Selective loss of the GABAAα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype.

abstract：:We perceive objects as permanent and stable despite frequent occlusions and eye movements, but their representation in the visual cortex is neither permanent nor stable. Feature selective cells respond only as long as objects are visible, and their responses depend on eye position. We explored the hypothesis that the ...

journal_title：Journal of neurophysiology

authors： Zhu SD,Zhang LA,von der Heydt R

更新日期：2020-05-01 00:00:00

abstract：:Macaque SEF neurons encode object-centered directions of eye movements regardless of the visual attributes of instructional cues. Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit object-centered direction selectivity in the context of a task in which a spot flashed on the right or left end of...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN

更新日期：1999-05-01 00:00:00

abstract：:Rhythm generation by the gastric motor network in the stomatogastric ganglion (STG) of the lobster Homarus gammarus is controlled by modulatory projection neurons from rostral commissural ganglia (CoGs); blocking action potential conduction in these inputs to the STG of a stomatogastric nervous system in vitro rapidly...

journal_title：Journal of neurophysiology

authors： Faumont S,Simmers J,Meyrand P

更新日期：1998-11-01 00:00:00

abstract：:This study reexamined the perceptual equivalence of active and passive touch using a computer-controlled force-feedback device. Nine subjects explored a 6 x 10-cm workspace, with the index finger resting on a mobile flat plate, and experienced simulated Gaussian ridges and troughs (width, 15 mm; amplitude, 0.5 to 4.5 ...

journal_title：Journal of neurophysiology

authors： Smith AM,Chapman CE,Donati F,Fortier-Poisson P,Hayward V

更新日期：2009-12-01 00:00:00

abstract：:1. The properties of parietal neurons were studied in four adult rhesus monkeys during fast arm movements. The animals were trained to perform flexion or extension of the forearm about the elbow in response to specific auditory cues. Single neuron activity was recorded in 272 area 5 neurons, 81 neurons of the somatose...

journal_title：Journal of neurophysiology

authors： Burbaud P,Doegle C,Gross C,Bioulac B

更新日期：1991-08-01 00:00:00

abstract：:1. The role of the structures of the outer ear in producing monaural and binaural spectral cues to sound location was examined acoustically in the ferret. A probe microphone was introduced across the wall of the external auditory canal and its responses to digitally constructed wideband signals were recorded for a lar...

journal_title：Journal of neurophysiology

authors： Carlile S,King AJ

更新日期：1994-02-01 00:00:00

abstract：:1. Compartmental models were used to compute the time constants and coefficients of voltage and current transients in hypothetical neurons having tapering dendrites or soma shunt and in a serially reconstructed motoneuron with soma shunt. These time constants and coefficients were used in equivalent cylinder formulas ...

journal_title：Journal of neurophysiology

authors： Holmes WR,Rall W

更新日期：1992-10-01 00:00:00

abstract：:In this study, the juxtamembrane region of the Drosophila SNARE protein neuronal-Synaptobrevin (n-Syb) was tested for its role in synaptic transmission. A transgenic approach was used to express n-Syb mutant genes. The transgenes carried engineered point mutations that alter the amino acid sequence of the conserved tr...

journal_title：Journal of neurophysiology

authors： DeMill CM,Qiu X,Kisiel M,Bolotta A,Stewart BA

更新日期：2014-09-15 00:00:00

abstract：:Electrically excitable cells have voltage-dependent ion channels on the plasma membrane that regulate membrane permeability to specific ions. Voltage-gated Ca(2+) channels (VGCCs) are especially important as Ca(2+) serves as both a charge carrier and second messenger. Zebrafish (Danio rerio) are an important model ver...

journal_title：Journal of neurophysiology

authors： Won YJ,Ono F,Ikeda SR

更新日期：2011-01-01 00:00:00

abstract：:The cerebellum of the mormyrid fish consists of three major divisions: the valvula, the central lobes, and the caudal lobes. Several studies have focused on the central lobes and the valvula, but little is known about the caudal lobes. The mormyrid caudal lobe includes anterior and posterior components. The anterior c...

journal_title：Journal of neurophysiology

authors： Zhang Y,Han VZ

更新日期：2007-09-01 00:00:00

abstract：:Fast-spiking (FS) interneurons provide the main route of feedforward inhibition from cortex to spiny projection neurons in the striatum. A steep current-firing frequency curve and a dense local axonal arbor suggest that even small excitatory inputs could translate into powerful feedforward inhibition, although such an...

journal_title：Journal of neurophysiology

authors： Kotaleski JH,Plenz D,Blackwell KT

更新日期：2006-01-01 00:00:00

abstract：:The possibility of using randomly generated stimulus intervals (with a Poisson distribution) to identify the type(s) of intrafusal fiber activated by the stimulation of single static gamma axons was tested in Peroneus tertius muscle spindles of anesthetized cats. Three patterns of random stimulation with different val...

journal_title：Journal of neurophysiology

authors： Petit J,Banks RW,Laporte Y

更新日期：1999-06-01 00:00:00

abstract：:Several recent studies have shown that extracting pattern motion direction is a dynamical process where edge motion is first extracted and pattern-related information is encoded with a small time lag by MT neurons. A similar dynamics was found for human reflexive or voluntary tracking. Here, we bring an essential, but...

journal_title：Journal of neurophysiology

authors： Barthélemy FV,Fleuriet J,Masson GS

更新日期：2010-03-01 00:00:00

abstract：:Cutaneous reflexes evoked in the muscles of the arms with electrical stimulation of nerves of the foot ("interlimb reflexes") are observed during walking. These reflexes have been suggested to coordinate the actions of the legs and arms when walking is disturbed. Recently, we showed that cutaneous reflexes evoked in t...

journal_title：Journal of neurophysiology

authors： Haridas C,Zehr EP,Misiaszek JE

更新日期：2006-12-01 00:00:00

abstract：:Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...

journal_title：Journal of neurophysiology

authors： Long J,Tazoe T,Soteropoulos DS,Perez MA

更新日期：2016-03-01 00:00:00

abstract：:The exercise pressor reflex (EPR) is generated by group III and IV muscle afferents during exercise to increase cardiovascular function. Muscle contraction is triggered by ACh, which is metabolized into choline that could serve as a signal of exercise-induced activity. We demonstrate that ACh can induce current in mus...

journal_title：Journal of neurophysiology

authors： Baxter JC,Ramachandra R,Mayne DR,Elmslie KS

更新日期：2014-09-15 00:00:00

abstract：:Norepinephrine (NE) is a potent modulator of breathing that can increase/decrease respiratory activity by α1-/α2-adrenergic receptor (AR) activation, respectively. The retrotrapezoid nucleus (RTN) is known to contribute to central chemoreception, inspiration, and active expiration. Here we investigate the sources of c...

journal_title：Journal of neurophysiology

authors： Oliveira LM,Moreira TS,Kuo FS,Mulkey DK,Takakura AC

更新日期：2016-09-01 00:00:00

abstract：:Activation of muscarinic receptors and GABA(B) receptors causes presynaptic inhibition of glutamatergic synaptic potentials at excitatory feedback connections in cortical structures. These effects may regulate dynamics in cortical structures, with presynaptic inhibition allowing extrinsic afferent input to dominate du...

journal_title：Journal of neurophysiology

authors： Hasselmo ME,Fehlau BP

更新日期：2001-10-01 00:00:00

abstract：:Systemic exposure to N-methyl-d-aspartate (NMDA) receptor antagonists can lead to psychosis and prefrontal cortex (PFC)-dependent behavioral impairments. Agonists of metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate the adverse behavioral effects of NMDA antagonists in humans and laboratory animals, and are be...

journal_title：Journal of neurophysiology

authors： Homayoun H,Jackson ME,Moghaddam B

更新日期：2005-04-01 00:00:00

abstract：:The neuromodulator acetylcholine (ACh) shapes neocortical function during sensory perception, motor control, arousal, attention, learning, and memory. Here we investigate the mechanisms by which ACh affects neocortical pyramidal neurons in adult mice. Stimulation of cholinergic axons activated muscarinic and nicotinic...

journal_title：Journal of neurophysiology

authors： Hedrick T,Waters J

更新日期：2015-04-01 00:00:00

abstract：:The acid-sensing ion channels (ASICs) form cation channels that are transiently activated by extracellular protons. They are expressed in dorsal root ganglia (DRG) neurons and in the periphery where they play a function in nociception and mechanosensation. Previous studies showed that FMRFamide and related peptides po...

journal_title：Journal of neurophysiology

authors： Xie J,Price MP,Wemmie JA,Askwith CC,Welsh MJ

更新日期：2003-05-01 00:00:00

abstract：:This study aimed to determine whether individuals with spastic diplegic cerebral palsy (SDCP) have deficits in anticipatory inhibition of postural muscle activity. Nine individuals with SDCP (SDCP group, 3 female and 6 male, 13-24 yr of age) and nine age- and sex-matched individuals without disability (control group) ...

journal_title：Journal of neurophysiology

authors： Tomita H,Fukaya Y,Totsuka K,Tsukahara Y

更新日期：2013-04-01 00:00:00

abstract：:Rats can readily be trained to jump a gap of around 16 cm in the dark and a considerably larger gap in the light for a food reward. In the light, they use vision to estimate the distance to be jumped. In the dark, they use their vibrissae at the farthest distances. Bilateral whisker shaving or barrel field lesions red...

journal_title：Journal of neurophysiology

authors： Jenkinson EW,Glickstein M

更新日期：2000-10-01 00:00:00

abstract：:A stratified organization of visual, somatic and acoustic representations was observed in the cat SC. Cells of the superficial laminae were exclusively visual. Visual, somatic, and acoustic cells were observed in the intermediate laminae while the deeper laminae were predominantly nonvisual. A detailed examination of ...

journal_title：Journal of neurophysiology

authors： Stein BE,Magalhães-Castro B,Kruger L

更新日期：1976-03-01 00:00:00

abstract：:Glycinergic and GABAergic inhibition are juxtaposed at one retinal synaptic layer yet likely perform different functions. These functions have usually been evaluated using receptor antagonists. In examining retinal glycine receptors, we were surprised to find that commonly used concentrations of GABA antagonists block...

journal_title：Journal of neurophysiology

authors： Wang P,Slaughter MM

更新日期：2005-06-01 00:00:00

abstract：:A quantitative analysis of activity-related calcium dynamics was performed in motoneurons of the nucleus hypoglossus in the brain stem slice preparation from mouse by simultaneous patch-clamp and microfluorometric calcium measurements. Motoneurons were analyzed under in vitro conditions that kept them in a functionall...

journal_title：Journal of neurophysiology

authors： Lips MB,Keller BU

更新日期：1999-12-01 00:00:00

abstract：:We examined the influence of focal cerebellar lesions on working memory (n-back task), gait, and the interaction between working memory and different gait tasks in a dual-task paradigm. The analysis included 17 young patients with chronic focal lesions after cerebellar tumor resection and 17 age-matched controls. Pati...

journal_title：Journal of neurophysiology

authors： Ilg W,Christensen A,Mueller OM,Goericke SL,Giese MA,Timmann D

更新日期：2013-11-01 00:00:00

abstract：:We have characterized selectivity and sparseness in anterior inferotemporal cortex, using a large data set. Responses were collected from 674 monkey inferotemporal cells, each stimulated by 806 object photographs. This 806 × 674 matrix was examined in two ways: columnwise, looking at responses of a single neuron to al...

journal_title：Journal of neurophysiology

authors： Lehky SR,Kiani R,Esteky H,Tanaka K

更新日期：2011-09-01 00:00:00

abstract：:To investigate the nature of the visuomotor transformation, previous studies have used pointing tasks and examined how adaptation to a spatially localized mismatch between vision and proprioception generalizes across the workspace. Whereas some studies found extensive spatial generalization of single-point remapping, ...

journal_title：Journal of neurophysiology

authors： Malfait N,Henriques DY,Gribble PL

更新日期：2008-01-01 00:00:00

abstract：:Paw-shake responses (PSRs) were evoked by wrapping masking tape around the hind-paw in nine cats spinalized at the T12 level either at 2 or 12 wk of age or as young adults (10-12 mo). Electromyographic responses of ankle extensors (LG and SOL) and one ankle flexor (TA) were recorded through the 6th mo after cord trans...

journal_title：Journal of neurophysiology

authors： Sabin C,Smith JL

更新日期：1984-04-01 00:00:00