Potentiation in the first visual synapse of the fly compound eye.

Abstract:

:In the first visual synapse of the insect compound eye, both the presynaptic and postsynaptic signals are graded, nonspiking changes in membrane voltage. The synapse exhibits tonic transmitter release (even in dark) and strong adaptation to long-lasting light backgrounds, leading to changes also in the dynamics of signal transmission. We have studied these adaptational properties of the first visual synapse of the blowfly Calliphora vicina. Investigations were done in situ by intracellular recordings from the presynaptic photoreceptors, photoreceptor axon terminals, and the postsynaptic first order visual interneurons (LMCs). The dark recovery, the shifts in intensity dependence, and the underlying processes were studied by stimulating the visual system with various adapting stimuli while observing the recovery (i.e., dark adaptation). The findings show a transient potentiation in the postsynaptic responses after intense light adaptation, and the underlying mechanisms seem to be the changes in the equilibrium potential of the transmitter-gated conductance (chloride) of the postsynaptic neurons. The potentiation by itself serves as a mechanism that after light adaptation rapidly recovers the sensitivity loss of the visual system. However, this kind of mechanism, being an intrinsic property of graded potential transmission, may be quite widespread among graded synapses, and the phenomenon demonstrates that functional plasticity is also a property of graded synaptic transmission.

journal_name

J Neurophysiol

authors

Uusitalo RO,Weckström M

doi

10.1152/jn.2000.83.4.2103

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

2103-12

issue

4

eissn

0022-3077

issn

1522-1598

journal_volume

83

pub_type

杂志文章
  • Spatial bias in estimating the position of visual and proprioceptive targets.

    abstract::When people match an unseen hand to a visual or proprioceptive target, they make both variable and systematic (bias) errors. Variance is a well-established factor in behavior, but the origin and implications of bias, and its connection to variance, are poorly understood. Eighty healthy adults matched their unseen righ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00633.2017

    authors: Liu Y,Sexton BM,Block HJ

    更新日期:2018-05-01 00:00:00

  • Decomposition of surface EMG signals from cyclic dynamic contractions.

    abstract::Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00555.2014

    authors: De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

    更新日期:2015-03-15 00:00:00

  • Most superficial sublamina of rat superior colliculus: neuronal response properties and correlates with perceptual figure-ground segregation.

    abstract::The uppermost layer (stratum griseum superficiale, SGS) of the superior colliculus (SC) provides an important gateway from the retina to the visual extrastriate and visuomotor systems. The majority of attention has been given to the role of this "visual" SC in saccade generation and target selection and it is generall...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00059.2007

    authors: Girman SV,Lund RD

    更新日期:2007-07-01 00:00:00

  • Band-pass response properties of rat SI neurons.

    abstract::Rats typically employ 4- to 12-Hz "whisking" movements of their vibrissae during tactile exploration. The intentional sampling of signals in this frequency range suggests that neural processing of tactile information may be differentially engaged in this bandwidth. We examined action potential responses in rat primary...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01158.2002

    authors: Garabedian CE,Jones SR,Merzenich MM,Dale A,Moore CI

    更新日期:2003-09-01 00:00:00

  • Depolarization-induced facilitation of a plateau-generating current in ventral horn neurons in the turtle spinal cord.

    abstract::Plasticity at the neuronal level commonly involves use-dependent changes in strength of particular synaptic pathways or regulation of postsynaptic properties by modulatory transmitters. Here we analyze a novel form of short-term plasticity mediated by use-dependent facilitation of postsynaptic responsiveness. Using cu...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.3.1740

    authors: Svirskis G,Hounsgaard J

    更新日期:1997-09-01 00:00:00

  • Consolidation of visuomotor adaptation memory with consistent and noisy environments.

    abstract::Our understanding of how we learn and retain motor behaviors is still limited. For instance, there is conflicting evidence as to whether the memory of a learned visuomotor perturbation consolidates; i.e., the motor memory becomes resistant to interference from learning a competing perturbation over time. Here, we soug...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00178.2016

    authors: Maeda RS,McGee SE,Marigold DS

    更新日期:2017-01-01 00:00:00

  • Layer-specific modulation of entorhinal cortical excitability by presubiculum in a rat model of temporal lobe epilepsy.

    abstract::Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults and is often refractory to antiepileptic medications. The medial entorhinal area (MEA) is affected in TLE but mechanisms underlying hyperexcitability of MEA neurons require further elucidation. Previous studies suggest that inputs from the pres...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00823.2015

    authors: Abbasi S,Kumar SS

    更新日期:2015-11-01 00:00:00

  • Response adaptation in the barn owl's auditory space map.

    abstract::Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00769.2017

    authors: Ferger R,Pawlowsky K,Singheiser M,Wagner H

    更新日期:2018-03-01 00:00:00

  • Physiological effects of unequal alternating monocular exposure.

    abstract::1. In order to investigate the effects of an imbalance in stimulation to the eyes without the confounding influence of continuous deprivation of one eye, we reared cats with unequal alternating monocular exposure (AME) and, for comparison, cats with equal AME. We recorded extracellularly from single cells in area 17 o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1983.49.3.804

    authors: Tieman DG,McCall MA,Hirsch HV

    更新日期:1983-03-01 00:00:00

  • Wide dynamic range but not nociceptive-specific neurons encode multidimensional features of prolonged repetitive heat pain.

    abstract::1. To better characterize temporal and spatial mechanisms involved in the coding of prolonged nociceptive stimuli in the spinal cord, the responses of dorsal horn wide dynamic range (WDR) and nociceptive-specific (NS) neurons to prolonged, repetitive noxious heat stimuli (45-49 degrees C) were examined in unanesthetiz...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.3.703

    authors: Coghill RC,Mayer DJ,Price DD

    更新日期:1993-03-01 00:00:00

  • Muscle enzymatic changes induced by blockage of axoplasmic transport.

    abstract::The activity of malic dehydrogenase, pyruvic kinase, and phosphorylase b was measured in the geniohyoid muscle of the cat after injection of 10 10 mM colchicine into the hypoglossal nerve. Experiments performed 1-60 days after the injection showed that the activity of the three enzymes gradually decreased (day 4-5), r...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1976.39.6.1236

    authors: Inestrosa NC,Fernandez HL

    更新日期:1976-11-01 00:00:00

  • Functional properties and axon terminations of interneurons in laminae III-V of the mammalian spinal dorsal horn in vitro.

    abstract::1. The functional organization of interneurons in spinal laminae III-V was studied in an isolated preparation of hamster dorsal horn with sensory innervation from an excised skin patch. Morphological details of 40 neurons were visualized by intracellular injection of horseradish peroxidase. Active and passive membrane...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.5.1746

    authors: Schneider SP

    更新日期:1992-11-01 00:00:00

  • 5-HT modulation of hyperpolarization-activated inward current and calcium-dependent outward current in a crustacean motor neuron.

    abstract::1. Serotonergic modulation of a hyperpolarization-activated inward current, Ih, and a calcium-dependent outward current, Io(Ca), was examined in the dorsal gastric (DG) motor neuron, with the use of intracellular recording techniques in an isolated preparation of the crab stomatogastric ganglion (STG). 2. Hyperpolariz...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.2.496

    authors: Kiehn O,Harris-Warrick RM

    更新日期:1992-08-01 00:00:00

  • Limited interlimb transfer of locomotor adaptations to a velocity-dependent force field during unipedal walking.

    abstract::Several studies have demonstrated that motor adaptations to a novel task environment can be transferred between limbs. Such interlimb transfer of motor commands is consistent with the notion of centrally driven strategies that can be generalized across different frames of reference. So far, studies of interlimb transf...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00670.2011

    authors: Houldin A,Chua R,Carpenter MG,Lam T

    更新日期:2012-08-01 00:00:00

  • Microstimulation of the medullary reticular formation during fictive locomotion.

    abstract::1. The present study was designed to determine the effects of microstimulation of the medullary reticular formation (MRF) on the locomotor activity of the cat in the absence of phasic afferent feedback from the limbs. To this end, both short (33 ms) and long (200 ms) trains of stimuli (trains of 0.2-ms pulses at 330 H...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.71.1.229

    authors: Perreault MC,Rossignol S,Drew T

    更新日期:1994-01-01 00:00:00

  • Basolateral amygdala neurons are activated during threat expectation.

    abstract::Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00807.2018

    authors: Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

    更新日期:2019-05-01 00:00:00

  • Spatial structure of multiwhisker receptive fields in the barrel cortex is stimulus dependent.

    abstract::The tactile sensations mediated by the whisker-trigeminal system allow rodents to efficiently detect and discriminate objects. These capabilities rely strongly on the temporal and spatial structure of whisker deflections. Subthreshold but also spiking receptive fields in the barrel cortex encompass a large number of v...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00044.2011

    authors: Le Cam J,Estebanez L,Jacob V,Shulz DE

    更新日期:2011-08-01 00:00:00

  • Characteristics of a slow hyperpolarizing synaptic potential in rat hippocampal pyramidal cells in vitro.

    abstract::An orthodromically evoked late hyperpolarizing potential (LHP) was studied using intracellular recording techniques in rat hippocampal CA1 pyramidal cells in vitro. Several tests indicated that the LHP is not blocked by GABA antagonists, but rather comprises the initial portion of the stimulation-induced burst afterhy...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1984.52.5.892

    authors: Alger BE

    更新日期:1984-11-01 00:00:00

  • Rapid adaptation to scaled changes of the mechanical environment.

    abstract::We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00269.2007

    authors: Hinder MR,Milner TE

    更新日期:2007-11-01 00:00:00

  • Responses of neurons in the gracile nucleus of cats to innocuous and noxious stimuli: basic characterization and antidromic activation from the thalamus.

    abstract::1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.3.818

    authors: Cliffer KD,Hasegawa T,Willis WD

    更新日期:1992-09-01 00:00:00

  • Microstimulation of extrastriate area MST influences performance on a direction discrimination task.

    abstract::1. Evidence from single-unit recordings suggests that neurons in the medial superior temporal visual area (MST) carry directional signals that influence psychophysical judgements of motion direction. We tested this hypothesis by electrically stimulating clusters of directionally selective neurons in MST (the dorsomedi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.73.2.437

    authors: Celebrini S,Newsome WT

    更新日期:1995-02-01 00:00:00

  • Proximal arm kinematics affect grip force-load force coordination.

    abstract::During object manipulation, grip force is coordinated with load force, which is primarily determined by object kinematics. Proximal arm kinematics may affect grip force control, as proximal segment motion could affect control of distal hand muscles via biomechanical and/or neural pathways. The aim of this study was to...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00227.2015

    authors: Vermillion BC,Lum PS,Lee SW

    更新日期:2015-10-01 00:00:00

  • Direct recording of theta oscillations in primate prefrontal and anterior cingulate cortices.

    abstract::Recent evidence has suggested that theta-frequency (4-7 Hz) oscillations around the human anterior cingulate cortex (ACC) and frontal cortex--that is, frontal midline theta (Fm theta) oscillations--may be involved in attentional processes in the brain. However, little is known about the physiological basis of Fm theta...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00730.2005

    authors: Tsujimoto T,Shimazu H,Isomura Y

    更新日期:2006-05-01 00:00:00

  • Propagation of spindle waves in a thalamic slice model.

    abstract::1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.75.2.750

    authors: Golomb D,Wang XJ,Rinzel J

    更新日期:1996-02-01 00:00:00

  • Identification of the physical stimulus and the neural basis of fabric-evoked prickle.

    abstract::1. The neurophysiological basis for the sensation of prickle evoked by contact of some fabrics with the skin is reported. 2. Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle. These recordings showed that all low-threshold mec...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.4.1083

    authors: Garnsworthy RK,Gully RL,Kenins P,Mayfield RJ,Westerman RA

    更新日期:1988-04-01 00:00:00

  • Functional alterations of cat abducens neurons after peripheral tetanus neurotoxin injection.

    abstract::Tetanus neurotoxin (TeNT) cleaves synaptobrevin, a protein involved in synaptic vesicle docking and fusion, thereby preventing neurotransmitter release and causing a functional deafferentation. We injected TeNT into the lateral rectus muscle of adult cats at 0.5 or 5 ng/kg (low and high dose, respectively). In the per...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01006.2002

    authors: Gonzalez-Forero D,de la Cruz RR,Delgado-Garcia JM,Alvarez FJ,Pastor AM

    更新日期:2003-04-01 00:00:00

  • Rectification of EMG in low force contractions improves detection of motor unit coherence in the beta-frequency band.

    abstract::Rectification of surface EMG before spectral analysis is a well-established preprocessing method used in the detection of motor unit firing patterns. A number of recent studies have called into question the need for rectification before spectral analysis, pointing out that there is no supporting experimental evidence ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00296.2013

    authors: Ward NJ,Farmer SF,Berthouze L,Halliday DM

    更新日期:2013-10-01 00:00:00

  • Muscle spindles in human tibialis anterior encode muscle fascicle length changes.

    abstract::Muscle spindles provide exquisitely sensitive proprioceptive information regarding joint position and movement. Through passively driven length changes in the muscle-tendon unit (MTU), muscle spindles detect joint rotations because of their in-parallel mechanical linkage to muscle fascicles. In human microneurography ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00374.2016

    authors: Day J,Bent LR,Birznieks I,Macefield VG,Cresswell AG

    更新日期:2017-04-01 00:00:00

  • Triple dissociation in the medial temporal lobes: recollection, familiarity, and novelty.

    abstract::Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence of contextual details. There are indications that recollection, familiarity, and novelty involve different medial temporal lobe ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01029.2005

    authors: Daselaar SM,Fleck MS,Cabeza R

    更新日期:2006-10-01 00:00:00

  • Mechanosensitive properties of gastric vagal afferent fibers in the rat.

    abstract::Single, teased fiber recordings were made from the decentralized right cervical vagus nerve (hyponodal) of the rat. A total of 67 afferent fibers that responded to gastric distension (GD) were studied: 9 fibers were stimulated by phasic balloon GD, 58 by more natural fluid GD. All balloon GD-responsive fibers had rest...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.5.2210

    authors: Ozaki N,Sengupta JN,Gebhart GF

    更新日期:1999-11-01 00:00:00