Enhancement of spontaneous and heat-evoked activity in spinal nociceptive neurons by the endovanilloid/endocannabinoid N-arachidonoyldopamine (NADA).

abstract：:The countermanding saccade task has been used in many studies to investigate the neural mechanisms that underlie the decision to execute or restrain rapid eye movements. In this task, the presentation of a saccade target is sometimes followed by the appearance of a stop cue that indicates that the subject should cance...

journal_title：Journal of neurophysiology

authors： Walton MM,Gandhi NJ

更新日期：2006-10-01 00:00:00

abstract：:Here we report on the development of a novel neuroelectronic interface consisting of an array of noninvasive gold-mushroom-shaped microelectrodes (gMmicroEs) that practically provide intracellular recordings and stimulation of many individual neurons, while the electrodes maintain an extracellular position. The develo...

journal_title：Journal of neurophysiology

authors： Hai A,Shappir J,Spira ME

更新日期：2010-07-01 00:00:00

abstract：:1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

journal_title：Journal of neurophysiology

authors： Pflug R,Nelson R,Ahnelt PK

更新日期：1990-08-01 00:00:00

abstract：:The structural elements of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) signaling pathway have been described in the vestibular peripheral system. However, the functions of NO in the vestibular endorgans are still not clear. We evaluated the action of NO on the Ca(2+) currents in hair cells isolated from ...

journal_title：Journal of neurophysiology

authors： Almanza A,Navarrete F,Vega R,Soto E

更新日期：2007-02-01 00:00:00

abstract：:Cross-orientation suppression was measured in human primary visual cortex (V1) to test the normalization model. Subjects viewed vertical target gratings (of varying contrasts) with or without a superimposed horizontal mask grating (fixed contrast). We used functional magnetic resonance imaging (fMRI) to measure the ac...

journal_title：Journal of neurophysiology

authors： Brouwer GJ,Heeger DJ

更新日期：2011-11-01 00:00:00

abstract：:The vestibular system operates in a push-pull fashion using signals from both labyrinths and an intricate bilateral organization. Unilateral vestibular lesions cause well-characterized motor deficits that are partially compensated over time and whose neural correlates have been traced in the mean response modulation o...

journal_title：Journal of neurophysiology

authors： Yu XJ,Thomassen JS,Dickman JD,Newlands SD,Angelaki DE

更新日期：2014-08-15 00:00:00

abstract：:We have used a computer-based mathematical model of alpha-motoneurons and of group Ia synaptic input to them, based on anatomical and electrophysiological data from the cat spinal cord, in order to examine the effects of variations in neuron size and input resistance and of conductance magnitude and duration on the ge...

journal_title：Journal of neurophysiology

authors： Lev-Tov A,Miller JP,Burke RE,Rall W

更新日期：1983-08-01 00:00:00

abstract：:Most of what we know about the neural control of gaze comes from experiments in head-fixed animals, but several "head-free" studies have suggested that fixing the head dramatically alters the apparent gaze command. We directly investigated this issue by quantitatively comparing head-fixed and head-free gaze trajectori...

journal_title：Journal of neurophysiology

authors： Martinez-Trujillo JC,Klier EM,Wang H,Crawford JD

更新日期：2003-10-01 00:00:00

abstract：:In acute experiments performed in decerebrated and spinalized (T13) cats, an intraspinal injection of clonidine, a noradrenergic agonist, restricted to mid-lumbar segments L3-L4, can induce hindlimb locomotion, whereas yohimbine, a noradrenergic antagonist, can block spinal locomotion, and a second spinal lesion at L4...

journal_title：Journal of neurophysiology

authors： Langlet C,Leblond H,Rossignol S

更新日期：2005-05-01 00:00:00

abstract：:Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimula...

journal_title：Journal of neurophysiology

authors： Lewis RF

更新日期：2016-12-01 00:00:00

abstract：:To explore neural mechanisms how olfactory information is processed in the brain and finally converted into behavior, it would be useful to have isolated whole brains that include both olfactory organs and motor output. In the present study, we identified an in vitro index of odor-evoked behavior in the terrestrial mo...

journal_title：Journal of neurophysiology

authors： Inoue T,Inokuma Y,Watanabe S,Kirino Y

更新日期：2004-01-01 00:00:00

abstract：:The ability of individuals to adapt locomotion to constraints associated with the complex environments normally encountered in everyday life is paramount for survival. Here, we tested the ability of 24 healthy young adults to adapt to a rightward prism shift (∼11.3°) while either walking and stepping to targets (i.e.,...

journal_title：Journal of neurophysiology

authors： Alexander MS,Flodin BW,Marigold DS

更新日期：2011-08-01 00:00:00

abstract：:Falls during walking are a major cause of poststroke injury, and walking faster may decrease the ability to recover following a gait perturbation. We compared gait stability between high-functioning poststroke individuals and controls and evaluated the effect of gait speed on gait stability. Ten stroke subjects and te...

journal_title：Journal of neurophysiology

authors： Krasovsky T,Lamontagne A,Feldman AG,Levin MF

更新日期：2013-01-01 00:00:00

abstract：:1. Neurons (n = 142) were recorded with extracellular micropipettes in the parabrachial (PB) area, in the anesthetized rat, some of them being antidromically driven from the centralis nucleus of the amygdala (Ce). The spontaneous activity of these neurons was low, (10th percentile < median frequency < 90th percentile;...

journal_title：Journal of neurophysiology

authors： Bernard JF,Huang GF,Besson JM

更新日期：1994-05-01 00:00:00

abstract：:Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

journal_title：Journal of neurophysiology

authors： Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

更新日期：2018-07-01 00:00:00

abstract：:Regional blood oxygenation in the cerebellum and posterior cerebral cortices was monitored with functional magnetic resonance imaging (fMRI) at four Tesla while 16 normal subjects performed three tasks with identical visual stimulation: fixation; attention focused upon either stimulus shape or color and sustained duri...

journal_title：Journal of neurophysiology

authors： Le TH,Pardo JV,Hu X

更新日期：1998-03-01 00:00:00

abstract：:1. Using patch-clamp recordings, expression of voltage-activated ion channels by identified glial cells in situ was studied in hippocampal slices derived from 5- to 24-day-old rats. Glial cells were filled with Lucifer yellow during recording, and were identified by staining for glial fibrillary acidic protein (GFAP)....

journal_title：Journal of neurophysiology

authors： Sontheimer H,Waxman SG

更新日期：1993-11-01 00:00:00

abstract：:The primary motor cortex (MI) commands motor output after kinematics are planned from goals, thought to occur in a larger premotor network. However, there is a growing body of evidence that MI is involved in processes beyond action generation, and neuronal subpopulations may perform computations related to cue-to-acti...

journal_title：Journal of neurophysiology

authors： Rao NG,Donoghue JP

更新日期：2014-01-01 00:00:00

abstract：:The amines dopamine (DA), serotonin (5-HT), and octopamine (Oct) each elicit a distinctive motor pattern from a quiescent pyloric network in the lobster stomatogastric ganglion (STG). We previously have demonstrated that these amines alter the synaptic strength at multiple, distributed sites within the pyloric network...

journal_title：Journal of neurophysiology

authors： Johnson BR,Harris-Warrick RM

更新日期：1997-12-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the ef...

journal_title：Journal of neurophysiology

authors： Jang HJ,Cho KH,Park SW,Kim MJ,Yoon SH,Rhie DJ

更新日期：2012-01-01 00:00:00

abstract：:The discovery that neuroligin is a key protein involved in synapse formation offers the unprecedented opportunity to induce functional synapses between neurons and heterologous cells. We took this opportunity recording for the first-time synaptic currents in human embryonic kidney 293 (HEK293) cells transfected with n...

journal_title：Journal of neurophysiology

authors： Fu Z,Washbourne P,Ortinski P,Vicini S

更新日期：2003-12-01 00:00:00

abstract：:1. Presynaptic activity of identified primary afferents from flexor, extensor, and bifunctional hindlimb muscles was studied with intra-axonal recordings during fictive locomotion. Fictive locomotion appeared spontaneously in decorticate cats (n = 9), with stimulation of the mesencephalic locomotor region (n = 4), and...

journal_title：Journal of neurophysiology

authors： Gossard JP,Cabelguen JM,Rossignol S

更新日期：1991-04-01 00:00:00

abstract：:1. The onset of visual activity in the superficial layers of the cat superior colliculus begins abruptly at about 6 days postnatal (DPN), just before natural eye opening. Despite the presence of many inactive sites at this time, the systematic nature of the superior colliculus visuotopy is already evident. The number ...

journal_title：Journal of neurophysiology

authors： Kao CQ,McHaffie JG,Meredith MA,Stein BE

更新日期：1994-07-01 00:00:00

abstract：:Cellular mechanisms underlying learning and memory were investigated in the octopus using a brain slice preparation of the vertical lobe, an area of the octopus brain involved in learning and memory. Field potential recordings revealed long-term potentiation (LTP) of glutamatergic synaptic field potentials similar to ...

journal_title：Journal of neurophysiology

authors： Hochner B,Brown ER,Langella M,Shomrat T,Fiorito G

更新日期：2003-11-01 00:00:00

abstract：:Spontaneous calcium oscillations in mushroom bodies of late stage pupal and adult Drosophila brains have been implicated in memory consolidation during olfactory associative learning. This study explores the cellular mechanisms regulating calcium dynamics in Kenyon cells, principal neurons in mushroom bodies. Fura-2 i...

journal_title：Journal of neurophysiology

authors： Jiang SA,Campusano JM,Su H,O'Dowd DK

更新日期：2005-07-01 00:00:00

abstract：:1. Monkeys with large unilateral surgical ablations of striate cortex, sustained either in adulthood or at 5-6 wk of age, were trained on an oculomotor detection and localization task and tested with visual stimuli in the hemifields ipsilateral and contralateral to the lesion 2-5 yr after surgery. 2. Monkeys with lesi...

journal_title：Journal of neurophysiology

authors： Moore T,Rodman HR,Repp AB,Gross CG,Mezrich RS

更新日期：1996-12-01 00:00:00

abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...

journal_title：Journal of neurophysiology

authors： Moorman DE,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:The spinal cord has been well established as the site of generation of the locomotor rhythm in vertebrates, but studies have suggested that the caudal hindbrain in larval fish and amphibians can also generate locomotor rhythms. Here, we investigated whether the caudal hindbrain of the adult lamprey ( Petromyzon marinu...

journal_title：Journal of neurophysiology

authors： Buchanan JT

更新日期：2018-05-01 00:00:00

abstract：:Spontaneous synchronized bursts of activity play an essential role in the maturation and plasticity of neuronal networks. To investigate the cellular properties that enable spontaneous network activity, we used dissociated cultures of hippocampal neurons that express prolonged network activity bursts. Acute exposure t...

journal_title：Journal of neurophysiology

authors： Cohen D,Segal M

更新日期：2009-04-01 00:00:00

abstract：:The structural features of a synaptic connection between central neurons play an important role in determining the strength of the connection. In the present study, we have examined the relationship between the structural and functional properties of glycinergic synapses in the rat spinal cord. We have analyzed the st...

journal_title：Journal of neurophysiology

authors： Oleskevich S,Alvarez FJ,Walmsley B

更新日期：1999-07-01 00:00:00