Combined macro-/mesoporous microelectrode arrays for low-noise extracellular recording of neural networks.

abstract：:How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed...

journal_title：Journal of neurophysiology

authors： Hammerbeck U,Yousif N,Greenwood R,Rothwell JC,Diedrichsen J

更新日期：2014-01-01 00:00:00

abstract：:Despite the peripheral and central immaturities that limit auditory processing in juvenile animals, they are able to lateralize sounds using binaural cues. This study explores a central mechanism that may compensate for these limitations during development. Interaural time and level difference processing by neurons in...

journal_title：Journal of neurophysiology

authors： Green JS,Sanes DH

更新日期：2005-12-01 00:00:00

abstract：:Metabotropic receptors modulate numerous cellular processes by intracellular Ca2+ signaling, but less is known about their role in regulating mitochondrial metabolic function within the CNS. In this study, we demonstrate in area CA3 of rat organotypic hippocampal slice cultures that glutamatergic, serotonergic, and mu...

journal_title：Journal of neurophysiology

authors： Kann O,Kovács R,Heinemann U

更新日期：2003-08-01 00:00:00

abstract：:With each eye movement, stationary objects in the world change position on the retina, yet we perceive the world as stable. Spatial updating, or remapping, is one neural mechanism by which the brain compensates for shifts in the retinal image caused by voluntary eye movements. Remapping of a visual representation is b...

journal_title：Journal of neurophysiology

authors： Merriam EP,Genovese CR,Colby CL

更新日期：2007-02-01 00:00:00

abstract：:The complementary DNA encoding gustatory cyclic nucleotide--gated ion channel (or gustCNG channel) cloned from rat tongue epithelial tissue was expressed in Xenopus oocytes, and its electrophysiological characteristics were investigated using tight-seal patch-clamp recordings of single and macroscopic channel currents...

journal_title：Journal of neurophysiology

authors： Lee HM,Park YS,Kim W,Park CS

更新日期：2001-06-01 00:00:00

abstract：:Adult neuronal phenotype is maintained, at least in part, by the sensitivity of individual neurons to a specific selection of neurotrophic factors and the availability of such factors in the neurons' environment. Nerve growth factor (NGF) increases the functional expression of Na(+) channel currents (I(Na)) and both N...

journal_title：Journal of neurophysiology

authors： Ford CP,Wong KV,Lu VB,Posse de Chaves E,Smith PA

更新日期：2008-03-01 00:00:00

abstract：:We examined the contribution of the motor cortex to the control of intralimb coordination during reaching in the standing cat. We recorded the activity of 151 pyramidal tract neurons (PTNs) in the forelimb representation of three cats during a task in which the cat reached forward from a standing position to press a l...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Krouchev N,Drew T

更新日期：2011-01-01 00:00:00

abstract：:1. The rostromesial agranular frontal cortex of macaque monkey (Macaca fuscata), traditionally defined as the supplementary motor area (SMA), was studied using various physiological techniques to delineate two different areas rostrocaudally. 2. Field and unitary responses to electrical stimulation of the primary motor...

journal_title：Journal of neurophysiology

authors： Matsuzaka Y,Aizawa H,Tanji J

更新日期：1992-09-01 00:00:00

abstract：:The functional significance of vestibular information for the generation of gaze shifts is controversial and less well established than the vestibular contribution to gaze stability. In this study, we asked seven bilaterally avestibular patients to execute voluntary, whole body pivot turns to visual targets up to 180°...

journal_title：Journal of neurophysiology

authors： Anastasopoulos D,Ziavra N,Bronstein AM

更新日期：2019-11-01 00:00:00

abstract：:The central auditory system has traditionally been divided into lemniscal and nonlemniscal pathways leading from the midbrain through the thalamus to the cortex. This view has served as an organizing principle for studying, modeling, and understanding the encoding of sound within the brain. However, there is evidence ...

journal_title：Journal of neurophysiology

authors： Straka MM,Schmitz S,Lim HH

更新日期：2014-08-15 00:00:00

abstract：:1. To analyze further the sensory mechanisms for triggering the lordosis reflex, single-unit (n = 345) activity was recorded extracellularly from spinal segments L5-S1 of urethan-anesthetized female rats. Unit responses to pressure on the skin (necessary and sufficient for evoking lordosis) and other mechanical stimul...

journal_title：Journal of neurophysiology

authors： Kow LM,Zemlan FP,Pfaff DW

更新日期：1980-01-01 00:00:00

abstract：:The centre médian-parafascicular (CM-Pf) complex is located at the posterior intralaminar nuclei of the thalamus and forms part of the nonspecific thalamocortical projection system and the internal circuit of the basal ganglia. However, the functional roles of this complex remain to be fully elucidated. Here we have e...

journal_title：Journal of neurophysiology

authors： Minamimoto T,Kimura M

更新日期：2002-06-01 00:00:00

abstract：:The anterior branch of N. VIII was sectioned in adult frogs. Two months later the brain was isolated to record in vitro responses in the vestibular nuclei and from the abducens nerves following electric stimulation of the anterior branch of N. VIII or of the posterior canal nerve. Extra- and intracellularly recorded r...

journal_title：Journal of neurophysiology

authors： Goto F,Straka H,Dieringer N

更新日期：2000-07-01 00:00:00

abstract：:Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM)...

journal_title：Journal of neurophysiology

authors： Bikson M,Baraban SC,Durand DM

更新日期：2002-01-01 00:00:00

abstract：:The electrical activity of 168 individual neurons located in the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis, and ventralis, has been recorded in precollicular decerebrate cats during sinusoidal tilt about the longitudinal axis of the whole...

journal_title：Journal of neurophysiology

authors： Manzoni D,Pompeiano O,Stampacchia G,Srivastava UC

更新日期：1983-11-01 00:00:00

abstract：:Using whole cell recordings, I analyzed the intrinsic discharge properties for 285 neurons in Rexed's laminae III-V of isolated hamster spinal cord preparations. Neurons were characterized by their responses to step-wise and ramp-hold depolarizing current applied through the recording pipettes. Tonic cells (133/285; 4...

journal_title：Journal of neurophysiology

authors： Schneider SP

更新日期：2003-07-01 00:00:00

abstract：:ALS (amyotrophic lateral sclerosis) is an adult-onset and deadly neurodegenerative disease characterized by a progressive and selective loss of motoneurons. Transgenic mice overexpressing a mutated human gene (G93A) coding for the enzyme SOD1 (Cu/Zn superoxide dismutase) develop a motoneuron disease resembling ALS in ...

journal_title：Journal of neurophysiology

authors： Kuo JJ,Schonewille M,Siddique T,Schults AN,Fu R,Bär PR,Anelli R,Heckman CJ,Kroese AB

更新日期：2004-01-01 00:00:00

abstract：:The increasing use of transgenic mice for the study of pain mechanisms necessitates comprehensive understanding of the murine somatosensory system. Using an in vivo mouse preparation, we studied response properties of tibial nerve afferent fibers innervating glabrous skin. Recordings were obtained from 225 fibers iden...

journal_title：Journal of neurophysiology

authors： Cain DM,Khasabov SG,Simone DA

更新日期：2001-04-01 00:00:00

abstract：:1. During alertness, lemniscal thalamocortical neurons in the ventral medial geniculate body (MGBv) encode sound signals by firing action potentials in a tonic mode. When they are in a burst firing mode, characteristic of thalamic neurons during some sleep states, the same stimuli may have an alerting function, leadin...

journal_title：Journal of neurophysiology

authors： Tennigkeit F,Schwarz DW,Puil E

更新日期：1996-12-01 00:00:00

abstract：:We hypothesized that epilepsy affects the activity of the autonomic nervous system even in the absence of seizures, which should manifest as differences in heart rate variability (HRV) and cardiac cycle. To test this hypothesis, we investigated ECG traces of 91 children and adolescents with generalized epilepsy and 25...

journal_title：Journal of neurophysiology

authors： Sivakumar SS,Namath AG,Tuxhorn IE,Lewis SJ,Galán RF

更新日期：2016-04-01 00:00:00

abstract：:1. Isolated, single-neuron extracellular potentials were recorded sequentially in area TE of the inferior temporal cortex (IT) of two macaque monkeys (n = 58 and n = 41 neurons). Data were obtained while the animals were performing a paired-associate task. The task utilized five stimuli and eight stimulus pairings (4 ...

journal_title：Journal of neurophysiology

authors： Gochin PM,Colombo M,Dorfman GA,Gerstein GL,Gross CG

更新日期：1994-06-01 00:00:00

abstract：:1. The effects of gamma-aminobutyric acid (GABA) and glycine and their respective antagonists were determined for neurons in the mouse superior olivary complex. Brain slices (400 microns) were cut in the frontal plane and maintained in an oxygenated saline solution for physiological recording. Recordings were made fro...

journal_title：Journal of neurophysiology

authors： Wu SH,Kelly JB

更新日期：1995-01-01 00:00:00

abstract：:In a recent study, Wang et al. (J Neurophysiol 113: 1989-2001, 2015) used a precision grip force control task to unveil the contribution of feedforward and feedback mechanisms to sensorimotor dysfunction in autism spectrum disorder (ASD). Impairment of both motor control mechanisms was observed, along with significant...

journal_title：Journal of neurophysiology

authors： Parma V,de Marchena AB

更新日期：2016-03-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:1. We studied the frequency responses of neurons in the nucleus ovoidalis (OV), the principal thalamic auditory relay nucleus of the chicken, in the subthreshold range of membrane potentials. The frequency response is the impedance amplitude profile evident in the voltage response to a broadband stimulus. The stimulus...

journal_title：Journal of neurophysiology

authors： Ströhmann B,Schwarz DW,Puil E

更新日期：1994-04-01 00:00:00

abstract：:We elicited repetitive discharge in hypoglossal motoneurons recorded in slices of rat brain stem using a combination of a suprathreshold injected current step with superimposed noise to mimic the synaptic drive likely to occur during physiological activation. The effects of repetitive en mass stimulation of afferent n...

journal_title：Journal of neurophysiology

authors： Türker KS,Powers RK

更新日期：1999-08-01 00:00:00

abstract：:We propose that the descending command from area 4 that is responsible, in part, for the change in limb trajectory required to step over an obstacle in one's path also plays a role in triggering the anticipatory postural modifications that accompany this movement. To test this hypothesis, we recorded the discharge cha...

journal_title：Journal of neurophysiology

authors： Kably B,Drew T

更新日期：1998-07-01 00:00:00

abstract：:Vibration reduces the amplitudes of the tendon jerk response and the Hoffmann and stretch reflexes in the muscle exposed to the vibration, yet does not alter the time to task failure when the task involves exerting a submaximal force against a rigid restraint. Because the amplitude of the stretch reflex is greater whe...

journal_title：Journal of neurophysiology

authors： Mottram CJ,Maluf KS,Stephenson JL,Anderson MK,Enoka RM

更新日期：2006-02-01 00:00:00

abstract：:Male zebra finches produce a song consisting of a canonical sequence of syllables, learned from a tutor and repeated throughout its adult life. Much of the neural circuitry responsible for this behavior is located in the cortical premotor region HVC (acronym is name). In a recent study from our laboratory, we found th...

journal_title：Journal of neurophysiology

authors： Galvis D,Wu W,Hyson RL,Johnson F,Bertram R

更新日期：2017-08-01 00:00:00

abstract：:Stress-related alterations to the induction of hippocampal synaptic plasticity have been implicated in certain forms of psychiatric disorders. However, relatively little is known about such changes in other psychiatric disorders-related structures. We tested this possibility in one of such structures, the nucleus accu...

journal_title：Journal of neurophysiology

authors： Hugues S,Kessal K,Hunt MJ,Garcia R

更新日期：2003-11-01 00:00:00