Multisensory integration in mesencephalic trigeminal neurons in Xenopus tadpoles.

abstract：:The purpose of the present study was to determine whether retinal activity can support long-term changes in synaptic strength in the developing dorsal lateral geniculate nucleus (LGN) of thalamus. To test for this we made use of a rodent in vitro explant preparation in which retinal afferents and the intrinsic circuit...

journal_title：Journal of neurophysiology

authors： Ziburkus J,Dilger EK,Lo FS,Guido W

更新日期：2009-12-01 00:00:00

abstract：:1. Our previous study showed that two distinct postural modifications occurred when subjects were instructed to step, rather than maintain stance, in response to a backward surface translation: 1) the automatic postural responses to the surfaces perturbation were reduced in magnitude and 2) the anticipatory postural a...

journal_title：Journal of neurophysiology

authors： Burleigh A,Horak F

更新日期：1996-04-01 00:00:00

abstract：:Cortical neurons display two fundamental nonlinear response characteristics: contrast-set gain control (also termed contrast normalization) and response expansion (also termed half-squaring). These nonlinearities could play an important role in forming and maintaining stimulus selectivity during natural viewing, but o...

journal_title：Journal of neurophysiology

authors： Albrecht DG,Geisler WS,Frazor RA,Crane AM

更新日期：2002-08-01 00:00:00

abstract：:An imbalance between the strengths of excitatory and inhibitory synaptic inputs has been proposed as the cellular basis of autism and related neurodevelopmental disorders. Previous studies examining spontaneous levels of excitatory and inhibitory neurotransmission in the forebrain regions of methyl-CpG-binding protein...

journal_title：Journal of neurophysiology

authors： Nelson ED,Bal M,Kavalali ET,Monteggia LM

更新日期：2011-07-01 00:00:00

abstract：:We studied the effect of eye position on visual and pursuit-related activity in neurons in the superior temporal sulcus of the macaque monkey. Altogether, 109 neurons from the middle temporal area (area MT) and the medial superior temporal area (area MST) were tested for influence of eye position on their stimulus-dri...

journal_title：Journal of neurophysiology

authors： Bremmer F,Ilg UJ,Thiele A,Distler C,Hoffmann KP

更新日期：1997-02-01 00:00:00

abstract：:1. Inhibitors of extracellular carbonic anhydrase (CAo) offer much promise as diagnostic tools in the study of the synaptic basis of activity-induced alkaline transients in the brain. However, most of the present information related to the effects of CAo blockers in nervous tissue comes from experiments that involve s...

journal_title：Journal of neurophysiology

authors： Voipio J,Paalasmaa P,Taira T,Kaila K

更新日期：1995-08-01 00:00:00

abstract：:1. Spatiotemporal receptive fields (RFs) for left and right eyes were studied for simple cells in the cat's striate cortex to examine the idea that stereoscopic depth information is encoded via structural differences of RFs between the two eyes. Traditional models are based on neurons that possess matched RF profiles ...

journal_title：Journal of neurophysiology

authors： Ohzawa I,DeAngelis GC,Freeman RD

更新日期：1996-05-01 00:00:00

abstract：:During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non...

journal_title：Journal of neurophysiology

authors： Khakhalin AS

更新日期：2011-09-01 00:00:00

abstract：:Whole cell membrane currents induced by the inflammatory mediators, bradykinin, 5-hydroxytryptamine (5-HT) and prostaglandin E2, were investigated in capsaicin-sensitive dorsal root ganglion (DRG) neurons from newborn rats grown on a monolayer of hippocampal glia without nerve growth factor (NGF). When firmly attached...

journal_title：Journal of neurophysiology

authors： Vyklický L,Knotková-Urbancová H,Vitásková Z,Vlachová V,Kress M,Reeh PW

更新日期：1998-02-01 00:00:00

abstract：:We used optical imaging of intrinsic signals to study the large-scale organization of ferret auditory cortex in response to complex sounds. Cortical responses were collected during continuous stimulation by sequences of sounds with varying frequency, period, or interaural level differences. We used a set of stimuli th...

journal_title：Journal of neurophysiology

authors： Nelken I,Bizley JK,Nodal FR,Ahmed B,King AJ,Schnupp JW

更新日期：2008-04-01 00:00:00

abstract：:Humans with spinal cord injury (SCI) modulate locomotor output in response to limb load. Understanding the neural control mechanisms responsible for locomotor adaptation could provide a framework for selecting effective interventions. We quantified feedback and feedforward locomotor adaptations to limb load modulation...

journal_title：Journal of neurophysiology

authors： Gordon KE,Wu M,Kahn JH,Schmit BD

更新日期：2010-09-01 00:00:00

abstract：:In neuroendocrine cells, hormone release often requires a collective burst of action potentials synchronized by gap junctions. This is the case for the electrically coupled bag cell neurons in the reproductive system of the marine snail, Aplysia californica. These neuroendocrine cells are found in two clusters, and fi...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Colmers PL,Hodgson HM,Magoski NS

更新日期：2014-12-01 00:00:00

abstract：:Olfactory bulb (OB) glomeruli, the initial sites of synaptic processing of odor information, exhibit high levels of nicotinic acetylcholine receptor (nAChR) expression and receive strong cholinergic input from the basal forebrain. The role of glomerular nAChRs in olfactory processing, however, remains to be elucidated...

journal_title：Journal of neurophysiology

authors： D'Souza RD,Parsa PV,Vijayaraghavan S

更新日期：2013-10-01 00:00:00

abstract：:Tissue injury in early life can produce distinctive effects on pain processing, but little is known about the underlying neural mechanisms. Neonatal inflammation modulates excitatory synapses in spinal nociceptive circuits, but it is unclear whether this results directly from altered afferent input. Here we investigat...

journal_title：Journal of neurophysiology

authors： Li J,Walker SM,Fitzgerald M,Baccei ML

更新日期：2009-10-01 00:00:00

abstract：:Several previous studies have shown the existence of Up and Down states and have linked their magnitude (e.g., depolarization level) to the size of sensory-evoked responses. Here, we studied how the temporal dynamics of such states influence the sensory-evoked response to vibrissa deflection. Under alpha-chloralose an...

journal_title：Journal of neurophysiology

authors： Haslinger R,Ulbert I,Moore CI,Brown EN,Devor A

更新日期：2006-09-01 00:00:00

abstract：:Synaptic transmission at the inner hair cell (IHC) afferent synapse, the first synapse in the auditory pathway, is specialized for rapid and reliable signaling. Here we investigated the properties of a hyperpolarization-activated current (I(h)), expressed in the afferent dendrite of auditory nerve fibers, and its role...

journal_title：Journal of neurophysiology

authors： Yi E,Roux I,Glowatzki E

更新日期：2010-05-01 00:00:00

abstract：:Neural regions in the dorsomedial frontal cortex (DMFC), including the supplementary eye field (SEF) and the presupplementary motor area (pre-SMA), are likely candidates for generating top-down control of saccade target selection. To investigate this, we applied electrical microstimulation to these structures while sa...

journal_title：Journal of neurophysiology

authors： Yang SN,Heinen SJ,Missal M

更新日期：2008-04-01 00:00:00

abstract：:Humans and songbirds shape learned vocalizations during a sensorimotor sensitive period or "babbling" phase. The brain mechanisms that underlie the shaping of vocalizations by sensory feedback are not known. We examined song behavior and brain activity in zebra finches during singing as they actively shaped their song...

journal_title：Journal of neurophysiology

authors： Crandall SR,Aoki N,Nick TA

更新日期：2007-01-01 00:00:00

abstract：:1. Some scientists reported that the simple spike (SS) activity was transiently depressed after climbing fiber input, but others reported that predominant population of Purkinje cells increased their SS activity after the complex spike (CS). In the present study, SS activity after spontaneous CS was compared before an...

journal_title：Journal of neurophysiology

authors： Sato Y,Miura A,Fushiki H,Kawasaki T

更新日期：1993-04-01 00:00:00

abstract：:Using microstimulation to imprint meaningful activity patterns into intrinsically highly interconnected neuronal substrates is hampered by activation of fibers of passage leading to a spatiotemporal "blur" of activity. The focus of the present study was to characterize the shape of this blur in the neocortex to arrive...

journal_title：Journal of neurophysiology

authors： Butovas S,Schwarz C

更新日期：2003-11-01 00:00:00

abstract：:Variations in cortical oscillations in the alpha (7-14 Hz) and beta (15-29 Hz) range have been correlated with attention, working memory, and stimulus detection. The mu rhythm recorded with magnetoencephalography (MEG) is a prominent oscillation generated by Rolandic cortex containing alpha and beta bands. Despite its...

journal_title：Journal of neurophysiology

authors： Jones SR,Pritchett DL,Sikora MA,Stufflebeam SM,Hämäläinen M,Moore CI

更新日期：2009-12-01 00:00:00

abstract：:Although species-specific differences in ion channel properties are well-documented, little has been known about the properties of the human Nav1.8 channel, an important contributor to pain signaling. Here we show, using techniques that include voltage clamp, current clamp, and dynamic clamp in dorsal root ganglion (D...

journal_title：Journal of neurophysiology

authors： Han C,Estacion M,Huang J,Vasylyev D,Zhao P,Dib-Hajj SD,Waxman SG

更新日期：2015-05-01 00:00:00

abstract：:We used positron emission tomography to study motor learning by trial and error. Subjects learned sequences of eight finger movements. Tones generated by a computer told the subjects whether any particular move was correct or incorrect. A control condition was used in which the subjects generated moves, but there was ...

journal_title：Journal of neurophysiology

authors： Jueptner M,Frith CD,Brooks DJ,Frackowiak RS,Passingham RE

更新日期：1997-03-01 00:00:00

abstract：:The group I metabotropic glutamate receptor (mGluR) subtype, mGluR1, is highly expressed on the apical dendrites of olfactory bulb mitral cells and thus may be activated by glutamate released from olfactory nerve (ON) terminals. Previous studies have shown that mGluR1 agonists directly excite mitral cells. In the pres...

journal_title：Journal of neurophysiology

authors： Ennis M,Zhu M,Heinbockel T,Hayar A

更新日期：2006-04-01 00:00:00

abstract：:Neurons in both the lateral intraparietal area (LIP) of the monkey parietal cortex and the intermediate layers of the superior colliculus (SC) are activated well in advance of the initiation of saccadic eye movements. To determine whether there is a progression in the covert processing for saccades from area LIP to SC...

journal_title：Journal of neurophysiology

authors： Paré M,Wurtz RH

更新日期：2001-06-01 00:00:00

abstract：:Cervical dystonia (CD) is a movement disorder that involves involuntary turning and twisting of the neck caused by abnormal muscle contraction. Deep brain stimulation (DBS) in the globus pallidus internus (GPi) is used to treat both CD and the motor symptoms of Parkinson's disease (PD). It has been suggested that the ...

journal_title：Journal of neurophysiology

authors： Tang JK,Moro E,Mahant N,Hutchison WD,Lang AE,Lozano AM,Dostrovsky JO

更新日期：2007-08-01 00:00:00

abstract：:Postural sway during quiet stance is attenuated by actively maintained contact of the index finger with a stationary surface, even if the level of applied force (<1 N) cannot provide mechanical stabilization. In this situation, changes in force level at the fingertip lead changes in center of foot pressure by approxim...

journal_title：Journal of neurophysiology

authors： Rabin E,Bortolami SB,DiZio P,Lackner JR

更新日期：1999-12-01 00:00:00

abstract：:Dual whole-cell patch clamp recordings from the soma and dendrites of CA1 pyramidal neurons located in hippocampal slices of adult rats were used to examine the potential mechanisms of phase precession. To mimic phasic synaptic input, 5-Hz sine wave current injections were simultaneously delivered both to the soma and...

journal_title：Journal of neurophysiology

authors： Magee JC

更新日期：2001-07-01 00:00:00

abstract：:The current eye-tracking study examined the influence of reward on oculomotor performance, and the extent to which learned stimulus-reward associations interacted with voluntary oculomotor control with a modified paradigm based on the classical antisaccade task. Participants were shown two equally salient stimuli simu...

journal_title：Journal of neurophysiology

authors： Preciado D,Theeuwes J

更新日期：2018-10-01 00:00:00

abstract：:The high variability of cortical sensory responses is often assumed to impose a major constraint on efficient computation. In the auditory cortex, however, response variability can be very low. We have used in vivo whole cell patch-clamp methods to study the trial-to-trial variability of the subthreshold fluctuations ...

journal_title：Journal of neurophysiology

authors： Deweese MR,Zador AM

更新日期：2004-09-01 00:00:00