Retinal ganglion neurons express a toxin-resistant developmentally regulated novel type of high-voltage-activated calcium channel.

abstract：:High-frequency oscillatory activity (>200 Hz) termed "fast oscillations" (FO) have been recorded in the rodent somatosensory cortex and may reflect very rapid integration of vibrissal information in sensory cortex. Yet, while electrophysiological correlates suggest that FO is generated within intracortical networks, c...

journal_title：Journal of neurophysiology

authors： Staba RJ,Brett-Green B,Paulsen M,Barth DS

更新日期：2003-05-01 00:00:00

abstract：:The pacemaker current of a bursting neuron of Helix pomatia was investigated using voltage-clamp and pressure-injection techniques. In the steady state the net membrane current was zero near threshold of the action potential at -45 mV. Negative to this potential the membrane current was inward and steady. During burst...

journal_title：Journal of neurophysiology

authors： Swandulla D,Lux HD

更新日期：1985-12-01 00:00:00

abstract：:Single midbrain neurons were examined for effects of ovarian hormone administration on responsiveness to an array of lordosis-controlling types of somatosensory stimuli in anesthetized, ovariectomized Syrian hamsters. Neuronal responses were recorded under four different hormonal treatment conditions: 1) estradiol ben...

journal_title：Journal of neurophysiology

authors： Rose JD,Bieber SL

更新日期：1984-05-01 00:00:00

abstract：:1. We studied the receptive fields of 171 striate cortical neurons from 17 cats raised with binocular lid suture. Of these, 102 fields were within 10 degrees of the area centralis and the remaining 69 were at least 38 degrees from the vertical meridian. 2. Based on their different response properties, cells were divid...

journal_title：Journal of neurophysiology

authors： Watkins DW,Wilson JR,Sherman SM

更新日期：1978-03-01 00:00:00

abstract：:1. We recorded single cell activities in the caudate nucleus of the monkeys trained to perform a series of visuomotor tasks. In the first part of this paper, we summarize the types and locations of neurons in the monkey caudate nucleus. In the second part, we report the characteristics of neurons related to saccadic e...

journal_title：Journal of neurophysiology

authors： Hikosaka O,Sakamoto M,Usui S

更新日期：1989-04-01 00:00:00

abstract：:Normative theories posit that value-based decision-making is context independent. However, decisions between two high-value options can be suboptimally biased by the introduction of a third low-value option. This context-dependent modulation is consistent with the divisive normalization of the value of each stimulus b...

journal_title：Journal of neurophysiology

authors： Itthipuripat S,Cha K,Rangsipat N,Serences JT

更新日期：2015-07-01 00:00:00

abstract：:Proinflammatory cytokines may sensitize primary sensory neurons and facilitate development of neuropathic pain processes after peripheral nerve injury. The goal of this study was to determine whether responses of dorsal root ganglion (DRG) neurons to exogenous tumor necrosis factor alpha (TNF-alpha) are altered in a c...

journal_title：Journal of neurophysiology

authors： Liu B,Li H,Brull SJ,Zhang JM

更新日期：2002-09-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:Retinal Müller cells are highly permeable to potassium as a consequence of their intrinsic membrane properties. Therefore these cells are able to play an important role in maintaining potassium homeostasis in the vertebrate retina during light-induced neuronal activity. Polyamines and other factors present in Müller c...

journal_title：Journal of neurophysiology

authors： Solessio E,Rapp K,Perlman I,Lasater EM

更新日期：2001-04-01 00:00:00

abstract：:Air hunger (uncomfortable urge to breathe) is a component of dyspnea (shortness of breath). Three human H(2)(15)O positron emission tomography (PET) studies have identified activation of phylogenetically ancient structures in limbic and paralimbic regions during dyspnea. Other studies have shown activation of these st...

journal_title：Journal of neurophysiology

authors： Evans KC,Banzett RB,Adams L,McKay L,Frackowiak RS,Corfield DR

更新日期：2002-09-01 00:00:00

abstract：:The whisker region in the rodent primary motor (MI) cortex receives dense projections from neurons aligned with the layer IV septa in the whisker region of the primary somatosensory (SI) cortex. To compare whisker-induced responses in MI with respect to the SI responses in the septa and adjoining barrel regions, we us...

journal_title：Journal of neurophysiology

authors： Chakrabarti S,Zhang M,Alloway KD

更新日期：2008-07-01 00:00:00

abstract：:Peripheral denervation has been shown to cause reorganization of the deafferented somatotopic region in primary somatosensory cortex (S1). However, the basic mechanisms that underlie reorganization are not well understood. In the experiments described in this paper, a novel in vivo/in vitro preparation of adult rat S1...

journal_title：Journal of neurophysiology

authors： Hickmott PW,Merzenich MM

更新日期：2002-09-01 00:00:00

abstract：:Primary auditory cortex (A1) neurons are believed not to carry much information about tonal offsets because A1 neurons in barbiturate-anesthetized animals are usually described as having only onset responses. We investigated tonal offset responses in comparison with onset responses in the caudal part of A1 of awake ca...

journal_title：Journal of neurophysiology

authors： Qin L,Chimoto S,Sakai M,Wang J,Sato Y

更新日期：2007-05-01 00:00:00

abstract：:The effect of a conditioning depolarizing current pulse (80-200 micros) on quantal secretion evoked by a similar test pulse at another site was examined in visualized motor-nerve terminal branches of amphibian endplates (Bufo marinus). Tetrodotoxin (200 nM) and cadmium (50 microM) were used to block voltage-dependent ...

journal_title：Journal of neurophysiology

authors： Macleod GT,Farnell L,Gibson WG,Bennett MR

更新日期：1999-03-01 00:00:00

abstract：:The scratch reflex is a motor task exhibited by the hindlimb of a turtle after complete transection of the spinal cord just posterior to the forelimb enlargement. The scratch is elicited by applying gentle tactile stimulation to a site innervated by spinal segments caudal to the level of the transection. During the sc...

journal_title：Journal of neurophysiology

authors： Mortin LI,Keifer J,Stein PS

更新日期：1985-06-01 00:00:00

abstract：:Despite the peripheral and central immaturities that limit auditory processing in juvenile animals, they are able to lateralize sounds using binaural cues. This study explores a central mechanism that may compensate for these limitations during development. Interaural time and level difference processing by neurons in...

journal_title：Journal of neurophysiology

authors： Green JS,Sanes DH

更新日期：2005-12-01 00:00:00

abstract：:Animals and human beings sense and react to real/potential dangerous stimuli. However, the supraspinal mechanisms relating noxious sensing and nocifensive behavior are mostly unknown. The collateralization and spatial organization of interrelated neurons are important determinants of coordinated network function. Here...

journal_title：Journal of neurophysiology

authors： Leiras R,Martín-Cora F,Velo P,Liste T,Canedo A

更新日期：2016-01-01 00:00:00

abstract：:1. Eye movements were recorded before and after bilateral occipital lobectomy in six rhesus monkeys trained to fixate and to follow small targets. Striate cortex was completely removed in two animals; small islands islands remained in the others. In all animals portions of extrastriate cortex were also removed but the...

journal_title：Journal of neurophysiology

authors： Zee DS,Tusa RJ,Herdman SJ,Butler PH,Gücer G

更新日期：1987-10-01 00:00:00

abstract：:1. In this study we have tested the hypothesis that the mechanisms controlling stabilization of the head-neck motor system can vary with both the frequency and spatial orientation of an externally applied perturbation. Angular velocity of the head with respect to the trunk (neck) and myoelectric activity of two neck m...

journal_title：Journal of neurophysiology

authors： Keshner EA,Cromwell RL,Peterson BW

更新日期：1995-06-01 00:00:00

abstract：:In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

journal_title：Journal of neurophysiology

authors： Greenberg I,Manor Y

更新日期：2005-02-01 00:00:00

abstract：:The functional role of sensory input to the motor cortex was studied by interrupting two major input pathways. One was the dorsal column, which sends the input directly through the thalamus to the motor cortex, and the other was the sensory cortex, which transfers its input through association fibers. Removal of the s...

journal_title：Journal of neurophysiology

authors： Asanuma H,Arissian K

更新日期：1984-08-01 00:00:00

abstract：:1. Compartmental modeling experiments were carried out in an anatomically characterized neocortical pyramidal cell to study the integrative behavior of a complex dendritic tree containing active membrane mechanisms. Building on a previously presented hypothesis, this work provides further support for a novel principle...

journal_title：Journal of neurophysiology

authors： Mel BW

更新日期：1993-09-01 00:00:00

abstract：:Intrathecally applied nicotine reduces bradykinin-induced plasma extravasation (BK-induced PE) in the rat knee joint. This depression is mediated by the hypothalamo-pituitary-adrenal (HPA) axis and is enhanced by interruption of impulse traffic in afferents of the abdominal vagus nerve. Like intrathecal nicotine, elec...

journal_title：Journal of neurophysiology

authors： Miao FJ,Jänig W,Green PG,Levine JD

更新日期：1997-09-01 00:00:00

abstract：:Despite the well-established contribution of neurohumoral activation to morbidity and mortality in heart failure (HF) patients, relatively little is known about the underlying central nervous system mechanisms. In this study, we aimed to determine whether changes in GABAergic inhibitory and glutamatergic excitatory sy...

journal_title：Journal of neurophysiology

authors： Potapenko ES,Biancardi VC,Florschutz RM,Ryu PD,Stern JE

更新日期：2011-09-01 00:00:00

abstract：:1. Rat dorsal root ganglion (DRG) cell bodies were screened according to action potential (AP) duration, capsaicin sensitivity, expression of IH, IA, and N-, L-, and T-type Ca2+ channel currents. AP duration was measured at half of total amplitude at a membrane potential of -60 mV. Sensitivity to capsaicin was defined...

journal_title：Journal of neurophysiology

authors： Cardenas CG,Del Mar LP,Scroggs RS

更新日期：1995-11-01 00:00:00

abstract：:Reaching movements are subject to noise associated with planning and execution, but precisely how these noise sources interact to determine patterns of endpoint variability in three-dimensional space is not well understood. For frontal plane movements, variability is largest along the depth axis (the axis along which ...

journal_title：Journal of neurophysiology

authors： Apker GA,Buneo CA

更新日期：2012-01-01 00:00:00

abstract：:1. Single motor axons innervating human toe extensor muscles were selectively stimulated through a tungsten microelectrode inserted percutaneously into the peroneal nerve. Twitch and tetanic forces were measured from a strain gauge over the proximal phalanx of the toe generating the greatest force. Twitch data were ob...

journal_title：Journal of neurophysiology

authors： Macefield VG,Fuglevand AJ,Bigland-Ritchie B

更新日期：1996-06-01 00:00:00

abstract：:Evidence first described in reduced animal models over 100 years ago led to deductions about the control of locomotion through spinal locomotor central pattern-generating (CPG) networks. These discoveries in nature were contemporaneous with another form of deductive reasoning found in popular culture, that of Arthur C...

journal_title：Journal of neurophysiology

authors： Klarner T,Zehr EP

更新日期：2018-07-01 00:00:00

abstract：:Manipulations of vagal activity are used to treat medical pathologies, but the underlying CNS changes caused by these treatments are not well understood. Furthermore, heart and lung transplant as well as treatments for many gastrointestinal disorders result in section of the vagus nerve (vagotomy). Following unilatera...

journal_title：Journal of neurophysiology

authors： Swartz JB,Weinreich D

更新日期：2009-11-01 00:00:00

abstract：:Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding mult...

journal_title：Journal of neurophysiology

authors： Dykes RW,Landry P,Metherate R,Hicks TP

更新日期：1984-12-01 00:00:00