PKA and PKC enhance excitatory synaptic transmission in human dentate gyrus.

abstract：:The deep dorsal horn represents a major site for the integration of spinal sensory information. The bulbospinal monoamine transmitters, released from serotonergic, noradrenergic, and dopaminergic systems, exert modulatory control over spinal sensory systems as does acetylcholine, an intrinsic spinal cord biogenic amin...

journal_title：Journal of neurophysiology

authors： Garraway SM,Hochman S

更新日期：2001-11-01 00:00:00

abstract：:The input-output and discharge properties of neurons are shaped by both passive and active electrophysiological membrane properties. Whole cell patch-clamp recordings in lamina I-III neurons in an isolated preparation of the whole spinal cord of juvenile rats with attached dorsal roots and dorsal root ganglia were use...

journal_title：Journal of neurophysiology

authors： Dougherty PM,Chen J

更新日期：2016-09-01 00:00:00

abstract：:We studied the effects of horizontal smooth pursuit on the ocular responses to brief vertical perturbations of textured backgrounds in humans. When the subject was fixating on a stationary target, a brief vertical perturbation of the background elicited a small tracking response. When the subject was pursuing a target...

journal_title：Journal of neurophysiology

authors： Miura K,Kobayashi Y,Kawano K

更新日期：2009-09-01 00:00:00

abstract：:1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...

journal_title：Journal of neurophysiology

authors： Kang Y,Kayano F

更新日期：1994-08-01 00:00:00

abstract：:Spinal cord neuronal circuits generate motor neuron activity patterns responsible for rhythmic hindlimb behaviors such as scratching and swimming. Kinematic analyses of limb movements generated by this motor neuron output reveal important characteristics of these behaviors. Intralimb kinematics of the turtle hindlimb ...

journal_title：Journal of neurophysiology

authors： Field EC,Stein PS

更新日期：1997-09-01 00:00:00

abstract：:Previous analysis of the firing of individual rat hippocampal place cells has shown that their firing rate increases when they enter a place field and that their phase of firing relative to the ongoing theta oscillation (7-12 Hz) varies systematically as the rat traverses the place field, a phenomenon termed the theta...

journal_title：Journal of neurophysiology

authors： Jensen O,Lisman JE

更新日期：2000-05-01 00:00:00

abstract：:Older adults are at a high risk of falls, and most falls occur during locomotor activities like walking. This study aimed to improve our understanding of changes in neuromuscular control associated with increased risk of falls in older adults in the presence of dynamic balance challenges during walking. Motor module (...

journal_title：Journal of neurophysiology

authors： Allen JL,Franz JR

更新日期：2018-11-01 00:00:00

abstract：:The parafacial respiratory group (pFRG), located in the lateral aspect of the rostroventral lateral medulla, has been described as a conditional expiratory oscillator that emerges mainly in conditions of high metabolic challenges to increase breathing. The convergence of inhibitory and excitatory inputs to pFRG and th...

journal_title：Journal of neurophysiology

authors： Silva JDN,Oliveira LM,Souza FC,Moreira TS,Takakura AC

更新日期：2020-05-01 00:00:00

abstract：:The turtle posterior crista consists of two hemicristae. Each hemicrista extends from the planum semilunatum to the nonsensory torus and includes a central zone (CZ) surrounded by a peripheral zone (PZ). Type I and type II hair cells are found in the CZ and are innervated by calyx, dimorphic and bouton afferents. Only...

journal_title：Journal of neurophysiology

authors： Brichta AM,Goldberg JM

更新日期：2000-03-01 00:00:00

abstract：:Recent studies have shown that the initial responses evoked by a stimulus in neurons of primary visual cortex are dominated by low spatial frequency information in the image, whereas finer spatial scales dominate later in the response. Such phenomena could arise from the dynamics of receptive field (RF) size at early ...

journal_title：Journal of neurophysiology

authors： Malone BJ,Kumar VR,Ringach DL

更新日期：2007-01-01 00:00:00

abstract：:One-hertz repetitive transcranial magnetic stimulation (1Hz-rTMS) over ipsilateral motor cortex is able to modify up to 30 min the motor performance of repetitive finger opposition movements paced with a metronome at 2 Hz. We investigated whether the long-lasting rTMS effect on motor behavior can be modulated by subse...

journal_title：Journal of neurophysiology

authors： Avanzino L,Bove M,Tacchino A,Trompetto C,Ogliastro C,Abbruzzese G

更新日期：2009-03-01 00:00:00

abstract：:Behavioral and physiological characteristics of standing were studied in nontrained spinal cats and in spinal cats that received daily stand training of the hindlimbs for 12 wk. Training consisted of assisting the cats to stand with full weight support either on both hindlimbs or on one hindlimb (30 min/day, 5 days/wk...

journal_title：Journal of neurophysiology

authors： De Leon RD,Hodgson JA,Roy RR,Edgerton VR

更新日期：1998-07-01 00:00:00

abstract：:We investigated the precision of spike timing in a model of gap junction-coupled oscillatory neurons. The model incorporated the known physiology, morphology, and connectivity of the weakly electric fish's high-frequency and extremely precise pacemaker nucleus (Pn). Two neuron classes, pacemaker and relay cells, were ...

journal_title：Journal of neurophysiology

authors： Moortgat KT,Bullock TH,Sejnowski TJ

更新日期：2000-02-01 00:00:00

abstract：:Synchronization of local and distributed neuronal assemblies is thought to underlie fundamental brain processes such as perception, learning, and cognition. In neurological disease, neuronal synchrony can be altered and in epilepsy may play an important role in the generation of seizures. Linear cross-correlation and ...

journal_title：Journal of neurophysiology

authors： Warren CP,Hu S,Stead M,Brinkmann BH,Bower MR,Worrell GA

更新日期：2010-12-01 00:00:00

abstract：:1. Passive hyperpolarizing potentials (PHPs) have been recorded intracellularly from goldfish medullary neurons in the vicinity of the Mauthner cell (M-cell). They are evoked when this cell is activated antidromically by stimulation of the spinal cord, and orthodromically via the ipsilateral eighth nerve; when appropr...

journal_title：Journal of neurophysiology

authors： Korn H,Faber DS

更新日期：1975-03-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) controls mammalian reproduction via the hypothalamic-pituitary-gonadal (hpg) axis, acting on gonadotrope cells in the pituitary gland that express the GnRH receptor (GnRHR). Cells expressing the GnRHR have also been identified in the brain. However, the mechanism by which GnRH act...

journal_title：Journal of neurophysiology

authors： Schauer C,Tong T,Petitjean H,Blum T,Peron S,Mai O,Schmitz F,Boehm U,Leinders-Zufall T

更新日期：2015-08-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:1. The response properties of 39 periodontal ligament mechanoreceptors (PDLMs) and 12 intradental mechanoreceptors (IMs) related to the intact mandibular canine tooth were isolated by extracellular recording methods from the ipsilateral trigeminal semilunar ganglion. 2. The stimulus threshold and response magnitude of...

journal_title：Journal of neurophysiology

authors： Dong WK,Shiwaku T,Kawakami Y,Chudler EH

更新日期：1993-05-01 00:00:00

abstract：:When the head is free to move, electrical stimulation in the frontal eye field (FEF) evokes eye and head movements. However, it is unclear whether FEF stimulation-evoked head movements contribute to shifting the line of sight, like visually guided coordinated eye-head gaze shifts. Here we investigated this issue by sy...

journal_title：Journal of neurophysiology

authors： Chen LL

更新日期：2006-06-01 00:00:00

abstract：:We examined the contribution of the motor cortex to the control of intralimb coordination during reaching in the standing cat. We recorded the activity of 151 pyramidal tract neurons (PTNs) in the forelimb representation of three cats during a task in which the cat reached forward from a standing position to press a l...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Krouchev N,Drew T

更新日期：2011-01-01 00:00:00

abstract：:Systemic exposure to N-methyl-d-aspartate (NMDA) receptor antagonists can lead to psychosis and prefrontal cortex (PFC)-dependent behavioral impairments. Agonists of metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate the adverse behavioral effects of NMDA antagonists in humans and laboratory animals, and are be...

journal_title：Journal of neurophysiology

authors： Homayoun H,Jackson ME,Moghaddam B

更新日期：2005-04-01 00:00:00

abstract：:The nucleus of the tractus solitarius (NTS) plays an important role in the control of several autonomic reflex functions and has glutamate and GABA as main neurotransmitters. In this work, we used patch-clamp recordings in transverse slice preparations from rats to study whether the glycine binding site of the N-methy...

journal_title：Journal of neurophysiology

authors： Baptista V,Varanda WA

更新日期：2005-07-01 00:00:00

abstract：:Hippocampal mossy fiber axons simultaneously activate CA3 pyramidal cells and stratum lucidum interneurons (SLINs), the latter providing feedforward inhibition to control CA3 pyramidal cell excitability. Filopodial extensions of giant boutons of mossy fibers provide excitatory synaptic input to the SLIN. These filopod...

journal_title：Journal of neurophysiology

authors： Pan E,Zhao Z,McNamara JO

更新日期：2019-02-01 00:00:00

abstract：:In the first visual synapse of the insect compound eye, both the presynaptic and postsynaptic signals are graded, nonspiking changes in membrane voltage. The synapse exhibits tonic transmitter release (even in dark) and strong adaptation to long-lasting light backgrounds, leading to changes also in the dynamics of sig...

journal_title：Journal of neurophysiology

authors： Uusitalo RO,Weckström M

更新日期：2000-04-01 00:00:00

abstract：:Small lesions designed to completely destroy the cortical zone of representation of a restricted band of frequency were introduced within the primary auditory cortex (AI) in adult cats. Physiological mapping was used to guide placement of lesions. Sound-localization performance was evaluated prior to and after inducti...

journal_title：Journal of neurophysiology

authors： Jenkins WM,Merzenich MM

更新日期：1984-11-01 00:00:00

abstract：:The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...

journal_title：Journal of neurophysiology

authors： Nicholson DA,Freeman JH Jr

更新日期：2003-10-01 00:00:00

abstract：:In this study, we examined the effect of arachidonic acid (AA) on the BK alpha-subunit with or without beta-subunits expressed in Xenopus oocytes. In excised patches, AA potentiated the hSlo-alpha current and slowed inactivation only when beta2/3 subunit was co-expressed. The beta2-subunit-dependent modulation by AA p...

journal_title：Journal of neurophysiology

authors： Sun X,Zhou D,Zhang P,Moczydlowski EG,Haddad GG

更新日期：2007-01-01 00:00:00

abstract：:The essential role of calcium in the induction of long-term potentiation (LTP) has been well established. In particular, calcium influx via the N-methyl-D-aspartate (NMDA) receptor (NMDAR) is important for LTP induction in many pathways. However, the specific roles of other calcium sources in hippocampal LTP are less ...

journal_title：Journal of neurophysiology

authors： Raymond CR,Redman SJ

更新日期：2002-07-01 00:00:00

abstract：:1. Intracortical microstimulation (ICMS) techniques were used to derive detailed maps of distal forelimb movement representations in primary motor cortex (area 4) of adult squirrel monkeys before and a few months after a focal ischemic infarct. 2. Infarcts caused a marked but transient deficit in use of the contralate...

journal_title：Journal of neurophysiology

authors： Nudo RJ,Milliken GW

更新日期：1996-05-01 00:00:00

abstract：:Intracellular Ca2+ is influenced by both Ca2+ influx and release. We examined intracellular Ca2+ following action potential firing in the bag cell neurons of Aplysia californica. Following brief synaptic input, these neuroendocrine cells undergo an afterdischarge, resulting in elevated Ca2+ and the secretion of neurop...

journal_title：Journal of neurophysiology

authors： Geiger JE,Magoski NS

更新日期：2008-07-01 00:00:00