Excitatory amino acid receptors of the electrosensory system: the NR1/NR2B N-methyl-D-aspartate receptor.

abstract：:Responses to rapid application of glutamic acid (Glu) and gamma-aminobutyric acid (GABA), 0.01-3 mM, were recorded by whole-cell patch clamp of cultured crab (Cardisoma carnifex) X-organ neurons. Responses peaked within 200 ms. Both Glu and GABA currents had reversal potentials that followed the Nernst Cl(-) potential...

journal_title：Journal of neurophysiology

authors： Duan S,Cooke IM

更新日期：2000-01-01 00:00:00

abstract：:1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

journal_title：Journal of neurophysiology

authors： Chamberlain SC,Barlow RB Jr

更新日期：1982-08-01 00:00:00

abstract：:Adaptation of movement may be driven by the difference between planned and actual motor performance, or the difference between expected and actual sensory consequences of movement. To identify how the nervous system differentially uses these signals, we asked: does motor adaptation occur when movement errors are irrel...

journal_title：Journal of neurophysiology

authors： Schaefer SY,Shelly IL,Thoroughman KA

更新日期：2012-02-01 00:00:00

abstract：:Paired-pulse transcranial magnetic stimulation (TMS) and peripheral stimulation combined with TMS can be used to study cortical interneuronal circuitry. By combining these procedures with concurrent transcranial alternating current stimulation (tACS), Guerra and colleagues recently showed that different cortical inter...

journal_title：Journal of neurophysiology

authors： Hussain SJ,Thirugnanasambandam N

更新日期：2017-06-01 00:00:00

abstract：:Purinoreceptors of the P2 family contribute strongly to signaling in the cochlea, but little is known about the effects of purinergic neurotransmission in the central auditory system. Here we examine P2 receptor-mediated signaling in the large spherical bushy cells (SBCs) of Mongolian gerbils around the onset of acous...

journal_title：Journal of neurophysiology

authors： Milenkovic I,Rinke I,Witte M,Dietz B,Rübsamen R

更新日期：2009-09-01 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:Hippocampal neurons show a strong modulation by theta frequency oscillations. This modulation is thought to be important not only for temporal encoding and decoding of information in the hippocampal system, but also for temporal ordering of neuronal activities on timescales at which physiological mechanisms of synapti...

journal_title：Journal of neurophysiology

authors： Deshmukh SS,Yoganarasimha D,Voicu H,Knierim JJ

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to examine the effects of kappa-opioid receptor selective agonists on responses of mechanosensitive afferent fibers in the pelvic nerve. Single-fiber recordings were made from pelvic nerve afferents in the decentralized S1 dorsal root of the rat. A total of 572 afferent fibers in the S1 dorsa...

journal_title：Journal of neurophysiology

authors： Su X,Sengupta JN,Gebhart GF

更新日期：1997-08-01 00:00:00

abstract：:The purpose of the present study was to determine whether retinal activity can support long-term changes in synaptic strength in the developing dorsal lateral geniculate nucleus (LGN) of thalamus. To test for this we made use of a rodent in vitro explant preparation in which retinal afferents and the intrinsic circuit...

journal_title：Journal of neurophysiology

authors： Ziburkus J,Dilger EK,Lo FS,Guido W

更新日期：2009-12-01 00:00:00

abstract：:Astrocyte-derived lactate supports pathologically enhanced neuronal metabolism, but its role under physiological conditions is still a matter of debate. Here, we determined the contribution of astrocytic neuronal lactate shuttle for maintenance of ion homeostasis and energy metabolism. We tested for the effects of α-c...

journal_title：Journal of neurophysiology

authors： Angamo EA,Rösner J,Liotta A,Kovács R,Heinemann U

更新日期：2016-11-01 00:00:00

abstract：:The ventroposterior region of the thalamus of mongrel cats was searched to locate zones activated by somatic stimuli. By using stimuli that selectively excited Pacinian corpuscles, areas activated by this class of afferent fibers were differentiated from regions activated by other classes of cutaneous mechanoreceptors...

journal_title：Journal of neurophysiology

authors： Herron P,Dykes R

更新日期：1986-12-01 00:00:00

abstract：:Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, is caused by loss of the fragile X mental retardation protein (FMRP). FMRP is a negative regulator of local mRNA translation downstream of group 1 metabotropic glutamate receptor (Gp1 mGluR) activation. In the absence of FMRP there is...

journal_title：Journal of neurophysiology

authors： Auerbach BD,Bear MF

更新日期：2010-08-01 00:00:00

abstract：:We investigated the role of the superior colliculus (SC) in saccade target selection in rhesus monkeys who were trained to perform a direction-discrimination task. In this task, the monkey discriminated between opposed directions of visual motion and indicated its judgment by making a saccadic eye movement to one of t...

journal_title：Journal of neurophysiology

authors： Horwitz GD,Newsome WT

更新日期：2001-11-01 00:00:00

abstract：:The possibility of using randomly generated stimulus intervals (with a Poisson distribution) to identify the type(s) of intrafusal fiber activated by the stimulation of single static gamma axons was tested in Peroneus tertius muscle spindles of anesthetized cats. Three patterns of random stimulation with different val...

journal_title：Journal of neurophysiology

authors： Petit J,Banks RW,Laporte Y

更新日期：1999-06-01 00:00:00

abstract：:The way in which input noise perturbs the behavior of a system depends on the internal processing structure of the system. In visual psychophysics, there is a long tradition of using external noise methods (i.e., adding noise to visual stimuli) as tools for system identification. Here, we demonstrate that external noi...

journal_title：Journal of neurophysiology

authors： Tjan BS,Lestou V,Kourtzi Z

更新日期：2006-09-01 00:00:00

abstract：:Motor imagery (MI) is a promising rehabilitation technique that has received significant interest for use in persons with multiple sclerosis (MS). Through alterations in neural networks, MI has the potential to improve measures of walking speed, walking distance, and fatigue in people with MS. Further research is requ...

journal_title：Journal of neurophysiology

authors： Hanson M,Concialdi M

更新日期：2019-02-01 00:00:00

abstract：:The performance of neural codes to represent attributes of sensory signals has been evaluated in the vertebrate peripheral and central nervous system. Here, we determine how information signaled by populations of neurons is modified by plasticity. Suprathreshold neuronal responses from a large number of neurons were r...

journal_title：Journal of neurophysiology

authors： Pita-Almenar JD,Ranganathan GN,Koester HJ

更新日期：2011-09-01 00:00:00

abstract：:Macaque SEF neurons encode object-centered directions of eye movements regardless of the visual attributes of instructional cues. Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit object-centered direction selectivity in the context of a task in which a spot flashed on the right or left end of...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN

更新日期：1999-05-01 00:00:00

abstract：:1. Monkeys with large unilateral surgical ablations of striate cortex, sustained either in adulthood or at 5-6 wk of age, were trained on an oculomotor detection and localization task and tested with visual stimuli in the hemifields ipsilateral and contralateral to the lesion 2-5 yr after surgery. 2. Monkeys with lesi...

journal_title：Journal of neurophysiology

authors： Moore T,Rodman HR,Repp AB,Gross CG,Mezrich RS

更新日期：1996-12-01 00:00:00

abstract：:Precisely synchronized neuronal activity has been commonly observed in the mammalian visual pathway. Spike timing correlations in the lateral geniculate nucleus (LGN) often take the form of phase synchronized oscillations in the high gamma frequency range. To study the relations between oscillatory activity, synchrony...

journal_title：Journal of neurophysiology

authors： Ito H,Maldonado PE,Gray CM

更新日期：2010-12-01 00:00:00

abstract：:1. Axonal transection triggers a cascade of pathological processes that frequently lead to the degeneration of the injured neuron. It is generally believed that the degenerative process is triggered by an overwhelming influx of calcium through the cut end of the axon. 2. Theoretical considerations and indirect observa...

journal_title：Journal of neurophysiology

authors： Ziv NE,Spira ME

更新日期：1995-12-01 00:00:00

abstract：:Several qualitative features distinguish bipedal from quadrupedal locomotion in mammals. In this study we show quantitative differences between quadrupedal and bipedal gait in the Japanese monkey in terms of gait patterns, trunk/hindlimb kinematics, and electromyographic (EMG) activity, obtained from 3 macaques during...

journal_title：Journal of neurophysiology

authors： Higurashi Y,Maier MA,Nakajima K,Morita K,Fujiki S,Aoi S,Mori F,Murata A,Inase M

更新日期：2019-07-01 00:00:00

abstract：:1. We studied adenosine's action on synaptic transmission from primary afferent fibers to neurons of the substantia gelatinosa (SG) using tight-seal whole cell recordings in transverse slices of hamster spinal cord. Adenosine had two actions, hyperpolarization of the postsynaptic membrane and depression of the excitat...

journal_title：Journal of neurophysiology

authors： Li J,Perl ER

更新日期：1994-10-01 00:00:00

abstract：:1. Spontaneous synaptic activity in networks formed by dissociated neurons from embryonic rat midbrain was analyzed in tight seal whole cell recordings. 2. Application of furosemide (0.5 mM) to the cell and its surrounding area increased the frequency of spontaneous synaptic currents. Incubation of the culture with fu...

journal_title：Journal of neurophysiology

authors： Jarolimek W,Brunner H,Lewen A,Misgeld U

更新日期：1996-06-01 00:00:00

abstract：:The hypocretin/orexins (Hcrt/Orxs) are hypothalamic neuropeptides that regulate stress, addiction, feeding, and arousal behaviors. They depolarize many types of central neurons and can increase [Ca2+]i in some, including those of the dorsal raphe (DR) and laterodorsal tegmental (LDT) nuclei-two structures likely to co...

journal_title：Journal of neurophysiology

authors： Kohlmeier KA,Watanabe S,Tyler CJ,Burlet S,Leonard CS

更新日期：2008-10-01 00:00:00

abstract：:Regularly discharging vestibular-nerve afferents innervating the semicircular canals were recorded extracellularly in anesthetized chinchillas undergoing high-frequency, high-velocity sinusoidal rotations. In the range from 2 to 20 Hz, with peak velocities of 151 degrees/s at 6 Hz and 52 degrees/s at 20 Hz, 67/70 (96%...

journal_title：Journal of neurophysiology

authors： Hullar TE,Minor LB

更新日期：1999-10-01 00:00:00

abstract：:1. Whole cell patch-clamp experiments were conducted to determine whether rat aortic baroreceptor neurons contain mechano-sensitive conductances. 2. Putative aortic baroreceptor neurons in the nodose ganglia were identified by injecting DiI onto the adventitia of the aortic arch. Nodose ganglia neurons were dissociate...

journal_title：Journal of neurophysiology

authors： Cunningham JT,Wachtel RE,Abboud FM

更新日期：1995-05-01 00:00:00

abstract：:1. Responses to pure tones were recorded from single neurons in the anteroventral cochlear nucleus (AVCN) in kittens ranging in age from 4 to 45 days. Different response properties mature at different times after birth. 2. The shapes of response areas of AVCN neurons after the 1st postnatal week resemble those recorde...

journal_title：Journal of neurophysiology

authors： Brugge JF,Javel E,Kitzes LM

更新日期：1978-11-01 00:00:00

abstract：:The functional role of input from the primary motor cortex (M1) to primary somatosensory cortex (S1) is unclear; one key to understanding this pathway may lie in elucidating the cell-type specific microcircuits that connect S1 and M1. Recently, we discovered that a subset of pyramidal neurons in the infragranular laye...

journal_title：Journal of neurophysiology

authors： Kinnischtzke AK,Fanselow EE,Simons DJ

更新日期：2016-09-01 00:00:00

abstract：:Extracellular calcium is critical for many neural functions, including neurotransmission, cell adhesion, and neural plasticity. Experiments have shown that normal neural activity is associated with changes in extracellular calcium, which has motivated recent computational work that employs such fluctuations in an info...

journal_title：Journal of neurophysiology

authors： Wiest MC,Eagleman DM,King RD,Montague PR

更新日期：2000-03-01 00:00:00