Differential modulation of single voltage-gated calcium channels by cholinergic and adrenergic agonists in adult hippocampal neurons.

abstract：:Controlled whisker stimulation and single-unit recordings were used to elucidate response transformations that occur during the processing of tactile information from ventral posterior medial thalamus (VPM) through cortical columns in the rat whisker/barrel cortex. Whiskers were either deflected alone, using punctate ...

journal_title：Journal of neurophysiology

authors： Brumberg JC,Pinto DJ,Simons DJ

更新日期：1999-10-01 00:00:00

abstract：:1. There is a long-standing debate about whether the large spiny cells in the hilar region of the hippocampus should be classified as pyramidal cells of Ammon's horn or as a distinct cell type of the dentate gyrus. The rationale for grouping these hilar neurons (termed "mossy cells") with pyramidal cells of Ammon's ho...

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Strowbridge BW,Schwartzkroin PA

更新日期：1993-10-01 00:00:00

abstract：:Whole cell membrane currents induced by the inflammatory mediators, bradykinin, 5-hydroxytryptamine (5-HT) and prostaglandin E2, were investigated in capsaicin-sensitive dorsal root ganglion (DRG) neurons from newborn rats grown on a monolayer of hippocampal glia without nerve growth factor (NGF). When firmly attached...

journal_title：Journal of neurophysiology

authors： Vyklický L,Knotková-Urbancová H,Vitásková Z,Vlachová V,Kress M,Reeh PW

更新日期：1998-02-01 00:00:00

abstract：:Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

journal_title：Journal of neurophysiology

authors： Gardner D,Ruff RL,White RL

更新日期：1984-01-01 00:00:00

abstract：:Both N-methyl-D-aspartate (NMDA) and quisqualate/AMPA-insensitive metabotropic glutamate (mGlu) receptors mediate plasticity induction in neocortex, but their interlaminar distribution in cortical microcircuits is largely unknown. We used (+)(3)H-MK801 and (3)H-glutamate binding plus saturating concentrations of NMDA,...

journal_title：Journal of neurophysiology

authors： Hedberg TG,Sperber EF,Velísková J,Moshé SL

更新日期：2000-10-01 00:00:00

abstract：:1. In four human subjects, we measured the latency of saccadic eye movements made to a second, eccentric target after an initial, foveated target was extinguished. In separate interleaved trails, the targets were either both stationary ("fixation") or both moving with the same velocity ("pursuit"). For both fixation a...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ,Miles FA

更新日期：1996-12-01 00:00:00

abstract：:Mechanisms that could mitigate the effects of hypoxia on neuronal signaling are incompletely understood. We show that axonal performance of a locust visual interneuron varied depending on oxygen availability. To induce hypoxia, tracheae supplying the thoracic nervous system were surgically lesioned and action potentia...

journal_title：Journal of neurophysiology

authors： Money TG,Sproule MK,Cross KP,Robertson RM

更新日期：2016-09-01 00:00:00

abstract：:1. Eye movements were recorded before and after bilateral occipital lobectomy in six rhesus monkeys trained to fixate and to follow small targets. Striate cortex was completely removed in two animals; small islands islands remained in the others. In all animals portions of extrastriate cortex were also removed but the...

journal_title：Journal of neurophysiology

authors： Zee DS,Tusa RJ,Herdman SJ,Butler PH,Gücer G

更新日期：1987-10-01 00:00:00

abstract：:Animals and human beings sense and react to real/potential dangerous stimuli. However, the supraspinal mechanisms relating noxious sensing and nocifensive behavior are mostly unknown. The collateralization and spatial organization of interrelated neurons are important determinants of coordinated network function. Here...

journal_title：Journal of neurophysiology

authors： Leiras R,Martín-Cora F,Velo P,Liste T,Canedo A

更新日期：2016-01-01 00:00:00

abstract：:This study examined the influence of proprioceptive input from hip flexor muscles on the activity in hip flexors during the swing phase of walking in the decerebrate cat. One hindlimb was partially denervated to remove cutaneous input and afferent input from most other hindlimb muscles. Perturbations to hip movement w...

journal_title：Journal of neurophysiology

authors： Lam T,Pearson KG

更新日期：2001-09-01 00:00:00

abstract：:Many critically ill patients in intensive care units suffer from an infection-induced whole body inflammatory state known as sepsis, which causes severe weakness in patients who survive. The mechanisms by which sepsis triggers intensive care unit-acquired weakness (ICUAW) remain unclear. Currently, research into ICUAW...

journal_title：Journal of neurophysiology

authors： Nardelli P,Khan J,Powers R,Cope TC,Rich MM

更新日期：2013-04-01 00:00:00

abstract：:Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo. J. Neurophysiol. 80: 2860-2869, 1998. The spontaneous activities, evoked synaptic responses, and membrane properties of CA3 pyramidal neurons and dentate granule cells in rat hippocampus were compared...

journal_title：Journal of neurophysiology

authors： Gao TM,Howard EM,Xu ZC

更新日期：1998-12-01 00:00:00

abstract：:Transection of a peripheral nerve results in withdrawal of synapses from motoneurons. Some of the withdrawn synapses are restored spontaneously, but those containing the vesicular glutamate transporter 1 (VGLUT1), and arising mainly from primary afferent neurons, are withdrawn permanently. If animals are exercised imm...

journal_title：Journal of neurophysiology

authors： Brandt J,Evans JT,Mildenhall T,Mulligan A,Konieczny A,Rose SJ,English AW

更新日期：2015-04-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:This study investigated the influence of different modalities of target information (visual, kinesthetic) on the accuracy, kinematics, and interjoint coordination of pointing movements to remembered targets. The targets were presented by a robot arm in five locations in three-dimensional (3D) space, either as a point ...

journal_title：Journal of neurophysiology

authors： Adamovich SV,Berkinblit MB,Fookson O,Poizner H

更新日期：1998-06-01 00:00:00

abstract：:Motor cortex plays a substantial role in driving movement, yet the details underlying this control remain unresolved. We analyzed the extent to which movement-related information could be extracted from single-trial motor cortical activity recorded while monkeys performed center-out reaching. Using information theoret...

journal_title：Journal of neurophysiology

authors： Golub MD,Yu BM,Schwartz AB,Chase SM

更新日期：2014-07-15 00:00:00

abstract：:In human spinal cord injury (SCI), imposed unilateral hip movements trigger multijoint, coordinated reflexes that might incorporate interneuronal circuitry involved in normal motor control, such as neural pathways associated with the reflex control of locomotion. To further investigate the complexity of these hip-trig...

journal_title：Journal of neurophysiology

authors： Onushko T,Schmit BD

更新日期：2007-10-01 00:00:00

abstract：:An inhibitory role for strychnine-sensitive glycine-gated chloride channels (GlyRs) in mature hippocampus is beginning to be appreciated. We have reported previously that CA1 pyramidal cells and GABAergic interneurons recorded in 3- to 4-wk-old rat hippocampal slices express functional GlyRs, dispelling previous misco...

journal_title：Journal of neurophysiology

authors： Song W,Chattipakorn SC,McMahon LL

更新日期：2006-04-01 00:00:00

abstract：:A number of studies have indicated an important role for N-methyl-D-aspartate (NMDA) receptors in cell survival versus cell death decisions during neuronal development, trauma, and ischemia. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all three of these c...

journal_title：Journal of neurophysiology

authors： de Rivero Vaccari JC,Corriveau RA,Belousov AB

更新日期：2007-11-01 00:00:00

abstract：:Male zebra finches produce a song consisting of a canonical sequence of syllables, learned from a tutor and repeated throughout its adult life. Much of the neural circuitry responsible for this behavior is located in the cortical premotor region HVC (acronym is name). In a recent study from our laboratory, we found th...

journal_title：Journal of neurophysiology

authors： Galvis D,Wu W,Hyson RL,Johnson F,Bertram R

更新日期：2017-08-01 00:00:00

abstract：:Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

journal_title：Journal of neurophysiology

authors： Bergey GK,Bigalke H,Nelson PG

更新日期：1987-01-01 00:00:00

abstract：:Eigenmannia, a genus of weakly electric fish, exhibits a specialized behavior known as the jamming avoidance response (JAR). The JAR results in a categorical difference between Eigenmannia that are in groups of conspecifics and those that are alone. Fish in groups exhibit the JAR behavior and thereby experience ongoin...

journal_title：Journal of neurophysiology

authors： Ramcharitar JU,Tan EW,Fortune ES

更新日期：2006-11-01 00:00:00

abstract：:1. We define an extrinsic frame of reference to represent the location of a point in extrapersonal space relative to a human subject's shoulder, and we define an intrinsic frame of reference to represent the orientation of the arm and forearm. 2. We examined the relations between coordinates in the extrinsic and intri...

journal_title：Journal of neurophysiology

authors： Soechting JF,Flanders M

更新日期：1989-08-01 00:00:00

abstract：:1. The functional organization of interneurons in spinal laminae III-V was studied in an isolated preparation of hamster dorsal horn with sensory innervation from an excised skin patch. Morphological details of 40 neurons were visualized by intracellular injection of horseradish peroxidase. Active and passive membrane...

journal_title：Journal of neurophysiology

authors： Schneider SP

更新日期：1992-11-01 00:00:00

abstract：:As a vital skill in an evolving world, interception of moving objects relies on accurate prediction of target motion. In natural circumstances, active gaze shifts often accompany hand movements when exploring targets of interest, but how eye and hand movements are coordinated during manual interception and their depen...

journal_title：Journal of neurophysiology

authors： Li Y,Wang Y,Cui H

更新日期：2018-01-01 00:00:00

abstract：:The contribution of ascending afferents to the control of speech movement was evaluated by applying unanticipated loads to the lower lip during the generation of combined upper lip-lower lip speech gestures. To eliminate potential contamination due to anticipation or adaptation, loads were applied randomly on only 10-...

journal_title：Journal of neurophysiology

authors： Abbs JH,Gracco VL

更新日期：1984-04-01 00:00:00

abstract：:Sustained oscillations of 13-18 Hz were observed in local field potentials (LFPs) in the cerebellar cortex of a behaving monkey. These oscillations, which appeared to be generated in the granular cell layer, were particularly prominent in the paramedian lobule. The oscillatory activity decreased during drowsiness or e...

journal_title：Journal of neurophysiology

authors： Pellerin JP,Lamarre Y

更新日期：1997-12-01 00:00:00

abstract：:Although species-specific differences in ion channel properties are well-documented, little has been known about the properties of the human Nav1.8 channel, an important contributor to pain signaling. Here we show, using techniques that include voltage clamp, current clamp, and dynamic clamp in dorsal root ganglion (D...

journal_title：Journal of neurophysiology

authors： Han C,Estacion M,Huang J,Vasylyev D,Zhao P,Dib-Hajj SD,Waxman SG

更新日期：2015-05-01 00:00:00

abstract：:1. Patterns of respiratory neuronal activity were examined in pentobarbitone anesthetized adult cats in a circumscribed area of the ventrolateral medulla, which has previously been defined as the pre-Bötzinger complex (pre-BOTC) from electrophysiological and morphological criteria in the brain stem-spinal cord prepara...

journal_title：Journal of neurophysiology

authors： Schwarzacher SW,Smith JC,Richter DW

更新日期：1995-04-01 00:00:00

abstract：:Internally generated, spontaneous activity is ubiquitous in the cortex, yet it does not appear to have a significant negative impact on sensory processing. Various studies have found that stimulus onset reduces the variability of cortical responses, but the characteristics of this suppression remained unexplored. By r...

journal_title：Journal of neurophysiology

authors： White B,Abbott LF,Fiser J

更新日期：2012-11-01 00:00:00