowly adapting type 1 (SA1) and 26 rapidly adapting (RA) cutaneous mechanoreceptive afferents in the rhesus monkey were studied with an array of independently controlled, punctate probes that covered an entire fingerpad. Each afferent had a receptive field (RF) on a single fingerpad and was studied at 73 ...

journal_title：Journal of neurophysiology

authors： Vega-Bermudez F,Johnson KO

更新日期：1999-06-01 00:00:00

abstract：:The process of sensorimotor adaptation is considered to be driven by errors. While sensory prediction errors, defined as the difference between the planned and the actual movement of the cursor, drive implicit learning processes, target errors (e.g., the distance of the cursor from the target) are thought to drive exp...

journal_title：Journal of neurophysiology

authors： Reichenthal M,Avraham G,Karniel A,Shmuelof L

更新日期：2016-08-01 00:00:00

abstract：:The functional coupling of neural circuits between the upper and lower limbs involving rhythmic movements is of interest to both motor control research and rehabilitation science. This coupling can be detected by examining the effect of remote rhythmic limb movement on the modulation of reflex amplitude in stationary ...

journal_title：Journal of neurophysiology

authors： Sasada S,Tazoe T,Nakajima T,Zehr EP,Komiyama T

更新日期：2010-07-01 00:00:00

abstract：:1. Monkeys were trained to react to an arm perturbation according to an instruction delivered prior to the perturbation. There were two possible instructions (push or pull), and monkeys learned to respond accordingly regardless of the direction (push or pull) of the triggering perturbation. 2. Pyramidal tract neurons ...

journal_title：Journal of neurophysiology

authors： Evarts EV,Tanji J

更新日期：1976-09-01 00:00:00

abstract：:The objectives of this study were to probe the contribution of spinal neuron persistent sodium conductances to reflex hyperexcitability in human chronic spinal cord injury. The intrinsic excitability of spinal neurons provides a novel target for medical intervention. Studies in animal models have shown that persistent...

journal_title：Journal of neurophysiology

authors： Theiss RD,Hornby TG,Rymer WZ,Schmit BD

更新日期：2011-06-01 00:00:00

abstract：:Precisely synchronized neuronal activity has been commonly observed in the mammalian visual pathway. Spike timing correlations in the lateral geniculate nucleus (LGN) often take the form of phase synchronized oscillations in the high gamma frequency range. To study the relations between oscillatory activity, synchrony...

journal_title：Journal of neurophysiology

authors： Ito H,Maldonado PE,Gray CM

更新日期：2010-12-01 00:00:00