Maintaining grip: anticipatory and reactive EEG responses to load perturbations.

abstract：:The R6/2 mouse is the most frequently used model for experimental and preclinical drug trials in Huntington's disease (HD). When the R6/2 mouse was first developed, it carried exon 1 of the huntingtin gene with ~150 cytosine-adenine-guanine (CAG) repeats. The model presented with a rapid and aggressive phenotype that ...

journal_title：Journal of neurophysiology

authors： Cummings DM,Alaghband Y,Hickey MA,Joshi PR,Hong SC,Zhu C,Ando TK,André VM,Cepeda C,Watson JB,Levine MS

更新日期：2012-01-01 00:00:00

abstract：:The role of the nitric oxide (NO)-cGMP signaling cascade in modulation of peripheral nociception is controversial. Although behavioral studies have suggested both pro- and anti-nociceptive effects, little is known about the direct action of this signaling cascade on primary afferent nociceptive neurons that mediate th...

journal_title：Journal of neurophysiology

authors： Levy D,Strassman AM

更新日期：2004-08-01 00:00:00

abstract：:The nucleus of the solitary tract (NST) and the parabrachial nuclei (PbN) are the first and second relays in the rodent central taste pathway. A series of electrophysiological experiments revealed that spontaneous and taste-evoked activities of brain stem gustatory neurons are altered by descending input from multiple...

journal_title：Journal of neurophysiology

authors： Li CS,Lu DP,Cho YK

更新日期：2015-06-01 00:00:00

abstract：:Studies on the expression and cellular function of sigma receptors in autonomic neurons were conducted in neonatal rat intracardiac and superior cervical (SCG) ganglia. Individual neurons from SCG and intracardiac ganglia were shown to express transcripts encoding the sigma-1 receptor using single-cell RT-PCR techniqu...

journal_title：Journal of neurophysiology

authors： Zhang H,Cuevas J

更新日期：2002-06-01 00:00:00

abstract：:Targeting the melanin-concentrating hormone (MCH) system has been suggested as a potential treatment for obesity, anxiety disorders, as well as addiction. Despite the therapeutic potential of MCH agonists and antagonists, the endogenous factors regulating MCH activity, in particular those implicated in anxiety and rew...

journal_title：Journal of neurophysiology

authors： Parsons MP,Hirasawa M

更新日期：2011-03-01 00:00:00

abstract：:We recently reported evidence indicating that selective attention is deployed to a target location in a multi-object display, when the target event (a change of one of the objects) is preceded by subliminal flicker in the gamma range. However, concerns have been raised regarding the stimuli used in this study and the ...

journal_title：Journal of neurophysiology

authors： Cheadle SW,Parton A,Müller HJ,Usher M

更新日期：2011-02-01 00:00:00

abstract：:1. The synthesis of information from different sensory modalities in the superior colliculus is an important precursor of attentive and orientation behavior. 2. This integration of multisensory information is critically dependent on inputs from a small area of association cortex, the anterior ectosylvian sulcus. Remov...

journal_title：Journal of neurophysiology

authors： Wallace MT,Stein BE

更新日期：1994-01-01 00:00:00

abstract：:Motor behavior often occurs in environments with multiple goal options that can vary during the ongoing action. We explored this situation by requiring subjects to select between different target options during an ongoing reach. During split trials the original target was replaced with a left and a right flanking targ...

journal_title：Journal of neurophysiology

authors： Kurtzer IL,Muraoka T,Singh T,Prasad M,Chauhan R,Adhami E

更新日期：2020-10-01 00:00:00

abstract：:A major goal of neuroscience is to understand the functions of networks of neurons in cognition and behavior. Recent work has focused on implanting arrays of ∼100 immovable electrodes or smaller numbers of individually adjustable electrodes, designed to target a few cortical areas. We have developed a recording system...

journal_title：Journal of neurophysiology

authors： Feingold J,Desrochers TM,Fujii N,Harlan R,Tierney PL,Shimazu H,Amemori K,Graybiel AM

更新日期：2012-04-01 00:00:00

abstract：:Brief movements of a large-field visual stimulus elicit short-latency tracking eye movements termed "ocular following responses" (OFRs). To address the question of whether OFRs can be elicited by purely binocular motion signals in the absence of monocular motion cues, we measured OFRs from monkeys using dichoptic moti...

journal_title：Journal of neurophysiology

authors： Hayashi R,Miura K,Tabata H,Kawano K

更新日期：2008-05-01 00:00:00

abstract：:Recent experimental findings suggest that there may be rich physiological information embedded within the power spectrum of neurophysiological recordings, which, in addition to power in specific oscillatory frequencies, can be extracted with the appropriate model. This article reviews previous empirical and modeling r...

journal_title：Journal of neurophysiology

authors： Gao R

更新日期：2016-02-01 00:00:00

abstract：:Exposure to odorants results in a rapid (<10 s) reduction in odor-evoked activity in the rat piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To further understand this form of cortical plasticity, a detailed analysis of its odor specificity was performed. Habituation of o...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-01-01 00:00:00

abstract：:1. R2 and LPl1 are homologous giant cholinergic neurons in the nervous system of Aplysia with overlapping and almost symmetrical axonal trees extending over most of the body wall. In spite of much experimental study, the behavioral role of the cells has remained unknown. 2. After intrasomatic injection of R2 and LPl1 ...

journal_title：Journal of neurophysiology

authors： Rayport SG,Ambron RT,Babiarz J

更新日期：1983-04-01 00:00:00

abstract：:1. To obtain a comprehensive map of the ascending projection of the midbrain periaqueductal gray, small amounts of [3H]leucine were injected into discrete regions of the periaqueductal gray (PAG) of the monkey. 2. Despite the fact that different regions of the PAG were injected in separate animals, the majority of the...

journal_title：Journal of neurophysiology

authors： Mantyh PW

更新日期：1983-03-01 00:00:00

abstract：:During auditory stimulation with several frequency components, distortion products (DPs) are generated as byproduct of nonlinear cochlear amplification. After generated, DP energy is reemitted into the ear channel where it can be measured as DP otoacoustic emission (DPOAE), and it also induces an excitatory response a...

journal_title：Journal of neurophysiology

authors： Abel C,Kössl M

更新日期：2009-03-01 00:00:00

abstract：:Based on kinematic properties and distinct substrates, there are different classes of eyelid movement described as eyeblinks. We investigate whether the eyelid movements made in response to a conditioned stimulus (CS) are a category of eyelid movements distinct from blinks. Human subjects received 60 trials of classic...

journal_title：Journal of neurophysiology

authors： Schade Powers A,Coburn-Litvak P,Evinger C

更新日期：2010-02-01 00:00:00

abstract：:Recent evidence implicates the superior colliculus (SC) in cognitive processes, such as target selection and control of spatial attention, in addition to the execution of saccadic eye movements. We report here the presence of a cognitive response in some cells in the SC in a task that requires the long-term associatio...

journal_title：Journal of neurophysiology

authors： Lee KM,Keller EL

更新日期：2006-06-01 00:00:00

abstract：:In this study, the representation of taste in the orbitofrontal cortex was investigated to determine whether or not a pleasant and an aversive taste have distinct or overlapping representations in this region. The pleasant stimulus used was sweet taste (1 M glucose), and the unpleasant stimulus was salt taste (0.1 M N...

journal_title：Journal of neurophysiology

authors： O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F

更新日期：2001-03-01 00:00:00

abstract：:Neural correlates of gap detection in three auditory cortical fields in the cat. Mimimum detectable gaps in noise in humans are independent of the position of the gap, whereas in cat primary auditory cortex (AI) they are position dependent. The position dependence in other cortical areas is not known and may resolve t...

journal_title：Journal of neurophysiology

authors： Eggermont JJ

更新日期：1999-05-01 00:00:00

abstract：:1. We examined the mean and standard deviation (SD) of interspike intervals (ISI) and the coefficient of variation (CV, the ratio of SD of ISI to mean ISI) of ISIs versus time to study discharge regularity of units in the dorsal cochlear nucleus (DCN) of decerebrate unanesthetized cats. The units were characterized by...

journal_title：Journal of neurophysiology

authors： Parham K,Kim DO

更新日期：1992-05-01 00:00:00

abstract：:1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...

journal_title：Journal of neurophysiology

authors： Behrends JC,ten Bruggencate G

更新日期：1993-02-01 00:00:00

abstract：:The relative motion between the surface of an object and our fingers produces patterns of skin deformation such as stretch, indentation, and vibrations. In this study, we hypothesized that motion-induced vibrations are combined with other tactile cues for the discrimination of tactile speed. Specifically, we hypothesi...

journal_title：Journal of neurophysiology

authors： Dallmann CJ,Ernst MO,Moscatelli A

更新日期：2015-12-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:Octopus arms, as well as other muscular hydrostats, are characterized by a very large number of degrees of freedom and a rich motion repertoire. Over the years, several attempts have been made to elucidate the interplay between the biomechanics of these organs and their control systems. Recent developments in electrop...

journal_title：Journal of neurophysiology

authors： Yekutieli Y,Mitelman R,Hochner B,Flash T

更新日期：2007-09-01 00:00:00

abstract：:Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...

journal_title：Journal of neurophysiology

authors： Ferger R,Pawlowsky K,Singheiser M,Wagner H

更新日期：2018-03-01 00:00:00

abstract：:Neurons in the inferior colliculus (IC) process acoustic information converging from inputs from almost all nuclei of the auditory brain stem. Despite its importance in auditory processing, little is known about the distribution of ion currents in IC neurons, namely the hyperpolarization-activated current Ih. This cur...

journal_title：Journal of neurophysiology

authors： Koch U,Grothe B

更新日期：2003-12-01 00:00:00

abstract：:Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this h...

journal_title：Journal of neurophysiology

authors： Kohn A,Metz C,Tommerdahl MA,Whitsel BL

更新日期：2002-12-01 00:00:00

abstract：:Stress-related alterations to the induction of hippocampal synaptic plasticity have been implicated in certain forms of psychiatric disorders. However, relatively little is known about such changes in other psychiatric disorders-related structures. We tested this possibility in one of such structures, the nucleus accu...

journal_title：Journal of neurophysiology

authors： Hugues S,Kessal K,Hunt MJ,Garcia R

更新日期：2003-11-01 00:00:00

abstract：:Seizures may cause brain damage due to mechanisms initiated by excessive excitatory synaptic transmission. One such mechanism is the activation of death-promoting intracellular cascades by the influx and the perturbed homeostasis of Ca2+. The neuroprotective effects of preventing the entry of Ca2+ from voltage-depende...

journal_title：Journal of neurophysiology

authors： Pelletier MR,Wadia JS,Mills LR,Carlen PL

更新日期：1999-06-01 00:00:00

abstract：:1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicite...

journal_title：Journal of neurophysiology

authors： Büsselberg D,Platt B,Michael D,Carpenter DO,Haas HL

更新日期：1994-04-01 00:00:00