Layer-specific modulation of entorhinal cortical excitability by presubiculum in a rat model of temporal lobe epilepsy.

abstract：:Multichannel techniques were used to assess the frequency specificity of activation in the central nucleus of the inferior colliculus (CIC) produced by electrical stimulation of localized regions within the ventral cochlear nucleus (VCN). Data were recorded in response to pure tones from 141 and 193 multiunit clusters...

journal_title：Journal of neurophysiology

authors： Shivdasani MN,Mauger SJ,Rathbone GD,Paolini AG

更新日期：2008-01-01 00:00:00

abstract：:1. We probed the gain and phase of the vestibuloocular reflex (VOR) during the execution of voluntary gaze saccades, with continuous oscillation or acceleration pulses, applied through a torque helmet. 2. Small-amplitude (< 1 degree), high-frequency (10-14 Hz) head oscillations in the horizontal or vertical plane were...

journal_title：Journal of neurophysiology

authors： Tabak S,Smeets JB,Collewijn H

更新日期：1996-11-01 00:00:00

abstract：:1. Intracellular recordings from CA1 pyramidal neurons in the rat hippocampal slice have been used to study synaptic transmission after maximal orthodromic stimulation of the Schaffer collateral-commissural fibers. Paired-pulse stimulation was used to investigate how the first (conditioning) stimulation influenced the...

journal_title：Journal of neurophysiology

authors： Nathan T,Lambert JD

更新日期：1991-11-01 00:00:00

abstract：:The creation of several prestin knockout and knockin mouse lines has demonstrated the importance of the intrinsic outer hair cell membrane protein prestin to mammalian hearing. However, the structure of prestin remains largely unknown, with even its major features in dispute. Several studies have suggested that presti...

journal_title：Journal of neurophysiology

authors： Currall B,Rossino D,Jensen-Smith H,Hallworth R

更新日期：2011-11-01 00:00:00

abstract：:The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...

journal_title：Journal of neurophysiology

authors： Cao J,Dorris DM,Meitzen J

更新日期：2018-10-01 00:00:00

abstract：:The functional coupling of neural circuits between the upper and lower limbs involving rhythmic movements is of interest to both motor control research and rehabilitation science. This coupling can be detected by examining the effect of remote rhythmic limb movement on the modulation of reflex amplitude in stationary ...

journal_title：Journal of neurophysiology

authors： Sasada S,Tazoe T,Nakajima T,Zehr EP,Komiyama T

更新日期：2010-07-01 00:00:00

abstract：:It has been shown that tetanic stimulation of area 2 of the somatosensory cortex produces long-term potentiation in neurons in area 4gamma, and this has been suggested as the basis of learning new motor skills. The purpose of this study was to further elucidate the characteristics of this projection by the use of evok...

journal_title：Journal of neurophysiology

authors： Caria MA,Kaneko T,Kimura A,Asanuma H

更新日期：1997-06-01 00:00:00

abstract：:Complex patterns of intercellular calcium signaling occur in the CA1 and CA2 regions of hippocampal slice organotypic cultures from neonatal mice. Spontaneous localized intercellular Ca2+ waves involving 5-15 cells propagate concentrically from multiple foci in the stratum oriens and s. radiatum. In these same regions...

journal_title：Journal of neurophysiology

authors： Harris-White ME,Zanotti SA,Frautschy SA,Charles AC

更新日期：1998-02-01 00:00:00

abstract：:We investigated whether heptanol and other long-chain alcohols that are known to block gap junctions interfere with the generation or the propagation of spreading depression (SD). Waves of SD were triggered by micro-injection of concentrated KCl solution in stratum (s.) radiatum of CA1 of rat hippocampal tissue slices...

journal_title：Journal of neurophysiology

authors： Largo C,Tombaugh GC,Aitken PG,Herreras O,Somjen GG

更新日期：1997-01-01 00:00:00

abstract：:1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...

journal_title：Journal of neurophysiology

authors： Golomb D,Wang XJ,Rinzel J

更新日期：1996-02-01 00:00:00

abstract：:Apical dendrites of layer 5 pyramidal cells in a slice preparation of rat sensorimotor cortex were depolarized focally by long-lasting glutamate iontophoresis while recording intracellularly from their soma. In most cells the firing pattern evoked by the smallest dendritic depolarization that evoked spikes consisted o...

journal_title：Journal of neurophysiology

authors： Schwindt P,Crill W

更新日期：1999-03-01 00:00:00

abstract：:1. Current- and voltage-clamp studies were conducted on isolated rat adrenal chromaffin cells to identify the voltage-dependent ion channels mediating inward currents. 2. Mean resting membrane potential of the isolated cells was -62 +/- 3 (SE) mV. Evoked action potentials were both Na+ and Ca2+ based, and whole cell v...

journal_title：Journal of neurophysiology

authors： Hollins B,Ikeda SR

更新日期：1996-08-01 00:00:00

abstract：:Recent work has investigated the link between motor learning and sensory function in arm movement control. A number of findings are consistent with the idea that motor learning is associated with systematic changes to proprioception (Haith A, Jackson C, Mial R, Vijayakumar S. Adv Neural Inf Process Syst 21: 593-600, 2...

journal_title：Journal of neurophysiology

authors： Wong JD,Kistemaker DA,Chin A,Gribble PL

更新日期：2012-12-01 00:00:00

abstract：:Many laboratories have reported the successful regeneration of neurons across damaged portions of the spinal cord. Associated improvements in hindlimb locomotor movements have been attributed to the formation of functional neuronal connections with the locomotor central pattern generator (CPG). However, regenerating a...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Kowalczewski J,Prochazka A

更新日期：2007-03-01 00:00:00

abstract：:Using microstimulation to imprint meaningful activity patterns into intrinsically highly interconnected neuronal substrates is hampered by activation of fibers of passage leading to a spatiotemporal "blur" of activity. The focus of the present study was to characterize the shape of this blur in the neocortex to arrive...

journal_title：Journal of neurophysiology

authors： Butovas S,Schwarz C

更新日期：2003-11-01 00:00:00

abstract：:Olfactory receptor neurons (ORNs) respond to odorants with changes in the action potential firing rate. Excitatory responses, consisting of firing increases, are mediated by a cyclic AMP cascade that leads to the activation of cationic nonselective cyclic nucleotide-gated (CNG) channels and Ca2+-dependent Cl- (ClCa) c...

journal_title：Journal of neurophysiology

authors： Delgado R,Saavedra MV,Schmachtenberg O,Sierralta J,Bacigalupo J

更新日期：2003-09-01 00:00:00

abstract：:Although fluorescence microscopy has proven to be one of the most powerful tools in biology, its application to the intact animal has been limited to imaging several hundred micrometers below the surface. The rest of the animal has eluded investigation at the microscopic level without excising tissue or performing ext...

journal_title：Journal of neurophysiology

authors： Levene MJ,Dombeck DA,Kasischke KA,Molloy RP,Webb WW

更新日期：2004-04-01 00:00:00

abstract：:Using intrinsic signal optical imaging (ISI), we have shown previously that the point spread of evoked activity in the rat barrel cortex in response to single-whisker stimulation encompasses a surprisingly large area. Given that our typical stimulation consists of five deflections at 5 Hz, the large area of evoked act...

journal_title：Journal of neurophysiology

authors： Polley DB,Chen-Bee CH,Frostig RD

更新日期：1999-02-01 00:00:00

abstract：:1. The preceding study described a corrective response in cats when one hind leg steps into a hole. In this investigation we examine the extent to which this behavior is organized at the spinal level by comparing the responses elicited in intact and chronic spinal cats. 2. Adult cats were trained to step bipedally wit...

journal_title：Journal of neurophysiology

authors： Hiebert GW,Gorassini MA,Jiang W,Prochazka A,Pearson KG

更新日期：1994-02-01 00:00:00

abstract：:In human spinal cord injury (SCI), imposed unilateral hip movements trigger multijoint, coordinated reflexes that might incorporate interneuronal circuitry involved in normal motor control, such as neural pathways associated with the reflex control of locomotion. To further investigate the complexity of these hip-trig...

journal_title：Journal of neurophysiology

authors： Onushko T,Schmit BD

更新日期：2007-10-01 00:00:00

abstract：:1. gamma-Aminobutyric acid (GABA) withdrawal syndrome (GWS) represents a particular model of focal epilepsy consecutive to the interruption of a chronic intracortical GABA infusion and is characterized by the appearance of focal epileptic electroencephalographic (EEG) discharges and localized clinical signs on withdra...

journal_title：Journal of neurophysiology

authors： Silva-Barrat C,Araneda S,Menini C,Champagnat J,Naquet R

更新日期：1992-03-01 00:00:00

abstract：:Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from isolated animal retina are commonly used to inform the design of these implants. However, such electrical recordings provide limited info...

journal_title：Journal of neurophysiology

authors： Weitz AC,Behrend MR,Lee NS,Klein RL,Chiodo VA,Hauswirth WW,Humayun MS,Weiland JD,Chow RH

更新日期：2013-04-01 00:00:00

abstract：:The short-term (3-51 days) and long-term (31-42 wk) effects of corpus callosum transection on the receptive-field properties of neurons were assessed at the single-cell, architectural, and topographical levels of organization in the cat striate cortex. Corpus callosum transection decreased the proportion of neurons th...

journal_title：Journal of neurophysiology

authors： Payne BR,Pearson HE,Berman N

更新日期：1984-09-01 00:00:00

abstract：:Using near-infrared spectroscopy (NIRS) and multichannel probes, we studied hemoglobin (Hb) concentration changes when single-pulse transcranial magnetic stimulation (TMS) was applied over the left hemisphere primary motor cortex (M1). Seventeen measurement probes were centered over left M1. Subjects were studied in b...

journal_title：Journal of neurophysiology

authors： Furubayashi T,Mochizuki H,Terao Y,Arai N,Hanajima R,Hamada M,Matsumoto H,Nakatani-Enomoto S,Okabe S,Yugeta A,Inomata-Terada S,Ugawa Y

更新日期：2013-03-01 00:00:00

abstract：:The earliest neural response to a mechanical perturbation, the short-latency stretch response (R1: 20-45 ms), is known to exhibit "automatic gain-scaling" whereby its magnitude is proportional to preperturbation muscle activity. Because gain-scaling likely reflects an intrinsic property of the motoneuron pool (via the...

journal_title：Journal of neurophysiology

authors： Pruszynski JA,Kurtzer I,Lillicrap TP,Scott SH

更新日期：2009-08-01 00:00:00

abstract：:In reaching to grasp an object, the arm transports the hand to the intended location as the hand shapes to grasp the object. Prior studies that tracked arm endpoint and grip aperture have shown that reaching and grasping, while proceeding in parallel, are interdependent to some degree. Other studies of reaching and gr...

journal_title：Journal of neurophysiology

authors： Rouse AG,Schieber MH

更新日期：2015-12-01 00:00:00

abstract：:Discrete anatomic structures in the monkey somatic sensory thalamus may segregate input arising from different peripheral receptors and from different parts of the body. It has been proposed that these structures serve as components of modality- and place-specific pathways from the periphery to the cortex. We now test...

journal_title：Journal of neurophysiology

authors： Patel S,Ohara S,Dougherty PM,Gracely RH,Lenz FA

更新日期：2006-02-01 00:00:00

abstract：:The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...

journal_title：Journal of neurophysiology

authors： Kuroki S,Watanabe J,Nishida S

更新日期：2016-03-01 00:00:00

abstract：:Impulse from soleus muscle afferents were recorded in premammillary cats that were walking on a treadmill. In normal walking the effects of gamma-motoneurons on impulse rates of muscle spindle afferents are confounded by the effects of the large length changes that occur. To isolate the effects of gamma-motoneurons th...

journal_title：Journal of neurophysiology

authors： Taylor J,Stein RB,Murphy PR

更新日期：1985-02-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00