Postnatal development of a persistent Na+ current in pyramidal neurons from rat sensorimotor cortex.

abstract：:Recent work has investigated the link between motor learning and sensory function in arm movement control. A number of findings are consistent with the idea that motor learning is associated with systematic changes to proprioception (Haith A, Jackson C, Mial R, Vijayakumar S. Adv Neural Inf Process Syst 21: 593-600, 2...

journal_title：Journal of neurophysiology

authors： Wong JD,Kistemaker DA,Chin A,Gribble PL

更新日期：2012-12-01 00:00:00

abstract：:With each eye movement, stationary objects in the world change position on the retina, yet we perceive the world as stable. Spatial updating, or remapping, is one neural mechanism by which the brain compensates for shifts in the retinal image caused by voluntary eye movements. Remapping of a visual representation is b...

journal_title：Journal of neurophysiology

authors： Merriam EP,Genovese CR,Colby CL

更新日期：2007-02-01 00:00:00

abstract：:1. We investigated gamma-aminobutyric acid (GABA) receptors using thin slice patch-clamp techniques in the swellings along axons of posterior pituitary nerve terminals. 2. Activation of the nerve terminal GABAA receptor induced a mean conductance change of 1.5 nS. Normalizing to area gave a mean conductance density of...

journal_title：Journal of neurophysiology

authors： Zhang SJ,Jackson MB

更新日期：1995-03-01 00:00:00

abstract：:Metabotropic receptors modulate numerous cellular processes by intracellular Ca2+ signaling, but less is known about their role in regulating mitochondrial metabolic function within the CNS. In this study, we demonstrate in area CA3 of rat organotypic hippocampal slice cultures that glutamatergic, serotonergic, and mu...

journal_title：Journal of neurophysiology

authors： Kann O,Kovács R,Heinemann U

更新日期：2003-08-01 00:00:00

abstract：:Substance P initiates locomotion when injected in the brain stem of mammals. This study examined the possible role of this peptide on the supraspinal locomotor command system in lampreys. Substance P was bath applied or locally injected into an in vitro isolated brain stem, and the effects of the drug were examined on...

journal_title：Journal of neurophysiology

authors： Brocard F,Bardy C,Dubuc R

更新日期：2005-04-01 00:00:00

abstract：:The motor pathway responsible for the complex vocalizations of songbirds has been extensively characterized, both in terms of intrinsic and synaptic physiology in vitro and in terms of the spatiotemporal patterns of neural activity in vivo. However, the relationship between the neural architecture of the song motor pa...

journal_title：Journal of neurophysiology

authors： Abarbanel HD,Gibb L,Mindlin GB,Talathi S

更新日期：2004-07-01 00:00:00

abstract：:Synaptic plasticity can last from a fraction of a second to weeks depending on how it was induced. The mechanisms that underlie short-, intermediate-, and long-term plasticity have been intensively studied at central synapses of both vertebrates and invertebrates; however, peripheral plasticity has not received as muc...

journal_title：Journal of neurophysiology

authors： Fox LE,Lloyd PE

更新日期：2002-04-01 00:00:00

abstract：:1. The heart of the nudibranch mollusc Archidoris montereyensis is uniquely responsive to regulation by identifiable cardiac motor neurons. The neurotransmitters mediating the strong excitatory and inhibitory actions of the neurons are unknown. 2. In this study we developed an infused, in vitro preparation of the Arch...

journal_title：Journal of neurophysiology

authors： Wiens BL,Brownell PH

更新日期：1995-10-01 00:00:00

abstract：:The superior colliculus (SC) provides signals for the generation of saccades via a direct pathway to the brain stem burst generator (BG). In addition, it sends saccade-related activity to the BG indirectly through the cerebellum via a relay in the nucleus reticularis tegmenti pontis (NRTP). Lesions of the oculomotor v...

journal_title：Journal of neurophysiology

authors： Kaneko CR,Fuchs AF

更新日期：2006-06-01 00:00:00

abstract：:A preparation is described in which the thoracic ganglia of the crayfish are isolated together with the thoracocoxal muscle receptor organ (TCMRO) of the fourth leg. This preparation allows intracellular analysis of both centrally generated and reflex activity in leg motor neurons (MNs). The isolated thoracic ganglia ...

journal_title：Journal of neurophysiology

authors： Sillar KT,Skorupski P

更新日期：1986-04-01 00:00:00

abstract：:The relationship between neck muscle electromyography (EMG) and torsional head rotation (about the nasooccipital axis) is difficult to assess during normal gaze behaviors with the head upright. Here, we induced acute head tilts similar to cervical dystonia (torticollis) in two monkeys by electrically stimulating 20 in...

journal_title：Journal of neurophysiology

authors： Farshadmanesh F,Byrne P,Wang H,Corneil BD,Crawford JD

更新日期：2012-12-01 00:00:00

abstract：:The lateral hypothalamus (LH), which plays a role in homeostatic functions such as appetite regulation, is also linked to arousal and motivational behavior. However, little is known about how these components are encoded in the LH. Thus cynomolgus monkeys were conditioned with two distinct contexts, i.e., an appetitiv...

journal_title：Journal of neurophysiology

authors： Noritake A,Nakamura K

更新日期：2019-02-01 00:00:00

abstract：:We studied the eye movements evoked by applying small amounts of current (2-50 microA) within the oculomotor vermis of two monkeys. We first compared the eye movements evoked by microstimulation applied either during maintained pursuit or during fixation. Smooth, pursuitlike changes in eye velocity caused by the micro...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ,Miles FA

更新日期：1998-10-01 00:00:00

abstract：:In free viewing, the eyes return to previously visited locations rather frequently, even though the attentional and memory-related processes controlling eye-movement show a strong antirefixation bias. To overcome this bias, a special refixation triggering mechanism may have to be recruited. We probed the neural eviden...

journal_title：Journal of neurophysiology

authors： Nikolaev AR,Meghanathan RN,van Leeuwen C

更新日期：2018-11-01 00:00:00

abstract：:Primary afferent fibers from the electroreceptors of mormyrid electric fish use a latency code to signal the intensity of electrical current evoked by the fish's own electric organ discharge (EOD). The afferent fibers terminate centrally in the deep and superficial granular layers of the electrosensory lobe with morph...

journal_title：Journal of neurophysiology

authors： Zhang J,Han VZ,Meek J,Bell CC

更新日期：2007-03-01 00:00:00

abstract：:Silent synapses are excitatory synapses endowed exclusively with N-methyl-D-aspartate (NMDA) responses that have been proposed to acquire alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) responses during development and after long-term potentiation (LTP). These synapses are functionally silent because o...

journal_title：Journal of neurophysiology

authors： Losi G,Prybylowski K,Fu Z,Luo JH,Vicini S

更新日期：2002-03-01 00:00:00

abstract：:Many critically ill patients in intensive care units suffer from an infection-induced whole body inflammatory state known as sepsis, which causes severe weakness in patients who survive. The mechanisms by which sepsis triggers intensive care unit-acquired weakness (ICUAW) remain unclear. Currently, research into ICUAW...

journal_title：Journal of neurophysiology

authors： Nardelli P,Khan J,Powers R,Cope TC,Rich MM

更新日期：2013-04-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:The neocortex generates short epochs of persistent activity called up states, which are associated with changes in cellular and network excitability. Using somatosensory thalamocortical slices, we studied the impact of persistent cortical activity during spontaneous up states on intrinsic cellular excitability (input ...

journal_title：Journal of neurophysiology

authors： Rigas P,Castro-Alamancos MA

更新日期：2009-07-01 00:00:00

abstract：:Experiments were performed on human elbow flexor and extensor muscles and jaw-opening and -closing muscles to observe the effect on rhythmic movements of sudden loading. The load was provided by an electromagnetic device, which simulated the appearance of a smoothly increasing spring-like load. The responses to this l...

journal_title：Journal of neurophysiology

authors： Abbink JH,van der Bilt A,Bosman F,van der Glas HW,Erkelens CJ,Klaassen MF

更新日期：1999-09-01 00:00:00

abstract：:1. A task was used by Posner (1980) to measure shifts of attention that occurred covertly, in the absence of an eye movement or other orienting response. This paradigm was used here to assess the nature of covert attentional orienting in monkeys to develop an animal model for neurophysiological studies. Shifts of atte...

journal_title：Journal of neurophysiology

authors： Bowman EM,Brown VJ,Kertzman C,Schwarz U,Robinson DL

更新日期：1993-07-01 00:00:00

abstract：:The objectives of this study were to probe the contribution of spinal neuron persistent sodium conductances to reflex hyperexcitability in human chronic spinal cord injury. The intrinsic excitability of spinal neurons provides a novel target for medical intervention. Studies in animal models have shown that persistent...

journal_title：Journal of neurophysiology

authors： Theiss RD,Hornby TG,Rymer WZ,Schmit BD

更新日期：2011-06-01 00:00:00

abstract：:Upon prolonged viewing of a sinusoidal grating, the visual system is selectively desensitized to the spatial frequency of the grating, while the sensitivity to other spatial frequencies remains largely unaffected. This technique, known as pattern adaptation, has been so central to the psychophysical study of the mecha...

journal_title：Journal of neurophysiology

authors： Hegdé J

更新日期：2009-10-01 00:00:00

abstract：:1. A compartmental model was employed to investigate the electrical behavior of a dendritic spine having excitable membrane at the spine head. Here we used the Hodgkin and Huxley equations to generate excitable membrane properties; in some cases the kinetics were modified to get a longer duration action potential. Pas...

journal_title：Journal of neurophysiology

authors： Segev I,Rall W

更新日期：1988-08-01 00:00:00

abstract：:Patch clamp is the main technique for measuring electrical properties of individual cells. Since its discovery in 1976 by Neher and Sakmann, patch clamp has been instrumental in broadening our understanding of the fundamental properties of ion channels and synapses in neurons. The conventional patch-clamp method requi...

journal_title：Journal of neurophysiology

authors： Wu 吴秋雨 Q,Kolb I,Callahan BM,Su Z,Stoy W,Kodandaramaiah SB,Neve R,Zeng H,Boyden ES,Forest CR,Chubykin AA

更新日期：2016-10-01 00:00:00

abstract：:Gamma-aminobutyric acid type A (GABAA) receptors expressed within the medial preoptic area (mPOA) are known to play a critical role in regulating sexual and neuroendocrine functions. In the rat brain, high levels of expression of the gamma1 subunit mRNA of the GABAA receptor are restricted to a limited number of regio...

journal_title：Journal of neurophysiology

authors： Nett ST,Jorge-Rivera JC,Myers M,Clark AS,Henderson LP

更新日期：1999-01-01 00:00:00

abstract：:We developed a physiologically realistic mathematical model of the Golgi tendon organ (GTO) whose elements correspond to anatomical features of the biological receptor. The mechanical interactions of these elements enable it to capture all salient aspects of GTO afferent behavior reported in the literature. The model ...

journal_title：Journal of neurophysiology

authors： Mileusnic MP,Loeb GE

更新日期：2006-10-01 00:00:00

abstract：:The countermanding saccade task has been used in many studies to investigate the neural mechanisms that underlie the decision to execute or restrain rapid eye movements. In this task, the presentation of a saccade target is sometimes followed by the appearance of a stop cue that indicates that the subject should cance...

journal_title：Journal of neurophysiology

authors： Walton MM,Gandhi NJ

更新日期：2006-10-01 00:00:00

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00

abstract：:1. The discharge patterns of 40 neurons in the central nucleus of the inferior colliculus (ICC) of the chinchilla were evaluated before and after acute cochlea trauma from intense tone exposure. Single-unit recordings were obtained from neurons in the ICC contralateral to the sound-stimulated ear. Cochlear trauma was ...

journal_title：Journal of neurophysiology

authors： Wang J,Salvi RJ,Powers N

更新日期：1996-01-01 00:00:00