Head-unrestrained gaze adaptation in the rhesus macaque.

Abstract:

:The ability to adjust the amplitude of gaze shifts in response to persistent visual errors ("gaze adaptation") has been investigated primarily by introducing visual errors at the end of saccades produced by head-restrained primates. Very little is known about the behavior and neural mechanisms underlying gaze adaptation when the head is free to move. We tested alternative hypotheses about the signals that are altered during gaze adaptation by increasing (25 degrees --> 50 degrees ; "forward adaptation") or decreasing (50 degrees --> 25 degrees ; "backward adaptation") the size of large, head-unrestrained gaze shifts. In our three rhesus monkey subjects, changes to primary gaze shift amplitude occurred regardless of the particular combinations of eye and head movements that made up the amplitude-altered gaze shifts. The relative changes to eye and head movements that occurred during adaptation could be predicted based on the magnitude of gaze adaptation and the positions of the eyes in the orbits at gaze onset. These results are consistent with the hypothesis that gaze adaptation occurs at the level of a gaze shift command and inconsistent with hypotheses based on the assumption that gaze adaptation results from alterations to eye- and/or head-specific signals.

journal_name

J Neurophysiol

authors

Cecala AL,Freedman EG

doi

10.1152/jn.90735.2008

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

164-83

issue

1

eissn

0022-3077

issn

1522-1598

pii

90735.2008

journal_volume

101

pub_type

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