Silent synapses in developing cerebellar granule neurons.

abstract：:1. High-voltage-activated Ca2+ currents [ICa(HVA)] were studied in immunolabeled mouse retinal ganglion neurons (RGNs) to elucidate channel-specific components and their developmental changes in vitro. 2. Neurons were dissociated at postnatal day 5. RGNs were selected for electrophysiological measurements by vital lab...

journal_title：Journal of neurophysiology

authors： Rothe T,Grantyn R

更新日期：1994-11-01 00:00:00

abstract：:Low-intensity alternating electric fields applied to the scalp are capable of modulating cortical activity and brain functions, but the underlying mechanisms remain largely unknown. Here, we report two distinct components of voltage-sensitive dye signals induced by low-intensity, alternating electric fields in rodent ...

journal_title：Journal of neurophysiology

authors： Xu W,Wolff BS,Wu JY

更新日期：2014-11-15 00:00:00

abstract：:In recent years a small number of studies have applied functional imaging techniques to investigate visual responses in the human superior colliculus (SC), but few have investigated its oculomotor functions. Here, in two experiments, we examined activity associated with endogenous saccade preparation. We used 3-T fMRI...

journal_title：Journal of neurophysiology

authors： Furlan M,Smith AT,Walker R

更新日期：2015-08-01 00:00:00

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:Multimodal sensory integration facilitates the generation of a unified and coherent perception of the environment. It is now well established that unimodal sensory perceptions, such as vision, are improved in multisensory contexts. Whereas multimodal integration is primarily performed by dedicated multisensory brain r...

journal_title：Journal of neurophysiology

authors： McClure JP Jr,Polack PO

更新日期：2019-06-01 00:00:00

abstract：:Anatomical and physiological data have implicated the pretectal olivary nucleus (PON) as the midbrain relay for the pupillary light reflex in a variety of species. To determine the nature of the discharge of pretectal light reflex relay neurons, we recorded their activity in monkeys that were fixating a stationary spo...

journal_title：Journal of neurophysiology

authors： Pong M,Fuchs AF

更新日期：2000-08-01 00:00:00

abstract：:Responses to tones, clicks, and noise were recorded from chinchilla auditory-nerve fibers (ANFs). The responses to noise were analyzed by computing the zeroth-, first-, and second-order Wiener kernels (h0, h1, and h2). The h1s correctly predicted the frequency tuning and phases of responses to tones of ANFs with low c...

journal_title：Journal of neurophysiology

authors： Temchin AN,Recio-Spinoso A,van Dijk P,Ruggero MA

更新日期：2005-06-01 00:00:00

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00

abstract：:Serotonin [5-hydroxytryptamine (5-HT)] is a conspicuous neuromodulator of sensory-motor networks that affects a variety of neurons at different levels of the network hierarchy. Because of its many possible targets, it has been difficult to obtain a comprehensive picture of how 5-HT achieves its final modulatory output...

journal_title：Journal of neurophysiology

authors： Calviño MA,Iscla IR,Szczupak L

更新日期：2005-05-01 00:00:00

abstract：:The aim of this study was to examine how cat spinal motoneurons integrate the synaptic currents generated by the concurrent activation of large groups of presynaptic neurons. We obtained intracellular recordings from cat triceps surae motoneurons and measured the effects of repetitive activity in different sets of pre...

journal_title：Journal of neurophysiology

authors： Powers RK,Binder MD

更新日期：2000-01-01 00:00:00

abstract：:The cardiac ganglion (CG) of Homarus americanus is a central pattern generator that consists of two oscillatory groups of neurons: "small cells" (SCs) and "large cells" (LCs). We have shown that SCs and LCs begin their bursts nearly simultaneously but end their bursts at variable phases. This variability contrasts wit...

journal_title：Journal of neurophysiology

authors： Williams AH,Kwiatkowski MA,Mortimer AL,Marder E,Zeeman ML,Dickinson PS

更新日期：2013-05-01 00:00:00

abstract：:The vestibuloocular reflex (VOR) needs to modulate its gain depending on target distance to prevent retinal slip during head movements. We investigated gain modulation (context compensation) for binocular gaze stabilization in human subjects during voluntary yaw and pitch head rotations. Movements of each eye were rec...

journal_title：Journal of neurophysiology

authors： Medendorp WP,Van Gisbergen JA,Van Pelt S,Gielen CC

更新日期：2000-12-01 00:00:00

abstract：:To explore neural mechanisms how olfactory information is processed in the brain and finally converted into behavior, it would be useful to have isolated whole brains that include both olfactory organs and motor output. In the present study, we identified an in vitro index of odor-evoked behavior in the terrestrial mo...

journal_title：Journal of neurophysiology

authors： Inoue T,Inokuma Y,Watanabe S,Kirino Y

更新日期：2004-01-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:In the inferior colliculus (IC) of the big brown bat, a subpopulation of cells ( approximately 35%) are tuned to a narrow range of sound durations. Band-pass tuning for sound duration has not been seen at lower levels of the auditory pathway. Previous work suggests that it arises at the IC through the interaction of s...

journal_title：Journal of neurophysiology

authors： Casseday JH,Ehrlich D,Covey E

更新日期：2000-09-01 00:00:00

abstract：:1. gamma-Aminobutyric acid (GABA) withdrawal syndrome (GWS) represents a particular model of focal epilepsy consecutive to the interruption of a chronic intracortical GABA infusion and is characterized by the appearance of focal epileptic electroencephalographic (EEG) discharges and localized clinical signs on withdra...

journal_title：Journal of neurophysiology

authors： Silva-Barrat C,Araneda S,Menini C,Champagnat J,Naquet R

更新日期：1992-03-01 00:00:00

abstract：:Motor control relies on multiple sources of information. To estimate the position and motion of the hand, the brain uses both vision and body-position (proprioception and kinesthesia) senses from sensors in the muscles, tendons, joints, and skin. Although performance is better when more than one sensory modality is pr...

journal_title：Journal of neurophysiology

authors： Wong T,Henriques DY

更新日期：2009-02-01 00:00:00

abstract：:The sensorimotor calibration of visually guided reaching changes on a trial-to-trial basis in response to random shifts in the visual feedback of the hand. We show that a simple linear dynamical system is sufficient to model the dynamics of this adaptive process. In this model, an internal variable represents the curr...

journal_title：Journal of neurophysiology

authors： Cheng S,Sabes PN

更新日期：2007-04-01 00:00:00

abstract：:The lateral superior olive (LSO) is the primary auditory nucleus for processing of interaural sound level differences, which is one of the major cues for sound localization. During development, survival and maturation of LSO neurons critically depend on synaptic activity and intracellular calcium signaling. Before hea...

journal_title：Journal of neurophysiology

authors： Ene FA,Kalmbach A,Kandler K

更新日期：2007-05-01 00:00:00

abstract：:1. Our previous study showed that two distinct postural modifications occurred when subjects were instructed to step, rather than maintain stance, in response to a backward surface translation: 1) the automatic postural responses to the surfaces perturbation were reduced in magnitude and 2) the anticipatory postural a...

journal_title：Journal of neurophysiology

authors： Burleigh A,Horak F

更新日期：1996-04-01 00:00:00

abstract：:Various forms of synaptic plasticity, including spike timing-dependent plasticity, can be accounted for by calcium-dependent models of synaptic plasticity. However, recent results in which synaptic plasticity is induced by multi-spike protocols cannot simply be accounted for by linear superposition of plasticity due t...

journal_title：Journal of neurophysiology

authors： Cai Y,Gavornik JP,Cooper LN,Yeung LC,Shouval HZ

更新日期：2007-01-01 00:00:00

abstract：:It has been shown that tetanic stimulation of area 2 of the somatosensory cortex produces long-term potentiation in neurons in area 4gamma, and this has been suggested as the basis of learning new motor skills. The purpose of this study was to further elucidate the characteristics of this projection by the use of evok...

journal_title：Journal of neurophysiology

authors： Caria MA,Kaneko T,Kimura A,Asanuma H

更新日期：1997-06-01 00:00:00

abstract：:Glutamate, the neurotransmitter, enhances rapid-eye-movement (REM) sleep when microinjected into the brain stem pedunculopontine tegmentum (PPT) of the cat and rat. Glutamate and its various receptors are normally present in the PPT cholinergic cell compartment. The aim of this study was to identify which specific rec...

journal_title：Journal of neurophysiology

authors： Datta S

更新日期：2002-04-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:We studied the effects of fatigue of the index finger on indices of force variability in discrete and rhythmic accurate force production tasks performed by the index finger and by all four fingers pressing in parallel. An increase in the variance of the force produced by the fatigued index finger was expected. We hypo...

journal_title：Journal of neurophysiology

authors： Singh T,Varadhan SK,Zatsiorsky VM,Latash ML

更新日期：2010-06-01 00:00:00

abstract：:Based on the findings of the preceding paper, it is known that auditory and visual signals have been translated into common coordinates at the level of the superior colliculus (SC) and share a motor circuit involved in the generation of saccadic eye movements. It is not known, however, whether the translation of senso...

journal_title：Journal of neurophysiology

authors： Jay MF,Sparks DL

更新日期：1987-01-01 00:00:00

abstract：:Support-surface movements are commonly used to examine balance control. Subjects typically receive a series of identical or randomly interspersed multidirectional balance perturbations and the atypical "first trial reaction" (evoked by the first perturbation) is often excluded from further analysis. However, this proc...

journal_title：Journal of neurophysiology

authors： Oude Nijhuis LB,Allum JH,Borm GF,Honegger F,Overeem S,Bloem BR

更新日期：2009-06-01 00:00:00

abstract：:Many sensory brain regions are characterized by extensive local network interactions. However, we know relatively little about the contribution of this microcircuitry to sensory coding. Detailed analyses of neuronal microcircuitry are usually performed in vitro, whereas sensory processing is typically studied by recor...

journal_title：Journal of neurophysiology

authors： Ma X,Kohashi T,Carlson BA

更新日期：2013-07-01 00:00:00

abstract：:We have previously shown that control subjects use two distinct temporal strategies when stepping on an inclined surface during walking: one for level and 10 degrees surfaces and another for 20 and 30 degrees surfaces. These two temporal strategies were characterized by systematic shifts in the timing of muscle activi...

journal_title：Journal of neurophysiology

authors： Earhart GM,Bastian AJ

更新日期：2001-02-01 00:00:00

abstract：:Substance P (SP) is an undecapeptide that is co-localized with conventional transmitters in the nucleus accumbens (NAc). Its neurochemical and behavioral effects resemble those of cocaine and amphetamine. How SP accomplishes these effects is not known, partly because its cellular and synaptic effects are not well char...

journal_title：Journal of neurophysiology

authors： Kombian SB,Ananthalakshmi KV,Parvathy SS,Matowe WC

更新日期：2003-02-01 00:00:00