GIRK channel-mediated inhibition of melanin-concentrating hormone neurons by nociceptin/orphanin FQ.

abstract：:The inhibitory circuits of the striatum are known to be critical for motor function, yet their contributions to Parkinsonian motor deficits are not clear. Altered firing in the globus pallidus suggests that striatal medium spiny neurons (MSN) of the direct (D1 MSN) and indirect pathway (D2 MSN) are imbalanced during d...

journal_title：Journal of neurophysiology

authors： Damodaran S,Evans RC,Blackwell KT

更新日期：2014-02-01 00:00:00

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:Small lesions designed to completely destroy the cortical zone of representation of a restricted band of frequency were introduced within the primary auditory cortex (AI) in adult cats. Physiological mapping was used to guide placement of lesions. Sound-localization performance was evaluated prior to and after inducti...

journal_title：Journal of neurophysiology

authors： Jenkins WM,Merzenich MM

更新日期：1984-11-01 00:00:00

abstract：:1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young rabbit hippocampal CA1 pyramidal cells in vitro. Various concentrations of nimodipine, ranging from 10 nM to 10 microM, were tested to investigate age- and concen...

journal_title：Journal of neurophysiology

authors： Moyer JR Jr,Thompson LT,Black JP,Disterhoft JF

更新日期：1992-12-01 00:00:00

abstract：:GABA(B)-receptor-mediated inhibition was investigated in anatomically identified inhibitory interneurons located at the border between the dentate gyrus granule cell layer and hilus. Biocytin staining was used to visualize the morphology of recorded cells. A molecular layer stimulus evoked a pharmacologically isolated...

journal_title：Journal of neurophysiology

authors： Mott DD,Li Q,Okazaki MM,Turner DA,Lewis DV

更新日期：1999-09-01 00:00:00

abstract：:In this report, we provide the first characterization of abducens nucleus neuron (ABN) discharge dynamics during horizontal disjunctive saccades. These movements function to rapidly transfer the visual axes between targets located at different eccentricities and depths. Our primary objective was to determine whether t...

journal_title：Journal of neurophysiology

authors： Sylvestre PA,Cullen KE

更新日期：2002-12-01 00:00:00

abstract：:As a vital skill in an evolving world, interception of moving objects relies on accurate prediction of target motion. In natural circumstances, active gaze shifts often accompany hand movements when exploring targets of interest, but how eye and hand movements are coordinated during manual interception and their depen...

journal_title：Journal of neurophysiology

authors： Li Y,Wang Y,Cui H

更新日期：2018-01-01 00:00:00

abstract：:The cerebellum has long been recognized to play an important role in motor adaptation. Individuals with cerebellar ataxia exhibit impaired learning in visuomotor adaptation tasks such as prism adaptation and force field learning. Both types of tasks involve the adjustment of an internal model to compensate for an exte...

journal_title：Journal of neurophysiology

authors： Schlerf JE,Xu J,Klemfuss NM,Griffiths TL,Ivry RB

更新日期：2013-02-01 00:00:00

abstract：:The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the exclusive relay of retinal information en route to the visual cortex. Although much of our understanding about dLGN comes from studies done in higher mammals, such as the cat and primate, the mouse as a model organism has moved to the forefront as a t...

journal_title：Journal of neurophysiology

authors： Guido W

更新日期：2018-07-01 00:00:00

abstract：:Recording simultaneous activity of a large number of neurons in distributed neuronal networks is crucial to understand higher order brain functions. We demonstrate the in vivo performance of a recently developed electrophysiological recording system comprising a two-dimensional, multi-shank, high-density silicon probe...

journal_title：Journal of neurophysiology

authors： Fiáth R,Beregszászi P,Horváth D,Wittner L,Aarts AA,Ruther P,Neves HP,Bokor H,Acsády L,Ulbert I

更新日期：2016-11-01 00:00:00

abstract：:We cloned 10 full-length variants of PIIH, the gene for I(h) from the spiny lobster, Panulirus interruptus, using reverse transcription-PCR (RT-PCR) and rapid amplification of cDNA ends (RACE). This gene shows a significant amount of alternative splicing in the S3-S4 and S4-S5 linkers, in the P-loop and the entire S6 ...

journal_title：Journal of neurophysiology

authors： Ouyang Q,Goeritz M,Harris-Warrick RM

更新日期：2007-06-01 00:00:00

abstract：:We examined the contribution of the motor cortex to the control of intralimb coordination during reaching in the standing cat. We recorded the activity of 151 pyramidal tract neurons (PTNs) in the forelimb representation of three cats during a task in which the cat reached forward from a standing position to press a l...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Krouchev N,Drew T

更新日期：2011-01-01 00:00:00

abstract：:1. Eleven adult cats were trained to stop inspiration in response to a conditioning stimulus. The conditioning stimuli were presented at the onset of inspiration at intervals of approximately 20-30 s. Intratracheal pressures, diaphragmatic activity, and the extracellular activity of single medullary respiratory neuron...

journal_title：Journal of neurophysiology

authors： Orem J

更新日期：1989-11-01 00:00:00

abstract：:1. Two subtypes of astrocytes that expressed distinctly different ion channel complements were identified in primary cultures from rat spinal cord and hippocampus using whole cell patch-clamp techniques. One population of cells expressed voltage-activated Na+ currents and displayed outwardly rectifying I-V relationshi...

journal_title：Journal of neurophysiology

authors： Ransom CB,Sontheimer H,Janigro D

更新日期：1996-07-01 00:00:00

abstract：:Much has been studied and written about plastic changes in the CNS of humans triggered by events such as limb amputation. However, little is known about the extent to which the original pathways retain residual function after peripheral amputation. Our earlier, acute study on long-term amputees indicated that central ...

journal_title：Journal of neurophysiology

authors： Dhillon GS,Krüger TB,Sandhu JS,Horch KW

更新日期：2005-05-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the ...

journal_title：Journal of neurophysiology

authors： Heim M,Rousseau L,Reculusa S,Urbanova V,Mazzocco C,Joucla S,Bouffier L,Vytras K,Bartlett P,Kuhn A,Yvert B

更新日期：2012-09-01 00:00:00

abstract：:1. Whether complex (C) cells are the only truly texture-sensitive units in the cat's primary visual cortex remains controversial. In view of the strong physiological significance of having putatively only one class of cells sensitive to visual noise in the striate cortex, we reinvestigated this issue. Sensitivities of...

journal_title：Journal of neurophysiology

authors： Casanova C,Savard T,Nordmann JP,Molotchnikoff S,Minville K

更新日期：1995-09-01 00:00:00

abstract：:Both N-methyl-D-aspartate (NMDA) and quisqualate/AMPA-insensitive metabotropic glutamate (mGlu) receptors mediate plasticity induction in neocortex, but their interlaminar distribution in cortical microcircuits is largely unknown. We used (+)(3)H-MK801 and (3)H-glutamate binding plus saturating concentrations of NMDA,...

journal_title：Journal of neurophysiology

authors： Hedberg TG,Sperber EF,Velísková J,Moshé SL

更新日期：2000-10-01 00:00:00

abstract：:In songbirds, the basal ganglia outflow nucleus LMAN is a cortical analog that is required for several forms of song plasticity and learning. Moreover, in adults, inactivating LMAN can reverse the initial expression of learning driven via aversive reinforcement. In the present study, we investigated how LMAN contribut...

journal_title：Journal of neurophysiology

authors： Warren TL,Tumer EC,Charlesworth JD,Brainard MS

更新日期：2011-10-01 00:00:00

abstract：:Recent physiological studies have suggested that there are several sites of interaction between the neural pathways that control saccadic eye movements and those that control visual pursuit movements. To address the question of saccade/pursuit interaction from a neuroanatomical point of view, we have studied the conne...

journal_title：Journal of neurophysiology

authors： Yan YJ,Cui DM,Lynch JC

更新日期：2001-12-01 00:00:00

abstract：:Sensory areas should be adapted to the properties of their natural stimuli. What are the underlying rules that match the properties of complex cells in primary visual cortex to their natural stimuli? To address this issue, we sampled movies from a camera carried by a freely moving cat, capturing the dynamics of image ...

journal_title：Journal of neurophysiology

authors： Körding KP,Kayser C,Einhäuser W,König P

更新日期：2004-01-01 00:00:00

abstract：:Endocannabinoids are lipid derivatives that mediate paracrine and juxtacrine signaling between cells. In the hippocampal CA1 region, a retrograde endocannabinoid signal suppresses GABA release by acting on presynaptic cannabinoid receptor-1 (CB1) and can be functionally manifested as depolarization-induced suppression...

journal_title：Journal of neurophysiology

authors： Zhu PJ,Lovinger DM

更新日期：2010-02-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:1. Study of memory traces in higher animals requires experimental models possessing well-localized and technically accessible memory traces--plasticity responsible for behavioral change, not dependent on control from elsewhere, and open to detailed investigation. Our purpose has been to develop such a model based on t...

journal_title：Journal of neurophysiology

authors： Wolpaw JR,Lee CL

更新日期：1989-03-01 00:00:00

abstract：:1. Properties of 90 lateral cervical nucleus (LCN) neurons responsive to light tactile stimulation of ipsilateral body surfaces were examined in pentobarbital sodium-anesthetized raccoons. Peripheral receptive fields (RFs) of 60 of these lay totally or partially on glabrous skin of the forepaw. There were 71 neurons a...

journal_title：Journal of neurophysiology

authors： Simone DA,Pubols BH Jr

更新日期：1991-06-01 00:00:00

abstract：:Traditional electrophysiological research on invertebrate photoreceptors has been conducted in vivo, using intracellular recordings from intact compound eyes. The only exception used to be Drosophila melanogaster, which was exhaustively studied by both intracellular recording and patch-clamp methods. Recently, several...

journal_title：Journal of neurophysiology

authors： Frolov RV

更新日期：2016-08-01 00:00:00

abstract：:Frequency facilitation is a process whereby neurosecretion increases as a function of stimulation frequency during repetitive synaptic activity. To examine the physiological basis underlying facilitation, we have estimated the frequency dependence of the synaptic parameters n (number of units capable of responding to ...

journal_title：Journal of neurophysiology

authors： Worden MK,Bykhovskaia M,Hackett JT

更新日期：1997-07-01 00:00:00

abstract：:Ankle inversions have been studied extensively during standing conditions. However, inversion traumas occur during more dynamic conditions, like walking. Therefore in this study sudden ankle inversions were elicited in 12 healthy subjects who stepped on a trap door while walking on a treadmill. First, 10 control trial...

journal_title：Journal of neurophysiology

authors： Nieuwenhuijzen PH,Duysens J

更新日期：2007-10-01 00:00:00

abstract：:We investigated the afferents and intracortical synaptic organization of the anterior cingulate cortex (ACC) during noxious electrical stimulation. Extracellular field potentials were recorded simultaneously from 16 electrodes spanning all layers of the ACC in male Sprague-Dawley rats anesthetized by halothane inhalat...

journal_title：Journal of neurophysiology

authors： Yang JW,Shih HC,Shyu BC

更新日期：2006-12-01 00:00:00