Dynamic equilibrium of neurotransmitter transporters: not just for reuptake anymore.

abstract：:Recent work has implicated low-frequency (<20 Hz) neuronal phase information as important for both auditory (<10 Hz) and speech [theta (∼4-8 Hz)] perception. Activity on the timescale of theta corresponds linguistically to the average length of a syllable, suggesting that information within this range has consequences...

journal_title：Journal of neurophysiology

authors： Cogan GB,Poeppel D

更新日期：2011-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...

journal_title：Journal of neurophysiology

authors： Charkviani M,Muradashvili N,Sulimai N,Lominadze D

更新日期：2020-08-01 00:00:00

abstract：:The mechanisms behind the therapeutic effects of electrical stimulation of the brain in epilepsy and other disorders are poorly understood. Previous studies in vitro have shown that uniform electric fields can suppress epileptiform activity through a direct polarizing effect on neuronal membranes. Such an effect depen...

journal_title：Journal of neurophysiology

authors： Mikkelsen R,Andreasen M,Nedergaard S

更新日期：2013-06-01 00:00:00

abstract：:The mouse is an important model system for understanding the molecular basis of neuronal signaling and diseases of synaptic communication. However, the best-characterized retinal ribbon-style synapses are those of nonmammalian vertebrates. To remedy this situation, we asked whether it would be feasible to track synapt...

journal_title：Journal of neurophysiology

authors： Zhou ZY,Wan QF,Thakur P,Heidelberger R

更新日期：2006-11-01 00:00:00

abstract：:To probe the mechanism of visual suppression, we have raised macaques with strabismus by disinserting the medial rectus muscle in each eye at 1 mo of age. Typically, this operation produces a comitant, alternating exotropia with normal acuity in each eye. Here we describe an unusual occurrence: the development of seve...

journal_title：Journal of neurophysiology

authors： Adams DL,Economides JR,Horton JC

更新日期：2015-05-01 00:00:00

abstract：:Consummatory feeding behaviors in Aplysia californica are controlled by a polymorphic central pattern generator (CPG) circuit. Previous investigations have demonstrated colocalization of markers for GABA and catecholamines within two interneurons, B20 and B65, that participate in configuring the functional output of t...

journal_title：Journal of neurophysiology

authors： Díaz-Ríos M,Miller MW

更新日期：2005-04-01 00:00:00

abstract：:1. The aims of this study were 1) to determine whether the impulse activity in rabbit aortic baroreceptors (BRs) was influenced by changes in nonpulsatile flow through the aortic lumen and 2) to examine the BR and aortic arch responses to changes in temperature. 2. An in vitro aortic arch-aortic nerve preparation was ...

journal_title：Journal of neurophysiology

authors： Munch PA

更新日期：1993-12-01 00:00:00

abstract：:To examine the mechanisms underlying milk-ejection bursts of oxytocin (OT) neurons during suckling, both in vivo and in vitro studies were performed on supraoptic OT neurons from lactating rats. The bursts were first recorded extracellularly in anesthetized rats. Burst-related electrical parameters were essentially th...

journal_title：Journal of neurophysiology

authors： Wang YF,Hatton GI

更新日期：2004-05-01 00:00:00

abstract：:The earliest neural response to a mechanical perturbation, the short-latency stretch response (R1: 20-45 ms), is known to exhibit "automatic gain-scaling" whereby its magnitude is proportional to preperturbation muscle activity. Because gain-scaling likely reflects an intrinsic property of the motoneuron pool (via the...

journal_title：Journal of neurophysiology

authors： Pruszynski JA,Kurtzer I,Lillicrap TP,Scott SH

更新日期：2009-08-01 00:00:00

abstract：:1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

journal_title：Journal of neurophysiology

authors： Blum KI,Idiart MA

更新日期：1994-09-01 00:00:00

abstract：:The ablation of afferent input results in the reorganization of sensory and motor cortices. In the primary visual cortex (V1), binocular retinal lesions deprive a corresponding cortical region [lesion projection zone (LPZ)] of visual input. Nevertheless, neurons in the LPZ regain responsiveness by shifting their recep...

journal_title：Journal of neurophysiology

authors： McManus JN,Ullman S,Gilbert CD

更新日期：2008-05-01 00:00:00

abstract：:1. The synthesis of information from different sensory modalities in the superior colliculus is an important precursor of attentive and orientation behavior. 2. This integration of multisensory information is critically dependent on inputs from a small area of association cortex, the anterior ectosylvian sulcus. Remov...

journal_title：Journal of neurophysiology

authors： Wallace MT,Stein BE

更新日期：1994-01-01 00:00:00

abstract：:We previously reported that neurons in the mediodorsal thalamic nucleus (MD) are topographically organized and express spatial and nonspatial coding properties similar to those of the prefrontal areas with which they are connected. In the course of mapping the dorsal thalamus, we also studied neurons in a subset of th...

journal_title：Journal of neurophysiology

authors： Tanibuchi I,Goldman-Rakic PS

更新日期：2005-01-01 00:00:00

abstract：:Various forms of synaptic plasticity, including spike timing-dependent plasticity, can be accounted for by calcium-dependent models of synaptic plasticity. However, recent results in which synaptic plasticity is induced by multi-spike protocols cannot simply be accounted for by linear superposition of plasticity due t...

journal_title：Journal of neurophysiology

authors： Cai Y,Gavornik JP,Cooper LN,Yeung LC,Shouval HZ

更新日期：2007-01-01 00:00:00

abstract：:The perforant path forms a monosynaptic connection between the cells of layer II of the entorhinal cortex and the pyramidal cells in hippocampal area CA3. Although this projection is prominent anatomically, very little is known about the physiological properties of this input. The distal location of these synapses sug...

journal_title：Journal of neurophysiology

authors： Urban NN,Henze DA,Barrionuevo G

更新日期：1998-09-01 00:00:00

abstract：:We compared the spatial sensitivity of neural responses in three areas of cat auditory cortex: primary auditory cortex (A1), the posterior auditory field (PAF), and the dorsal zone (DZ). Stimuli were 80-ms pure tones or broadband noise bursts varying in free-field azimuth (in the horizontal plane) or elevation (in the...

journal_title：Journal of neurophysiology

authors： Stecker GC,Harrington IA,Macpherson EA,Middlebrooks JC

更新日期：2005-08-01 00:00:00

abstract：:High-frequency burstlike electrical conditioning stimulation (HFS) applied to human skin induces an increase in mechanical pinprick sensitivity of the surrounding unconditioned skin (a phenomenon known as secondary hyperalgesia). The present study assessed the effect of frequency of conditioning stimulation on the dev...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Gousset S,Bouvy J,Stouffs A,Lebrun L,van Neerven SGA,Mouraux A

更新日期：2019-09-01 00:00:00

abstract：:Adaptation of movement may be driven by the difference between planned and actual motor performance, or the difference between expected and actual sensory consequences of movement. To identify how the nervous system differentially uses these signals, we asked: does motor adaptation occur when movement errors are irrel...

journal_title：Journal of neurophysiology

authors： Schaefer SY,Shelly IL,Thoroughman KA

更新日期：2012-02-01 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults and is often refractory to antiepileptic medications. The medial entorhinal area (MEA) is affected in TLE but mechanisms underlying hyperexcitability of MEA neurons require further elucidation. Previous studies suggest that inputs from the pres...

journal_title：Journal of neurophysiology

authors： Abbasi S,Kumar SS

更新日期：2015-11-01 00:00:00

abstract：:To investigate the specificity of fusimotor (gamma) drive during locomotion, gamma-efferents were recorded from the flexor digitorum longus (FDL) and flexor hallucis longus (FHL) nerves in a decerebrate cat preparation. These nerves innervate hindlimb muscles that differ in some aspects of their mechanical action. For...

journal_title：Journal of neurophysiology

authors： Murphy PR

更新日期：2002-01-01 00:00:00

abstract：:1. We examined the mean and standard deviation (SD) of interspike intervals (ISI) and the coefficient of variation (CV, the ratio of SD of ISI to mean ISI) of ISIs versus time to study discharge regularity of units in the dorsal cochlear nucleus (DCN) of decerebrate unanesthetized cats. The units were characterized by...

journal_title：Journal of neurophysiology

authors： Parham K,Kim DO

更新日期：1992-05-01 00:00:00

abstract：:Plasticity at the neuronal level commonly involves use-dependent changes in strength of particular synaptic pathways or regulation of postsynaptic properties by modulatory transmitters. Here we analyze a novel form of short-term plasticity mediated by use-dependent facilitation of postsynaptic responsiveness. Using cu...

journal_title：Journal of neurophysiology

authors： Svirskis G,Hounsgaard J

更新日期：1997-09-01 00:00:00

abstract：:Recent evidence has suggested that theta-frequency (4-7 Hz) oscillations around the human anterior cingulate cortex (ACC) and frontal cortex--that is, frontal midline theta (Fm theta) oscillations--may be involved in attentional processes in the brain. However, little is known about the physiological basis of Fm theta...

journal_title：Journal of neurophysiology

authors： Tsujimoto T,Shimazu H,Isomura Y

更新日期：2006-05-01 00:00:00

abstract：:In addition to a primary somatosensory cortex (SI), the cerebral cortex of all mammals contains a second somatosensory area (SII); however, the functions of SII are largely unknown. Our aim was to explore the functions of SII by comparing response properties of whisker-related neurons in this area with their counterpa...

journal_title：Journal of neurophysiology

authors： Kwegyir-Afful EE,Keller A

更新日期：2004-10-01 00:00:00

abstract：:1. The goal of this study was to compare the relative effectiveness of intrinsic inhibitory synaptic inputs in different layers of the cat motor cortex. Postsynaptic potentials (PSPs) were evoked in neurons located in the superficial (layer II-III) or deep layers (layer V) by local extracellular stimulation in vitro. ...

journal_title：Journal of neurophysiology

authors： van Brederode JF,Spain WJ

更新日期：1995-09-01 00:00:00

abstract：:Substance P (SP) is an undecapeptide that is co-localized with conventional transmitters in the nucleus accumbens (NAc). Its neurochemical and behavioral effects resemble those of cocaine and amphetamine. How SP accomplishes these effects is not known, partly because its cellular and synaptic effects are not well char...

journal_title：Journal of neurophysiology

authors： Kombian SB,Ananthalakshmi KV,Parvathy SS,Matowe WC

更新日期：2003-02-01 00:00:00

abstract：:The aim of this study was to determine the extent to which an attention-demanding visuomotor task affects the strength of the inhibitory control exerted by the wrist flexor group Ia afferents on the wrist extensor motoneurons. Effects of median nerve stimulation on the tonic activity of wrist extensor single motor uni...

journal_title：Journal of neurophysiology

authors： Nafati G,Schmied A,Rossi-Durand C

更新日期：2005-04-01 00:00:00

abstract：:1. The first experiment of this study determined the effects of low-frequency stimulation of the monkey superior colliculus on spontaneous saccades in the dark. Stimulation trains, subthreshold for eliciting short-latency fixed-vector saccades, were highly effective at biasing the metrics (direction and amplitude) of ...

journal_title：Journal of neurophysiology

authors： Glimcher PW,Sparks DL

更新日期：1993-03-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:The abilities of humans to discriminate the softness of rubber objects of differing compliance with a hand-held tool (a stylus) was measured under experimental conditions that differed as to how the tool was used and the kind of sensory information available. When the subject actively tapped or pressed the compliant o...

journal_title：Journal of neurophysiology

authors： LaMotte RH

更新日期：2000-04-01 00:00:00