Developmental regulation of whole cell capacitance and membrane current in identified interneurons in C. elegans.

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:1. We studied the effect of zinc on the gamma-aminobutyric acid-C (GABAC) receptor in acutely isolated catfish cone horizontal cells using the whole cell patch-clamp technique. 2. GABA activates the GABAC receptor with a half-activation concentration (EC50) of 2.99 microM. The Hill coefficient is 1.32. Desensitization...

journal_title：Journal of neurophysiology

authors： Dong CJ,Werblin FS

更新日期：1995-02-01 00:00:00

abstract：:1. In a search for correlated fast rhythms in recurrent laryngeal (RL) expiratory (E) activities, we performed spectral and coherence analysis on bilateral RL nerve discharges in 54 midcollicular decerebrate, paralyzed cats. 2. Inspiratory (I) RL activities showed in almost all cases high-frequency oscillations (HFO, ...

journal_title：Journal of neurophysiology

authors： Huang WX,Christakos CN,Cohen MI,He Q

更新日期：1993-11-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:Ifenprodil is a selective blocker of NMDA receptors that are heterodimers composed of GluN1/GluN2B subunits. This pharmacological profile has been extensively used to test the role of GluN2B-containing NMDA receptors in learning and memory formation. However, ifenprodil has also been reported to have actions at a numb...

journal_title：Journal of neurophysiology

authors： Delaney AJ,Power JM,Sah P

更新日期：2012-03-01 00:00:00

abstract：:When they are 1-2 mo old, domesticated Mongolian gerbils begin having initially mild seizures which become more severe with age. To evaluate the development of this increasing seizure severity, we obtained field potential responses of the dentate gyrus to paired-pulse stimulation of the perforant path during seizures....

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Wong EH

更新日期：2002-08-01 00:00:00

abstract：:1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied...

journal_title：Journal of neurophysiology

authors： Breakwell NA,Rowan MJ,Anwyl R

更新日期：1996-11-01 00:00:00

abstract：:1. The hyperpolarization that follows tetanic stimulation was recorded intra-axonally from the internodal region of intramuscular myelinated motor axons. 2. The peak amplitude of the posttetanic hyperpolarization (PTH) that followed stimulation at 20-100 Hz for < or = 35 s increased with increasing train duration, rea...

journal_title：Journal of neurophysiology

authors： Morita K,David G,Barrett JN,Barrett EF

更新日期：1993-11-01 00:00:00

abstract：:Persistent spiking in response to a discrete stimulus is considered to reflect the active maintenance of a memory for that stimulus until a behavioral response is made. This response pattern has been reported in learning paradigms that impose a temporal gap between stimulus presentation and behavioral response, includ...

journal_title：Journal of neurophysiology

authors： Siegel JJ

更新日期：2014-11-01 00:00:00

abstract：:Substance P (SP) hyperpolarizes approximately 80% of ferret vagal sensory neurons (nodose ganglion neurons) via NK-1 receptor-mediated activation of a potassium current (IK). A depolarizing current activated by membrane hyperpolarization could minimize the SP-induced hyperpolarization. Such a current exists in 65% of ...

journal_title：Journal of neurophysiology

authors： Jafri MS,Weinreich D

更新日期：1998-02-01 00:00:00

abstract：:Active sensing in biological system consists of emitting/receiving a periodic signal to explore the environment. The signal can be emitted toward distant objects, as in echolocation, or in direct contact with the object, for example, whisking in rodents. We explored the hypothesis that a similar mechanism exists in hu...

journal_title：Journal of neurophysiology

authors： Dione M,Wessberg J

更新日期：2019-09-01 00:00:00

abstract：:1. Hair cells in whole-mount in vitro preparations of the utricular macula of the bullfrog (Rana catesbeiana) were selected according to their macular location and hair bundle morphology. The voltage responses of selected hair cells to intracellular current steps and sinusoids in the frequency range of 0.5-200 Hz were...

journal_title：Journal of neurophysiology

authors： Baird RA

更新日期：1994-02-01 00:00:00

abstract：:1. Teased axon recordings were made from 167 spontaneously active A beta- and A delta-afferents that ended in sciatic nerve end neuromas of 6-12 days standing. When challenged with a standard bolus of systemically applied adrenaline, 100 (60%) responded, either with an increase in baseline firing frequency (excitation...

journal_title：Journal of neurophysiology

authors： Chen Y,Michaelis M,Janig W,Devor M

更新日期：1996-12-01 00:00:00

abstract：:The aim of the study was to examine whether the sustained increases in the excitability of afferent fibers traversing the dorsal columns evoked by their polarization depend on the branching points of these fibers. To this end, the effects of epidural polarization were compared in four spinal regions in deeply anesthet...

journal_title：Journal of neurophysiology

authors： Li Y,Hari K,Lucas-Osma AM,Fenrich KK,Bennett DJ,Hammar I,Jankowska E

更新日期：2020-07-01 00:00:00

abstract：:High-frequency stimulation (HFS) is used to treat a variety of neurological diseases, yet its underlying therapeutic action is not fully elucidated. Previously, we reported that HFS-induced elevation in [K(+)](e) or bath perfusion of raised K(e)(+) depressed rat entopeduncular nucleus (EP) neuronal activity via an enh...

journal_title：Journal of neurophysiology

authors： Shin DS,Carlen PL

更新日期：2008-05-01 00:00:00

abstract：:The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exp...

journal_title：Journal of neurophysiology

authors： Xu J,Yu L,Stanford TR,Rowland BA,Stein BE

更新日期：2015-02-01 00:00:00

abstract：:1. The sensory responsiveness of cells in the inferior olive is known to be suppressed during certain phases of active movement. These experiments were designed to test the possibility that activity in the rubrospinal pathway contributes to this suppression. We recorded from cells sensitive to light touch located in o...

journal_title：Journal of neurophysiology

authors： Weiss C,Houk JC,Gibson AR

更新日期：1990-10-01 00:00:00

abstract：:There are at least two respiration-related rhythm generators in the medulla: the pre-Bötzinger complex, which produces inspiratory (Insp) neuron bursts, and the parafacial respiratory group (pFRG), which produces predominantly preinspiratory (Pre-I) neuron bursts. The pFRG Pre-I neuron activity has not been correlated...

journal_title：Journal of neurophysiology

authors： Onimaru H,Kumagawa Y,Homma I

更新日期：2006-07-01 00:00:00

abstract：:The caudal primate prefrontal cortex (PFC) is involved in target selection and visually guided saccades through both covert attention and overt orienting eye movements. Unilateral damage to the caudal PFC often leads to decreased awareness of a contralesional target alone, referred to as "neglect," or when it is prese...

journal_title：Journal of neurophysiology

authors： Adam R,Johnston K,Everling S

更新日期：2019-08-01 00:00:00

abstract：:In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

journal_title：Journal of neurophysiology

authors： Greenberg I,Manor Y

更新日期：2005-02-01 00:00:00

abstract：:The present series of investigations was aimed to disclose the possible sites of action of excitatory and inhibitory inputs on tho-interneuron pathway mediating the primary afferent depolarization (PAD) of group I afferents of extensor muscles in the cat spinal cord. To this end we compared the effects produced by sti...

journal_title：Journal of neurophysiology

authors： Rudomín P,Jiménez I,Solodkin M,Dueñas S

更新日期：1983-10-01 00:00:00

abstract：:1. During alertness, lemniscal thalamocortical neurons in the ventral medial geniculate body (MGBv) encode sound signals by firing action potentials in a tonic mode. When they are in a burst firing mode, characteristic of thalamic neurons during some sleep states, the same stimuli may have an alerting function, leadin...

journal_title：Journal of neurophysiology

authors： Tennigkeit F,Schwarz DW,Puil E

更新日期：1996-12-01 00:00:00

abstract：:The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...

journal_title：Journal of neurophysiology

authors： White-Schwoch T,Anderson S,Krizman J,Nicol T,Kraus N

更新日期：2019-08-01 00:00:00

abstract：:The location of the human nociceptive area(s) near the Sylvian fissure is still controversial in spite of evidence from imaging and evoked potential studies that noxious heat stimuli activate somatosensory areas in that region. Some studies have suggested the secondary somatosensory cortex (SII) on the upper bank of t...

journal_title：Journal of neurophysiology

authors： Vogel H,Port JD,Lenz FA,Solaiyappan M,Krauss G,Treede RD

更新日期：2003-06-01 00:00:00

abstract：:The ability to adjust the amplitude of gaze shifts in response to persistent visual errors ("gaze adaptation") has been investigated primarily by introducing visual errors at the end of saccades produced by head-restrained primates. Very little is known about the behavior and neural mechanisms underlying gaze adaptati...

journal_title：Journal of neurophysiology

authors： Cecala AL,Freedman EG

更新日期：2009-01-01 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can produce a lasting polarity-specific modulation of cortical excitability in the brain, and it is increasingly used in experimental and clinical settings. Recent studies suggest that the after-effects of tDCS are related to molecular mechanisms of activity-dependent syn...

journal_title：Journal of neurophysiology

authors： Ranieri F,Podda MV,Riccardi E,Frisullo G,Dileone M,Profice P,Pilato F,Di Lazzaro V,Grassi C

更新日期：2012-04-01 00:00:00

abstract：:A powerful early inhibition is seen in triceps surae after transcutaneous electrical stimulation of the Achilles tendon [tendon electrical stimulation (TES)]. The aim of the present study was to confirm results from surface electromyogram (SEMG) recordings that the inhibition is not wholly or partly due to stimulation...

journal_title：Journal of neurophysiology

authors： Rogasch NC,Burne JA,Türker KS

更新日期：2012-01-01 00:00:00

abstract：:Mechanisms that could mitigate the effects of hypoxia on neuronal signaling are incompletely understood. We show that axonal performance of a locust visual interneuron varied depending on oxygen availability. To induce hypoxia, tracheae supplying the thoracic nervous system were surgically lesioned and action potentia...

journal_title：Journal of neurophysiology

authors： Money TG,Sproule MK,Cross KP,Robertson RM

更新日期：2016-09-01 00:00:00

abstract：:1. We recorded local field potentials in the parafoveal representation in the primary visual cortex of anesthetized and paralyzed macaque monkeys with a multicontact electrode that provided for sampling of neural activity at 16 sites along a vertical penetration. Differential recordings at adjacent contacts were trans...

journal_title：Journal of neurophysiology

authors： Victor JD,Purpura K,Katz E,Mao B

更新日期：1994-11-01 00:00:00

abstract：:Several models exist for explaining primary visual cortex (V1) orientation tuning. The modified feedforward model (MFM) and the recurrent model (RM) are major examples. We have implemented these two models, at the same level of detail, alongside a few newer variations, and thoroughly compared their receptive-field str...

journal_title：Journal of neurophysiology

authors： Teich AF,Qian N

更新日期：2006-07-01 00:00:00