Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin.

abstract：:Altered activity of the entopeduncular nucleus, the rodent homologue of the globus pallidus internal segment in primates, is thought to mediate behavioral consequences of midbrain dopamine depletion in rodents. Few studies, however, have examined dopaminergic modulation of spiking activity in this nucleus. This study ...

journal_title：Journal of neurophysiology

authors： Ruskin DN,Bergstrom DA,Walters JR

更新日期：2002-07-01 00:00:00

abstract：:1. The neurophysiological basis for the sensation of prickle evoked by contact of some fabrics with the skin is reported. 2. Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle. These recordings showed that all low-threshold mec...

journal_title：Journal of neurophysiology

authors： Garnsworthy RK,Gully RL,Kenins P,Mayfield RJ,Westerman RA

更新日期：1988-04-01 00:00:00

abstract：:Previous studies using advanced matrix factorization techniques have shown that the coordination of human voluntary limb movements may be accomplished using combinations of a small number of intermuscular coordination patterns, or muscle synergies. However, the potential use of muscle synergies for isometric force gen...

journal_title：Journal of neurophysiology

authors： Roh J,Rymer WZ,Beer RF

更新日期：2012-04-01 00:00:00

abstract：:Paired associative stimulation (PAS) based on Hebb's law of association can induce plastic changes in the intact human. The optimal interstimulus interval (ISI) between the peripheral nerve and transcranial magnetic stimulus is not known for muscles of the lower leg. The aims of this study were to investigate the effe...

journal_title：Journal of neurophysiology

authors： Mrachacz-Kersting N,Fong M,Murphy BA,Sinkjaer T

更新日期：2007-03-01 00:00:00

abstract：:The ionic mechanisms underlying the termination of action-potential (AP) bursts and postburst afterhyperpolarization (AHP) in intrinsically bursting (IB) neocortical neurons were investigated by performing intracellular recordings in thin slices of rat sensorimotor cortex. The blockade of Ca(2+)-activated K(+) current...

journal_title：Journal of neurophysiology

authors： Franceschetti S,Lavazza T,Curia G,Aracri P,Panzica F,Sancini G,Avanzini G,Magistretti J

更新日期：2003-04-01 00:00:00

abstract：:To trigger action potentials in neurons, most investigators use electrical or chemical stimulation. Here we describe an optical stimulation method based on semi-synthetic light-activated ion channels. These SPARK (synthetic photoisomerizable azobenzene-regulated K(+)) channels consist of a synthetic azobenzene-contain...

journal_title：Journal of neurophysiology

authors： Chambers JJ,Banghart MR,Trauner D,Kramer RH

更新日期：2006-11-01 00:00:00

abstract：:The aim of this study was to examine how cat spinal motoneurons integrate the synaptic currents generated by the concurrent activation of large groups of presynaptic neurons. We obtained intracellular recordings from cat triceps surae motoneurons and measured the effects of repetitive activity in different sets of pre...

journal_title：Journal of neurophysiology

authors： Powers RK,Binder MD

更新日期：2000-01-01 00:00:00

abstract：:1. The discharges from individual Golgi tendon organs of peroneus tertius and brevis muscles were recorded in anesthetized cats. Responses to unfused isometric contractions of single motor units and combinations of motor units were compared with responses to contractions eliciting muscle shortening (i.e., shortening c...

journal_title：Journal of neurophysiology

authors： Horcholle-Bossavit G,Jami L,Petit J,Vejsada R,Zytnicki D

更新日期：1988-05-01 00:00:00

abstract：:1. Whole-cell recordings were performed on acutely isolated pyramidal neurons from rat sensorimotor cortex 2 to 21 days postnatal to study the expression of a tetrodotoxin (TTX) sensitive, voltage dependent, persistent Na+ current (INaP) during different stages of postnatal development. 2. INaP was activated positive ...

journal_title：Journal of neurophysiology

authors： Alzheimer C,Schwindt PC,Crill WE

更新日期：1993-01-01 00:00:00

abstract：:The medial superior temporal area of the macaque monkey extrastriate visual cortex can be divided into a dorsal medial (MSTd) and a lateral ventral (MSTl) region. The functions of the two regions may not be identical: MSTd may process optic flow information that results from the movement of the observer, whereas MSTl ...

journal_title：Journal of neurophysiology

authors： Eifuku S,Wurtz RH

更新日期：1998-07-01 00:00:00

abstract：:CA1 place cells become more anticipatory with experience, an effect thought to be caused by NMDA receptor-dependent plasticity in the CA3-CA1 network. Theta (~5-12 Hz), slow gamma (~25-50 Hz), and fast gamma (~50-100 Hz) rhythms are thought to route spatial information in the hippocampal formation and to coordinate pl...

journal_title：Journal of neurophysiology

authors： Gereke BJ,Mably AJ,Colgin LL

更新日期：2018-02-01 00:00:00

abstract：:Primates have a remarkable ability to perceive, recognize, and discriminate among the plethora of people, places, and things that they see, and neural selectivity in the primate inferotemporal (IT) cortex is thought to underlie this ability. Here we investigated the relationship between neural response and perception ...

journal_title：Journal of neurophysiology

authors： Allred S,Liu Y,Jagadeesh B

更新日期：2005-12-01 00:00:00

abstract：:To determine whether visual discrimination in macaque frontal eye field (FEF) is contingent on saccade planning, unit activity was recorded in two monkeys during blocked go and no-go visual search trials. The eye movements made by monkeys after correct no-go trials, in addition to an attenuation of the visual response...

journal_title：Journal of neurophysiology

authors： Thompson KG,Bichot NP,Schall JD

更新日期：1997-02-01 00:00:00

abstract：:It is well recognized that the brain uses sensory information to accurately produce motor commands. Indeed, most research into the relationship between sensory and motor systems has focused on how sensory information modulates motor function. In contrast, recent studies have begun to investigate the reverse: how senso...

journal_title：Journal of neurophysiology

authors： Wong JD,Wilson ET,Gribble PL

更新日期：2011-05-01 00:00:00

abstract：:The medial division of the ventral nucleus of the lateral lemniscus (VNLLm) contains a specialized population of neurons that is sensitive to interaural temporal disparities (ITDs), a potent cue for sound localization along the azimuth. Unlike many ITD-sensitive neurons elsewhere in the auditory system, neurons in the...

journal_title：Journal of neurophysiology

authors： Batra R,Fitzpatrick DC

更新日期：2002-08-01 00:00:00

abstract：:Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. J. Neurophysiol. 78: 2707-2716, 1997. The relationship between paired-pulse facilitation (PPF) and synaptic potentiation induced by various protocols and their cellular and molecular mechanisms were exam...

journal_title：Journal of neurophysiology

authors： Wang JH,Kelly PT

更新日期：1997-11-01 00:00:00

abstract：:The purpose of this study was to quantify the long-term loss of independent finger movements in humans with lesions relatively restricted to motor cortex or corticospinal tract. We questioned whether damage to the motor cortex or corticospinal tract would permanently affect the ability to move each finger to the same ...

journal_title：Journal of neurophysiology

authors： Lang CE,Schieber MH

更新日期：2003-08-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:In the spinal cord, the monoamine neurotransmitter norepinephrine, which is released mainly from fibers descending from the dorsal pons, has major modulatory effects on nociception and locomotor rhythms. To map the spatial and temporal patterns of this release, changes in monoamine level were examined in laminae I-VII...

journal_title：Journal of neurophysiology

authors： Hentall ID,Mesigil R,Pinzon A,Noga BR

更新日期：2003-06-01 00:00:00

abstract：:Coupled oscillatory activity recorded between sensorimotor regions of the basal ganglia-thalamocortical loop is thought to reflect information transfer relevant to movement. A neuronal firing-rate model of basal ganglia-thalamocortical circuitry, however, has dominated thinking about basal ganglia function for the pas...

journal_title：Journal of neurophysiology

authors： Lipski WJ,Wozny TA,Alhourani A,Kondylis ED,Turner RS,Crammond DJ,Richardson RM

更新日期：2017-09-01 00:00:00

abstract：:1. The role of sensory information in shaping muscle activation patterns to postural perturbations in humans was investigated by varying velocity, amplitude, or duration of the perturbing stimulus. Ten normal subjects were exposed to 120 backward translations of the support surface under conditions of varying velociti...

journal_title：Journal of neurophysiology

authors： Diener HC,Horak FB,Nashner LM

更新日期：1988-06-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:In layer 2/3 of neocortex, brief trains of action potentials in pyramidal neurons (PNs) induce the mobilization of endogenous cannabinoids (eCBs), resulting in a depression of GABA release from the terminals of inhibitory interneurons (INs). This depolarization-induced suppression of inhibition (DSI) is mediated by ac...

journal_title：Journal of neurophysiology

authors： Lemtiri-Chlieh F,Levine ES

更新日期：2007-11-01 00:00:00

abstract：:In adult songbirds, auditory neurons in the primary auditory forebrain region of field L and a secondary auditory forebrain region of caudal mesopallium (CM) are highly responsive to natural sounds, such as conspecific song. Because these nuclei are involved in sensory representations of songs, we investigated how the...

journal_title：Journal of neurophysiology

authors： Amin N,Doupe A,Theunissen FE

更新日期：2007-05-01 00:00:00

abstract：:Somatic sensory neurons of the dorsal root ganglia are necessary for a large part of our mechanosensory experience. However, we only have a good knowledge of the molecules required for mechanotransduction in simple invertebrates such as the nematode Caenorhabiditis elegans. In C. elegans, a number of so-called mec gen...

journal_title：Journal of neurophysiology

authors： Martinez-Salgado C,Benckendorff AG,Chiang LY,Wang R,Milenkovic N,Wetzel C,Hu J,Stucky CL,Parra MG,Mohandas N,Lewin GR

更新日期：2007-12-01 00:00:00

abstract：:The retinal image of visual objects can vary drastically with changes of viewing angle. Nevertheless, our visual system is capable of recognizing objects fairly invariant of viewing angle. Under natural viewing conditions, different views of the same object tend to occur in temporal proximity, thereby generating tempo...

journal_title：Journal of neurophysiology

authors： Michler F,Eckhorn R,Wachtler T

更新日期：2009-08-01 00:00:00

abstract：:1. Reflex responses were elicited in muscles that act at the ankle by electrical stimulation of low-threshold afferents from the foot in human subjects who were reclining supine. During steady voluntary contractions, stimulus trains (5 pulses at 300 Hz) were delivered at two intensities to the sural nerve (1.2-4.0 tim...

journal_title：Journal of neurophysiology

authors： Aniss AM,Gandevia SC,Burke D

更新日期：1992-05-01 00:00:00

abstract：:1. Intracellular and extracellular recordings were obtained from ganglion cells in the rabbit retina. The effect of N-methyl-DL-aspartate (NMDLA) and N-methyl-D-aspartate (NMDA) antagonists were studied with the use of a perfusion method for drug application. 2. NMDLA excited all ganglion cell types and caused a chara...

journal_title：Journal of neurophysiology

authors： Massey SC,Miller RF

更新日期：1990-01-01 00:00:00

abstract：:1. Transmission at electrical synapses is modulated by a variety of physiological signals, and this modulation is a potentially general mechanism for regulating signal integration in neural circuits and networks. In the outer plexiform layer of the retina, modulation of horizontal-cell electrical coupling by dopamine ...

journal_title：Journal of neurophysiology

authors： McMahon DG,Brown DR

更新日期：1994-11-01 00:00:00

abstract：:1. The horizontal eye movements induced by acceleration along the interaural axis were recorded from five monkeys (Macaca mulatta) by the use of the electromagnetic search-coil technique. Animals sat on a sled that was moved briefly in darkness along a linear track (bell-shaped acceleration profile: peak, 400 mm/s2; d...

journal_title：Journal of neurophysiology

authors： Schwarz U,Miles FA

更新日期：1991-09-01 00:00:00