Cholecystokinin B-type receptors mediate a G-protein-dependent depolarizing action of sulphated cholecystokinin ocatapeptide (CCK-8s) on rodent neonatal spinal ventral horn neurons.

abstract：:1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is s...

journal_title：Journal of neurophysiology

authors： Rahamimoff R,Edry-Schiller J,Ginsburg S

更新日期：1992-12-01 00:00:00

abstract：:This study determined the effect of mixed (slip- and trip-like stance perturbation) training on reactive responses in people with chronic stroke (PwCS) and examined modulation of their reactive responses on higher intensity perturbations posttraining (scaling). Twelve PwCS were exposed to consecutive blocks of treadmi...

journal_title：Journal of neurophysiology

authors： Dusane S,Bhatt T

更新日期：2020-07-01 00:00:00

abstract：:Training rats to perform rapidly and efficiently in an olfactory discrimination task results in robust enhancement of excitatory and inhibitory synaptic connectivity in the rat piriform cortex, which is maintained for days after training. To explore the mechanisms by which such synaptic enhancement occurs, we recorded...

journal_title：Journal of neurophysiology

authors： Saar D,Reuveni I,Barkai E

更新日期：2012-02-01 00:00:00

abstract：:Few studies have analyzed activity-induced changes in EMG activity in individual human motor units. We studied the changes in human thenar motor unit EMG that accompany the potentiation of twitch force and fatigue of tetanic force. Single motor unit EMG and force were recorded in healthy subjects in response to select...

journal_title：Journal of neurophysiology

authors： Thomas CK,Johansson RS,Bigland-Ritchie B

更新日期：2006-03-01 00:00:00

abstract：:We have shown that some neural activity is required for the maintenance of long-term potentiation (LTP) at visual cortical inhibitory synapses. We tested whether this was also the case in N-methyl-d-aspartate (NMDA) receptor-independent LTP of excitatory connections in layer 2/3 cells of developing rat visual cortex. ...

journal_title：Journal of neurophysiology

authors： Liu HN,Kurotani T,Ren M,Yamada K,Yoshimura Y,Komatsu Y

更新日期：2004-08-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:Two forms of undulatory locomotion in the lamprey (a lower vertebrate) have been described earlier: fast forward swimming (FFS) used for long distance migrations and slow backward swimming (SBS) used for escape from adverse tactile stimuli. In the present study, we describe another form of escape behavior: slow forwar...

journal_title：Journal of neurophysiology

authors： Islam SS,Zelenin PV

更新日期：2008-01-01 00:00:00

abstract：:Many neurophysiological experiments involving monkeys require that the head be stabilized while the animal performs a task. Often a post is attached to the skull to accomplish this goal, using a headcap formed from dental acrylic. We describe a new headpost, developed by refinement of several prototypes, and supply an...

journal_title：Journal of neurophysiology

authors： Adams DL,Economides JR,Jocson CM,Horton JC

更新日期：2007-08-01 00:00:00

abstract：:Activation of calcium-calmodulin dependent protein kinase II (CaMKII) during induction of long-term potentiation (LTP) is a series of complicated stochastic processes that are affected by noise. There are two main sources of noise affecting CaMKII activation within a dendritic spine. One is the noise associated with s...

journal_title：Journal of neurophysiology

authors： Zeng S,Holmes WR

更新日期：2010-04-01 00:00:00

abstract：:Extraretinal information, such as corollary discharge (CD), is hypothesized to help compensate for saccade-induced visual input disruptions. However, support for this hypothesis is largely for one-dimensional transsaccadic visual changes, with little comprehensive information on the spatial characteristics. Here we sy...

journal_title：Journal of neurophysiology

authors： Jayet Bray LC,Bansal S,Joiner WM

更新日期：2016-03-01 00:00:00

abstract：:A stratified organization of visual, somatic and acoustic representations was observed in the cat SC. Cells of the superficial laminae were exclusively visual. Visual, somatic, and acoustic cells were observed in the intermediate laminae while the deeper laminae were predominantly nonvisual. A detailed examination of ...

journal_title：Journal of neurophysiology

authors： Stein BE,Magalhães-Castro B,Kruger L

更新日期：1976-03-01 00:00:00

abstract：:Homosynaptic long-term depression (LTD) of synaptic efficacy was induced in field excitatory postsynaptic potentials by administration of 900 pulses at either 1 or 3 Hz in 2- to 3-wk-old Sprague-Dawley rats. The stimulation was administered via a bipolar stimulating electrode placed immediately adjacent to the recordi...

journal_title：Journal of neurophysiology

authors： Christie BR,Schexnayder LK,Johnston D

更新日期：1997-03-01 00:00:00

abstract：:1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

journal_title：Journal of neurophysiology

authors： Andreasen M,Hablitz JJ

更新日期：1993-06-01 00:00:00

abstract：:Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used as a measure of neuronal activity, despite an incomplete understanding of the hemodynamic and neural bases for BOLD signals. Recent work by Lee and colleagues investigated whether activating genetically specified neuro...

journal_title：Journal of neurophysiology

authors： Palmer HS

更新日期：2010-10-01 00:00:00

abstract：:To examine mechanisms responsible for the long-term regulation of Ca2+-channels in an adult neuron, changes in whole cell Ba2+ current (IBa) were examined in adult bullfrog sympathetic ganglion B cells in vitro. Cells were cultured at low density in defined, serum free medium. After 15 days, total IBa was similar to t...

journal_title：Journal of neurophysiology

authors： Lei S,Dryden WF,Smith PA

更新日期：1997-12-01 00:00:00

abstract：:Odors activate lobster olfactory receptor neurons (ORNs) through phosphoinositide signaling that appears to target a Na(+)-gated nonselective cation channel. The Na(+)-gated channel is a potential member of the growing family of transient receptor potential (TRP) channels. Here, we test the effect of potential antagon...

journal_title：Journal of neurophysiology

authors： Bobkov YV,Ache BW

更新日期：2005-03-01 00:00:00

abstract：:Trimming all but two whiskers in adult rats produces a predictable change in cortical cell-evoked responses characterized by increased responsiveness to the two intact whiskers and decreased responsiveness to the trimmed whiskers. This type of synaptic plasticity in rat somatic sensory cortex, called "whisker pairing ...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Lu SM,Wiley RG,Ebner FF

更新日期：1998-06-01 00:00:00

abstract：:1. Antidromic stimulation of the visual radiation of cats has been used to investigate the possibility that some of the activity in principal geniculate cells following an optic tract stimulus is antidromic. Single spikes were selected from two classes of poststimulus activity to condition the antidromic test spike--t...

journal_title：Journal of neurophysiology

authors： Rosen AD,Vastola EF

更新日期：1977-01-01 00:00:00

abstract：:1. Brain ischemia causes excess release and accumulation of glutamate that binds to postsynaptic receptors. This opens ionotropic channels that mediate neuronal depolarization and ionic fluxes that can lead to neuronal death. 2. The CA1 pyramidal cell region of the hippocampus is particularly susceptible to this neuro...

journal_title：Journal of neurophysiology

authors： Andrew RD,Adams JR,Polischuk TM

更新日期：1996-10-01 00:00:00

abstract：:The ventrolateral preoptic nucleus (VLPO) is a key nucleus involved in the homeostatic regulation of sleep-wakefulness. Little is known, however, about the cellular mechanisms underlying its role in sleep regulation and how the neurotransmitters, such as GABA and noradrenaline (NA), are involved. In the present study ...

journal_title：Journal of neurophysiology

authors： Matsuo S,Jang IS,Nabekura J,Akaike N

更新日期：2003-03-01 00:00:00

abstract：:In the first visual synapse of the insect compound eye, both the presynaptic and postsynaptic signals are graded, nonspiking changes in membrane voltage. The synapse exhibits tonic transmitter release (even in dark) and strong adaptation to long-lasting light backgrounds, leading to changes also in the dynamics of sig...

journal_title：Journal of neurophysiology

authors： Uusitalo RO,Weckström M

更新日期：2000-04-01 00:00:00

abstract：:The induction of NMDA-receptor-dependent long-term potentiation (LTP) in adult CA1 is contingent on activation of Ca/calmodulin-dependent protein kinase II (CaMKII). However, little is known about kinase mediation of LTP in the dentate gyrus. In the present study, the involvement of the kinases CaMKII, PKA, and MAPK i...

journal_title：Journal of neurophysiology

authors： Wu J,Rowan MJ,Anwyl R

更新日期：2006-06-01 00:00:00

abstract：:Hyperphagia is common in diabetes and may worsen hyperglycemia and diabetic complications. The responsible mechanisms are not well understood. The hypothalamus is a key center for the control of appetite and energy homeostasis. The ventromedial nucleus (VMH) and arcuate nucleus (ARC) are two critical nuclei involved i...

journal_title：Journal of neurophysiology

authors： Li JY,Wu X,Lee A,Zhou SY,Owyang C

更新日期：2019-03-01 00:00:00

abstract：:Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, is caused by loss of the fragile X mental retardation protein (FMRP). FMRP is a negative regulator of local mRNA translation downstream of group 1 metabotropic glutamate receptor (Gp1 mGluR) activation. In the absence of FMRP there is...

journal_title：Journal of neurophysiology

authors： Auerbach BD,Bear MF

更新日期：2010-08-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the ef...

journal_title：Journal of neurophysiology

authors： Jang HJ,Cho KH,Park SW,Kim MJ,Yoon SH,Rhie DJ

更新日期：2012-01-01 00:00:00

abstract：:Autoinhibitory serotonin 1A receptors (5-HT(1A)) in dorsal raphé nucleus (DRN) have been implicated in chronic depression and in actions of selective serotonin reuptake inhibitors (SSRI). Due to experimental limitations, it was never studied at single-cell level whether changes in 5-HT(1A) receptor functionality occur...

journal_title：Journal of neurophysiology

authors： Cornelisse LN,Van der Harst JE,Lodder JC,Baarendse PJ,Timmerman AJ,Mansvelder HD,Spruijt BM,Brussaard AB

更新日期：2007-07-01 00:00:00

abstract：:Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Tobler PN,Taira M,Iijima T,Tsutsui K

更新日期：2009-06-01 00:00:00

abstract：:1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young rabbit hippocampal CA1 pyramidal cells in vitro. Various concentrations of nimodipine, ranging from 10 nM to 10 microM, were tested to investigate age- and concen...

journal_title：Journal of neurophysiology

authors： Moyer JR Jr,Thompson LT,Black JP,Disterhoft JF

更新日期：1992-12-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:Parallel recording of neuronal activity in the behaving animal is a prerequisite for our understanding of neuronal representation and storage of information. Here we describe the development of micro-machined silicon microelectrode arrays for unit and local field recordings. The two-dimensional probes with 96 or 64 re...

journal_title：Journal of neurophysiology

authors： Csicsvari J,Henze DA,Jamieson B,Harris KD,Sirota A,Barthó P,Wise KD,Buzsáki G

更新日期：2003-08-01 00:00:00