Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs.

abstract：:The discharge of muscle spindle afferents from monkey spindle afferents from monkey jaw-closing muscles was studied during mastication of natural foods by extracellular recording from the fibers or cell bodies of the tract and mesencephalic nucleus of the fifth nerve. In all, 39 muscle afferents were studied. The spin...

journal_title：Journal of neurophysiology

authors： Goodwin GM,Luschei ES

更新日期：1975-05-01 00:00:00

abstract：:Neuron loss, axon sprouting, and the formation of new synaptic circuits have been hypothesized to contribute to seizures in temporal lobe epilepsy (TLE). Using the kainate-treated rat, we examined how alterations in the density of CA1 pyramidal cells and interneurons, and subsequent sprouting of CA1 pyramidal cell axo...

journal_title：Journal of neurophysiology

authors： Smith BN,Dudek FE

更新日期：2001-01-01 00:00:00

abstract：:The mechanisms of irregular firing of spontaneous action potentials in neurons from the rat suprachiasmatic nucleus (SCN) were studied in hypothalamic slices using cell-attached and whole cell recording. The firing pattern of spontaneous action potentials could be divided into regular and irregular, based on the inter...

journal_title：Journal of neurophysiology

authors： Kononenko NI,Dudek FE

更新日期：2004-01-01 00:00:00

abstract：:Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...

journal_title：Journal of neurophysiology

authors： Marinovic W,de Rugy A,Lipp OV,Tresilian JR

更新日期：2013-02-01 00:00:00

abstract：:1. A generalized three-dimensional state space model of visual vestibular interaction was developed. Matrix and dynamical system operators associated with inputs from the semicircular canals, otolith velocity estimator, and the visual system have been incorporated into the model, which focus on their relationship to t...

journal_title：Journal of neurophysiology

authors： Raphan T,Sturm D

更新日期：1991-10-01 00:00:00

abstract：:Neurons constituting the pacemaker of circadian rhythms, located in the suprachiasmatic nucleus, generate spontaneous firing patterns that change across the day-night cycle. Their average spontaneous firing rate is considered an important functional marker of clock activity because it is highest during daytime and low...

journal_title：Journal of neurophysiology

authors： Pennartz CM,Bierlaagh MA,Geurtsen AM

更新日期：1997-10-01 00:00:00

abstract：:1. Baclofen increases transient light responses of amacrine and ganglion cells despite acting as a classical inhibitory transmitter to both hyperpolarize and shunt these cells. 2. This effect seems to occur at the level of the inner retina and appears not to be due to an additional input from bipolar cells. 3. In some...

journal_title：Journal of neurophysiology

authors： Bai SH,Slaughter MM

更新日期：1989-02-01 00:00:00

abstract：:We previously reported that neurons in the mediodorsal thalamic nucleus (MD) are topographically organized and express spatial and nonspatial coding properties similar to those of the prefrontal areas with which they are connected. In the course of mapping the dorsal thalamus, we also studied neurons in a subset of th...

journal_title：Journal of neurophysiology

authors： Tanibuchi I,Goldman-Rakic PS

更新日期：2005-01-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:Evidence first described in reduced animal models over 100 years ago led to deductions about the control of locomotion through spinal locomotor central pattern-generating (CPG) networks. These discoveries in nature were contemporaneous with another form of deductive reasoning found in popular culture, that of Arthur C...

journal_title：Journal of neurophysiology

authors： Klarner T,Zehr EP

更新日期：2018-07-01 00:00:00

abstract：:The effects of neuronal density on morphological and functional attributes of the evolving networks were studied in cultured dissociated hippocampal neurons. Plating at different densities affected connectivity among the neurons, such that sparse networks exhibited stronger synaptic connections between pairs of record...

journal_title：Journal of neurophysiology

authors： Ivenshitz M,Segal M

更新日期：2010-08-01 00:00:00

abstract：:The reward value of a stimulus can be learned through two distinct mechanisms: reinforcement learning through repeated stimulus-reward pairings and abstract inference based on knowledge of the task at hand. The reinforcement mechanism is often identified with midbrain dopamine neurons. Here we show that a neural pathw...

journal_title：Journal of neurophysiology

authors： Bromberg-Martin ES,Matsumoto M,Hong S,Hikosaka O

更新日期：2010-08-01 00:00:00

abstract：:N-arachidonoyldopamine (NADA) is an endogenous molecule found in the nervous system that is capable of acting as a vanilloid agonist via the TRPV1 receptor and as a cannabinoid agonist via the CB1 receptor. Using anesthetized rats, we investigated the neural correlates of behavioral thermal hyperalgesia produced by NA...

journal_title：Journal of neurophysiology

authors： Huang SM,Walker JM

更新日期：2006-02-01 00:00:00

abstract：:The mechanism(s) of olfactory transduction in invertebrates remains to be fully understood. In lobster olfactory receptor neurons (ORNs), a nonselective sodium-gated cation (SGC) channel, a presumptive transient receptor potential (TRP)C channel homolog, plays a crucial role in olfactory transduction, at least in part...

journal_title：Journal of neurophysiology

authors： Pezier A,Bobkov YV,Ache BW

更新日期：2009-03-01 00:00:00

abstract：:Microsleeps are brief episodes of arousal level decrease manifested through behavioral signs. Brain activity during microsleep in the presence of external stimulus remains poorly understood. In this study, we sought to understand neural responses to auditory stimulation during microsleep. We gave participants the simp...

journal_title：Journal of neurophysiology

authors： Yong Z,Tan JH,Hsieh PJ

更新日期：2019-12-01 00:00:00

abstract：:How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed...

journal_title：Journal of neurophysiology

authors： Hammerbeck U,Yousif N,Greenwood R,Rothwell JC,Diedrichsen J

更新日期：2014-01-01 00:00:00

abstract：:We elicited repetitive discharge in hypoglossal motoneurons recorded in slices of rat brain stem using a combination of a suprathreshold injected current step with superimposed noise to mimic the synaptic drive likely to occur during physiological activation. The effects of repetitive en mass stimulation of afferent n...

journal_title：Journal of neurophysiology

authors： Türker KS,Powers RK

更新日期：1999-08-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:Organization of spinal motor output has become of interest for investigating differential activation of lumbar and sacral motor pools during locomotor tasks. Motor pools are associated with functional grouping of motoneurons of the lower limb muscles. Here we examined how the spatiotemporal organization of lumbar and ...

journal_title：Journal of neurophysiology

authors： Dewolf AH,Ivanenko YP,Zelik KE,Lacquaniti F,Willems PA

更新日期：2019-08-01 00:00:00

abstract：:1. Several heart interneurons (HN cells) of the leech nerve cord have impulse-initiation sites in every segmental ganglion through which their single axons pass. All these initiation sites are capable of producing rhythmic impulse bursts. However, under normal conditions a dominant primary initiation site in the gangl...

journal_title：Journal of neurophysiology

authors： Calabrese RL

更新日期：1980-11-01 00:00:00

abstract：:Beta-band oscillations are a dominant feature in the sensorimotor system, which includes movement-related beta desynchronization (MRBD) during the preparation and execution phases of movement and postmovement beta synchronization (PMBS) on movement cessation. Many studies have linked this rhythm to motor functions. Ho...

journal_title：Journal of neurophysiology

authors： Zhang X,Li H,Xie T,Liu Y,Chen J,Long J

更新日期：2020-08-01 00:00:00

abstract：:1. We investigated the effects of metabotropic glutamate (mGlu) receptor activation on intracellular Ca2+ concentration ([Ca2+]i) in the soma and dendrites of hippocampal CA1 pyramidal neurons. Changes in [Ca2+]i were measured using confocal imaging simultaneously with whole-cell recording techniques. Differences in [...

journal_title：Journal of neurophysiology

authors： Jaffe DB,Brown TH

更新日期：1994-07-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:Two of the biggest health problems facing us today are addiction to nicotine and the increased prevalence of obesity. Interestingly, nicotine attenuates obesity, but the underlying mechanism is not clear. Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomel...

journal_title：Journal of neurophysiology

authors： Huang H,Xu Y,van den Pol AN

更新日期：2011-09-01 00:00:00

abstract：:Neurons in monkey orbitofrontal cortex (OF) are known to respond to reward-predicting cues with a strength that depends on the value of the predicted reward as determined 1) by intrinsic attributes including size and quality and 2) by extrinsic factors including the monkey's state of satiation and awareness of what ot...

journal_title：Journal of neurophysiology

authors： Roesch MR,Olson CR

更新日期：2005-10-01 00:00:00

abstract：:Endocannabinoids released from the postsynaptic neuronal membrane can activate presynaptic CB1 receptors and inhibit neurotransmitter release. In hippocampal slices, depolarization of the CA1 pyramidal neurons elicits an endocannabinoid-mediated inhibition of gamma-aminobutyric acid release known as depolarization-ind...

journal_title：Journal of neurophysiology

authors： Sheinin A,Talani G,Davis MI,Lovinger DM

更新日期：2008-08-01 00:00:00

abstract：:Membrane retrieval following exocytosis in synaptic terminals is fast and compensatory, however, little is known about the factors that regulate or contribute to this special form of endocytosis. We used whole-terminal capacitance measurements to examine the effect of hydrostatic pressure on compensatory endocytosis i...

journal_title：Journal of neurophysiology

authors： Heidelberger R,Zhou ZY,Matthews G

更新日期：2002-11-01 00:00:00

abstract：:1. Neuronal mechanisms for decoding sound azimuth and angular movement were studied by recordings of several single units in parallel in the core areas of the auditory cortex of the macaque monkey. The activity of 180 units was recorded during the presentation of moving and static sound stimuli. Both the activity of s...

journal_title：Journal of neurophysiology

authors： Ahissar M,Ahissar E,Bergman H,Vaadia E

更新日期：1992-01-01 00:00:00

abstract：:The macaque middle temporal area (MT) is exquisitely sensitive to visual motion and there is a large amount of evidence that neural activity in MT is tightly correlated with the perception of motion. The mechanisms by which MT neurons achieve their directional selectivity, however, have received considerably less atte...

journal_title：Journal of neurophysiology

authors： Krekelberg B,Albright TD

更新日期：2005-05-01 00:00:00

abstract：:We used laser scanning photostimulation through a focused UV laser of caged glutamate in an in vitro slice preparation through the rat's somatosensory thalamus to study topography and connectivity between the thalamic reticular nucleus and ventral posterior lateral nucleus. This enabled us to focally stimulate the som...

journal_title：Journal of neurophysiology

authors： Lam YW,Sherman SM

更新日期：2005-10-01 00:00:00