Suppression of cortical neural variability is stimulus- and state-dependent.

abstract：:Many electrophysiologists view neurotransmitter transporters as tiny vacuum cleaners, operating continuously to lower extracellular neurotransmitter concentration to zero. However, this is not consistent with their known behavior, instead only reducing extracellular neurotransmitter concentration to a finite, nonzero ...

journal_title：Journal of neurophysiology

authors： Richerson GB,Wu Y

更新日期：2003-09-01 00:00:00

abstract：:Organization of spinal motor output has become of interest for investigating differential activation of lumbar and sacral motor pools during locomotor tasks. Motor pools are associated with functional grouping of motoneurons of the lower limb muscles. Here we examined how the spatiotemporal organization of lumbar and ...

journal_title：Journal of neurophysiology

authors： Dewolf AH,Ivanenko YP,Zelik KE,Lacquaniti F,Willems PA

更新日期：2019-08-01 00:00:00

abstract：:Whole cell patch-clamp recordings were used to investigate the contribution of transient, low-threshold calcium currents (I(T)) to firing properties of hamster spinal dorsal horn neurons. I(T) was widely, though not uniformly, expressed by cells in Rexed's laminae I-IV and correlated with the pattern of action potenti...

journal_title：Journal of neurophysiology

authors： Ku WH,Schneider SP

更新日期：2011-11-01 00:00:00

abstract：:Dopamine (DA) neurons and GABA neurons of the substantia nigra (SN) promote distinct functions in the control of movement and have different firing properties and action potential (AP) waveforms. APs recorded from DA and GABA neurons differed in amplitude, maximal rate of rise, and duration. In addition, the threshold...

journal_title：Journal of neurophysiology

authors： Seutin V,Engel D

更新日期：2010-06-01 00:00:00

abstract：:We have used electrophysiological techniques to document segmental differences in the pathways between the giant, escape command axons, lateral giants (LG) and medial giants (MG), and the nongiant, fast flexor (FF) motoneurons. We found no difference in the input from LG and MG axons to FF motoneurons in the posterior...

journal_title：Journal of neurophysiology

authors： Miller LA,Hagiwara G,Wine JJ

更新日期：1985-01-01 00:00:00

abstract：:Two identified locust neurons, the lobula giant movement detector (LGMD) and its postsynaptic partner, the descending contralateral movement detector (DCMD), constitute one motion-sensitive pathway in the visual system that responds preferentially to objects that approach on a direct collision course and are implicate...

journal_title：Journal of neurophysiology

authors： McMillan GA,Gray JR

更新日期：2012-08-01 00:00:00

abstract：:Primary auditory cortex (A1) neurons are believed not to carry much information about tonal offsets because A1 neurons in barbiturate-anesthetized animals are usually described as having only onset responses. We investigated tonal offset responses in comparison with onset responses in the caudal part of A1 of awake ca...

journal_title：Journal of neurophysiology

authors： Qin L,Chimoto S,Sakai M,Wang J,Sato Y

更新日期：2007-05-01 00:00:00

abstract：:Smooth pursuit eye movements are driven by retinal motion signals. These retinal motion signals are converted into motor commands that obey Listing's law (i.e., no accumulation of ocular torsion). The fact that smooth pursuit follows Listing's law is often taken as evidence that no explicit reference frame transformat...

journal_title：Journal of neurophysiology

authors： Blohm G,Lefèvre P

更新日期：2010-10-01 00:00:00

abstract：:Because the subthalamic nucleus (STN) acts as a driving force of the basal ganglia, it is important to know how the activities of STN neurons are regulated. Previously, we have reported that a subset of STN neurons generates a plateau potential in a voltage-dependent manner. These plateau potentials can be evoked only...

journal_title：Journal of neurophysiology

authors： Otsuka T,Abe T,Tsukagawa T,Song WJ

更新日期：2004-07-01 00:00:00

abstract：:Here we report on the development of a novel neuroelectronic interface consisting of an array of noninvasive gold-mushroom-shaped microelectrodes (gMmicroEs) that practically provide intracellular recordings and stimulation of many individual neurons, while the electrodes maintain an extracellular position. The develo...

journal_title：Journal of neurophysiology

authors： Hai A,Shappir J,Spira ME

更新日期：2010-07-01 00:00:00

abstract：:Parallel recording of neuronal activity in the behaving animal is a prerequisite for our understanding of neuronal representation and storage of information. Here we describe the development of micro-machined silicon microelectrode arrays for unit and local field recordings. The two-dimensional probes with 96 or 64 re...

journal_title：Journal of neurophysiology

authors： Csicsvari J,Henze DA,Jamieson B,Harris KD,Sirota A,Barthó P,Wise KD,Buzsáki G

更新日期：2003-08-01 00:00:00

abstract：:The transient potassium current (I(A)) plays an important role in shaping the firing properties of pyloric neurons in the stomatogastric ganglion (STG) of the spiny lobster, Panulirus interruptus. The shal gene encodes I(A) in pyloric neurons. However, when we over-expressed the lobster Shal protein by shal RNA inject...

journal_title：Journal of neurophysiology

authors： Zhang Y,MacLean JN,An WF,Lanning CC,Harris-Warrick RM

更新日期：2003-04-01 00:00:00

abstract：:The contributions of the hyperpolarization-activated current, I(h), to generation of rhythmic activities are well described for various central neurons, particularly in thalamocortical circuits. In the present study, we investigated effects of a general anesthetic, propofol, on native I(h) in neurons of thalamus and c...

journal_title：Journal of neurophysiology

authors： Chen X,Shu S,Bayliss DA

更新日期：2005-12-01 00:00:00

abstract：:Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...

journal_title：Journal of neurophysiology

authors： Currie KP,Fox AP

更新日期：2000-03-01 00:00:00

abstract：:Weight predictions used to scale lifting forces adapt quickly when repeatedly lifting unusually weighted objects and are readily updated by explicit information provided about weight. In contrast, weight predictions used when making perceptual judgments about weight are more resistant to change and are largely unaffec...

journal_title：Journal of neurophysiology

authors： Trewartha KM,Flanagan JR

更新日期：2016-09-01 00:00:00

abstract：:Primates can generate accurate, smooth eye-movement responses to moving target objects of arbitrary shape and size, even in the presence of complex backgrounds and/or the extraneous motion of non-target objects. Most previous studies of pursuit have simply used a spot moving over a featureless background as the target...

journal_title：Journal of neurophysiology

authors： Masson GS,Stone LS

更新日期：2002-11-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:In the inferior colliculus (IC) of the big brown bat, a subpopulation of cells ( approximately 35%) are tuned to a narrow range of sound durations. Band-pass tuning for sound duration has not been seen at lower levels of the auditory pathway. Previous work suggests that it arises at the IC through the interaction of s...

journal_title：Journal of neurophysiology

authors： Casseday JH,Ehrlich D,Covey E

更新日期：2000-09-01 00:00:00

abstract：:1. Using patch-clamp recordings, expression of voltage-activated ion channels by identified glial cells in situ was studied in hippocampal slices derived from 5- to 24-day-old rats. Glial cells were filled with Lucifer yellow during recording, and were identified by staining for glial fibrillary acidic protein (GFAP)....

journal_title：Journal of neurophysiology

authors： Sontheimer H,Waxman SG

更新日期：1993-11-01 00:00:00

abstract：:To explore the effects of acoustic and behavioral context on neuronal responses in the core of auditory cortex (fields A1 and R), two monkeys were trained on a go/no-go discrimination task in which they learned to respond selectively to a four-note target (S+) melody and withhold response to a variety of other nontarg...

journal_title：Journal of neurophysiology

authors： Yin P,Mishkin M,Sutter M,Fritz JB

更新日期：2008-12-01 00:00:00

abstract：:Speech stimuli give rise to neural activity in the listener that can be observed as waveforms using magnetoencephalography. Although waveforms vary greatly from trial to trial due to activity unrelated to the stimulus, it has been demonstrated that spoken sentences can be discriminated based on theta-band (3-7 Hz) pha...

journal_title：Journal of neurophysiology

authors： Howard MF,Poeppel D

更新日期：2010-11-01 00:00:00

abstract：:To localize objects relative to ourselves, we need to combine various sensory and motor signals. When these signals change abruptly, as information about eye orientation does during saccades, small differences in latency between the signals could introduce localization errors. We examine whether independent temporal i...

journal_title：Journal of neurophysiology

authors： Maij F,Brenner E,Smeets JB

更新日期：2009-07-01 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00

abstract：:Synaptic transmission throughout most of the CNS is steeply dependent on presynaptic calcium influx through the voltage-gated calcium channels Cav2.1-Cav2.3. In addition to triggering exocytosis, this calcium influx also recruits short-term synaptic plasticity. During the complex patterns of presynaptic activity that ...

journal_title：Journal of neurophysiology

authors： Ricoy UM,Frerking ME

更新日期：2014-06-15 00:00:00

abstract：:The current eye-tracking study examined the influence of reward on oculomotor performance, and the extent to which learned stimulus-reward associations interacted with voluntary oculomotor control with a modified paradigm based on the classical antisaccade task. Participants were shown two equally salient stimuli simu...

journal_title：Journal of neurophysiology

authors： Preciado D,Theeuwes J

更新日期：2018-10-01 00:00:00

abstract：:1. A characteristic plateau pattern was observed in the rate of afferent discharges during ramp-and-hold stretch of spindles isolated from semitendinosus muscles of frogs. The plateau pattern was more frequent in summer frogs (84%) than winter frogs (11%). 2. The plateau pattern consisted of a discharge rate around 12...

journal_title：Journal of neurophysiology

authors： Sokabe M,Nunogaki K,Naruse K,Soga H,Fujitsuka N,Yoshimura A,Ito F

更新日期：1993-07-01 00:00:00

abstract：:1. In order to investigate the effects of an imbalance in stimulation to the eyes without the confounding influence of continuous deprivation of one eye, we reared cats with unequal alternating monocular exposure (AME) and, for comparison, cats with equal AME. We recorded extracellularly from single cells in area 17 o...

journal_title：Journal of neurophysiology

authors： Tieman DG,McCall MA,Hirsch HV

更新日期：1983-03-01 00:00:00

abstract：:The medial olivocochlear (MOC) efferent system, which innervates cochlear outer hair cells, suppresses cochlear responses. MOC-mediated suppression includes both slow and fast components, with time courses differing by three orders of magnitude. Pharmacological studies in anesthetized guinea pigs suggest that both slo...

journal_title：Journal of neurophysiology

authors： Yoshida N,Liberman MC,Brown MC,Sewell WF

更新日期：1999-12-01 00:00:00

abstract：:The effect of acute intrahippocampal infusion of brain-derived neurotrophic factor (BDNF) on synaptic transmission in the dentate gyrus was investigated in urethan-anesthetized rats. Medial perforant path-evoked field potentials were recorded in the dentate hilus and BDNF-containing buffer was infused (4 microl, 25 mi...

journal_title：Journal of neurophysiology

authors： Messaoudi E,Bârdsen K,Srebro B,Bramham CR

更新日期：1998-01-01 00:00:00

abstract：:It is well known that, typically, saccadic eye movements precede goal-directed hand movements to a visual target stimulus. Also pointing in general is more accurate when the pointing target is gazed at. In this study, it is hypothesized that saccades are not only preceding pointing but that gaze also is stabilized dur...

journal_title：Journal of neurophysiology

authors： Neggers SF,Bekkering H

更新日期：2000-02-01 00:00:00