Zn2+ blocks the NMDA- and Ca2+ -triggered postexposure current ipe in hippocampal pyramidal cells.

abstract：:1. Models of the saccadic system propose that there is an integration of the pulse signal, and there is good evidence that the integrator is reset gradually (Nichols and Sparks 1994, 1995). Other studies of the superior collicular contribution to the saccadic system have proposed a sensory, not motor, nature for its s...

journal_title：Journal of neurophysiology

authors： Kustov AA,Robinson DL

更新日期：1995-04-01 00:00:00

abstract：:Motor cortex plays a substantial role in driving movement, yet the details underlying this control remain unresolved. We analyzed the extent to which movement-related information could be extracted from single-trial motor cortical activity recorded while monkeys performed center-out reaching. Using information theoret...

journal_title：Journal of neurophysiology

authors： Golub MD,Yu BM,Schwartz AB,Chase SM

更新日期：2014-07-15 00:00:00

abstract：:Temporal and spatial correlations between auditory and visual stimuli facilitate the perception of unitary events and improve behavioral responses. However, it is not clear how combined visual and auditory information is processed in single neurons. Here we studied responses of multisensory neurons in the barn owl's o...

journal_title：Journal of neurophysiology

authors： Zahar Y,Reches A,Gutfreund Y

更新日期：2009-05-01 00:00:00

abstract：:Despite the peripheral and central immaturities that limit auditory processing in juvenile animals, they are able to lateralize sounds using binaural cues. This study explores a central mechanism that may compensate for these limitations during development. Interaural time and level difference processing by neurons in...

journal_title：Journal of neurophysiology

authors： Green JS,Sanes DH

更新日期：2005-12-01 00:00:00

abstract：:Following peripheral nerve injury, moderate daily exercise conducted on a level treadmill results in enhanced axon regeneration and modest improvements in functional recovery. If the exercise is conducted on an upwardly inclined treadmill, even more motor axons regenerate successfully and reinnervate muscle targets. W...

journal_title：Journal of neurophysiology

authors： Cannoy J,Crowley S,Jarratt A,Werts KL,Osborne K,Park S,English AW

更新日期：2016-09-01 00:00:00

abstract：:1. Effects of deafferentation of the tooth pulps of the posterior mandibular teeth were studied in single neurons recorded in the ipsilateral subnucleus caudalis of the trigeminal (V) spinal tract nucleus of adult cats and kittens. The functional properties of neurons in each anesthetized animal were determined electr...

journal_title：Journal of neurophysiology

authors： Hu JW,Sessle BJ

更新日期：1989-06-01 00:00:00

abstract：:In tasks requiring judgments about visual stimuli, humans exhibit repetition priming, responding with increased speed when a stimulus is repeated. Repetition priming might depend on repetition suppression, a phenomenon first observed in monkey inferotemporal cortex (IT) whereby, when a stimulus is repeated, the streng...

journal_title：Journal of neurophysiology

authors： McMahon DB,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:It is an essential feature for the visual system to keep track of self-motion to maintain space constancy. Therefore the saccadic system uses extraretinal information about previous saccades to update the internal representation of memorized targets, an ability that has been identified in behavioral and electrophysiol...

journal_title：Journal of neurophysiology

authors： Blohm G,Missal M,Lefèvre P

更新日期：2005-03-01 00:00:00

abstract：:Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the ...

journal_title：Journal of neurophysiology

authors： Peel TR,Johnston K,Lomber SG,Corneil BD

更新日期：2014-01-01 00:00:00

abstract：:1. The electrophysiological and pharmacological properties of slow afterpotentials in large layer V neurons from cat sensorimotor cortex were studied in an in vitro slice preparation using intracellular recording and single-microelectrode voltage clamp. These properties were used to assess the role of afterpotential m...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Spain WJ,Foehring RC,Chubb MC,Crill WE

更新日期：1988-02-01 00:00:00

abstract：:The contributions of the hyperpolarization-activated current, I(h), to generation of rhythmic activities are well described for various central neurons, particularly in thalamocortical circuits. In the present study, we investigated effects of a general anesthetic, propofol, on native I(h) in neurons of thalamus and c...

journal_title：Journal of neurophysiology

authors： Chen X,Shu S,Bayliss DA

更新日期：2005-12-01 00:00:00

abstract：:The possibility of using randomly generated stimulus intervals (with a Poisson distribution) to identify the type(s) of intrafusal fiber activated by the stimulation of single static gamma axons was tested in Peroneus tertius muscle spindles of anesthetized cats. Three patterns of random stimulation with different val...

journal_title：Journal of neurophysiology

authors： Petit J,Banks RW,Laporte Y

更新日期：1999-06-01 00:00:00

abstract：:The CNS controls reproduction through pulsatile secretion of gonadotropin-releasing hormone (GnRH). Episodic increases in the firing rate of unidentified hypothalamic neurons have been associated with downstream markers of GnRH secretion. Whether this episodic electrical activity is intrinsic to GnRH neurons, intrinsi...

journal_title：Journal of neurophysiology

authors： Nunemaker CS,DeFazio RA,Geusz ME,Herzog ED,Pitts GR,Moenter SM

更新日期：2001-07-01 00:00:00

abstract：:In the ventral tegmental area (VTA), interactions between dopamine (DA) and γ-aminobutyric acid (GABA) neurons are critical for regulating DA neuron activity and thus DA efflux. To provide a mechanistic explanation of how GABA neurons influence DA neuron firing, we developed a circuit model of the VTA. The model is ba...

journal_title：Journal of neurophysiology

authors： Morozova EO,Myroshnychenko M,Zakharov D,di Volo M,Gutkin B,Lapish CC,Kuznetsov A

更新日期：2016-10-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:For the first time in any vertebrate, in vivo responses of single olfactory receptor neurons to odorant mixtures were studied quantitatively. Extracellular electrophysiological response of 54 single olfactory receptor neurons from 23 channel catfish, Ictalurus punctatus, to binary mixtures of amino acids and to their ...

journal_title：Journal of neurophysiology

authors： Kang J,Caprio J

更新日期：1997-01-01 00:00:00

abstract：:Hypocretin-1 and -2 (Hcrt-1 and -2, also called orexin-A and -B) are newly identified neuropeptides synthesized by hypothalamic neurons. Defects in the Hcrt system underlie the sleep disorder narcolepsy, which is characterized by sleep fragmentation and the involuntary loss of muscle tone called cataplexy. Hcrt neuron...

journal_title：Journal of neurophysiology

authors： Peever JH,Lai YY,Siegel JM

更新日期：2003-05-01 00:00:00

abstract：:The caudal mesopallium (CM) is a cortical-level area in the songbird auditory pathway where selective, invariant responses to familiar songs emerge. To characterize the cell types that perform this computation, we made whole cell recordings from brain slices in juvenile zebra finches ( Taeniopygia guttata) of both sex...

journal_title：Journal of neurophysiology

authors： Chen AN,Meliza CD

更新日期：2018-03-01 00:00:00

abstract：:Abducens neurons undergo a dose-dependent synaptic blockade (either disinhibition or complete blockade) when tetanus neurotoxin (TeNT) is injected into the lateral rectus muscle at either a low (0.5) or a high dose (5 ng/kg). We studied the firing pattern and recruitment order in abducens neurons both in control and a...

journal_title：Journal of neurophysiology

authors： Pastor AM,Gonzalez-Forero D

更新日期：2003-10-01 00:00:00

abstract：:In the main olfactory bulb, several populations of granule cells (GCs) can be distinguished based on the soma location either superficially, interspersed with mitral cells within the mitral cell layer (MCL), or deeper, within the GC layer (GCL). Little is known about the physiological properties of superficial GCs (sG...

journal_title：Journal of neurophysiology

authors： Heinbockel T,Hamilton KA,Ennis M

更新日期：2007-04-01 00:00:00

abstract：:We have used electrophysiological techniques to document segmental differences in the pathways between the giant, escape command axons, lateral giants (LG) and medial giants (MG), and the nongiant, fast flexor (FF) motoneurons. We found no difference in the input from LG and MG axons to FF motoneurons in the posterior...

journal_title：Journal of neurophysiology

authors： Miller LA,Hagiwara G,Wine JJ

更新日期：1985-01-01 00:00:00

abstract：:Many neurons within prefrontal cortex exhibit a tonic discharge between visual stimulation and motor response. This delay activity may contribute to movement, memory, and vision. We studied delay activity sent from the frontal eye field (FEF) in prefrontal cortex to the superior colliculus (SC). We evaluated whether t...

journal_title：Journal of neurophysiology

authors： Sommer MA,Wurtz RH

更新日期：2001-04-01 00:00:00

abstract：:The discovery that neuroligin is a key protein involved in synapse formation offers the unprecedented opportunity to induce functional synapses between neurons and heterologous cells. We took this opportunity recording for the first-time synaptic currents in human embryonic kidney 293 (HEK293) cells transfected with n...

journal_title：Journal of neurophysiology

authors： Fu Z,Washbourne P,Ortinski P,Vicini S

更新日期：2003-12-01 00:00:00

abstract：:We have previously shown that control subjects use two distinct temporal strategies when stepping on an inclined surface during walking: one for level and 10 degrees surfaces and another for 20 and 30 degrees surfaces. These two temporal strategies were characterized by systematic shifts in the timing of muscle activi...

journal_title：Journal of neurophysiology

authors： Earhart GM,Bastian AJ

更新日期：2001-02-01 00:00:00

abstract：:The cerebellar control of orienting behavior toward visual targets was studied in the head-unrestrained cat by analyzing the deficits of saccadic gaze shifts after unilateral injection of muscimol in the caudal part of the fastigial nucleus (cFN). Gaze shifts are rendered strongly inaccurate by muscimol cFN inactivati...

journal_title：Journal of neurophysiology

authors： Goffart L,Pélisson D

更新日期：1998-04-01 00:00:00

abstract：:The purpose of this study was to examine which primary afferent fibers are sensitized to mechanical stimuli after an experimental surgical incision to the glabrous skin of the rat hindpaw. Afferent fibers teased from the L(5) dorsal root or the tibial nerve were recorded in anesthetized rats. The mechanical response p...

journal_title：Journal of neurophysiology

authors： Hämäläinen MM,Gebhart GF,Brennan TJ

更新日期：2002-02-01 00:00:00

abstract：:A seizure-paralysis repertoire characteristic of Drosophila "bang-sensitive" mutants can be evoked electroconvulsively in tethered flies, in which behavioral episodes are associated with synchronized spike discharges in different body parts. Flight muscle DLMs (dorsal longitudinal muscles) display a stereotypic sequen...

journal_title：Journal of neurophysiology

authors： Lee J,Wu CF

更新日期：2006-11-01 00:00:00

abstract：:Neural activity was recorded in the parietooccipital cortex while monkeys performed different tasks aimed at investigating visuomotor interactions of retinal, eye, and arm-related signals on neural activity. The tasks were arm reaching 1) to foveated targets; 2) to extrafoveal targets, with constant eye position; 3) w...

journal_title：Journal of neurophysiology

authors： Battaglia-Mayer A,Ferraina S,Mitsuda T,Marconi B,Genovesio A,Onorati P,Lacquaniti F,Caminiti R

更新日期：2000-04-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00

abstract：:Fast inhibitory synaptic transmission in the medial vestibular nucleus (MVN) is mediated by GABA(A) receptors (GABA(A)Rs) and glycine receptors (GlyRs). To assess their relative contribution to inhibition in the MVN, we recorded miniature inhibitory postsynaptic currents (mIPSCs) in physiologically characterized type ...

journal_title：Journal of neurophysiology

authors： Camp AJ,Callister RJ,Brichta AM

更新日期：2006-05-01 00:00:00