Transcorneal alternating current stimulation induces EEG "aftereffects" only in rats with an intact visual system but not after severe optic nerve damage.

abstract：:1. Recent immunocytochemical and receptor binding data have demonstrated a transient somatotopic patterning of serotonin (5-HT)-immunoreactive fibers in the primary somatosensory cortex of developing rats and a transient expression of 5-HT1B receptors on thalamocortical axons from the ventral posteromedial thalamic nu...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Bennett-Clarke CA,Shi MY,Mooney RD

更新日期：1994-11-01 00:00:00

abstract：:Spontaneous negative-going potentials occurring at an average frequency of 0.7 Hz were recorded from the dentate gyrus of slices prepared from the temporal hippocampus of young adult rats. These events (here termed "dentate waves") in several respects resembled the dentate spikes described for freely moving rats durin...

journal_title：Journal of neurophysiology

authors： Colgin LL,Kubota D,Brucher FA,Jia Y,Branyan E,Gall CM,Lynch G

更新日期：2004-12-01 00:00:00

abstract：:The lability of the responses of mammalian central neurons to gamma-aminobutyric acid (GABA) was studied using neurons acutely dissociated from the CA1 region of the adult guinea pig hippocampus as a model system. GABA was applied to the neuronal somata by pressure ejection and the resulting current (IGABA) recorded u...

journal_title：Journal of neurophysiology

authors： Huguenard JR,Alger BE

更新日期：1986-07-01 00:00:00

abstract：:1. Human flexor reflex (HFR) responses were elicited during ergometer cycling in neurologically intact humans with the objective of understanding the influence of lower limb muscle activity on phase-dependent reflex modulation during movement. The experimental setup permitted control over background muscle activity an...

journal_title：Journal of neurophysiology

authors： Brown DA,Kukulka CG

更新日期：1993-04-01 00:00:00

abstract：:Auditory nerve fibers are the major source of excitation to the three groups of principal cells of the ventral cochlear nucleus (VCN), bushy, T stellate, and octopus cells. Shock-evoked excitatory postsynaptic currents (eEPSCs) in slices from mice showed systematic differences between groups of principal cells, indica...

journal_title：Journal of neurophysiology

authors： Cao XJ,Oertel D

更新日期：2010-11-01 00:00:00

abstract：:AMPA-type glutamate receptors are normally Ca(2+) impermeable due to the expression of the GluR2 receptor subunit. By using GluR2 null mice we were able to detect miniature synaptic Ca(2+) transients (MSCTs) associated with AMPA-type receptor-mediated miniature synaptic currents at single synapses in primary cortical ...

journal_title：Journal of neurophysiology

authors： Wang S,Jia Z,Roder J,Murphy TH

更新日期：2002-07-01 00:00:00

abstract：:cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) are two major modulators of synaptic transmission in the CNS but little is known about how they affect synaptic transmission in the human CNS. In this study, we used forskolin, a PKA activator, and phorbol ester, a PKC activator, to examine the effects of ...

journal_title：Journal of neurophysiology

authors： Chen HX,Roper SN

更新日期：2003-05-01 00:00:00

abstract：:Increasing evidence demonstrates that modulating the cGMP-dependent protein kinase G (PKG) pathway produces an array of behavioral phenotypes in the fruit fly, Drosophila melanogaster. Altering PKG activity, either genetically via the foraging (for) gene or using pharmacology modifies tolerance to acute abiotic stress...

journal_title：Journal of neurophysiology

authors： Caplan SL,Milton SL,Dawson-Scully K

更新日期：2013-02-01 00:00:00

abstract：:We examined the activation kinetics of the delayed rectifier K+ current of bullfrog sympathetic neurons, primarily using whole cell recording. On depolarization, currents activated with a sigmoid delay but did not show a Cole-Moore shift. The time course of activation differed systematically from an exponential raised...

journal_title：Journal of neurophysiology

authors： Klemic KG,Durand DM,Jones SW

更新日期：1998-05-01 00:00:00

abstract：:The amino acid sequence of the N-methyl-D-aspartate (NMDA) receptor subunit NR2B from the brown ghost knife fish Apteronotus leptorhynchus has been determined and compared with the sequence of the murine NR2B. This comparison revealed high levels of sequence conservation throughout the ligand binding and membrane span...

journal_title：Journal of neurophysiology

authors： Harvey-Girard E,Dunn RJ

更新日期：2003-02-01 00:00:00

abstract：:It remains unclear how attention affects the tuning of individual neurons in visual cerebral cortex. Some observations suggest that attention preferentially enhances responses to low contrast stimuli, whereas others suggest that attention proportionally affects responses to all stimuli. Resolving how attention affects...

journal_title：Journal of neurophysiology

authors： Lee J,Maunsell JH

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to examine whether subjects who have learned a skilled locomotor task can transfer the acquired performance to conditions involving either a change in the external coordinates or in the sensory input from one leg. Subjects were trained to step over an obstacle with minimal foot clearance with...

journal_title：Journal of neurophysiology

authors： Lam T,Dietz V

更新日期：2004-10-01 00:00:00

abstract：:Secondary hyperalgesia is believed to be a key feature of "central sensitization" and is characterized by enhanced pain to mechanical nociceptive stimuli. The aim of the present study was to characterize, using EEG, the effects of pinprick stimulation intensity on the magnitude of pinprick-elicited brain potentials [e...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Mouraux A,Groneberg AH,Pfau DB,Treede RD,Klein T

更新日期：2015-11-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:Multimodal sensory integration facilitates the generation of a unified and coherent perception of the environment. It is now well established that unimodal sensory perceptions, such as vision, are improved in multisensory contexts. Whereas multimodal integration is primarily performed by dedicated multisensory brain r...

journal_title：Journal of neurophysiology

authors： McClure JP Jr,Polack PO

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this study was to compare the discharge characteristics of motor units recruited during an isometric contraction that was sustained with the elbow flexor muscles by older adults at target forces that were less than the recruitment threshold force of each isolated motor unit. The discharge times of 27 si...

journal_title：Journal of neurophysiology

authors： Pascoe MA,Holmes MR,Enoka RM

更新日期：2011-02-01 00:00:00

abstract：:Traditional electrophysiological research on invertebrate photoreceptors has been conducted in vivo, using intracellular recordings from intact compound eyes. The only exception used to be Drosophila melanogaster, which was exhaustively studied by both intracellular recording and patch-clamp methods. Recently, several...

journal_title：Journal of neurophysiology

authors： Frolov RV

更新日期：2016-08-01 00:00:00

abstract：:Targeting the melanin-concentrating hormone (MCH) system has been suggested as a potential treatment for obesity, anxiety disorders, as well as addiction. Despite the therapeutic potential of MCH agonists and antagonists, the endogenous factors regulating MCH activity, in particular those implicated in anxiety and rew...

journal_title：Journal of neurophysiology

authors： Parsons MP,Hirasawa M

更新日期：2011-03-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:We have found new evidence for gamma-aminobutyric acid (GABA)-induced intrinsic optical changes associated with a voltage-sensitive dye signal in the early embryonic chick brain stem slice. The slices were prepared from 8-day-old embryos, and they were stained with a voltage-sensitive dye (NK2761). Pressure ejection o...

journal_title：Journal of neurophysiology

authors： Momose-Sato Y,Sato K,Hirota A,Kamino K

更新日期：1998-04-01 00:00:00

abstract：:Since sensory systems operate with a finite quantity of processing resources, an animal would benefit from prioritizing processing of sensory stimuli within a time window that is expected to provide key information. This behavioral manifestation of such prioritization is known as attention. Here, we investigate attent...

journal_title：Journal of neurophysiology

authors： Lee CCY,Clifford CWG,Arabzadeh E

更新日期：2019-03-01 00:00:00

abstract：:1. In alert macaque monkeys, multiunit activity is encountered in an alternating sequence of silent and spontaneously active zones as an electrode is lowered through the striate cortex (V1). 2. Individual neurons that are spontaneously active in the dark usually have a maintained discharge in the light. Because both t...

journal_title：Journal of neurophysiology

authors： Snodderly DM,Gur M

更新日期：1995-11-01 00:00:00

abstract：:Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

journal_title：Journal of neurophysiology

authors： Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

更新日期：2019-05-01 00:00:00

abstract：:1. The role of sensory information in shaping muscle activation patterns to postural perturbations in humans was investigated by varying velocity, amplitude, or duration of the perturbing stimulus. Ten normal subjects were exposed to 120 backward translations of the support surface under conditions of varying velociti...

journal_title：Journal of neurophysiology

authors： Diener HC,Horak FB,Nashner LM

更新日期：1988-06-01 00:00:00

abstract：:Human languages can express opposite propositions by means of the negative operator "not," which turns affirmative sentences into negative ones. Psycholinguistic research has indicated that negative meanings are formed by transiently reducing the access to mental representations of negated conceptual information. Neur...

journal_title：Journal of neurophysiology

authors： Bartoli E,Tettamanti A,Farronato P,Caporizzo A,Moro A,Gatti R,Perani D,Tettamanti M

更新日期：2013-04-01 00:00:00

abstract：:1. The purpose of this study is to analyze the kinematics of stepping from the point of view of limb control by attempting to dissociate the various neuronal and mechanical factors that shape actual movements observed experimentally. The cat hindlimb, like the primate arm, is a multijointed mechanical system with redu...

journal_title：Journal of neurophysiology

authors： Shen L,Poppele RE

更新日期：1995-12-01 00:00:00

abstract：:Studies on animals have shown that noise-induced hearing loss is followed by an increase of spontaneous firing at several stages of the central auditory system. This central hyperactivity has been suggested to underpin the perception of tinnitus. It was shown that decreasing cochlear activity can abolish the noise-ind...

journal_title：Journal of neurophysiology

authors： Noreña AJ,Mulders WH,Robertson D

更新日期：2015-01-01 00:00:00

abstract：:In contrast to hand movements, the existence of a neural representation of saccade kinematics is unclear. Saccade kinematics is typically thought to be specified by motor error/desired displacement and generated by brain stem circuits that are not penetrable to voluntary control. We studied the influence of instructed...

journal_title：Journal of neurophysiology

authors： Gopal A,Jana S,Murthy A

更新日期：2017-09-01 00:00:00

abstract：:Evidence first described in reduced animal models over 100 years ago led to deductions about the control of locomotion through spinal locomotor central pattern-generating (CPG) networks. These discoveries in nature were contemporaneous with another form of deductive reasoning found in popular culture, that of Arthur C...

journal_title：Journal of neurophysiology

authors： Klarner T,Zehr EP

更新日期：2018-07-01 00:00:00