Depolarization-induced facilitation of a plateau-generating current in ventral horn neurons in the turtle spinal cord.

abstract：:The ventromedial medulla is implicated in a variety of functions including nociceptive and cardiovascular modulation and the control of thermoregulation. To determine whether single microinjections into the ventromedial medulla elicit changes in one or multiple functional systems, the GABA(A) receptor antagonist bicuc...

journal_title：Journal of neurophysiology

authors： Nason MW Jr,Mason P

更新日期：2004-07-01 00:00:00

abstract：:We are studying the functional "logic" of neuromodulatory actions in a simple central pattern generator (CPG)-effector system, the heart of the blue crab Callinectes sapidus. The rhythmic contractions of this heart are neurogenic, driven by rhythmic motor patterns generated by the cardiac ganglion (CG). Here we used a...

journal_title：Journal of neurophysiology

authors： Fort TJ,Brezina V,Miller MW

更新日期：2007-11-01 00:00:00

abstract：:1. Spike rates of cells in the cat's lateral superior olive (LSO) depend on interaural level differences (ILDs) and envelope interaural time differences (ITDs) of amplitude-modulated tones presented to both ears. We previously proposed that these sensitivities arise from a common mechanism, which is the IE binaural in...

journal_title：Journal of neurophysiology

authors： Joris PX

更新日期：1996-10-01 00:00:00

abstract：:Substance P (SP) hyperpolarizes approximately 80% of ferret vagal sensory neurons (nodose ganglion neurons) via NK-1 receptor-mediated activation of a potassium current (IK). A depolarizing current activated by membrane hyperpolarization could minimize the SP-induced hyperpolarization. Such a current exists in 65% of ...

journal_title：Journal of neurophysiology

authors： Jafri MS,Weinreich D

更新日期：1998-02-01 00:00:00

abstract：:Recent work has implicated low-frequency (<20 Hz) neuronal phase information as important for both auditory (<10 Hz) and speech [theta (∼4-8 Hz)] perception. Activity on the timescale of theta corresponds linguistically to the average length of a syllable, suggesting that information within this range has consequences...

journal_title：Journal of neurophysiology

authors： Cogan GB,Poeppel D

更新日期：2011-08-01 00:00:00

abstract：:Changes in temperature of up to several degrees have been reported in different brain regions during various behaviors or in response to environmental stimuli. We investigated temperature sensitivity of dopaminergic neurons of the rat substantia nigra pars compacta (SNc), an area important for motor and emotional cont...

journal_title：Journal of neurophysiology

authors： Guatteo E,Chung KK,Bowala TK,Bernardi G,Mercuri NB,Lipski J

更新日期：2005-11-01 00:00:00

abstract：:1. The discharge patterns of 359 single neurons in the hand representation of primary somatosensory cortex (SI) of two monkeys (Macaca mulatta) were recorded during the performance of a passive texture discrimination task with the contralateral hand (104 in area 3b, 149 in area 1, and 106 in area 2). Three nyloprint s...

journal_title：Journal of neurophysiology

authors： Tremblay F,Ageranioti-Bélanger SA,Chapman CE

更新日期：1996-11-01 00:00:00

abstract：:1. We investigated the glycine-induced response in ventromedial hypothalamic (VMH) neurons freshly dissociated from 8- to 12-day-old rats using the nystatin and gramicidin perforated patch recording modes. The nystatin-formed pores in the plasma membrane are permeable for both monovalent cations and anions, whereas th...

journal_title：Journal of neurophysiology

authors： Abe Y,Furukawa K,Itoyama Y,Akaike N

更新日期：1994-10-01 00:00:00

abstract：:1. Membrane currents of normal and TEA-injected cat lumbar motoneurons were investigated using the technique of somatic voltage clamp. 2. The current-voltage (I-V) relation of healthy motoneurons contains a region of negative slope conductance caused by a persistent inward current component (Ii). In the most striking ...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1980-06-01 00:00:00

abstract：:1. Properties of 90 lateral cervical nucleus (LCN) neurons responsive to light tactile stimulation of ipsilateral body surfaces were examined in pentobarbital sodium-anesthetized raccoons. Peripheral receptive fields (RFs) of 60 of these lay totally or partially on glabrous skin of the forepaw. There were 71 neurons a...

journal_title：Journal of neurophysiology

authors： Simone DA,Pubols BH Jr

更新日期：1991-06-01 00:00:00

abstract：:1. The neurophysiological basis for the sensation of prickle evoked by contact of some fabrics with the skin is reported. 2. Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle. These recordings showed that all low-threshold mec...

journal_title：Journal of neurophysiology

authors： Garnsworthy RK,Gully RL,Kenins P,Mayfield RJ,Westerman RA

更新日期：1988-04-01 00:00:00

abstract：:1. The purpose of this study is to define the cortical regions that subserve voluntary saccadic eye movements and spatial working memory in humans. 2. Regional cerebral blood flow (rCBF) during performance of oculomotor tasks was measured with [15O]-H2O positron emission tomography (PET). Eleven well-trained, healthy ...

journal_title：Journal of neurophysiology

authors： Sweeney JA,Mintun MA,Kwee S,Wiseman MB,Brown DL,Rosenberg DR,Carl JR

更新日期：1996-01-01 00:00:00

abstract：:The Wilson-Cowan population model of neural activity has greatly influenced our understanding of the mechanisms for the generation of brain rhythms and the emergence of structured brain activity. As well as the many insights that have been obtained from its mathematical analysis, it is now widely used in the computati...

journal_title：Journal of neurophysiology

authors： Byrne Á,O'Dea RD,Forrester M,Ross J,Coombes S

更新日期：2020-02-01 00:00:00

abstract：:Neurons in area MT, a motion-sensitive area of extrastriate cortex, respond to a step of target velocity with a transient-sustained firing pattern. The transition from a high initial firing rate to a lower sustained rate occurs over a time course of 20-80 ms and is considered a form of short-term adaptation. The prese...

journal_title：Journal of neurophysiology

authors： Priebe NJ,Churchland MM,Lisberger SG

更新日期：2002-07-01 00:00:00

abstract：:The timing of brief stationary sounds has been shown to alter the perceived speed of visual apparent motion (AM), presumably by altering the perceived timing of the individual frames of the AM stimuli and/or the duration of the interstimulus intervals (ISIs) between those frames. To investigate the neural correlates o...

journal_title：Journal of neurophysiology

authors： Kafaligonul H,Albright TD,Stoner GR

更新日期：2018-09-01 00:00:00

abstract：:The exercise pressor reflex, a crucial component of the cardiovascular response under physiological and pathophysiological states, is activated via metabolic and mechanical mediators that originate from contracting muscles and stimulate group III and IV afferents. We reported previously that stimulation of mu opioid r...

journal_title：Journal of neurophysiology

authors： Hassan B,Kim JS,Farrag M,Kaufman MP,Ruiz-Velasco V

更新日期：2014-12-15 00:00:00

abstract：:1. Receptive fields (RFs) of neurons in the primary somatosensory (SI) cortex were defined before, during, and after electrical stimulation of myelinated fibers in the dorsal cutaneous branch of the ulnar nerve in adult pentobarbital sodium-anesthetized cats. 2. This stimulation resulted in an approximately threefold ...

journal_title：Journal of neurophysiology

authors： Recanzone GH,Allard TT,Jenkins WM,Merzenich MM

更新日期：1990-05-01 00:00:00

abstract：:1. To test whether the cerebellum is involved in compensating for orbital nonlinearities, we recorded discharges of saccadic burst neurons in the fastigial oculomotor region (FOR) during both centrifugal and centripetal saccades in two trained macaque monkeys. 2. We also investigated the metrics of centrifugal and cen...

journal_title：Journal of neurophysiology

authors： Ohtsuka K,Sato H,Noda H

更新日期：1994-05-01 00:00:00

abstract：:1. Monkeys with large unilateral surgical ablations of striate cortex, sustained either in adulthood or at 5-6 wk of age, were trained on an oculomotor detection and localization task and tested with visual stimuli in the hemifields ipsilateral and contralateral to the lesion 2-5 yr after surgery. 2. Monkeys with lesi...

journal_title：Journal of neurophysiology

authors： Moore T,Rodman HR,Repp AB,Gross CG,Mezrich RS

更新日期：1996-12-01 00:00:00

abstract：:This study determined the effect of mixed (slip- and trip-like stance perturbation) training on reactive responses in people with chronic stroke (PwCS) and examined modulation of their reactive responses on higher intensity perturbations posttraining (scaling). Twelve PwCS were exposed to consecutive blocks of treadmi...

journal_title：Journal of neurophysiology

authors： Dusane S,Bhatt T

更新日期：2020-07-01 00:00:00

abstract：:The mechanical state encoded by slowly adapting type 1 mechanoreceptors (SAI) during indentation was examined using an isolated preparation in a rat model. Skin and its intact innervation were harvested from the medial thigh of the rat hindlimb and placed in a dish, with the corium side down, containing synthetic inte...

journal_title：Journal of neurophysiology

authors： Ge W,Khalsa PS

更新日期：2002-04-01 00:00:00

abstract：:1. We have stimulated responses of stellate cells in the anteroventral cochlear nucleus (AVCN) to single-formant stimuli (SFSs) with the use of recorded auditory-nerve fiber (ANF) responses as inputs. In particular, two important features of temporal discharge patterns, the phase locking to best frequency (BF) tones a...

journal_title：Journal of neurophysiology

authors： Wang X,Sachs MB

更新日期：1995-04-01 00:00:00

abstract：:Spatiotemporal patterns of dorsal root-evoked potentials were studied in transverse slices of the rat spinal cord by monitoring optical signals from a voltage-sensitive dye with multiple-photodiode optic camera. Typically, dorsal root stimulation generated two basic waveforms of voltage images: dual-component images c...

journal_title：Journal of neurophysiology

authors： Ziskind-Conhaim L,Redman S

更新日期：2005-09-01 00:00:00

abstract：:Pentobarbital, a general anesthetic, has received extensive study for its ability to potentiate inhibition at GABA(A) subtype of receptors for GABA. Using whole cell current-clamp techniques and bath applications, we determined the effects of pentobarbital and GABA receptor antagonists on the membrane properties and t...

journal_title：Journal of neurophysiology

authors： Wan X,Puil E

更新日期：2002-12-01 00:00:00

abstract：:Biological gain mechanisms regulate the sensitivity and dynamics of signaling pathways at the systemic, cellular, and molecular levels. In the sympathetic nervous system, gain in sensory-motor feedback loops is essential for homeostatic regulation of blood pressure and body temperature. This study shows how synaptic c...

journal_title：Journal of neurophysiology

authors： Wheeler DW,Kullmann PH,Horn JP

更新日期：2004-11-01 00:00:00

abstract：:Magnocellular red nucleus (RNm) is involved in controlling goal-directed limb movements such as reaching to grasp. We tested two hypotheses related to RNm's role in controlling reach-to-grasp movements. One hypothesis is that forelimb RNm neurons are grasp specific, and the other is that they specify the timing of met...

journal_title：Journal of neurophysiology

authors： Van Kan PL,McCurdy ML

更新日期：2002-03-01 00:00:00

abstract：:The purpose of this study was to examine which primary afferent fibers are sensitized to mechanical stimuli after an experimental surgical incision to the glabrous skin of the rat hindpaw. Afferent fibers teased from the L(5) dorsal root or the tibial nerve were recorded in anesthetized rats. The mechanical response p...

journal_title：Journal of neurophysiology

authors： Hämäläinen MM,Gebhart GF,Brennan TJ

更新日期：2002-02-01 00:00:00

abstract：:An initial overload of intracellular Ca2+ plays a critical role in the delayed death of hippocampal CA1 neurons that die a few days after transient ischemia. Without direct evidence, the prevailing hypothesis has been that Ca2+ overload may recur until cell death. Here, we report the first measurements of intracellula...

journal_title：Journal of neurophysiology

authors： Connor JA,Razani-Boroujerdi S,Greenwood AC,Cormier RJ,Petrozzino JJ,Lin RC

更新日期：1999-01-01 00:00:00

abstract：:The horizontal cell is a second-order retinal neuron that is depolarized in the dark and responds to light with graded potential changes. In such a nonspiking neuron, not only the voltage-gated ionic conductances but also Ca(2+) regulation mechanisms, e.g., the Na(+)/Ca(2+) exchange and the Ca(2+) pump, are considered...

journal_title：Journal of neurophysiology

authors： Hayashida Y,Yagi T

更新日期：2002-01-01 00:00:00

abstract：:1. Buffering of glutamate-induced Ca2+ loads in single rat hippocampal neurons grown in primary culture was studied with ratiometric fluorescent Ca2+ indicators. The hypothesis that mitochondria buffer the large Ca2+ loads elicited by glutamate was tested. 2. The relationship between glutamate concentration and the re...

journal_title：Journal of neurophysiology

authors： Wang GJ,Thayer SA

更新日期：1996-09-01 00:00:00