Activity in the human superior colliculus relating to endogenous saccade preparation and execution.

abstract：:Postembryonic developmental changes in electrophysiological properties of the AIY interneuron class were investigated using whole cell voltage clamp. AIY interneurons displayed an increase in cell capacitance during larval development, whereas steady-state current amplitude did not increase. The time course of the out...

journal_title：Journal of neurophysiology

authors： Faumont S,Boulin T,Hobert O,Lockery SR

更新日期：2006-06-01 00:00:00

abstract：:Systemic exposure to N-methyl-d-aspartate (NMDA) receptor antagonists can lead to psychosis and prefrontal cortex (PFC)-dependent behavioral impairments. Agonists of metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate the adverse behavioral effects of NMDA antagonists in humans and laboratory animals, and are be...

journal_title：Journal of neurophysiology

authors： Homayoun H,Jackson ME,Moghaddam B

更新日期：2005-04-01 00:00:00

abstract：:Previously, an essential tremor-like phenotype has been noted in animals with a global knockout of the GABAAα1 subunit. Given the hypothesized role of the cerebellum in tremor, including essential tremor, we used transgenic mice to selectively knock out the GABAAα1 subunit from cerebellar Purkinje cells. We examined t...

journal_title：Journal of neurophysiology

authors： Nietz A,Krook-Magnuson C,Gutierrez H,Klein J,Sauve C,Hoff I,Christenson Wick Z,Krook-Magnuson E

更新日期：2020-10-01 00:00:00

abstract：:Recent discoveries of visceral nociceptive inputs sharing the classical tactile pathway in the dorsal-column medial lemniscus system have opened a new venue for the investigation of somatovisceral interactions. The current study was designed to determine whether somatic innocuous inputs modulate visceral nociceptive t...

journal_title：Journal of neurophysiology

authors： Zhang HQ,Al-Chaer ED,Willis WD

更新日期：2002-09-01 00:00:00

abstract：:Vestibuloocular reflex performance and adaptation were examined during vestibulocerebellar inactivation by localized lidocaine microdialysis or injection in goldfish. In the light, eye velocity perfectly compensated for head velocity (Vis-VOR) during sinusoidal yaw rotation (1/8 Hz +/- 20 degrees). In the dark, the re...

journal_title：Journal of neurophysiology

authors： McElligott JG,Beeton P,Polk J

更新日期：1998-03-01 00:00:00

abstract：:In sensory systems, the thalamus has historically been considered a relay station. Neural representations of temporal modulations in the auditory system undergo considerable changes as they pass from the inferior colliculus (IC) to the auditory cortex. We sought to determine in awake primates the extent to which audit...

journal_title：Journal of neurophysiology

authors： Bartlett EL,Wang X

更新日期：2007-02-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:Previous studies have shown that daily, moderate-level sound exposure, or conditioning, can reduce injury from a subsequent high-level noise exposure. We tested the hypothesis that this conditioning produces an increased activity in the olivocochlear efferent reflex, a reflex known to provide protection to the cochlea...

journal_title：Journal of neurophysiology

authors： Brown MC,Kujawa SG,Liberman MC

更新日期：1998-06-01 00:00:00

abstract：:Combined transcranial magnetic stimulation and electroencephalography (TMS-EEG) enables noninvasive neurophysiological investigation of the human cortex. A TMS paradigm of short-latency afferent inhibition (SAI) is characterized by attenuation of the motor-evoked potential (MEP) and modulation of N100 of the TMS-evoke...

journal_title：Journal of neurophysiology

authors： Noda Y,Cash RF,Zomorrodi R,Dominguez LG,Farzan F,Rajji TK,Barr MS,Chen R,Daskalakis ZJ,Blumberger DM

更新日期：2016-09-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:Unitary excitatory (EPSP) and inhibitory (IPSP) postsynaptic potentials (PSPs) were evoked between neurons in Rexed's laminae (L)II-V of spinal slices from young hamsters (7-24 days old) at 27°C using paired whole cell recordings. Laminar differences in synaptic efficacy were observed: excitatory connections were more...

journal_title：Journal of neurophysiology

authors： Zhang W,Schneider SP

更新日期：2011-06-01 00:00:00

abstract：:Neurons of the avian nucleus laminaris (NL) compute the interaural time difference (ITD) by detecting coincident arrivals of binaural signals with submillisecond accuracy. The cellular mechanisms for this temporal precision have long been studied theoretically and experimentally. The myelinated axon initial segment in...

journal_title：Journal of neurophysiology

authors： Ashida G,Abe K,Funabiki K,Konishi M

更新日期：2007-03-01 00:00:00

abstract：:The blood oxygen level-dependent (BOLD) functional magnetic resonance imaging signal arises as a consequence of changes in blood flow and oxygen usage that in turn are modulated by changes in neural activity. Much attention has been given to both theoretical and experimental aspects of the energetics but not to the ne...

journal_title：Journal of neurophysiology

authors： Bennett MR,Farnell L,Gibson WG

更新日期：2018-03-01 00:00:00

abstract：:We studied the effects of fatigue of the index finger on indices of force variability in discrete and rhythmic accurate force production tasks performed by the index finger and by all four fingers pressing in parallel. An increase in the variance of the force produced by the fatigued index finger was expected. We hypo...

journal_title：Journal of neurophysiology

authors： Singh T,Varadhan SK,Zatsiorsky VM,Latash ML

更新日期：2010-06-01 00:00:00

abstract：:Frequency facilitation is a process whereby neurosecretion increases as a function of stimulation frequency during repetitive synaptic activity. To examine the physiological basis underlying facilitation, we have estimated the frequency dependence of the synaptic parameters n (number of units capable of responding to ...

journal_title：Journal of neurophysiology

authors： Worden MK,Bykhovskaia M,Hackett JT

更新日期：1997-07-01 00:00:00

abstract：:The vestibuloocular reflex (VOR) needs to modulate its gain depending on target distance to prevent retinal slip during head movements. We investigated gain modulation (context compensation) for binocular gaze stabilization in human subjects during voluntary yaw and pitch head rotations. Movements of each eye were rec...

journal_title：Journal of neurophysiology

authors： Medendorp WP,Van Gisbergen JA,Van Pelt S,Gielen CC

更新日期：2000-12-01 00:00:00

abstract：:In big brown bats, tone-specific plastic changes [best frequency (BF) shifts] of cortical and collicular neurons can be evoked by auditory fear conditioning, repetitive acoustic stimuli or cortical electric stimulation. It has been shown that acetylcholine (ACh) plays an important role in evoking large long-term corti...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N,Gao E

更新日期：2005-08-01 00:00:00

abstract：:Intracellular recording from lumbar motoneurons and extracellular recording from ventral roots of the neonatal rat isolated spinal cord were used to study the mechanisms responsible for the excitation mediated by NK3 tachykinin receptors. The selective NK3 agonists senktide or [MePhe7]neurokinin B induced a slow depol...

journal_title：Journal of neurophysiology

authors： Marchetti C,Nistri A

更新日期：2001-12-01 00:00:00

abstract：:Activation of muscarinic receptors and GABA(B) receptors causes presynaptic inhibition of glutamatergic synaptic potentials at excitatory feedback connections in cortical structures. These effects may regulate dynamics in cortical structures, with presynaptic inhibition allowing extrinsic afferent input to dominate du...

journal_title：Journal of neurophysiology

authors： Hasselmo ME,Fehlau BP

更新日期：2001-10-01 00:00:00

abstract：:A growing body of evidence suggests that decision-making and action execution are governed by partly overlapping operating principles. Especially, previous work proposed that a shared decision urgency/movement vigor signal, possibly computed in the basal ganglia, coordinates both deliberation and movement durations in...

journal_title：Journal of neurophysiology

authors： Reynaud AJ,Saleri Lunazzi C,Thura D

更新日期：2020-08-01 00:00:00

abstract：:Top-down selective attention to the affective properties of taste stimuli increases activation to the taste stimuli in the orbitofrontal cortex (OFC) and pregenual cingulate cortex (PGC), and selective attention to the intensity of the stimuli increases the activation in the insular taste cortex, but the origin of the...

journal_title：Journal of neurophysiology

authors： Grabenhorst F,Rolls ET

更新日期：2010-09-01 00:00:00

abstract：:1. Responses of complex cells in cat striate cortex were studied with flashed light slit stimuli. The responses to slits flashed in different positions in the receptive field were assessed quantitatively before and after periods of prolonged stimulation of one small region of the receptive field. This type of prolonge...

journal_title：Journal of neurophysiology

authors： Marlin S,Douglas R,Cynader M

更新日期：1993-06-01 00:00:00

abstract：:Cholinergic signaling coupled to sensory-driven neuronal depolarization is essential for modulating lasting changes in deep-layer neural excitability and experience-dependent plasticity in the primary auditory cortex. However, the underlying cellular mechanism(s) associated with coincident cholinergic receptor activat...

journal_title：Journal of neurophysiology

authors： Fu X,Ye H,Jia H,Wang X,Chomiak T,Luo F

更新日期：2019-12-01 00:00:00

abstract：:1. Recent immunocytochemical and receptor binding data have demonstrated a transient somatotopic patterning of serotonin (5-HT)-immunoreactive fibers in the primary somatosensory cortex of developing rats and a transient expression of 5-HT1B receptors on thalamocortical axons from the ventral posteromedial thalamic nu...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Bennett-Clarke CA,Shi MY,Mooney RD

更新日期：1994-11-01 00:00:00

abstract：:1. Single-unit and multiunit activities were recorded at the area 17-18 border of each cortical hemisphere in paralyzed cats anesthetized with nitrous oxide supplemented with halothane. Cross-correlation histograms (CCHs) were computed between 86 pairs of single units and 99 pairs of multiunit activities. Visually evo...

journal_title：Journal of neurophysiology

authors： Nowak LG,Munk MH,Nelson JI,James AC,Bullier J

更新日期：1995-12-01 00:00:00

abstract：:It is shown that the primate primary taste cortex represents not only taste but also information about many nontaste properties of oral stimuli. Of 1,122 macaque anterior insular/frontal opercular neurons recorded, 62 (5.5%) responded to oral stimuli. Of the orally responsive neurons, some (53%) represented the viscos...

journal_title：Journal of neurophysiology

authors： Verhagen JV,Kadohisa M,Rolls ET

更新日期：2004-09-01 00:00:00

abstract：:The general objectives of our research, presented in this series of papers, were to develop a computational model of the brain stem respiratory neural network and to explore possible neural mechanisms that provide the genesis of respiratory oscillations and the specific firing patterns of respiratory neurons. The pres...

journal_title：Journal of neurophysiology

authors： Rybak IA,Paton JF,Schwaber JS

更新日期：1997-04-01 00:00:00

abstract：:In humans, functional magnetic resonance imaging (fMRI) activity in the anterior cingulate cortex (ACC) and the nucleus accumbens (NAc) appears to reflect affective and motivational aspects of pain. The responses of this reward-aversion circuit to relief of pain, however, have not been investigated in detail. Moreover...

journal_title：Journal of neurophysiology

authors： Becerra L,Navratilova E,Porreca F,Borsook D

更新日期：2013-09-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:The mechanisms behind the therapeutic effects of electrical stimulation of the brain in epilepsy and other disorders are poorly understood. Previous studies in vitro have shown that uniform electric fields can suppress epileptiform activity through a direct polarizing effect on neuronal membranes. Such an effect depen...

journal_title：Journal of neurophysiology

authors： Mikkelsen R,Andreasen M,Nedergaard S

更新日期：2013-06-01 00:00:00