Identification of the physical stimulus and the neural basis of fabric-evoked prickle.

abstract：:The GABA withdrawal syndrome (GWS) is a model of local status epilepticus consecutive to the interruption of a prolonged GABA infusion into the rat somatomotor cortex. Bursting patterns in slices from GWS rats include intrinsic bursts of action potentials (APs) induced by intracellular depolarizing current injection a...

journal_title：Journal of neurophysiology

authors： Silva-Barrat C,Szente M,Menini C,Velluti JC,Champagnat J

更新日期：2001-05-01 00:00:00

abstract：:In this study we analyzed transient voltage-activated K+ currents (IA) of projection neurons and local interneurons in the antennal lobe of the cockroach Periplaneta americana The antennal lobe is the first synaptic processing station for olfactory information in insects. Local interneurons are crucial for computing o...

journal_title：Journal of neurophysiology

authors： Paeger L,Bardos V,Kloppenburg P

更新日期：2017-05-01 00:00:00

abstract：:It remains unclear how attention affects the tuning of individual neurons in visual cerebral cortex. Some observations suggest that attention preferentially enhances responses to low contrast stimuli, whereas others suggest that attention proportionally affects responses to all stimuli. Resolving how attention affects...

journal_title：Journal of neurophysiology

authors： Lee J,Maunsell JH

更新日期：2010-08-01 00:00:00

abstract：:Whole cell voltage-clamp recordings from acutely isolated hippocampal CA1 pyramidal cells from adult guinea pigs were used to evaluate divalent cations as possible blockers of the postexposure current (Ipe). Ipe is a cation current that is triggered by the rise in intracellular Ca2+ concentration that occurs after the...

journal_title：Journal of neurophysiology

authors： Chen QX,Perkins KL,Wong RK

更新日期：1998-02-01 00:00:00

abstract：:Although it is generally accepted that humans cannot perceive sounds in the frequency range above 20 kHz, the question of whether the existence of such "inaudible" high-frequency components may affect the acoustic perception of audible sounds remains unanswered. In this study, we used noninvasive physiological measure...

journal_title：Journal of neurophysiology

authors： Oohashi T,Nishina E,Honda M,Yonekura Y,Fuwamoto Y,Kawai N,Maekawa T,Nakamura S,Fukuyama H,Shibasaki H

更新日期：2000-06-01 00:00:00

abstract：:The responsiveness of sensory neurons to muscle metabolites is altered under the conditions of insufficient limb blood supply in some diseases, such as peripheral artery disease. The purpose of this study was to examine ATP-induced current with activation of purinergic P2X subtypes P2X₃ and P2X₂/₃ in dorsal root gangl...

journal_title：Journal of neurophysiology

authors： Xing J,Lu J,Li J

更新日期：2013-04-01 00:00:00

abstract：:A desirable goal of functional MRI (fMRI), both clinically and for basic research, is to produce detailed maps of cortical function in individual subjects. Single-subject mapping of the somatotopic hand representation in the human primary somatosensory cortex (S1) has been performed using both phase-encoding and block...

journal_title：Journal of neurophysiology

authors： Besle J,Sánchez-Panchuelo RM,Bowtell R,Francis S,Schluppeck D

更新日期：2013-05-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:The objectives of this study were to probe the contribution of spinal neuron persistent sodium conductances to reflex hyperexcitability in human chronic spinal cord injury. The intrinsic excitability of spinal neurons provides a novel target for medical intervention. Studies in animal models have shown that persistent...

journal_title：Journal of neurophysiology

authors： Theiss RD,Hornby TG,Rymer WZ,Schmit BD

更新日期：2011-06-01 00:00:00

abstract：:The reward value of a stimulus can be learned through two distinct mechanisms: reinforcement learning through repeated stimulus-reward pairings and abstract inference based on knowledge of the task at hand. The reinforcement mechanism is often identified with midbrain dopamine neurons. Here we show that a neural pathw...

journal_title：Journal of neurophysiology

authors： Bromberg-Martin ES,Matsumoto M,Hong S,Hikosaka O

更新日期：2010-08-01 00:00:00

abstract：:The rhythmic delivery of visual stimuli evokes large-scale neuronal entrainment in the form of steady-state oscillatory field potentials. The spatiotemporal properties of stimulus drive appear to constrain the relative degrees of neuronal entrainment. Specific frequency ranges, for example, are uniquely suited for enh...

journal_title：Journal of neurophysiology

authors： Nguyen T,Kuntzelman K,Miskovic V

更新日期：2017-07-01 00:00:00

abstract：:1. The electrical responses of nociceptive (N) lateral and N medial neurons of the leech segmental ganglion to mechanical, chemical, and thermal stimulation of the skin were studied in a superfused ganglion-body wall preparation. 2. Mechanical indentation of the skin > 10 mN evoked in both types of cells a sustained d...

journal_title：Journal of neurophysiology

authors： Pastor J,Soria B,Belmonte C

更新日期：1996-06-01 00:00:00

abstract：:It is controversial whether simple-spike activity of cerebellar Purkinje cells during arm movements encodes movement kinematics like velocity or dynamics like muscle activities. To examine this issue, we trained monkeys to flex or extend the elbow by 45 degrees in 400 ms under resistive and assistive force fields but ...

journal_title：Journal of neurophysiology

authors： Yamamoto K,Kawato M,Kotosaka S,Kitazawa S

更新日期：2007-02-01 00:00:00

abstract：:Recent evidence suggests that changes in sodium channel expression and localization may be involved in some pathological pain syndromes. SNS, a tetrodotoxin-resistant (TTX-R) sodium channel, is preferentially expressed in small dorsal root ganglion (DRG) neurons, many of which are nociceptive. TTX-R sodium currents an...

journal_title：Journal of neurophysiology

authors： Fjell J,Cummins TR,Fried K,Black JA,Waxman SG

更新日期：1999-02-01 00:00:00

abstract：:In common with other sensory cortices, the mammalian primary auditory cortex (AI) demonstrates the capacity for large-scale reorganization following many experimental situations. For example, training animals in frequency-discrimination tasks has been shown to result in an increase in cortical frequency representation...

journal_title：Journal of neurophysiology

authors： Talwar SK,Gerstein GL

更新日期：2001-10-01 00:00:00

abstract：:In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...

journal_title：Journal of neurophysiology

authors： Erdemli G,Xu YZ,Krnjević K

更新日期：1998-11-01 00:00:00

abstract：:Behavioral studies have shown that object recognition becomes severely impaired at fast presentation rates, indicating a limitation in temporal processing capacity. Here, we studied whether this behavioral limit in object recognition reflects limitations in the temporal processing capacity of early visual areas tuned ...

journal_title：Journal of neurophysiology

authors： McKeeff TJ,Remus DA,Tong F

更新日期：2007-07-01 00:00:00

abstract：:1. The medullary reticular formation (MRF) is known to be involved in the modulation of certain reproductive behaviors. Ejaculation in the male, disrupted after spinal transection, may depend on a spinal-bulbo-spinal connection. To determine whether single neurons in the MRF receive sensory input from the male genital...

journal_title：Journal of neurophysiology

authors： Hubscher CH,Johnson RD

更新日期：1996-10-01 00:00:00

abstract：:We investigated object representation in area TE, the anterior part of monkey inferotemporal (IT) cortex, with a combination of optical and extracellular recordings in anesthetized monkeys. We found neurons that respond to visual stimuli composed of naturally distinguishable parts. These neurons were sensitive to a pa...

journal_title：Journal of neurophysiology

authors： Yamane Y,Tsunoda K,Matsumoto M,Phillips AN,Tanifuji M

更新日期：2006-12-01 00:00:00

abstract：:The ionic mechanisms underlying the termination of action-potential (AP) bursts and postburst afterhyperpolarization (AHP) in intrinsically bursting (IB) neocortical neurons were investigated by performing intracellular recordings in thin slices of rat sensorimotor cortex. The blockade of Ca(2+)-activated K(+) current...

journal_title：Journal of neurophysiology

authors： Franceschetti S,Lavazza T,Curia G,Aracri P,Panzica F,Sancini G,Avanzini G,Magistretti J

更新日期：2003-04-01 00:00:00

abstract：:1. In a search for correlated fast rhythms in recurrent laryngeal (RL) expiratory (E) activities, we performed spectral and coherence analysis on bilateral RL nerve discharges in 54 midcollicular decerebrate, paralyzed cats. 2. Inspiratory (I) RL activities showed in almost all cases high-frequency oscillations (HFO, ...

journal_title：Journal of neurophysiology

authors： Huang WX,Christakos CN,Cohen MI,He Q

更新日期：1993-11-01 00:00:00

abstract：:Precise motion control is critical to human survival on Earth and in space. Motion sensation is inherently imprecise, and the functional implications of this imprecision are not well understood. We studied a "vestibular" manual control task in which subjects attempted to keep themselves upright with a rotational hand ...

journal_title：Journal of neurophysiology

authors： Rosenberg MJ,Galvan-Garza RC,Clark TK,Sherwood DP,Young LR,Karmali F

更新日期：2018-12-01 00:00:00

abstract：:The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...

journal_title：Journal of neurophysiology

authors： Cao J,Dorris DM,Meitzen J

更新日期：2018-10-01 00:00:00

abstract：:We investigated the topography of human cortical activation during an antisaccade task by focal transcranial magnetic stimulation (TMS). We used a figure-eight shaped coil, with the stimulus intensity set just above the threshold for activation of the hand motor areas but weak enough not to elicit blinks. TMS was deli...

journal_title：Journal of neurophysiology

authors： Terao Y,Fukuda H,Ugawa Y,Hikosaka O,Hanajima R,Furubayashi T,Sakai K,Miyauchi S,Sasaki Y,Kanazawa I

更新日期：1998-08-01 00:00:00

abstract：:The essential role of calcium in the induction of long-term potentiation (LTP) has been well established. In particular, calcium influx via the N-methyl-D-aspartate (NMDA) receptor (NMDAR) is important for LTP induction in many pathways. However, the specific roles of other calcium sources in hippocampal LTP are less ...

journal_title：Journal of neurophysiology

authors： Raymond CR,Redman SJ

更新日期：2002-07-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:Two of the biggest health problems facing us today are addiction to nicotine and the increased prevalence of obesity. Interestingly, nicotine attenuates obesity, but the underlying mechanism is not clear. Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomel...

journal_title：Journal of neurophysiology

authors： Huang H,Xu Y,van den Pol AN

更新日期：2011-09-01 00:00:00

abstract：:Animals and human beings sense and react to real/potential dangerous stimuli. However, the supraspinal mechanisms relating noxious sensing and nocifensive behavior are mostly unknown. The collateralization and spatial organization of interrelated neurons are important determinants of coordinated network function. Here...

journal_title：Journal of neurophysiology

authors： Leiras R,Martín-Cora F,Velo P,Liste T,Canedo A

更新日期：2016-01-01 00:00:00

abstract：:1. We used period/amplitude (PA) analysis to survey electroencephalography (EEG) across vigilance states in the Sprague-Dawley rat. We found a fast cortical EEG frequency band, which we designate rho, whose wave amplitude in rapid eye movement (REM) was elevated above the levels in both waking and nonrapid eye movemen...

journal_title：Journal of neurophysiology

authors： Campbell IG,Feinberg I

更新日期：1993-04-01 00:00:00

abstract：:Previous behavioral work has shown the existence of both anticipatory and reactive grip force responses to predictable load perturbations, but how the brain implements anticipatory control remains unclear. Here we recorded electroencephalographs while participants were subjected to predictable and unpredictable extern...

journal_title：Journal of neurophysiology

authors： Kourtis D,Kwok HF,Roach N,Wing AM,Praamstra P

更新日期：2008-02-01 00:00:00